G protein-coupled receptors (GPCRs) transduce signals from a
diverse array of endogenous ligands, including ions, amino acids,
nucleotides, lipids, peptides, and large glycoprotein hormones.
They are also responsible for our sensing of exogenous stimuli,
including photons and odorants. GPCRs regulate almost every aspect
of our physiological functions. It is estimated that 40% to 50% of
currently used therapeutic drugs target GPCRs directly or
indirectly. Because the current drugs target only a small portion
of the GPCRs, opportunities for targeting the remaining GPCRs is
enormous. This volume reviews the latest developments in this
rapidly advancing field.
* This series provides a forum for discussion of new
discoveries, approaches, and ideas * Contributions from leading
scholars and industry experts * Reference guide for researchers
involved in molecular biology and related fields
General
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