This is the first book that critically examines the reform of the Appellate Body (AB) of the World Trade Organization (WTO) in light of the current crisis resulting from the U.S. blocking of the appointment of its members. The reform of the AB is critical, as the appointment crisis could lead to the demise of "the jewel in the crown," which may even cause the dismantling of the WTO as a whole. This book covers various aspects of the crisis and its reform. Specifically, as the crisis cannot be fully understood without reviewing the role of the AB from the broader perspectives of the other functions of the WTO, the book examines the reform of the AB from the broader perspectives of the WTO governance. Additional focus is on the reform of the AB in relation to its specific functions. Available options are provided to address the AB crisis, as well as discussion of wider implications beyond the WTO. Contributed by world-renowned academics, experts, and practitioners in the field of international economic law, this volume provides a comprehensive analysis of the AB crisis and its solutions.

Designing Human Interface in Speech Technology bridges a gap between the needs of the technical engineer and cognitive researchers working in the multidisciplinary area of speech technology applications. The approach is systematic and the focus is on the utility of developing and designing speech related products.

Included is coverage of topics such as neuroscience on the multimodal cortex, cognitive theories on multi-task performance, stress and workload, as well as human information process theory and ecological interface design theory for evaluating speech-related human-system interfaces.

Of special emphasis are topics such as spoken dialogue system design, in-vehicle communication system design and speech technology in military applications. Also included are tools on how to analyze the design, different design theories and process, methods about how to understand users. The material systematically describes the user-center design process and usability evaluation methods.

Designing Human Interface in Speech Technology is appropriate for designers, engineers, and decision makers working in the area of speech technology research. It is also a good text book for senior university students and postgraduate students in the respective interaction design areas.

This book gives an overview of the research and application of speech technologies in different areas. One of the special characteristics of the book is that the authors take a broad view of the multiple research areas and take the multidisciplinary approach to the topics. One of the goals in this book is to emphasize the application. User experience, human factors and usability issues are the focus in this book.

Artificial Intelligence (AI) is changing the world around us, and it is changing the way people are living, working, and entertaining. As a result, demands for understanding how AI functions to achieve and enhance human goals from basic needs to high level well-being (whilst maintaining human health) are increasing. This edited book systematically investigates how AI facilitates enhancing human needs in the digital age, and reports on the state-of-the-art advances in theories, techniques, and applications of humanity driven AI. Consisting of five parts, it covers the fundamentals of AI and humanity, AI for productivity, AI for well-being, AI for sustainability, and human-AI partnership. Humanity Driven AI creates an important opportunity to not only promote AI techniques from a humanity perspective, but also to invent novel AI applications to benefit humanity. It aims to serve as the dedicated source for the theories, methodologies, and applications on humanity driven AI, establishing state-of-the-art research, and providing a ground-breaking book for graduate students, research professionals, and AI practitioners.

This book presents the essential knowledge and legal practice for establishing and operating companies in China. The book includes 6 chapters: Establishment of a Company; Shareholders, Directors, Supervisors, Senior Executives; Investment, M&A and Creditor's Rights; Financing and Guarantee; Alteration, Liquidation and Cancellation; Malfeasance Most Likely to be Overlooked. The end is a summary of the laws and regulations involved in the chapters above. From a professional perspective, this book explains and analyzes the key points, practical difficulties and potential risks that an enterprise may encounter in the process of establishment and operation, describes in detail the key points for handling various businesses and matters, the notes for selection of different administrative procedures, and conducts multi-dimensional comparison and case analysis to facilitate readers' understanding. This book is a practical guide for everyone to understand how to establish and operate a company in China, which is not only suitable for readers who want to start a business or have already started a business, but also suitable for overseas investors to fully understand how to establish and operate a company in China. It is also helpful for investors and entrepreneurs to lead the enterprise to be more standardized and more compliant so as to achieve better operation and development. In addition, this book could be used as a reference book for legal and financial professionals to help professionals become more professional.

The ban on sales of ZTE, imposed by the US, made China feel the weight of a small chip. The ban is termed as a trade war. What is the truth behind this trade friction? Why did the Chinese microchip industry encounter such a predicament? What is the future of the microchip industry in China? This book tried to answer these questions, uncovers the secrets of China's microchip industry, and traces its development. It looks at bridging the gap between the chip technology and public perception, and predicts how China can make a breakthrough in this industry. The book takes a 'macro-history view' to describe the race among superpowers in the microchip industry and records people's constant explorations into the industry in the past six decades. It also compares the microchip industry in China to that of United States, Japan, and South Korea.

The ban on sales of ZTE, imposed by the US, made China feel the weight of a small chip. The ban is termed as a trade war. What is the truth behind this trade friction? Why did the Chinese microchip industry encounter such a predicament? What is the future of the microchip industry in China? This book tried to answer these questions, uncovers the secrets of China's microchip industry, and traces its development. It looks at bridging the gap between the chip technology and public perception, and predicts how China can make a breakthrough in this industry. The book takes a 'macro-history view' to describe the race among superpowers in the microchip industry and records people's constant explorations into the industry in the past six decades. It also compares the microchip industry in China to that of United States, Japan, and South Korea.

This book presents the essential knowledge and legal practice for establishing and operating companies in China. The book includes 6 chapters: Establishment of a Company; Shareholders, Directors, Supervisors, Senior Executives; Investment, M&A and Creditor's Rights; Financing and Guarantee; Alteration, Liquidation and Cancellation; Malfeasance Most Likely to be Overlooked. The end is a summary of the laws and regulations involved in the chapters above. From a professional perspective, this book explains and analyzes the key points, practical difficulties and potential risks that an enterprise may encounter in the process of establishment and operation, describes in detail the key points for handling various businesses and matters, the notes for selection of different administrative procedures, and conducts multi-dimensional comparison and case analysis to facilitate readers' understanding. This book is a practical guide for everyone to understand how to establish and operate a company in China, which is not only suitable for readers who want to start a business or have already started a business, but also suitable for overseas investors to fully understand how to establish and operate a company in China. It is also helpful for investors and entrepreneurs to lead the enterprise to be more standardized and more compliant so as to achieve better operation and development. In addition, this book could be used as a reference book for legal and financial professionals to help professionals become more professional.

This is the first book that critically examines the reform of the Appellate Body (AB) of the World Trade Organization (WTO) in light of the current crisis resulting from the U.S. blocking of the appointment of its members. The reform of the AB is critical, as the appointment crisis could lead to the demise of "the jewel in the crown," which may even cause the dismantling of the WTO as a whole. This book covers various aspects of the crisis and its reform. Specifically, as the crisis cannot be fully understood without reviewing the role of the AB from the broader perspectives of the other functions of the WTO, the book examines the reform of the AB from the broader perspectives of the WTO governance. Additional focus is on the reform of the AB in relation to its specific functions. Available options are provided to address the AB crisis, as well as discussion of wider implications beyond the WTO. Contributed by world-renowned academics, experts, and practitioners in the field of international economic law, this volume provides a comprehensive analysis of the AB crisis and its solutions.

With an evolutionary advancement of Machine Learning (ML) algorithms, a rapid increase of data volumes and a significant improvement of computation powers, machine learning becomes hot in different applications. However, because of the nature of "black-box" in ML methods, ML still needs to be interpreted to link human and machine learning for transparency and user acceptance of delivered solutions. This edited book addresses such links from the perspectives of visualisation, explanation, trustworthiness and transparency. The book establishes the link between human and machine learning by exploring transparency in machine learning, visual explanation of ML processes, algorithmic explanation of ML models, human cognitive responses in ML-based decision making, human evaluation of machine learning and domain knowledge in transparent ML applications. This is the first book of its kind to systematically understand the current active research activities and outcomes related to human and machine learning. The book will not only inspire researchers to passionately develop new algorithms incorporating human for human-centred ML algorithms, resulting in the overall advancement of ML, but also help ML practitioners proactively use ML outputs for informative and trustworthy decision making. This book is intended for researchers and practitioners involved with machine learning and its applications. The book will especially benefit researchers in areas like artificial intelligence, decision support systems and human-computer interaction.

This book gives an overview of the research and application of speech technologies in different areas. One of the special characteristics of the book is that the authors take a broad view of the multiple research areas and take the multidisciplinary approach to the topics. One of the goals in this book is to emphasize the application. User experience, human factors and usability issues are the focus in this book.

Bridging the gap between the needs of the technical engineer and cognitive researchers related to speech technology applications.

Systematic approach focusing on the utility of speech related product design

Designed to respond to the growing need for specific theories, tools and methods for design, testing and evaluating speech related human-system interfaces.

Targeted at designers, engineers, and decision makers working in the area of speech technology research

With an evolutionary advancement of Machine Learning (ML) algorithms, a rapid increase of data volumes and a significant improvement of computation powers, machine learning becomes hot in different applications. However, because of the nature of "black-box" in ML methods, ML still needs to be interpreted to link human and machine learning for transparency and user acceptance of delivered solutions. This edited book addresses such links from the perspectives of visualisation, explanation, trustworthiness and transparency. The book establishes the link between human and machine learning by exploring transparency in machine learning, visual explanation of ML processes, algorithmic explanation of ML models, human cognitive responses in ML-based decision making, human evaluation of machine learning and domain knowledge in transparent ML applications. This is the first book of its kind to systematically understand the current active research activities and outcomes related to human and machine learning. The book will not only inspire researchers to passionately develop new algorithms incorporating human for human-centred ML algorithms, resulting in the overall advancement of ML, but also help ML practitioners proactively use ML outputs for informative and trustworthy decision making. This book is intended for researchers and practitioners involved with machine learning and its applications. The book will especially benefit researchers in areas like artificial intelligence, decision support systems and human-computer interaction.

Artificial Intelligence (AI) is changing the world around us, and it is changing the way people are living, working, and entertaining. As a result, demands for understanding how AI functions to achieve and enhance human goals from basic needs to high level well-being (whilst maintaining human health) are increasing. This edited book systematically investigates how AI facilitates enhancing human needs in the digital age, and reports on the state-of-the-art advances in theories, techniques, and applications of humanity driven AI. Consisting of five parts, it covers the fundamentals of AI and humanity, AI for productivity, AI for well-being, AI for sustainability, and human-AI partnership. Humanity Driven AI creates an important opportunity to not only promote AI techniques from a humanity perspective, but also to invent novel AI applications to benefit humanity. It aims to serve as the dedicated source for the theories, methodologies, and applications on humanity driven AI, establishing state-of-the-art research, and providing a ground-breaking book for graduate students, research professionals, and AI practitioners.

This book summarizes the current knowledge of anthocyanins, provides systematic information for future exploration of anthocyanin applications. It focuses on several aspects regarding the studying progression in the field of anthocyanins. The first section of the book provides a brief introduction to the scope and progress on anthocyanins, which is followed by the second section that describes the natural sources, structure, extraction approaches, bioavailability, and current stabilizing approach of anthocyanins. Then in the third part, the book focuses on the industrial processing of anthocyanins in foods by discussing the impact of food processing on anthocyanin structure and composition as well as classical processing techniques on anthocyanin-containing foods, including high-pressure, encapsulation, microwave, and combined application of the above techniques. In the last section of the book, the authors explore the currently most popular application of anthocyanins in improving human health, such as the effect of anthocyanin on vision, metabolism, neural system, cardiovascular system, and cancers. The book will facilitate readers’ understanding of the progress of anthocyanin studies. And it will benefit researchers and graduate students in the fields of natural products, functional food, and nutrition, etc. 

This book constitutes the proceedings of the 14th International Conference on Verification and Evaluation of Computer and Communication Systems, VECoS 2020, which was supposed to be held in Xi'an, China, in October 2020, but was held virtually instead. The 19 full papers and 1 short paper presented in this volume were carefully reviewed and selected from 60 submissions. The aim of the VECoS conference is to bring together researchers and practitioners in the areas of verification, control, performance, and dependability evaluation in order to discuss state of the art and challenges in modern computer and communication systems in which functional and extra-functional properties are strongly interrelated. Thus, the main motivation for VECoS is to encourage the cross-fertilization between various formal verification and evaluation approaches, methods and techniques, and especially those developed for concurrent and distributed hardware/software systems. The papers are organized in the following topical sections: petri-net, simulation, and scheduling; formal modeling and verification, testing; and artificial intelligence and machine learning.

This book constitutes the refereed proceedings of the 17th International Symposium on Automated Technology for Verification and Analysis, ATVA 2019, held in Taipei, Taiwan in October 2019. The 24 regular papers presented together with 3 tool papers were carefully reviewed and selected from 65 submissions. The symposium is dedicated to the promotion of research on theoretical and practical aspects of automated analysis, verification and synthesis by providing a forum for interaction between the regional and the international research communities and industry in the field. The papers focus on cyber-physical systems; runtime techniques; testing; automata; synthesis; stochastic systems and model checking.

Despite many encouraging developments in the field of animal-free technologies, well-defined animal models are still needed to study fundamental properties of human diseases and to develop new prophylactic and therapeutic treatments against human diseases. Non-human primates (NHP) make up only a small, but important, part of the total number of animals used in biomedical and preclinical research. Due to their close phylogenetic relationship and the shared susceptibility to many human diseases, NHP can provide important research models to study these diseases and, as such, play a critical role in the advancement of various areas in the medical field. Studies in NHP have contributed to our understanding of various diseases and fundamental biological phenomena and they continue to be important in the development of new therapies, treatments, drugs and vaccines. Moreover, NHP models also contribute to our general knowledge of the processes that underlie non-disease and disease conditions. Important areas where NHP can provide important information include (emerging) infectious diseases, organ transplantation, neurological and aging-related disorders. Although not covered in this book due to time constraints, the need for, and benefits of, NHP models has been demonstrated most recently in the SARS-CoV-2 pandemic. The present book is the second of two volumes and covers important disease areas where NHP are used as model species. This volume includes different chapters on NHP models in infectious diseases, aging, neurodegenerative disorders, organ transplantation and cancer.

Organ transplantation has revolutionized the treatment for end-stage organ failure. Immunosuppression is still a major approach currently used in the prevention and treatment of allograft rejection. Both editors Dr. Chen and Dr. Qian have been contributing to preclinical evaluation of immunosuppressants for more than 25 years in North America. Experts from the United States, Canada, the United Kingdom, China, Japan, Germany, Sweden, Hungary and Brazil contributed 23 chapters to this book, providing details of immunological basis in transplantation. They also describe six classes of immunosuppressive agents (calcineurin inhibitors, mTOR inhibitors, JAK-STAT inhibitors, antiproliferative agents, costimulation blockers and corticosteroids), as well as ischemia/reperfusion injury treated agents. Additionally, the new development of cell therapy in the induction of transplant tolerance is introduced. This book provides many important references for the research direction of novel immunosuppressants. Readers that will find this book useful include transplant physicians, surgeons, nurses, immunologists, pharmacologists, pharmacists, medical students, residents and trainees in transplantation.

Organ transplantation is one of the best therapeutic options for patients with end-stage organ failure. Experimental organ transplantation is an important link between basic science and clinical practice. Both editors, Dr Chen and Dr Qian, have been working in this area for over 20 years. Experts from the United States, Canada, China, Japan, Italy, Span, Turkey, Switzerland, Hungary, and Brazil contributed 25 chapters in this book, and provided detailed descriptions of techniques for vascularised organ allografts in mice, rats, pigs, and non-human primates, as well as detailed descriptions of non-vascularised pancreatic islet and spleen allografts. Furthermore, they discussed new advances in transplantation immunology. This book provides numerous important references which were carefully selected by the authors to extend their visions and knowledge. The appropriate readers of this book include medical students, graduate students, residents, surgeons, physicians and immunologists interested in the transplantation area.

The dimensional and dimensionless model formulating the melting and freezing processes in the melting and freezing rotating device (MFRD) are presented. The heat transfer process between the two concentric cylinders with D/ro >0.01 may be considered as that between two parallel plates with a distance of D between them. The theoretical analysis about solidification or melting of a slab at a constant boundary temperature, which is greater or lower than the melting point, is conducted. The theoretical and numerical analysis of the Quasi-Steady state with the moving phase boundaries of the melting and freezing processes in the dimensionless system are performed. Moreover, the properties in MFRD are analyzed. The use of MFRD in the aerospace is discussed.

Die internationale Tagung Processes of Social Reorientation within the Social Structure aus der die Beitr ge zu diesem Buch resultieren, wurde in Kooperation der Freien Universit t Berlin mit dem Bundesministerium f r Arbeit und Soziales durchgef hrt. Sie fand vom 31.1.2007 bis 1.2.2007 in den R umlichkeiten des Bundesministeriums in Berlin statt. Am 1.2.2008 wurde das internationale Netzwerk S.U.P.I Social Uncertanty, Precarity, Inequality gegr ndet, um die schon mehrj hrig bestehenden Arbeitszusammenh nge zwischen den betei-ligten Wissenschaftlern zu institutionalisieren und zu professionalisieren. Um das wachsende Ph nomen der prek ren Arbeitsverh ltnisse und seinen Einfluss auf den Arbeitsmarkt und die Gesellschaft zu verstehen, m ssen auf einem europ ischen Level vor-rangig zwei Aspekte herausgestellt werden: die konomische Krise und die Arbeitsmarktre-formen. Ein europ isches Projekt, das auch politisch Einfluss auf die Reorganisation des pro-duktiven konomischen Systems mit den Anforderungen eines neuen Sozialsystems nimmt, wird in der augenblicklichen Situation dringend ben tigt. Die Herausforderung f r die Kapa-zit ten des Europ ischen Sozialmodells hat die unterschiedlichen Erfahrungen der Mitglieds-staaten der Europ ischen Union und die jeweiligen Beziehungen zwischen Institutionen und B rgern zu ber cksichtigen. Der Entwurf eines stabilen Europ ischen Sozialmodells muss die individuellen Rechte und kollektiven Notwendigkeiten herausarbeiten, um es in Relation zu pragmatischen Umsetzungsstrategien zu positionieren. Erste Bausteine auf dem Weg zu einer konstruktiven Auseinandersetzung ber die Einfl sse und Effekte atypischer Besch ftigungsverh ltnisse auf die europ ischen Gesellschaften wur-den f r diesen Band erarbeitet. Vor dem Hintergrund unterschiedlicher Erfahrungen werden von den Autoren in inter- und intradisziplin ren Beitr gen Zustandsbeschreibungen, Gegen-wartsanalysen und Perspektiven vorgestellt.

Due to the phylogenetic relationship and close genetic and biological similarities with humans, non-human primates (NHP) are regularly used in biomedical and behavioural research. However, because of their highly developed cognitive abilities and social skills, the use of these animals in biomedical research is debated more and more. Although it is acknowledged that in specific research areas NHP are still essential, it is recognized that the use of these animals can only be done under strict conditions under the most optimal welfare aspects. Welfare aspects include housing conditions, non-invasive methods and application of the 3Rs policy. Although many refinement methods have been described in nationally and internationally accepted guidelines on animal laboratory practice, recognition of the guidelines is unfortunately not universal. The present book covers a wide range of NHP models in preclinical research and welfare issues. The following chapters will cover: refinement of the use of NHP in biomedical research; NHP ethics and regulations in Europe; biological basis differences in the human and NHP; the major histocompatibility complex (MHC) immunology in NHP; stem cell biology in NHP; neuro and gliogenesis in an NHP ischemia stroke model; NHP models in autoimmune disease, organ transplantation and infectious disease research; viral diseases in NHP; NHP models in Parkinson's disease, in neurodegenerative disorders research and in cardio-cerebrovascular disease research; islet transplantation; ophthalmic diseases research and neurophysiology in NHP; transgenic engineering in NHP; NHP models of cancers; NHP models in respiratory disease research; NHP models in clinical and non-clinical pharmacology; NHP models in lung transplantation; and aging research in NHP. This book encapsulates a large volume of knowledge scientists have achieved in the field of nonhuman primate models in preclinical research. The editors have invited experts from the United States, Canada, and Europe to contribute 23 chapters in their respective fields of their expertise.

Experimental surgery is an important link for the development in clinical surgery, research and teaching. Experimental surgery was part of the most important surgical discoveries in the past century. Since 1901 nine Nobel Prizes have been awarded to the pioneers had remarkable achievements in the basic or practical surgery. In recent 20 years, experimental surgery has achieved new advances, like laparoscopic and robotic surgery, tissue engineering, and gene therapy which are widely applied in clinic surgery. The present book covers wide experimental surgery in preclinical research models subdivided in two volumes. Volume I introduces surgical basic notions, techniques, and different surgical models involved in basic experimental surgery and review the biomechanical models, ischemia/reperfusion injury models, repair and regeneration models, and organ and tissue transplantation models, respectively. Volume II introduces several specific experimental models such as laparoscopic and bariatric experimental surgical models. The second volume also introduces graft-versus-host disease, and other experimental models. Review the advances and development of recent techniques such as tissue engineering, organ preservation, wound healing and scarring, gene therapy and robotic surgery. The book documents the enormous volume of knowledge we have acquired in the field of experimental surgery. In this book, we have invited experts from the United States, Canada, France, Germany, China, Japan, Korea, UK, Sweden, Netherland, Hungary and Turkey to contribute 36 chapters in the fields of their expertise. These two volumes are the compilation of basic experimental surgery and updated advances of new development in this field that will be invaluable to surgeons, residents, graduate students, surgical researchers, physicians, immunologists, veterinarians and nurses in surgery.

Experimental surgery is an important link for the development in clinical surgery, research and teaching. Experimental surgery was part of the most important surgical discoveries in the past century. Since 1901 nine Nobel Prizes have been awarded to the pioneers had remarkable achievements in the basic or practical surgery. In recent 20 years, experimental surgery has achieved new advances, like laparoscopic and robotic surgery, tissue engineering, and gene therapy which are widely applied in clinic surgery. The present book covers wide experimental surgery in preclinical research models subdivided in two volumes. Volume I introduces surgical basic notions, techniques, and different surgical models involved in basic experimental surgery and review the biomechanical models, ischemia/reperfusion injury models, repair and regeneration models, and organ and tissue transplantation models, respectively. Volume II introduces several specific experimental models such as laparoscopic and bariatric experimental surgical models. The second volume also introduces graft-versus-host disease, and other experimental models. Review the advances and development of recent techniques such as tissue engineering, organ preservation, wound healing and scarring, gene therapy and robotic surgery. The book documents the enormous volume of knowledge we have acquired in the field of experimental surgery. In this book, we have invited experts from the United States, Canada, France, Germany, China, Japan, Korea, UK, Sweden, Netherland, Hungary and Turkey to contribute 36 chapters in the fields of their expertise. These two volumes are the compilation of basic experimental surgery and updated advances of new development in this field that will be invaluable to surgeons, residents, graduate students, surgical researchers, physicians, immunologists, veterinarians and nurses in surgery.