Lung cancer is the leading cause of cancer mortality in Western
countries. It also provides an archetypal example of how inherited
predisposing genetic variants may interact with an environmental
influence (smoking) to modulate individual cancer risk.
The Molecular Genetics of Lung Cancer describes how the new
techniques, methods and approaches of molecular genetics are being
used to unravel the complexities of the mechanisms underlying lung
tumorigenesis by analysis at the DNA, RNA and protein levels with
potentially important implications for tumour classification,
diagnosis, prognosis and treatment as well as providing new
insights into how lung tumours arise and how they progress to
malignancy.
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