A collection of 28 monographs covering the quality control and
traditional and clinical uses of selected medicinal plants. Plants
were selected for inclusion on the basis of their widespread use,
particularly in countries that rely heavily on medicinal plants to
meet primary health care needs. Monographs are provided for a
number of phytomedicines traditionally used to treat such common
complaints as diarrhoea, constipation, headache, appetite loss,
sleep disorders, fatigue, and mild respiratory, gastrointestinal,
and skin disorders. Additional medical applications assessed range
from the lipid-lowering potential of garlic powder preparations,
through the possible antiplasmodial activity of Fructus Bruceae, to
the role of curcumin in promoting peptic ulcer healing and reducing
the associated abdominal pain. In preparing and publishing these
monographs, WHO aims to encourage standardized scientific
approaches to ensuring the safety, quality and efficacy of
medicinal plants and their products. The monographs are also
intended to promote international harmonization in the quality
control and use of herbal medicines and to serve as models for the
development of national formularies. Draft monographs were
finalized following review by over 100 experts in 40 countries.
Some 1400 references to the literature are included. Each monograph
follows a standard format, with information presented in two parts.
The first gives pharmacopoeial summaries for quality assurance,
botanical features, distribution, identity tests, purity
requirements, chemical assays, and active or major chemical
constituents. A section on definition provides the Latin binomial
pharmacopoeial name, the most important criterion in quality
assurance. Latin pharmacopoeial synonyms and vernacular names,
listed in the section on synonyms and selected vernacular names,
are those names used in commerce or by local consumers. The second
part of each monograph begins with a list of dosage forms and of
medicinal uses categorized as uses supported by clinical data, uses
described in pharmacopoeias and in traditional systems of medicine,
and uses described in folk medicine, but not yet supported by
experimental or clinical data. Each monograph also includes an
extensive review of available data on experimental and clinical
pharmacology, followed by information on contraindications, such as
sensitivity or allergy, warnings, precautions, particularly in such
special groups as pregnant and breast-feeding women, adverse
reactions, and dosage. A list of references concludes the
monograph. Plants covered in volume 1 Bulbus Allii Cepae Bulbus
Allii Sativi Aloe Aloe Vera Gel Radix Astragali Fructus Bruceae
Radix Bupleuri Herba Centellae Flos Chamomillae Cortex Cinnamomi
Rhizoma Coptidis Rhizoma Curcumae Longae Radix Echinaceae Herba
Echinaceae Purpureae Herba Ephedrae Folium Ginkgo Radix Ginseng
Radix Glycyrrhizae Radix Paeoniae Semen Plantaginis Radix Platycodi
Radix Rauwolfiae Rhizoma Rhei Folium Sennae Fructus Sennae Herba
Thymi Radix Valerianae Rhizoma Zingiberis
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