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Chromosome Translocation (Hardcover, 1st ed. 2018)
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Chromosome Translocation (Hardcover, 1st ed. 2018)
Series: Advances in Experimental Medicine and Biology, 1044
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This volume discusses various aspects of mechanisms and
methodologies of chromosome translocations, ranging from a
historical and clinical overview of chromosome translocations to
the rapid development of the next-generation sequencing
technologies, which has dramatically increased our understanding of
the spectrum of chromosome translocations in human diseases. The
book also introduces the mechanistic studies on chromosome
deletions and their implications in cancer, and discusses the
mechanisms of regulating chromothripsis, a unique complex type of
chromosome translocation. It is a valuable resource for students
and researchers alike, providing insights into chromosome
translocations and, potentially, other genomic aberrations involved
in understanding and curing human diseases.
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