Features Represents the first book to provide comprehensive
coverage of model-assisted designs for various types of
dose-finding and optimization clinical trials Describes the
up-to-date theory and practice for model-assisted designs Presents
many practical challenges and issues arising from early-phase
clinical trials Illustrates with many real trial applications
Offers numerous tips and guidance on designing dose finding and
optimization trials Provides step-by-step illustration of using
software to design trials Develops a companion website
(www.trialdesign.org) to provide easy-to-use software to assist
learning and implementing model-assisted designs.
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