With recent studies using genetic, epigenetic, and other molecular
and neurochemical approaches, a new era has begun in understanding
pathophysiology of suicide. Emerging evidence suggests that
neurobiological factors are not only critical in providing
potential risk factors but also provide a promising approach to
develop more effective treatment and prevention strategies. The
Neurobiological Basis of Suicide discusses the most recent findings
in suicide neurobiology. Psychological, psychosocial, and cultural
factors are important in determining the risk factors for suicide;
however, they offer weak prediction and can be of little clinical
use. Interestingly, cognitive characteristics are different among
depressed suicidal and depressed nonsuicidal subjects, and could be
involved in the development of suicidal behavior. The
characterization of the neurobiological basis of suicide is in
delineating the risk factors associated with suicide. The
Neurobiological Basis of Suicide focuses on how and why these
neurobiological factors are crucial in the pathogenic mechanisms of
suicidal behavior and how these findings can be transformed into
potential therapeutic applications.
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