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Books > Medicine > Clinical & internal medicine
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Sirtuin Biology in Medicine - Targeting New Avenues of Care in Development, Aging, and Disease (Paperback)
Loot Price: R3,251
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Sirtuin Biology in Medicine - Targeting New Avenues of Care in Development, Aging, and Disease (Paperback)
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Sirtuin Biology in Medicine: Targeting New Avenues of Care in
Development, Aging, and Disease provides a fascinating and in-depth
analysis of sirtuins in the body during normal physiology as well
during disease highlighting the targeting of sirtuin-controlled
pathways for the development of innovative, efficacious, and safe
therapeutic strategies for multiple disorders in the body that
ultimately can affect lifespan extension. Sirtuins are expressed
throughout the body, have broad biological effects, and can
significantly impact both cellular survival and longevity during
acute and long-term illnesses. These histone deacetylases play an
intricate role in the pathology, progression, and treatment of
several disease entities ranging from neurodegenerative disorders,
cardiovascular disease, immune system dysfunction, reproductive
dysfunction, endocrine disorders, gastrointestinal disease, drug
dependency, and aging-related disorders. Implementing a
translational medicine format, this unique reference highlights
novel signaling pathways for sirtuins that promote stem cell
proliferation, enhance cellular protection, modulate pathways of
apoptosis and autophagy, and extend life span. Each chapter is
presented with insightful detail that will be of interest and a
comprehensive resource to audiences that include scientists,
physicians, pharmaceutical industry experts, nutritionists, and
students.
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