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Mockingly nicknamed Mr Green, he nevertheless believes he can get
away with anything, even murder, if required... About the Author:
Alan Hall is also the author of Saltaire Blonde. In addition, he
has written two books on the history of Bradford. He lives with his
wife Amanda in Saltaire.
Over the past few decades, the book series Linguistische Arbeiten
[Linguistic Studies], comprising over 500 volumes, has made a
significant contribution to the development of linguistic theory
both in Germany and internationally. The series will continue to
deliver new impulses for research and maintain the central insight
of linguistics that progress can only be made in acquiring new
knowledge about human languages both synchronically and
diachronically by closely combining empirical and theoretical
analyses. To this end, we invite submission of high-quality
linguistic studies from all the central areas of general
linguistics and the linguistics of individual languages which
address topical questions, discuss new data and advance the
development of linguistic theory.
This volume consists of nine articles dealing with topics in
distinctive feature theory in various typologically diverse
languages, including Acehnese, Afrikaans, Basque, Dutch, Finnish,
French, German, Hungarian, Japanese, Korean, Navajo, Portuguese,
Tahltan, Terena, Tswana, Tuvan, and Zoque. The subjects dealt with
in the book include feature geometry, underspecification (in
rule-based and in Opti-mality Theoretic treatments) and the
phonetic implementation of phonological features. Other topics
include laryngeal features (e.g. [voice], [spread glottis],
[nasal]), and place features for consonants and vowels. The volume
will be of interest to all linguists and advanced students of
linguistics working on feature theory and/or the
phonetics-phonology interface.
Cut 50% of your meetings and improve the ones that remain.
Meetings are essential to collaboration and decision making, but they are often irrelevant, time consuming and badly run. People spend an average of 2 days per week in meetings and 50% of it is wasted. This book will help you win back that wasted day a week by cutting out the half of face to face and virtual meetings that do not need to happen and radically improving the ones that remain.
The two authors, one an experienced CEO and consultant to major multinationals, the other a millennial line manager working within one of the world’s largest companies, find common ground, and occasional disagreements on creating new ways of meeting both face to face and through technology that are far more engaging and effective for everyone.
The book focuses on three main areas:
- Dealing with the business and corporate cultural challenges in changing the way we meet
- Cutting out the unnecessary topics and participants that make up 50% of todays meetings
- Designing and running faster and more focused face to face and online meetings with more relevant content; clearer decisions and actions, and much higher levels of participation
Full of examples and practical tools that will improve everything from your regular team meetings to management meetings, online conferences, global meetings and big events. This book will lead you through practical actions and targets to kill the meetings that do not need to happen and radically improve the ones that remain.
The Subjectivities and Politics of Occupational Risk links
restructuring in three industries to shifts in risk subjectivities
and politics, both within workplaces and within the safety
management and regulative spheres, often leading to conflict and
changes in law, political discourses and management approaches. The
state and corporate governance emphasis on worker participation and
worker rights, internal responsibility, and self-regulative
technologies are understood as corporate and state efforts to
reconstruct control and responsibility for Occupational Health and
Safety (OHS) risks within the context of a globalized neoliberal
economy. Part 1 presents a conceptual framework for understanding
the subjective bases of worker responses to health and safety
hazards using Bourdieu's concept of habitus and the sociology of
risk concepts of trust and uncertainty. Part 2 demonstrates the
restructuring arguments using three different industry case studies
of multiple mines, farms and auto parts plants. The final chapter
draws out the implications of the evidence and theory for social
change and presents several recommendations for a more
worker-centred politics of health and safety. The book will appeal
to social scientists interested in health and safety, work,
employment relations and labour law, as well as worker advocates
and activists.
brief introductory chapters frame each subsection, providing an
overview of each section and adding an integrative narrative all
chapters include an international dimension and incorporate
international references designed to have broad appeal to multiple
audiences and incorporates the global push in medical schools and
universities generally for interdisciplinary courses and degrees
brief introductory chapters frame each subsection, providing an
overview of each section and adding an integrative narrative all
chapters include an international dimension and incorporate
international references designed to have broad appeal to multiple
audiences and incorporates the global push in medical schools and
universities generally for interdisciplinary courses and degrees
The Subjectivities and Politics of Occupational Risk links
restructuring in three industries to shifts in risk subjectivities
and politics, both within workplaces and within the safety
management and regulative spheres, often leading to conflict and
changes in law, political discourses and management approaches. The
state and corporate governance emphasis on worker participation and
worker rights, internal responsibility, and self-regulative
technologies are understood as corporate and state efforts to
reconstruct control and responsibility for Occupational Health and
Safety (OHS) risks within the context of a globalized neoliberal
economy. Part 1 presents a conceptual framework for understanding
the subjective bases of worker responses to health and safety
hazards using Bourdieu's concept of habitus and the sociology of
risk concepts of trust and uncertainty. Part 2 demonstrates the
restructuring arguments using three different industry case studies
of multiple mines, farms and auto parts plants. The final chapter
draws out the implications of the evidence and theory for social
change and presents several recommendations for a more
worker-centred politics of health and safety. The book will appeal
to social scientists interested in health and safety, work,
employment relations and labour law, as well as worker advocates
and activists.
This authoritative guide offers a vital overview including the
recent fundamental changes in the care of newborn babies. As well
as medical staff, key roles are now played by senior nurses,
clinical nurse specialists, pharmacists, advanced neonatal nurse
practitioners, nurse consultants, midwives, dieticians,
physiotherapists and speech therapists. The involvement of such a
diverse range of professional cultures in such a rapidly developing
area often leads to competing priorities, complicated by a lack of
established guidelines. There is also the added challenge of fetal
medicine - an important emerging allied specialty new to many
healthcare professionals. This book assists all professionals
involved in the provision of neonatal care in understanding the
genetic, physiological and biochemical mechanisms which have either
led to or are associated with the clinical conditions affecting
their patients. With comprehensive chapters on fetal medicine,
genetics, inherited biochemical disorders, fundamental
physiological concepts, the cardiovascular, renal and respiratory
systems, bacterial and transplacental infections, pharmacokinetics,
nutrition, and an overview of haemostasis, A Foundation For
Neonatal Care aids understanding of the continuum of developmental
physiology and pathology which is now required of neonatal care
providers.
This book presents new insights on the phonology-morphology
interface. It discusses a wide range of central theoretical issues,
including the role of paradigms in synchronic grammars, and does so
in the context of a wide variety of languages including several
non-Indo-European< br> languages.
General Description of the Volume:
Small GTPases play a key role in many aspects of contemporary cell
biology: control of cell growth and differentiation; regulation of
cell adhesion and cell movement; the organization of the actin
cytoskeleton; and the regulation of intracellular vesicular
transport. This volume plus its companions Volumes 256 and 257
cover all the biochemical and biological assays currently in use
for analyzing the role of small GTPases in many aspects of cell
biology at the molecular level.
General Description of the Series:
The critically acclaimed laboratory standard for more than forty
years, Methods in Enzymology is one of the most highly respected
publications in the field of biochemistry. Since 1955, each volume
has been eagerly awaited, frequently consulted, and praised by
researchers and reviewers alike. Now with more than 300 volumes
(all of them still in print), the series contains much material
still relevant today--truly an essential publication for
researchers in all fields of life sciences.
Key Features
* Expression, purification, and posttranslational
modification
* Guanine nucleotide exchange and hydrolysis
* Cell expression and analysis "in Vitro"
* Biological activity
The critically acclaimed laboratory standard for more than forty
years, Methods in Enzymology is one of the most highly respected
publications in the field of biochemistry. Since 1955, each volume
has been eagerly awaited, frequently consulted, and praised by
researchers and reviewers alike. Now with over 400 volumes (all of
them still in print), the series contains much material still
relevant today-truly an essential publication for researchers in
all fields of life sciences.
Methods in Enzymology is now available online at ScienceDirect -
full-text online of volumes 1 onwards. For more information about
the Elsevier Book Series on ScienceDirect Program, please
visit:
http: //www.info.sciencedirect.com/bookseries/
This volume is the first of two planned volumes on the topic of
small GTPases and their role in disease.
The critically acclaimed laboratory standard for more than 40
years, "Methods in Enzymology" is one of the most highly respected
publications in the field of biochemistry. Since 1955, each volume
has been eagerly awaited, frequently consulted, and praised by
researchers and reviewers alike. Now with over 400 volumes (all of
them still in print), the series contains much material still
relevant today-truly an essential publication for researchers in
all fields of life sciences.
"Methods in Enzymology" is now available online at ScienceDirect
- full-text online of volume 1 onward. For more information about
the Elsevier Book Series on ScienceDirect Program, please
visit:
http: //www.info.sciencedirect.com/bookseries/
This volume is the second of two planned volumes on the topic of
small GTPases and their role in disease.
The Ras superfamily (>150 human members) encompasses Ras GTPases
involved in cell proliferation, Rho GTPases involved in regulating
the cytoskeleton, Rab GTPases involved in membrane targeting/fusion
and a group of GTPases including Sar1, Arf, Arl and dynamin
involved in vesicle budding/fission. These GTPases act as molecular
switches and their activities are controlled by a large number of
regulatory molecules that affect either GTP loading (guanine
nucleotide exchange factors or GEFs) or GTP hydrolysis (GTPase
activating proteins or GAPs). In their active state, they interact
with a continually increasing, functionally complex array of
downstream effectors.
Since the last Methods in Enzymology volume on this topic in 2000,
the study of Ras Family GTPases has witnessed a plethora of new
directions and trends. With regards to the founding member of the
Ras superfamily, the study of Ras in oncogenesis has seen the
development and application of more advanced model cell culture and
animal systems. The discovery of mutationally activated B-Raf in
human cancers has injected renewed interest in this classical
effector pathway of Ras.
*Includes a database for Ras family proteins and their effectors
and regulators
*Complimentary to volume 406 coverage of the Rho family
*Over 150 international contributors
The Ras superfamily (>150 human members) encompasses Ras GTPases
involved in cell proliferation, Rho GTPases involved in regulating
the cytoskeleton, Rab GTPases involved in membrane targeting/fusion
and a group of GTPases including Sar1, Arf, Arl and dynamin
involved in vesicle budding/fission. These GTPases act as molecular
switches and their activities are controlled by a large number of
regulatory molecules that affect either GTP loading (guanine
nucleotide exchange factors or GEFs) or GTP hydrolysis (GTPase
activating proteins or GAPs). In their active state, they interact
with a continually increasing, functionally complex array of
downstream effectors.
Since the last Methods in Enzymology volume on this topic in 2000,
Rho GTPases have continued to receive a huge amount of attention.
The human genome sequence has revealed the full extent of the Rho
GEF and Rho GAP families (over 80 members for each) and the
challenge of identifying the molecular interactions and cellular
pathways influenced by each of these regulators is a daunting
prospect. This new volume describes some of the methods currently
being used to examine Rho family GTPase regulation at the
biochemical and cellular level.
*Describes the methods currently being used to examine Rho family
GTPase regulation at the biochemical and cellular levels.
*Includes new imaging techniques that revolutionize the ability to
visualize GTPase activities.
*Over 150 international contributors.
Rab GTPases now comprise a family of >63 members. They are
emerging as the key hub element controlling the membrane
architecture of eukaryotic cells. They are intimately involved in
vesicle targeting and fusion in both the endocytic and exocytic
pathways and direct the assembly and disassembly of protein
complexes that include regulators (GEFs and GAPs), effectors
(tethers/motors) and fusion components (SNAREs) that control
membrane targeting and fusion. During the last 3 years the field
has virtually exploded with the identification and characterization
of many new Rab proteins and their effectors.
Our understanding of how Rab GTPases control membrane function
remains at its infancy. This volume of MIE provides a wealth of new
concepts, approaches and tools to study Rab proteins in the test
tube and in living cells that will be of strong benefit to both
established laboratories and new investigators in the field to
elucidate Rab GTPase function in cellular development,
differentiation and proliferation.
* Comprehensive overview of Rab GTPase phylogeny and systems
biology
* Identification and characterization of Rab GEFs, GAPs and
effectors
* General methodologies to study Rab GTPase function in vitro and
in vivo using biochemical, molecular and microscopy approaches
The Story of Bradford traces the city's history from earliest times
to the present, concluding with comments on the issues, challenges
and opportunities that the 21st century will present. The departure
of the German wool merchants in 1914 and the tragedy that befell
the Bradford Pals at the Somme had a serious effect not just on the
city but further afield, while the achievements of the great
nineteenth-century wool barons are contrasted with the condition of
the working-class and industrial unrest. The challenge in the new
millennium is for Bradford to use its considerable assets -
including the architectural development and heritage - to shine as
a prosperous and self-confident community.
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