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Synthesis and Characterization of Glycosides (Hardcover, 3rd ed. 2022)
Loot Price: R4,404
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Synthesis and Characterization of Glycosides (Hardcover, 3rd ed. 2022)
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This third edition is a comprehensive and extended study about the
best known approaches for preparing the main types of glycosides,
covering the classic and more recent glycosylation reactions used
for preparing simple and challenging glycosides currently used as
potent antiviral and antineoplastic drugs, or fluorogenic
substrates used for enzymatic detection in cell biology. Besides,
this new edition provides more examples of the glycosidic
methodologies followed for preparing complex glycoconjugates such
as glycoproteins and glycosphingolipids and gangliosides used as
adjuvants or as synthetic vaccines candidates. Also, additional
mechanistic evidence is presented for better understanding of the
glycosylation reaction, trying to identify the variables mainly
depending on protecting and leaving groups, as well as catalyst and
reaction condition which altogether directs the anomeric stereo
control. A chapter on the glycoside hydrolysis is included in view
of the increasing interest in the use of biomass as a natural and
renewable source for obtaining important intermediates or products
used in food or valuable materials. The author includes information
in the characterization of glycosides section with the aim of
giving additional tools for the structural assignment through NMR,
X-Ray and mass spectra techniques.
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