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Tuning Autophagy-Inducing Activity and Toxicity for Lanthanide Nanocrystals (Hardcover, 1st ed. 2022) Loot Price: R4,589
Discovery Miles 45 890
Tuning Autophagy-Inducing Activity and Toxicity for Lanthanide Nanocrystals (Hardcover, 1st ed. 2022): Yunjiao Zhang

Tuning Autophagy-Inducing Activity and Toxicity for Lanthanide Nanocrystals (Hardcover, 1st ed. 2022)

Yunjiao Zhang

Series: Springer Theses

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Loot Price R4,589 Discovery Miles 45 890 | Repayment Terms: R430 pm x 12*

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This thesis presents a simple, yet highly effective surface engineering solution that uses non-covalent binding peptides to control the autophagy-inducing activity of nanomaterials and nanodevices. The author presents RE-1, a short synthetic peptide that sequence-specifically binds to lanthanide (LN) oxide and upconversion nanocrystals with high affinity, which was discovered using an innovative phage display approach. RE-1 effectively inhibits the autophagy-inducing activity and toxicity of these nanocrystals by forming a stable coating layer on the surface of the nanoparticles, and by reducing their sedimentation and cell interaction. RE- 1 and its variants provide a versatile tool for tuning cell interactions in order to achieve the desired level of autophagic response and are useful for the various diagnostic and therapeutic applications of LN-based nanomaterials and nanodevices.

General

Imprint: Springer Verlag, Singapore
Country of origin: Singapore
Series: Springer Theses
Release date: 2022
First published: 2022
Authors: Yunjiao Zhang
Dimensions: 235 x 155mm (L x W)
Format: Hardcover
Pages: 156
Edition: 1st ed. 2022
ISBN-13: 978-981-16-8165-3
Categories: Books > Professional & Technical > Technology: general issues > Nanotechnology
Books > Professional & Technical > Biochemical engineering > General
Books > Science & Mathematics > Biology, life sciences > Cellular biology > General
Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology > General
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LSN: 981-16-8165-1
Barcode: 9789811681653

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