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Books > Science & Mathematics > Biology, life sciences > Biochemistry > Proteins
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Protein Geometry, Classification, Topology and Symmetry - A Computational Analysis of Structure (Hardcover, New)
Loot Price: R5,656
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Protein Geometry, Classification, Topology and Symmetry - A Computational Analysis of Structure (Hardcover, New)
Series: Series in Biophysics
Expected to ship within 12 - 19 working days
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Using a geometric perspective, Protein Geometry, Classification,
Topology, and Symmetry reviews and analyzes the structural
principals of proteins with the goal of revealing the underlying
regularities in their construction. It also reviews computer
methods for structure analysis and the automatic comparison and
classification of these structures with an analysis of the
statistical significance of comparing different shapes. Following
an analysis of the current state of protein classification, the
authors explore more abstract geometric and topological
representations, including the occurrence of knotted topologies.
The book concludes with a consideration of the origin of
higher-level symmetries in protein structure. The authors focus on
simple geometric methods that are deterministic rather than
probabilistic and on the more abstract simplifications of protein
structure that allow a better understanding of the overall fold of
the structure. Most of the methods described in this book have
corresponding computer programs. These can be found (as C source
code) at the ftp site of the Division of Mathematical Biology at
the National Institute for Medical Research. This collection of
ideas contains pedagogical material that make it ideal for
post-graduate courses as well as new ideas and results essential
for researchers investigating protein structures.
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