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Aging Methods and Protocols (Paperback, Softcover reprint of hardcover 1st ed. 2000)
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Aging Methods and Protocols (Paperback, Softcover reprint of hardcover 1st ed. 2000)
Series: Methods in Molecular Medicine, 38
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Aging is an almost universal process within biological systems, one
which leads to a decline in functional capacity, disease onset, and
eventually death. There has been much interest in recent years to
elucidate the molecular mec- nisms that underlie the aging process.
Many theories have been proposed since the last century that aim to
explain the causes of aging. There is no one theory that completely
satisfies the phenotype of aging, but genetics and environm- tal
factors play an important role in the etiology of age-related
pathologies and the aging process. However, there is still much to
be learned about the aging process which has been termed one of the
last great frontiers in biology. De- graphic changes worldwide are
leading to increased average life expectancies within our
populations. These changes in population characteristics will
impact upon the economies of the supporting society, with
increasing healthcare and infrastructural costs arising from the
prevalence of age-related pathologies and other physical
disabilities associated with advancing years. Many researchers
worldwide are working in the attempt to identify key cellular
processes through which it might one day be possible to slow down
the aging process and thus increase the health span of humans.
Numerous research projects-from the cellular through to tissue,
organ, and whole organism studies-are currently underway to
investigate the mul- factorial aging process.
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