This text focuses on various factors associated with orphan diseases and the influence and role of health information technologies. Orphan diseases have not been adopted by the pharmaceutical industry because they provide little financial incentive to treat or prevent it. It is estimated that 6,000-7,000 orphan diseases exist today; as medical knowledge continues to expand, this number is likely to become much greater. The book highlights the opportunities and challenges in this increasingly important area. The book explores new avenues which are opened by information technologies and Health 2.0, and highlights also economic opportunities of orphan disease medicine. The editors of this new book have international experience and competencies in the key areas of patient empowerment, healthcare and clinical knowledge management, healthcare inequalities and disparities, rare diseases and patient advocacy.

It is a tragic paradox of American health care: a system renowned for world-class doctors, the latest medical technologies, and miraculous treatments has shocking inadequacies when it comes to the health of the urban poor. Urban Health Knowledge Management outlines bold, workable strategies for addressing this disparity and eliminating the "knowledge islands" that so often disrupt effective service delivery. The book offers a wide-reaching global framework for organizational competence leading to improved care quality and outcomes for traditionally underserved clients in diverse, challenging settings. Its contributors understand the issues fluently, imparting both macro and micro concepts of KM with clear rationales and real-world examples as they: * Analyze key aspects of KM and explains their applicability to urban health. * Introduce the KM tools and technologies most relevant to health care delivery. * Offer evidence of the role of KM in improving clinical efficacy and executive decision-making. * Provide extended case examples of KM-based programs used in Washington, D.C. (child health), South Africa (HIV/AIDS), and Australia (health inequities). * Apply KM principles to urban health needs in developing countries. * Discuss new approaches to managing, evaluating, and improving delivery systems in the book's "Measures and Metrics" section. Urban health professionals, as well as health care executives and administrators, will find Urban Health Knowledge Management a significant resource for bringing service delivery up to speed at a time of great advancement and change.

Paralleling emerging trends in cyber-health technology, concerns are mounting about racial and ethnic disparities in health care utilization and outcomes. This book brings these themes together, challenging readers to use, promote, and develop new technology-based methods for closing these gaps. Edited by a leading urban health advocate and featuring 16 expert contributors, the book examines cyber-strategies with the greatest potential toward effective, equitable care, improved service delivery and better health outcomes for all. The rise of e-Patients and the transformation of the doctor-patient relationship are also discussed.

This volume critically examines the role of science in the humanities and social sciences. It studies how cultures and societies in South Asia and Europe underwent a transformation with the adoption or adaptation of scientific methods, turning ancient cultural processes and phenomena into an enhanced scientific structure. The chapters in this book Discuss the development of science as a method in modern and historical contexts and the differences between modern science, scientification and pseudoscience. Study the interactions between bodies of knowledge such as Sanskrit and computer science; mathematics and Vedic mathematics; science and philosophy. Drawing on textual material, extensive fieldwork and in-depth interviews, this book will be of great interest to scholars and researchers of philosophy, Indology, history, linguistics, history and philosophy of science and social science.

Short Stories and Political Philosophy: Power, Prose, and Persuasion explores the relationship between fictional short stories and the classic works of political philosophy. This edited volume addresses the innovative ways that short stories grapple with the same complex political and moral questions, concerns, and problems studied in the fields of political philosophy and ethics. The volume is designed to highlight the ways in which short stories may be used as an access point for the challenging works of political philosophy encountered in higher education. Each chapter analyzes a single story through the lens of thinkers ranging from Plato and Aristotle to Max Weber and Hannah Arendt. The contributors to this volume do not adhere to a single theme or intellectual tradition. Rather, this volume is a celebration of the intellectual and literary diversity available to students and teachers of political philosophy. It is a resource for scholars as well as educators who seek to incorporate short stories into their teaching practice.

The core of this edited volume originates from a special issue of the Journal of the Ottoman and Turkish Studies Association (JOTSA) that goes well beyond the special issue to incorporate the stimulating discussions and insights of two Middle East Studies Association conference roundtables and the important work of additional scholars in order to create a state-of-the-field volume on Ottoman sociolegal studies, particularly regarding Ottoman international law from the eighteenth century to the end of the empire. It makes several important contributions to Ottoman and Turkish studies, namely, by introducing these disciplines to the broader fields of trans-imperial studies, comparative international law, and legal history. Combining the best practices of diplomatic history and history from below to integrate the Ottoman Empire and its subjects into the broader debates of the nineteenth-century trans-imperial history this unique volume represents the exciting work and cutting-edge scholarship on these topics that will continue to shape the field in years to come.

This volume critically examines the role of science in the humanities and social sciences. It studies how cultures and societies in South Asia and Europe underwent a transformation with the adoption or adaptation of scientific methods, turning ancient cultural processes and phenomena into an enhanced scientific structure. The chapters in this book Discuss the development of science as a method in modern and historical contexts and the differences between modern science, scientification and pseudoscience. Study the interactions between bodies of knowledge such as Sanskrit and computer science; mathematics and Vedic mathematics; science and philosophy. Drawing on textual material, extensive fieldwork and in-depth interviews, this book will be of great interest to scholars and researchers of philosophy, Indology, history, linguistics, history and philosophy of science and social science.

While there have been tremendous advances in our scientific understanding of the brain, this work has been largely academic, and often oriented toward clinical publication. Cognitive Neuroscience of Human Systems: Work and Everyday Life addresses the relationship between neurophysiological processes and the performance and experience of humans in everyday life. It samples the vast neuroscience literature to identify those areas of research that speak directly to the performance and experience of humans in everyday settings, highlighting the practical, everyday application of brain science. The book explains the underlying basis for well-established principles from human factors, ergonomics, and industrial engineering and design. It also sheds new light on factors affecting human performance and behavior. This is not an academic treatment of neuroscience, but rather a translation that makes modern brain science accessible and easily applicable to systems design, education and training, and the development of policies and practices. The authors supply clear and direct guidance on the applications of principles from brain science to everyday problems. With discussions of topics from brain science and their relevance to everyday activities, the book focuses on the science, describing the findings and the studies producing these findings. It then decodes how these findings relate to everyday life and how you can integrate them into your work to achieve more effective outcomes based on a fundamental understanding of how the operations of the human brain produce behavior and modulate performance.

This fascinating volume offers a transdisciplinary and transcultural approach to understanding the senses by exploring themes in anthropologies of sound, sight, smell, taste, touch, and movement as expressed through aesthetic, perceptual, religious, and spiritual experiences. In drawing upon comparative perspectives from Indian and Western theories, the essays demonstrate the integral relation of senses with each other as well as with allied notions of the body, emotion and cultural memory. Stressing the continued relevance of senses as they manifest in a globalized world under the influence of new media, this work will interest scholars of anthropology, cultural studies, sociology, ritual studies, psychology, religion, philosophy, and history.

This fascinating volume offers a transdisciplinary and transcultural approach to understanding the senses by exploring themes in anthropologies of sound, sight, smell, taste, touch, and movement as expressed through aesthetic, perceptual, religious, and spiritual experiences. In drawing upon comparative perspectives from Indian and Western theories, the essays demonstrate the integral relation of senses with each other as well as with allied notions of the body, emotion and cultural memory. Stressing the continued relevance of senses as they manifest in a globalized world under the influence of new media, this work will interest scholars of anthropology, cultural studies, sociology, ritual studies, psychology, religion, philosophy, and history.

This intriguing book engages with the concept of the body in its cultural context by acknowledging and demonstrating that the human body is understood differently in Western and Indian cultures. The contributors go on to show that any attempt to put forward a single concept of the body within Indian culture would be misleading.

Divided into three parts, the book examines the considerable and often conflicting variations in body images and body concepts. In Part One the contributors focus on the representation of the body in religious and philosophical texts; representations that emerged from reading, translating and interpreting classical writings from diverse historical and anthropological approaches. Through predominantly ethnographic studies, Part Two explores the role of the body in narratives and ritual performance, from dance to ritualistic ceremonies. Visualisation processes of the body are examined in Part Three, focusing on developments in modern and contemporary periods: from visual practices at the Mughal court, to the multiple bodies of the bride, and the influence of new media.

This volume is a fascinating collection of articles for those in the fields of sociology and anthropology, history, religion, cultural studies and South Asian studies.

Challenging the idea that rituals are static and emotions irrational, the volume explores the manifold qualities of emotions in ritual practices. Focusing explicitly on the relationship between emotions and rituals, it poses two central questions. First, how and to what extent do emotions shape rituals? Second, in what way are emotions ritualized in and beyond rituals? Strong emotions are generally considered to be more spontaneous and uncontrolled, whereas ritual behaviour is regarded as planned, formalized and stereotyped, and hence less emotional. However, as the volume demonstrates, rituals often reveal strong emotions among participants, are motivated by feelings, or are intended to generate them. The essays discuss the motivation for rituals; the healing function of emotions; the creation of new emotions through new media; the aspect of mimesis in the generation of feelings; individual, collective, and non-human emotions; the importance of trance and possession; staged emotions and emotions on stage; emotions in the context of martyrdom; emotions in Indian and Western dance traditions; emotions of love, sorrow, fear, aggression, and devotion. Furthermore, aesthetic and sensory dimensions, as well as emic concepts, of emotions in rituals are underscored as relevant in understanding social practice.

Challenging the idea that rituals are static and emotions irrational, the volume explores the manifold qualities of emotions in ritual practices. Focusing explicitly on the relationship between emotions and rituals, it poses two central questions. First, how and to what extent do emotions shape rituals? Second, in what way are emotions ritualized in and beyond rituals? Strong emotions are generally considered to be more spontaneous and uncontrolled, whereas ritual behaviour is regarded as planned, formalized and stereotyped, and hence less emotional. However, as the volume demonstrates, rituals often reveal strong emotions among participants, are motivated by feelings, or are intended to generate them. The essays discuss the motivation for rituals; the healing function of emotions; the creation of new emotions through new media; the aspect of mimesis in the generation of feelings; individual, collective, and non-human emotions; the importance of trance and possession; staged emotions and emotions on stage; emotions in the context of martyrdom; emotions in Indian and Western dance traditions; emotions of love, sorrow, fear, aggression, and devotion. Furthermore, aesthetic and sensory dimensions, as well as emic concepts, of emotions in rituals are underscored as relevant in understanding social practice.

Digital Homecare is a collection of services to deliver, maintain and improve care in the home environment using the latest ICT technology and devices.

It is important to recognize the wide range of issues that are covered by digital homecare. This book shows a good selection of related issues, be it experience, technologies, managerial issues or standardization.

A very diverse "audience"; elderly, people with chronic conditions, disabled, to name the most important groups, benefits from digital homecare, within the comfort and protection of their own homes.

While there have been tremendous advances in our scientific understanding of the brain, this work has been largely academic, and often oriented toward clinical publication. Cognitive Neuroscience of Human Systems: Work and Everyday Life addresses the relationship between neurophysiological processes and the performance and experience of humans in everyday life. It samples the vast neuroscience literature to identify those areas of research that speak directly to the performance and experience of humans in everyday settings, highlighting the practical, everyday application of brain science. The book explains the underlying basis for well-established principles from human factors, ergonomics, and industrial engineering and design. It also sheds new light on factors affecting human performance and behavior. This is not an academic treatment of neuroscience, but rather a translation that makes modern brain science accessible and easily applicable to systems design, education and training, and the development of policies and practices. The authors supply clear and direct guidance on the applications of principles from brain science to everyday problems. With discussions of topics from brain science and their relevance to everyday activities, the book focuses on the science, describing the findings and the studies producing these findings. It then decodes how these findings relate to everyday life and how you can integrate them into your work to achieve more effective outcomes based on a fundamental understanding of how the operations of the human brain produce behavior and modulate performance.

With the advent of the steamship, repeated outbreaks of cholera marked oceanic pilgrimages to Mecca as a dangerous form of travel and a vehicle for the globalization of epidemic diseases. European, especially British Indian, officials also feared that lengthy sojourns in Arabia might expose their Muslim subjects to radicalizing influences from anticolonial dissidents and pan-Islamic activists. European colonial empires’ newfound ability to set the terms of hajj travel not only affected the lives of millions of pilgrims but also dramatically challenged the Ottoman Empire, the world’s only remaining Muslim imperial power. Michael Christopher Low analyzes the late Ottoman hajj and Hijaz region as transimperial spaces, reshaped by the competing forces of Istanbul’s project of frontier modernization and the extraterritorial reach of British India’s steamship empire in the Indian Ocean and Red Sea. Imperial Mecca recasts Ottoman Arabia as a distant, unstable semiautonomous frontier that Istanbul struggled to modernize and defend against the onslaught of colonial steamship mobility. As it turned out, steamships carried not just pilgrims, passports, and microbes, but the specter of legal imperialism and colonial intervention. Over the course of roughly a half century from the 1850s through World War I, British India’s fear of the hajj as a vector of anticolonial subversion gradually gave way to an increasingly sophisticated administrative, legal, and medical protectorate over the steamship hajj, threatening to eclipse the Ottoman state and Caliphate’s prized legitimizing claim as protector of Islam’s most holy places. Drawing on a wide range of Ottoman and British archival sources, this book sheds new light on the transimperial and global histories traversed along the pilgrimage to Mecca.

This text focuses on various factors associated with orphan diseases and the influence and role of health information technologies. Orphan diseases have not been adopted by the pharmaceutical industry because they provide little financial incentive to treat or prevent it. It is estimated that 6,000-7,000 orphan diseases exist today; as medical knowledge continues to expand, this number is likely to become much greater. The book highlights the opportunities and challenges in this increasingly important area. The book explores new avenues which are opened by information technologies and Health 2.0, and highlights also economic opportunities of orphan disease medicine. The editors of this new book have international experience and competencies in the key areas of patient empowerment, healthcare and clinical knowledge management, healthcare inequalities and disparities, rare diseases and patient advocacy.

Digital Homecare is a collection of services to deliver, maintain and improve care in the home environment using the latest ICT technology and devices. It is important to recognize the wide range of issues that are covered by digital homecare. This book shows a good selection of related issues, be it experience, technologies, managerial issues or standardization. A very diverse "audience"; elderly, people with chronic conditions, disabled, to name the most important groups, benefits from digital homecare, within the comfort and protection of their own homes.

Paralleling emerging trends in cyber-health technology, concerns are mounting about racial, ethnic, disparities in health care utilization and outcomes. eHealth Solutions for Health Care Disparities brings these currents together, challenging readers to use, promote, and develop new technology-based methods for closing these gaps. Edited by a leading urban health advocate and featuring 16 expert contributors, the book examines cyber-strategies with the greatest potential toward effective, equitable care, improved service delivery and better health outcomes for all.

Chapters go well beyond the possibilities of the Electronic Medical Record to discuss emerging roles for information technology in promoting healthful behavior changes (e.g., nutrition, weight loss, smoking cessation), disease prevention (e.g., cancer, HIV), and healthcare utilization, patient education and medicine compliance). The rise of e-Patients and the transformation of the doctor-patient relationship are also discussed. Opportunities for Web based products and interventions are explored in terms of tracking disparities, improving healthcare utilization and health outcomes, reducing disparities and monitoring trends among patients, whether they have Internet capabilities or not.

This intriguing book engages with the concept of the body in its cultural context by acknowledging and demonstrating that the human body is understood differently in Western and Indian cultures. The contributors go on to show that any attempt to put forward a single concept of the body within Indian culture would be misleading. Divided into three parts, the book examines the considerable and often conflicting variations in body images and body concepts. In Part One the contributors focus on the representation of the body in religious and philosophical texts; representations that emerged from reading, translating and interpreting classical writings from diverse historical and anthropological approaches. Through predominantly ethnographic studies, Part Two explores the role of the body in narratives and ritual performance, from dance to ritualistic ceremonies. Visualisation processes of the body are examined in Part Three, focusing on developments in modern and contemporary periods: from visual practices at the Mughal court, to the multiple bodies of the bride, and the influence of new media. This volume is a fascinating collection of articles for those in the fields of sociology and anthropology, history, religion, cultural studies and South Asian studies.

The preeminent synth-pop outfit for four decades, Depeche Mode have endured an ever-shifting musical landscape, rising above fads and battles with personal demons, somehow managing to retain a hold on the charts and the audience, the latter which continues to grow as new generations discover them and become “devotees.”

Depeche Mode FAQ: All That's Left to Know About the World's Finest Synth-Pop Band shows how a group of schoolmates influenced by the likes of Kraftwerk, Joy Division, and mid-period David Bowie carved out their own musical niche until they became one of the most influential bands to come out of England. Depeche Mode were Europe’s best-kept secret in the early '80s with the albums Construction Time Again and the—perhaps—tongue-in-cheek-titled Music for the Masses. They became a worldwide phenomenon as the '90s dawned, with the landmark LP Violator, containing the smash hits "Personal Jesus," "Enjoy the Silence," and "Policy of Truth."

But success came at a price as depression, alcoholism, drug addiction, and personnel departures threatened to derail the band. It wasn’t a question of whether the music of Depeche Mode would be able to withstand fickle industry changes, but rather if the members of the group themselves could make it out alive. Depeche Mode FAQ shows how they did, becoming legends in the process.

With the advent of the steamship, repeated outbreaks of cholera marked oceanic pilgrimages to Mecca as a dangerous form of travel and a vehicle for the globalization of epidemic diseases. European, especially British Indian, officials also feared that lengthy sojourns in Arabia might expose their Muslim subjects to radicalizing influences from anticolonial dissidents and pan-Islamic activists. European colonial empires’ newfound ability to set the terms of hajj travel not only affected the lives of millions of pilgrims but also dramatically challenged the Ottoman Empire, the world’s only remaining Muslim imperial power. Michael Christopher Low analyzes the late Ottoman hajj and Hijaz region as transimperial spaces, reshaped by the competing forces of Istanbul’s project of frontier modernization and the extraterritorial reach of British India’s steamship empire in the Indian Ocean and Red Sea. Imperial Mecca recasts Ottoman Arabia as a distant, unstable semiautonomous frontier that Istanbul struggled to modernize and defend against the onslaught of colonial steamship mobility. As it turned out, steamships carried not just pilgrims, passports, and microbes, but the specter of legal imperialism and colonial intervention. Over the course of roughly a half century from the 1850s through World War I, British India’s fear of the hajj as a vector of anticolonial subversion gradually gave way to an increasingly sophisticated administrative, legal, and medical protectorate over the steamship hajj, threatening to eclipse the Ottoman state and Caliphate’s prized legitimizing claim as protector of Islam’s most holy places. Drawing on a wide range of Ottoman and British archival sources, this book sheds new light on the transimperial and global histories traversed along the pilgrimage to Mecca.

This open access book covers aspects of unsupervised machine learning used for knowledge discovery in data science and introduces a data-driven approach to cluster analysis, the Databionic swarm (DBS). DBS consists of the 3D landscape visualization and clustering of data. The 3D landscape enables 3D printing of high-dimensional data structures. The clustering and number of clusters or an absence of cluster structure are verified by the 3D landscape at a glance. DBS is the first swarm-based technique that shows emergent properties while exploiting concepts of swarm intelligence, self-organization and the Nash equilibrium concept from game theory. It results in the elimination of a global objective function and the setting of parameters. By downloading the R package DBS can be applied to data drawn from diverse research fields and used even by non-professionals in the field of data mining.