Meems and Feefs are ferrets from the planet Ferretonia. When they secretly carry out an experiment using Ferretonia's forbidden Ancient Tech, it all goes wrong, and they end up crash-landing on Earth! Meems is a smart, cheeky, and tech-savvy ferret from the planet Ferretonia. Feefs is his goofy, happy-go-lucky brother. Unsatisfied and bored with their quiet life on Ferretonia, the brothers build a forbidden Travel Opal to go on adventure but accidentally bite off more than they can chew and get stuck on planet Earth with no way to get home. The ferrets journey to an animal shelter where they meet a shy teen named Liza. After using a Communication Opal on Liza to transcend language barriers, Meems and Feefs put their trust in her and embark on a race-against-time adventure, or else they're doomed to stay on Earth forever! This laugh-out-loud and heartwarming graphic novel is perfect for readers 8+ and ferret fans of all ages.

Meems and Feefs are ferrets from the planet Ferretonia. When they secretly carry out an experiment using Ferretonia's forbidden Ancient Tech, it all goes wrong, and they end up crash-landing on Earth! Meems is a smart, cheeky, and tech-savvy ferret from the planet Ferretonia. Feefs is his goofy, happy-go-lucky brother. Unsatisfied and bored with their quiet life on Ferretonia, the brothers build a forbidden Travel Opal to go on adventure but accidentally bite off more than they can chew and get stuck on planet Earth with no way to get home. The ferrets journey to an animal shelter where they meet a shy teen named Liza. After using a Communication Opal on Liza to transcend language barriers, Meems and Feefs put their trust in her and embark on a race-against-time adventure, or else they're doomed to stay on Earth forever! This laugh-out-loud and heartwarming graphic novel is perfect for readers 8+ and ferret fans of all ages.

Neurofibromatosis type 1 (NF1), caused by mutational inactivation of the "NF1" tumour suppressor gene, is one of the most common dominantly inherited human disorders, affecting 1 in 3000 individuals worldwide. This book presents in concise fashion, but as comprehensively as possible, our current state of knowledge on the molecular genetics, molecular biology and cellular biology of this tumour predisposition syndrome.

Written by internationally recognized experts in the field, the 44 chapters that constitute this edited volume provide the reader with a broad overview of the clinical features of the disease, the structure and expression of the "NF1" gene, its germ line and somatic mutational spectra and genotype-phenotype relationships, the structure and function of its protein product (neurofibromin), NF1 modifying loci, the molecular pathology of NF1-associated tumours, animal models of the disease, psycho-social aspects and future prospects for therapeutic treatment.

This book examines the role of race in athletic programs in the United States. Intercollegiate athletics remains a contested terrain where race and racism are critical issues often absent in the public discourse. Recently, the economic motives of intercollegiate athletic programs and academic indiscretions have unveiled behaviors that stand to tarnish the images of institutions of higher education and reinforce racial stereotypes about the intellectual inabilities of Black males. Through the lens of Critical Race Theory (CRT), this volume analyzes sport as the platform that reflects and reinforces ideas about race within American culture, as well as the platform where resistance is forged against dominant racial ideologies.

The book provides critical perspectives that reach beyond the technical approaches of international financial institutions and proponents of the liberal peace formula. It investigates political economies characterized by the legacies of disruption to production and exchange, by population displacement, poverty, and by 'criminality'.

What you really need to know, but no-one told you. The best-selling Essential Guide to Acute Care contains everything you need to know about acute care that you can't find in a standard textbook. The third edition has been extensively revised and updated, presenting new oxygen guidelines, updated evidence and practice around sepsis, fluid balance and volume resuscitation, acute kidney injury, perioperative care, and much more. The third edition retains the accessible style and comprehensive coverage that has made Essential Guide to Acute Care essential reading for those who look after acutely ill adults. Throughout the book, 'mini-tutorials' expand on the latest thinking or controversies, and there are practical case histories to reinforce learning at the end of each chapter. The chapters are designed to be read by individuals or used for teaching material in tutorials. This new edition of Essential Guide to Acute Care Provides up-to-date and practical guidance on the principles of acute care, written by experienced teachers and clinicians Offers a unique approach to the subject that focuses on understanding rather than lists and 'recipes' Explains the altered physiology that accompanies acute illness in adults Includes learning objectives, self-assessment questions, and illustrative examples related to clinical practice Essential Guide to Acute Care is an indispensable volume for medical students and newly graduated doctors; doctors training in medicine, surgery, anaesthesia and emergency medicine; advanced clinical practitioners; nurses and allied health professionals working in acute and critical care; and teachers.

ABC of Clinical Reasoning Being a good clinician is not only about knowledge -- how doctors and other healthcare professionals think, reason, and make decisions is arguably their most critical skill. The second edition of the ABC of Clinical Reasoning breaks down clinical reasoning into its core components and explores each of these in more detail, including the applications for clinical practice, teaching, and learning. Informed by the latest evidence from cognitive psychology, education, and studies of expertise, this edition has been extensively re-written and updated, and covers: Key components of clinical reasoning: evidence-based history and examination, choosing and interpreting diagnostic tests, problem identification and management, and shared decision-making Key concepts in clinical reasoning, such dual process theories, and script theory Situativity and human factors Metacognition and cognitive strategies Teaching clinical reasoning From a team of expert authors, the ABC of Clinical Reasoning is essential reading for all students, clinical teachers, curriculum planners and clinicians involved in diagnosis. About the ABC series The ABC series has been designed to help you access information quickly and deliver the best patient care, and remains an essential reference tool for GPs, junior doctors, medical students and healthcare professionals. Now offering over 80 titles, this extensive series provides you with a quick and dependable reference on a range of topics in all the major specialties. The ABC series is the essential and dependable source of up-to-date information for all practitioners and students in primary healthcare. To receive automatic updates on books and journals in your specialty, join our email list. Sign up today at www.wiley.com/email

In recent years, there has been increased attention garnered toward activism in sport within the United States. In 2016, Colin Kaepernick's activist act of taking a knee during the national anthem before National Football League games sparked a nationwide debate on the intersection of sports, race, and politics. Kaepernick's actions were a part of a long lineage of activism in and through sport. Prior accounts of African American activism in and through sport have been limited in the following eight areas: (1) primarily focused on one type of activism (e.g., symbolic protests/boycotts); (2) a lack of differentiation between activism and borderline activist actions (e.g., agency, pioneering, and advocacy); (3) a lack of emphasis on hybrid resistance; (4) a focus on athletes and teams versus sportspersons (i.e., media, scholars, business leaders, and community members) and institutions (i.e., historically Black colleges and universities, athletic programs, and conferences) more broadly; (5) largely focused on one era of prominent athlete activism in the 1960s; (6) principally excluded and marginalized the importance of women's role in resistance efforts (e.g., activism for social change); (7) primarily focused on activism at the intercollegiate and professional levels with less attention toward youth and interscholastic levels; and (8) a lack of theoretically driven analyses of the resistance efforts exhibited by African American sportspersons, teams, groups, organizations, and institutions. Instead of exclusively using the term activism, the author uses the broader encompassing term of resistance as the focal framework for this text. Resistance is defined as intentional and/or unintentional actions by individuals, groups, organizations, and/or institutions that challenge oppressive systems and ideological hegemony. Using adaptive race- and ethnicity-centric typologies and interdisciplinary theories, this book offers a critical analysis of African Americans' intra- and inter-generational resistance actions where, when, why, and how sport has been utilized to express their humanity, preserve their cultural heritages, empower themselves and their communities, project political views, and pursue freedom, equality, and justice.

Lung cancer is the leading cause of cancer mortality in Western countries. It also provides an archetypal example of how inherited predisposing genetic variants may interact with an environmental influence (smoking) to modulate individual cancer risk.

The Molecular Genetics of Lung Cancer describes how the new techniques, methods and approaches of molecular genetics are being used to unravel the complexities of the mechanisms underlying lung tumorigenesis by analysis at the DNA, RNA and protein levels with potentially important implications for tumour classification, diagnosis, prognosis and treatment as well as providing new insights into how lung tumours arise and how they progress to malignancy.

Previous critics have documented the damaging effects of the current exploitative sporting and education structures in the United States on Black males and the broader Black community. However, largely missing from scholarly literature and popular discourses on this topic is a comprehensive analysis of the heterogeneity among Black male athletes' lived experiences and outcomes over their lifespans. From Exploitation Back to Empowerment: Black Male Holistic (Under)Development Through Sport and (Mis)Education by Joseph N. Cooper addresses three major issues: (1) the under theorization of Black male athletes' socialization processes, (2) the preponderance of deficit-based theories on Black male athletes, and (3) the lack of expansive analyses of Black male athletes from diverse backgrounds. Grounded in empirical research, this text outlines five socialization models of Black male holistic (under)development through sport and (mis)education. The five socialization models include: (a) illusion of singular success model (ISSM), (b) elite athlete lottery model (EALM), (c) transition recovery model (TRM), (d) purposeful participation for expansive personal growth model (P2EPGM), and (e) holistic empowerment model (HEM). Using ecological, race-based, gender-based, psychological, and athletic-based theories, each of the proposed models incorporates critical sociological insights whereby multi-level system factors (sub, chrono, macro, exo, meso, and micro) along with various intersecting identities and additional background characteristics are taken into account. In addition, historical, sociocultural, political, and economic conditions are examined in relation to their influence on Black males' socialization in and through sport and (mis)education. This nuanced analysis allows for the development of a systematic blueprint for Black male athletes' holistic development and more importantly collective racial and cultural uplift.

Clinical professionalism is a set of values, behaviours and relationships which underpins the public's trust in healthcare providers both as individuals and organisations. 'First, do no harm' is expressed most clearly today in the patient safety movement and the imperative for transparency and candour in the delivery of healthcare. Professional conduct is essential for safe and high quality clinical care. The ABC of Clinical Professionalism considers recent evidence on how healthcare practitioners maintain professionalism including how values are developed and affected by the working environment, the challenges of maintaining personal and organisational resilience and the ethical and regulatory framework in which practice is conducted. Topics covered include: Acquiring and developing professional values Patient-centred care Burnout and resilience Confidentiality and social media The culture of healthcare Ensuring patient safety Leadership and collaboration Ethical and legal aspects of professionalism Teaching and assessing professionalism Regulation of healthcare professionals The chapter authors come from a range of countries and have experience of working in multidisciplinary clinical teams, research, and in the training of future healthcare practitioners including their development as professionals.

Named a Top Five Book of 2011 by Physics Today, USA.'... the editors deserve praise for the selection of topics and for enlisting a distinguished set of authors. BCS: 50 Years is a successful attempt to capture the history of the development of superconductivity theory and its continuing impact. Any person curious about superconductivity will find something in this book to enjoy.'Physics TodayThe BCS theory of superconductivity developed in 1957 by Bardeen, Cooper and Schrieffer has been remarkably successful in explaining the properties of superconductors. In addition, concepts from BCS have been incorporated into diverse fields of physics, from nuclear physics and dense quark matter to the current standard model. Practical applications include SQUIDs, magnetic resonance imaging, superconducting electronics and the transmission of electricity. This invaluable book is a compilation of both a historical account and a discussion of the current state of theory and experiment.With contributions from many prominent scientists, it aims to introduce students and researchers to the origins, the impact and the current state of the BCS theory.

Named a Top Five Book of 2011 by Physics Today, USA.'... the editors deserve praise for the selection of topics and for enlisting a distinguished set of authors. BCS: 50 Years is a successful attempt to capture the history of the development of superconductivity theory and its continuing impact. Any person curious about superconductivity will find something in this book to enjoy.'Physics TodayThe BCS theory of superconductivity developed in 1957 by Bardeen, Cooper and Schrieffer has been remarkably successful in explaining the properties of superconductors. In addition, concepts from BCS have been incorporated into diverse fields of physics, from nuclear physics and dense quark matter to the current standard model. Practical applications include SQUIDs, magnetic resonance imaging, superconducting electronics and the transmission of electricity. This invaluable book is a compilation of both a historical account and a discussion of the current state of theory and experiment.With contributions from many prominent scientists, it aims to introduce students and researchers to the origins, the impact and the current state of the BCS theory.

The twentieth century witnessed an explosion of new nations carved out of existing ramshackle empires and multiethnic states. Many observers contend that the creation of new states will continue indefinitely, with the two hundred of today becoming the four hundred of tomorrow as more groups seek independence. This provocative and compelling book explores the impact of globalization and terrorism on this trend, arguing convincingly that the era of national self-determination has finally come to an end. Examining the forces that determine the emergence of new nation-states, the distinguished contributors consider a rich array of specific cases from the Middle East, Asia, North America, Europe, and Russia where new states could be created. They contend that globalization, rather than expanding such opportunities, is not as friendly to new weak states with limited resources as it is to established rich nations. Given the vast sums circulating in the world market, few fledgling nations can be financially independent. They find it more prudent to shelter within the protective embrace of existing federations. Equally, governments of federal states can induce restive petitioners_such as Quebec, Scotland, and the Basques_to remain inside the metropolitan boundary through a system of tangible restraints and rewards. Those who reject the benefits, such as rebels in Chechnya and Aceh, will fail in their bids for independence. Taiwan_poised on a knife-edge between integration with China and independence_faces a series of costs and diminished returns if it seeks full statehood. Finally, terrorism has lost its legitimacy as a technique for gaining independence in the eyes of the international community. Despite the stall in new state formation, there has been no sign of successful military or imperial expansion by established countries toward consolidation into fewer, larger national units. Neither aggression by regional states_such as the Iraq invasion of Kuwait in 1990, nor intervention_such as the U.S. occupation of Iraq in 2003, are likely to succeed. On balance, the book concludes, discontented national movements will have to find ways to exist within current geopolitical boundaries.

The twentieth century witnessed an explosion of new nations carved out of existing ramshackle empires and multiethnic states. Many observers contend that the creation of new states will continue indefinitely, with the two hundred of today becoming the four hundred of tomorrow as more groups seek independence. This provocative and compelling book explores the impact of globalization and terrorism on this trend, arguing convincingly that the era of national self-determination has finally come to an end. Examining the forces that determine the emergence of new nation-states, the distinguished contributors consider a rich array of specific cases from the Middle East, Asia, North America, Europe, and Russia where new states could be created. They contend that globalization, rather than expanding such opportunities, is not as friendly to new weak states with limited resources as it is to established rich nations. Given the vast sums circulating in the world market, few fledgling nations can be financially independent. They find it more prudent to shelter within the protective embrace of existing federations. Equally, governments of federal states can induce restive petitioners such as Quebec, Scotland, and the Basques to remain inside the metropolitan boundary through a system of tangible restraints and rewards. Those who reject the benefits, such as rebels in Chechnya and Aceh, will fail in their bids for independence. Taiwan poised on a knife-edge between integration with China and independence faces a series of costs and diminished returns if it seeks full statehood. Finally, terrorism has lost its legitimacy as a technique for gaining independence in the eyes of the international community. Despite the stall in new state formation, there has been no sign of successful military or imperial expansion by established countries toward consolidation into fewer, larger national units. Neither aggression by regional states such as the Iraq invasion of Kuwait in 1990, nor intervention such as the U.S. occupation"

Arguing that the energy price policies of the 1970s represented a major equity/efficiency trade-off and led to a dramatic deterioration in the living standard of lower income households, the authors of this book present a comprehensive data-based assessment of the plight of lower income households during the decade of 1973-1983. After a general review of the recessionary and inflationary impact of rising energy prices on the national economy, they present detailed empirical assessments of three trends adversely affecting lower income households: (1) the rising share of household energy expenditures as a percentage of household income and the failure of income transfer programs to offset losses in purchasing power; (2) the rapid increase in energy-related operating costs in lower income rental housing and the coincident decline in the quality of housing; and (3) the rapid increase in energy-related operating costs of local governments which strained local fiscal resources and led to a cutback in the provision of redistributive services (such as health, education, and welfare) and a shift toward regressive taxes. The authors conclude that damage to the national economy and to the living standards of lower income households remains severe; price trends of the 1980s, they emphasize, represent only slight moderations of earlier trends, while the vulnerability to future energy price shocks has been reduced very little. The need for effective policy responses is even greater now than in the first decade of the energy crisis.

Clinical communication underpins safe patient care. The effective health professional sees illness through the patient's eyes and understands what matters most to him or her. Effectiveness means gathering hard clinical data about the physical changes affecting the patient, understanding why the patient is concerned, conveying this to other health care professionals and involving the patient at every stage of management decisions. The evidence for good clinical communication is well established, although there are challenges. While listening is the basis of sound diagnosis and clinical reasoning, its absence affects patient outcomes particularly when patients are not permitted to make their concerns known or when there are gaps in information flow or communication between the professionals caring for them. The ABC of Clinical Communication considers the evidence pertinent to individual encounters between patients and their health professionals, how to achieve efficient flow of information, the function of clinical teams and developing a teaching programme. Topics covered include: The consultation Clinical communication and personality type Shared decision making Communication in clinical teams Communication in medical records Communication in specific situations, including mental health and end of life Teaching clinical communication The chapter authors are clinicians involved in communicating with patients, research and training healthcare professionals of the future. This team reflects the multidisciplinary approach required to develop effective clinical communication.

Previous critics have documented the damaging effects of the current exploitative sporting and education structures in the United States on Black males and the broader Black community. However, largely missing from scholarly literature and popular discourses on this topic is a comprehensive analysis of the heterogeneity among Black male athletes' lived experiences and outcomes over their lifespans. From Exploitation Back to Empowerment: Black Male Holistic (Under)Development Through Sport and (Mis)Education by Joseph N. Cooper addresses three major issues: (1) the under theorization of Black male athletes' socialization processes, (2) the preponderance of deficit-based theories on Black male athletes, and (3) the lack of expansive analyses of Black male athletes from diverse backgrounds. Grounded in empirical research, this text outlines five socialization models of Black male holistic (under)development through sport and (mis)education. The five socialization models include: (a) illusion of singular success model (ISSM), (b) elite athlete lottery model (EALM), (c) transition recovery model (TRM), (d) purposeful participation for expansive personal growth model (P2EPGM), and (e) holistic empowerment model (HEM). Using ecological, race-based, gender-based, psychological, and athletic-based theories, each of the proposed models incorporates critical sociological insights whereby multi-level system factors (sub, chrono, macro, exo, meso, and micro) along with various intersecting identities and additional background characteristics are taken into account. In addition, historical, sociocultural, political, and economic conditions are examined in relation to their influence on Black males' socialization in and through sport and (mis)education. This nuanced analysis allows for the development of a systematic blueprint for Black male athletes' holistic development and more importantly collective racial and cultural uplift.

Neurofibromatosis type 1 (NF1), caused by mutational inactivation of the NF1 tumour suppressor gene, is one of the most common dominantly inherited human disorders, affecting 1 in 3000 individuals worldwide. This book presents in concise fashion, but as comprehensively as possible, our current state of knowledge on the molecular genetics, molecular biology and cellular biology of this tumour predisposition syndrome. Written by internationally recognized experts in the field, the 44 chapters that constitute this edited volume provide the reader with a broad overview of the clinical features of the disease, the structure and expression of the NF1 gene, its germ line and somatic mutational spectra and genotype-phenotype relationships, the structure and function of its protein product (neurofibromin), NF1 modifying loci, the molecular pathology of NF1-associated tumours, animal models of the disease, psycho-social aspects and future prospects for therapeutic treatment.

Lung cancer is the leading cause of cancer mortality in Western countries. It also provides an archetypal example of how inherited predisposing genetic variants may interact with an environmental influence (smoking) to modulate individual cancer risk.

The Molecular Genetics of Lung Cancer describes how the new techniques, methods and approaches of molecular genetics are being used to unravel the complexities of the mechanisms underlying lung tumorigenesis by analysis at the DNA, RNA and protein levels with potentially important implications for tumour classification, diagnosis, prognosis and treatment as well as providing new insights into how lung tumours arise and how they progress to malignancy.

The book provides critical perspectives that reach beyond the technical approaches of international financial institutions and proponents of the liberal peace formula. It investigates political economies characterized by the legacies of disruption to production and exchange, by population displacement, poverty, and by 'criminality'.

How we see the world - our attitudes and assumptions about it - profoundly affects the way we deal with it. This book is written by an interdisciplinary team of ecologists, nature conservationists and environmental philosophers. It seeks to make the connection between the theoretical approaches to the valuation of the natural world and how these work in practice.

Being a good clinician is not just about knowledge how doctors and other healthcare professionals think, reason and make decisions is arguably their most critical skill. While medical schools and postgraduate training programmes teach and assess the knowledge and skills required to practice as a doctor, few offer comprehensive training in clinical reasoning or decision making. This is important because studies suggest that diagnostic error is common and results in significant harm to patients and errors in reasoning account for the majority of diagnostic errors. The ABC of Clinical Reasoning covers core elements of the thinking and decision making associated with clinical practice from what clinical reasoning is, what it involves and how to teach it. Informed by the latest advances in cognitive psychology, education and studies of expertise, the ABC covers: * Evidence-based history and examination * Use and interpretation of diagnostic tests * How doctors think models of clinical reasoning * Cognitive and affective biases * Metacognition and cognitive de-biasing strategies * Patient-centred evidence based medicine * Teaching clinical reasoning From an international team of authors, the ABC of Clinical Reasoning is essential reading for all students, medical professionals and other clinicians involved in diagnosis, in order to improve their decision-making skills and provide better patient care.

Does science have limits? Where does order come from? Can we understand consciousness? Written by Nobel Laureate Leon N. Cooper, this book places pressing scientific questions in the broader context of how they relate to human experience. Widely considered to be a highly original thinker, Cooper has written and given talks on a large variety of subjects, ranging from the relationship between art and science, possible limits of science, to the relevance of the Turing test. These essays and talks have been brought together for the first time in this fascinating book, giving readers an opportunity to experience Cooper's unique perspective on a range of subjects. Tackling a diverse spectrum of topics, from the conflict of faith and science to whether understanding neural networks could lead to machines that think like humans, this book will captivate anyone interested in the interaction of science with society.

The world of postgraduate medical education is changing, and educational supervisors need the knowledge and skills to be able to do their job effectively. Many of those who want to do this job well feel unprepared for the task. Essential Guide to Educational Supervision is a handbook for educational supervisors everywhere. The topics covered are generic to medical education, whatever the specialty. Although the focus is on postgraduate medical education, many of the topics in this book are also applicable to undergraduates. Essential Guide to Educational Supervision is written for: Consultants and General Practitioners who work with trainees Educational supervisors People who organise postgraduate training programmes Written by experts in their field, each chapter gives an overview of key topics in educational supervision with references and further resources. The book provides evidence and theory when applicable, but is deliberately practical, with case studies and tips for good practice as well.