Innovation in areas such as power supplies, size reduction, biocompatibility, durability and lifespan is leading to a rapid increase in the range of devices and applications in the field of implantable biomedical microsystems, which are used for monitoring, diagnosing, and controlling the activities of the human body.

This book provides comprehensive coverage of the fundamental design principles for implantable systems, as well as several major application areas. Each component in an implantable system is described, and major case studies demonstrate how these systems can be designed and optimized for specific design objectives.

Beside low-power signal processing electronics for implantable systems, further topics covered include signal processing hardware, sensor selection, wireless telemetry devices, new types of bio-transducers, power management solutions, system integration techniques, computational algorithms, device packaging, and security measures.

Case studies include studies on implantable neural signal processors, brain-machine interface (BMI) systems, implantable pressure sensors, pacemakers, neural prosthesis, cochlear implant systems, bladder pressure monitoring for treating urinary incontinence, and drug delivery for cancer patients.

Implantable Biomedical Microsystems is the first comprehensive coverage of bioimplantable system design providing an invaluable information source for researchers in Biomedical, Electrical, Computer, Systems, and Mechanical Engineering as well as Engineers involved in design and development of implantable electronic systems and, more generally, Engineers working on low-power wireless applications.
First time comprehensive coverage of system-level and component-level design and engineering aspects for implantable microsystems.
Provides insight into a wide range of proven applications and application specific design trade-offs of bioimplantable systems, including several major case studies.
Enables Engineers involved in development of implantable electronic systems to optimize applications for specific design objectives."

Ageing populations have gradually become a major concern in many industrialised countries over the past fifty years, drawing the attention of both politics and science. The target of a raft of health and social policies, older people are often identified as a specific, and vulnerable, population. At the same time, ageing has become a specialisation in many disciplines - medicine, sociology, psychology, to name but three - and a discipline of its own: gerontology. This book questions the framing of old age by focusing on the relationships between policy making and the production of knowledge. The first part explores how the meeting of scientific expertise and the politics of old age anchors the construction of both individual and collective relationships to the future. Part II brings to light the many ways in which issues relating to ageing can be instrumentalised and ideologised in several public debate arenas. Part III argues that scientific knowledge itself composes with objectivity, bringing ideologies of its own to the table, and looks at how this impacts discourse about ageing. In the final part, the contributors discuss how the frames can themselves be experienced at different levels of the division of labour, whether it is by people who work on them (legislators or scientists), by people working with them (professional carers) or by older people themselves. Unpacking the political and moral dimensions of scientific research on ageing, this cutting-edge volume brings together a range of multidisciplinary, European perspectives, and will be of use to all those interested in old age and the social sciences.

An intriguing look at the history of alcoholism and its dramatic effects, from the first fermented grape to current advances in genetic research. Alcoholism tells the story of a disease familiar to many yet not well understood. It is the first "biography" of alcohol abuse that gauges its devastating effects on the body, the family, the economy, and the community. Alcoholism provides the latest understanding of the disease as a behavioral dysfunction and a biological condition. Coverage includes the origins of alcohol and the discovery of alcoholism as a medical disease; the biology of alcoholism and its effects on the body; and current diagnostic and treatment methods for alcoholism. In addition, the book explores the effects on society of such alcoholism-related problems as domestic abuse, fetal alcohol syndrome, drunk driving, and suicide, as well as promising new directions in alcoholism research, awareness, treatment, and prevention.

Medical histories of Belgium reshapes Belgian history of medicine by bringing together a new generation of scholars. Going beyond a chronological narrative, the book offers new insights by questioning classic themes of the history of medicine: physicians, institutions and the nation state. While retracing specific Belgian characteristics, it also engages with broader European developments in the nineteenth and twentieth centuries. Medical histories of Belgium will appeal to Historians of Belgium in various subfields, especially cultural history and political history and medical historians and medical practitioners seeking the historical context of their activities. -- .

Davanti Nella Gara, an Italian bicycle company, makes the best racing bikes in the world. But after decades of market dominance, competitors have brought the industry leader back to the Peloton. The company's second-generation owner longs for retirement, but a tired product lineup is pushing down profits and the firm's market value will never support his ride into the sunset. The flawed but beloved owner seeks out the counsel of an old friend and successful businessman, who steers him toward a fast and remarkable transformation, one fueled by a relentless focus on innovation excellence. An engaging business novel, Winning Innovation dives into the art and science of innovation; the thrills of the European bike-racing circuit; the vibrant landscape and cuisine of Italy; and a cast of intriguing characters who work to put Davanti on the road to sustained prosperity. The company's leader isn't afraid to learn and apply new ideas to reenergize his company, and finds he cares more about his employees than he could ever imagine. A young innovator struggles to see a product idea to fruition as well as rise into management - and he falls in love along the way. A newly promoted R&D director brings teamwork and transparency to product development and aligns the entire company around innovation. With the help of a seasoned and persistent change agent, in just a year, Davanti deploys a well-defined and -sequenced transformation - a complete and seamless process that can be replicated and scaled by most companies. The leader engages associates in pursuit of the right vision and strategy, candidly supporting them all as they unleash their creative sparks, work through personality conflicts, and take on real-world challenges faced by companies every day. They learn and apply traditional R&D principles in new ways (e.g., cost of delay, sprints, fail fast, late start) and successfully leverage emerging innovation and change-management principles (e.g., idea-creation events, knowledge management, workplace humility, visual management, lean project management). And an aligned, three-phase innovation process - from idea creation to technology development and product design - provides the innovation infrastructure the company needs for revenue creation and success beyond racing bikes. From a top-heavy organization dominated by power struggles and finger-pointing emerges a new Davanti Nella Gara - a flattened, innovative company with: Clear vision and endorsed goals and strategy Speed, responsiveness, and agility Widespread, successful creativity Collaboration and teamwork Superior risk management Respect for people Unquestionable ethics Changed leadership and associate behaviors Project management excellence Rapid problem-solving and experimentation Not just the story of an R&D transformation, Winning Innovation illustrates a companywide transformation of a magnitude that only superior R&D can make possible. It may well be the first book to chronologically introduce the principles for a complete innovation excellence transformation along with the parallel people transformation that is necessary for real change to occur. The end result for Davanti Nella Gara is a dominant new culture based on respect and humility, highly efficient processes that will deliver a wealth of innovations, sales, and profits for many years to come, and an owner who leaves a bright future for the people and company he's known and loved his entire life.

Davanti Nella Gara, an Italian bicycle company, makes the best racing bikes in the world. But after decades of market dominance, competitors have brought the industry leader back to the Peloton. The company's second-generation owner longs for retirement, but a tired product lineup is pushing down profits and the firm's market value will never support his ride into the sunset. The flawed but beloved owner seeks out the counsel of an old friend and successful businessman, who steers him toward a fast and remarkable transformation, one fueled by a relentless focus on innovation excellence. An engaging business novel, Winning Innovation dives into the art and science of innovation; the thrills of the European bike-racing circuit; the vibrant landscape and cuisine of Italy; and a cast of intriguing characters who work to put Davanti on the road to sustained prosperity. The company's leader isn't afraid to learn and apply new ideas to reenergize his company, and finds he cares more about his employees than he could ever imagine. A young innovator struggles to see a product idea to fruition as well as rise into management - and he falls in love along the way. A newly promoted R&D director brings teamwork and transparency to product development and aligns the entire company around innovation. With the help of a seasoned and persistent change agent, in just a year, Davanti deploys a well-defined and -sequenced transformation - a complete and seamless process that can be replicated and scaled by most companies. The leader engages associates in pursuit of the right vision and strategy, candidly supporting them all as they unleash their creative sparks, work through personality conflicts, and take on real-world challenges faced by companies every day. They learn and apply traditional R&D principles in new ways (e.g., cost of delay, sprints, fail fast, late start) and successfully leverage emerging innovation and change-management principles (e.g., idea-creation events, knowledge management, workplace humility, visual management, lean project management). And an aligned, three-phase innovation process - from idea creation to technology development and product design - provides the innovation infrastructure the company needs for revenue creation and success beyond racing bikes. From a top-heavy organization dominated by power struggles and finger-pointing emerges a new Davanti Nella Gara - a flattened, innovative company with: Clear vision and endorsed goals and strategy Speed, responsiveness, and agility Widespread, successful creativity Collaboration and teamwork Superior risk management Respect for people Unquestionable ethics Changed leadership and associate behaviors Project management excellence Rapid problem-solving and experimentation Not just the story of an R&D transformation, Winning Innovation illustrates a companywide transformation of a magnitude that only superior R&D can make possible. It may well be the first book to chronologically introduce the principles for a complete innovation excellence transformation along with the parallel people transformation that is necessary for real change to occur. The end result for Davanti Nella Gara is a dominant new culture based on respect and humility, highly efficient processes that will deliver a wealth of innovations, sales, and profits for many years to come, and an owner who leaves a bright future for the people and company he's known and loved his entire life.

Can I Teach That? Negotiating Taboo Language and Controversial Topics in the Language Arts Classroom is a collection of stories, strategies, advice, and documents collected for teachers who are using or plan to use materials or implement policies they know may be controversial. It is for any teacher dedicated to engaging their students in the complex, challenging, and rewarding activities of reading and writing, for any teacher committed to speaking honestly with students. For any teacher, period. Because when we decide to work with young people, when we commit to sharing books and ideas that engage their hearts and minds, when we strive to get adolescents to think critically and write honestly, we open ourselves up to suspicion and critique from someone, somewhere, no matter how above reproach we feel our materials and strategies are. Few language arts teachers will experience a full-blown challenge to the content of their curriculum, but many may self-censor or suffer through awkward and challenging conversations with colleagues, administrators, parents, and other members of their community. This book is for those times when teachers are called on to defend and legitimize their use of controversial material in their classroom--material that they know reflects students' reality, even as it makes adults uncomfortable and fearful about their inability to protect children from that very reality.

In 2005, Goodyear s research and development (RandD) engine was not performing up to its full potential. The RandD organization developed high-quality tires, but the projects were not always successful. Goodyear embarked on a major initiative to transform its innovation creation processes by learning, understanding, and applying lean product development principles. Within five years, Goodyear saw its product development cycle times slashed by 70 percent, on-time delivery performance rise close to 100 percent, and throughput improve three-fold all achieved with no increase in the RandD budget.Lean-Driven Innovation: Powering Product Development at The Goodyear Tire and Rubber Company describes in great detail how the Goodyear team was able to achieve such significant improvements. Revealing the ups and downs of this successful transformation, the book shares experiences of how this seismic change was managed, how people were engaged, and how Goodyear dramatically reinvigorated its product development and innovation processes and, in the process, delivered substantial more value to customers and to the company.The book also explains how lean product development helped Goodyear dramatically improve revenue by having every new product available when the market needed it. Presenting wide-ranging perspectives from all levels of leadership, this book is ideal for anyone in RandD daring to take on a lean initiative in RandD or who is struggling with a lean transformation that is not delivering to its full potential. Since the book focuses on universal lean principles, it is as insightful to other manufacturing and nonmanufacturing disciplines in any industry as well.The book presents invaluable insights gained by the author during his 36 years within Goodyear, of which 10 have been directly involved in trying to develop, implement, and sustain lean to achieve the company s business objectives. It distills ideas, prac

Winner of the Garden Media Guild Book Photographer of the Year 2015 'This book will inspire readers to envision what is possible even in the smallest, most improbable spaces'. Publishers Weekly 'Just looking at Marianne's stunning photographs made me want to go outside and start re-thinking my plot....I defy any reader not to find a style they can feel comfortable with in this book, there are plenty of ideas which can be adopted, even for the most difficult location'. Reckless Gardener There is no one way to design a garden. The variations and breadth of possibilities are astonishing but it is the choices of the individual that make the world of gardens so exciting. Creating a garden is part common sense and part instinct but we all need inspiration to help us realize the garden we want. Garden Design: A Book of Ideas is the must-have visual reference for garden owners, architects and designers. With over 600 images by award-winning photographer Marianne Majerus and incisive advice from garden designer and best-selling writer Heidi Howcroft, this book takes the reader from getting the concept right to choosing the perfect finishing touches for your outdoor space. The gardens featured are large and small, urban and rural in a wide range of styles from contemporary to classical to naturalistic. Every aspect of designing a garden is explored, from assessing your plot and soil to choosing a style as your inspiration, selecting the right components (be they hard landscaping, boundaries or plants) and tackling more challenging spaces.

Gardens have never been as important as they are today. The breadth of styles and types is hugely varied. Everything goes, whether inspired by the past or looking towards the future, from traditional vegetable plots to vertical gardens and from nature-filled designs to sleek, modernist creations. Choosing what suits your space can be a daunting prospect and everyone, even the professionals, needs help to realize opportunities and create outdoor spaces in tune with their personal needs and dreams. A garden is what we make it: there is no right or wrong way and each is unique. Richly illustrated by the photos of award-winning photographer Marianne Majerus and with illuminating text by landscape architect Heidi Howcroft, this book shows what is possible for every type of garden, from challenging small spaces to expansive plots. Design tools are explained, planting styles explored, and inspiration is drawn from a wide variety of locations and climates to appeal to garden owners and designers everywhere. The book is not only a companion to Garden Design: A Book of Ideas but is also a valuable style catalogue and sourcebook in its own right, encouraging and inspiring readers to discover their own garden style - be it contemporary or traditional, cottage-style or urban minimalist.

Ageing populations have gradually become a major concern in many industrialised countries over the past fifty years, drawing the attention of both politics and science. The target of a raft of health and social policies, older people are often identified as a specific, and vulnerable, population. At the same time, ageing has become a specialisation in many disciplines - medicine, sociology, psychology, to name but three - and a discipline of its own: gerontology. This book questions the framing of old age by focusing on the relationships between policy making and the production of knowledge. The first part explores how the meeting of scientific expertise and the politics of old age anchors the construction of both individual and collective relationships to the future. Part II brings to light the many ways in which issues relating to ageing can be instrumentalised and ideologised in several public debate arenas. Part III argues that scientific knowledge itself composes with objectivity, bringing ideologies of its own to the table, and looks at how this impacts discourse about ageing. In the final part, the contributors discuss how the frames can themselves be experienced at different levels of the division of labour, whether it is by people who work on them (legislators or scientists), by people working with them (professional carers) or by older people themselves. Unpacking the political and moral dimensions of scientific research on ageing, this cutting-edge volume brings together a range of multidisciplinary, European perspectives, and will be of use to all those interested in old age and the social sciences.

Melanism: Evolution in Action describes investigations into a ubiquitous biological phenomenon, the existence of dark, or melanic, forms of many species of mammals, insects, and some plants. Melanism is a particularly exciting phenomenon in terms of our understanding of evolution. Unlike many other polymorphisms, the rise of a melanic population within a species is a visible alteration. Not only this, but melanism may sometimes occur dramatically quickly compared to other evolutionary change. Examples of melanism include one of the most famous illustrations of Darwinian natural selection, the peppered moth. This book, the first written on melanism since 1973, gives a lucid and up-to-date appraisal of the subject. The book is divided into ten chapters. The first four chapters place melanism into its historical and scientific context, with illustrations of its occurrence, and physical and genetic properties. Chapters 5-9 look in more detail at melanism in moths and ladybirds, explaining the diversity of evolutionary reasons for melanism, and the complexities underlying this apparently simple phenomenon. The final chapter shows how the study of melanism has contibuted to our understanding of biological evolution as a whole. Written in an engaging and readable style, by an author whose enthusiasm and depth of knowledge is apparent throughout, this book will be welcomed by all students and researchers in the fields of evolution, ecology, entomology, and genetics. It will also be of relevance to professional and amateur entomologists and lepidopterists alike.

In the past, our ideas of psychiatric hospitals and their history have been shaped by objects like straitjackets, cribs, and binding belts. These powerful objects were often used as a synonym for psychiatry and the way psychiatric patients were treated, yet very little is known about the agency of these objects and their appropriation by staff and patients. By focusing on material cultures, this book offers a new perspective on the history of psychiatry: it enables a narrative in which practicing psychiatry is part of a complex entanglement in which power is constantly negotiated. Scholars from different academic disciplines show how this material-based approach opens up new perspectives on the agency and imagination of men and women inside psychiatry.

A beautifully illustrated history of the world famous landscape garden at Stourhead, created by generations of the Hoare banking dynasty. Cross the south lawn at Stourhead and descend through the ancient and rare trees. Soon you will see a great lake appear, decorated with classical temples and arched bridge that lunges to the other side of the water. Continue on and you will find a mystical, jagged grotto; a gothic hideaway; gods, muses and saints. This is how Henry Hoare - known as Henry the Magnificent - would have approached the garden he designed with Henry Flitcroft. Did he imagine himself as a journeying Aeneas, or was he recreating a Claud Lorrain landscape? This is the first history - in colour - of a unique landscape created by generations of the Hoare banking family. It follows its evolution, describing how flights of folly, individual flair and tastes, combined with careful stewardship, have formed a national treasure and one of the finest example of the English landscape garden. The book includes a foreword by James Stourton and newly commissioned photography by renowned garden photographer Marianne Majerus.

In 2005, Goodyear's research and development (R&D) engine was not performing up to its full potential. The R&D organization developed high-quality tires, but the projects were not always successful. Goodyear embarked on a major initiative to transform its innovation creation processes by learning, understanding, and applying lean product development principles. Within five years, Goodyear saw its product development cycle times slashed by 70 percent, on-time delivery performance rise close to 100 percent, and throughput improve three-fold - all achieved with no increase in the R&D budget. Lean-Driven Innovation: Powering Product Development at The Goodyear Tire & Rubber Company describes in great detail how the Goodyear team was able to achieve such significant improvements. Revealing the ups and downs of this successful transformation, the book shares experiences of how this seismic change was managed, how people were engaged, and how Goodyear dramatically reinvigorated its product development and innovation processes-and, in the process, delivered substantial more value to customers and to the company. The book also explains how lean product development helped Goodyear dramatically improve revenue by having every new product available when the market needed it. Presenting wide-ranging perspectives from all levels of leadership, this book is ideal for anyone in R&D daring to take on a lean initiative in R&D or who is struggling with a lean transformation that is not delivering to its full potential. Since the book focuses on universal lean principles, it is as insightful to other manufacturing and nonmanufacturing disciplines in any industry as well. The book presents invaluable insights gained by the author during his 36 years within Goodyear, of which 10 have been directly involved in trying to develop, implement, and sustain lean to achieve the company's business objectives. It distills ideas, practices, failures, and successes into key principles that lean product development practitioners can easily implement. After reading this book, you will gain a practical path for applying lean to the innovation processes of your organization, including where to begin and what to do, regardless of the industry and the status of your transformation. Watch Norbert Majerus discuss Lean-Driven Innovation at: https://youtu.be/yIlJEMJIcyA

Essay from the year 2013 in the subject Politics - International Politics - Region: USA, grade: 1,7, University of Leicester, language: English, abstract: When in May 2011 American TV networks first announced the killing of Al-Qaeda leader Osama Bin Laden, the nation-wide scenes of publicly expressed joy and relief witnessed thereafter may have seemed to some strikingly reminiscent of that other memorable day in mid-August 1945 when American citizens could at long last celebrate victory over the Japanese Empire in World War II. However, one might argue, is it possible that popular jubilation over Bin Laden's death might ultimately not also have reflected some kind of premature or even false belief in Al-Qaeda's simultaneous and permanent demise as a functioning terrorist organization as well?