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Synthesis and Characterization of Glycosides (Hardcover, 3rd ed. 2022): Marco Brito-arias Synthesis and Characterization of Glycosides (Hardcover, 3rd ed. 2022)
Marco Brito-arias
R4,333 Discovery Miles 43 330 Ships in 18 - 22 working days

This third edition is a comprehensive and extended study about the best known approaches for preparing the main types of glycosides, covering the classic and more recent glycosylation reactions used for preparing simple and challenging glycosides currently used as potent antiviral and antineoplastic drugs, or fluorogenic substrates used for enzymatic detection in cell biology. Besides, this new edition provides more examples of the glycosidic methodologies followed for preparing complex glycoconjugates such as glycoproteins and glycosphingolipids and gangliosides used as adjuvants or as synthetic vaccines candidates. Also, additional mechanistic evidence is presented for better understanding of the glycosylation reaction, trying to identify the variables mainly depending on protecting and leaving groups, as well as catalyst and reaction condition which altogether directs the anomeric stereo control. A chapter on the glycoside hydrolysis is included in view of the increasing interest in the use of biomass as a natural and renewable source for obtaining important intermediates or products used in food or valuable materials. The author includes information in the characterization of glycosides section with the aim of giving additional tools for the structural assignment through NMR, X-Ray and mass spectra techniques.

Synthesis and Characterization of Glycosides (3rd ed. 2022): Marco Brito-arias Synthesis and Characterization of Glycosides (3rd ed. 2022)
Marco Brito-arias
R3,174 Discovery Miles 31 740 Ships in 18 - 22 working days

This third edition is a comprehensive and extended study about the best known approaches for preparing the main types of glycosides, covering the classic and more recent glycosylation reactions used for preparing simple and challenging glycosides currently used as potent antiviral and antineoplastic drugs, or fluorogenic substrates used for enzymatic detection in cell biology.  Besides, this new edition provides more examples of the glycosidic methodologies followed for preparing complex glycoconjugates such as glycoproteins and glycosphingolipids and gangliosides used as adjuvants or as synthetic vaccines candidates. Also, additional mechanistic evidence is presented for better understanding of the glycosylation reaction, trying to identify the variables mainly depending on protecting and leaving groups, as well as catalyst and reaction condition which altogether directs the anomeric stereo control. A chapter on the glycoside hydrolysis is included in view of the increasing interest in the use of biomass as a natural and renewable source for obtaining important intermediates or products used in food or valuable materials. The author includes information in the characterization of glycosides section with the aim of giving additional tools for the structural assignment through NMR, X-Ray and mass spectra techniques.

Synthesis and Characterization of Glycosides (Paperback, Softcover reprint of the original 2nd ed. 2016): Marco Brito-arias Synthesis and Characterization of Glycosides (Paperback, Softcover reprint of the original 2nd ed. 2016)
Marco Brito-arias
R5,127 Discovery Miles 51 270 Ships in 18 - 22 working days

This second edition is a short and comprehensive study on the best known approaches for preparing the main types of glycosides. It covers synthetic pathways of challenging glycosides known as antiviral or antineoplastic drugs, and synthetic substrates used for enzymatic detection, including those used for detection of gene markers in plant biotechnology. The author pays special attention to the structural characterization of glycosides and provides the basic tools for the structural assignment through NMR, X-Ray and mass spectra techniques. The book also covers strategies for preparation of antiviral and antineoplastic drugs included in a drug design course.

Enzymes Involved in Glycolysis, Fatty Acid and Amino Acid Biosynthesis - Active Site Mechanisms and Inhibition (Paperback):... Enzymes Involved in Glycolysis, Fatty Acid and Amino Acid Biosynthesis - Active Site Mechanisms and Inhibition (Paperback)
Marco Brito-arias
R2,018 Discovery Miles 20 180 Ships in 18 - 22 working days
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