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Over the last few decades, the rapid and vast development of
advanced microbial bioresources and metagenomics techniques has
completely transformed the field of microbial biotechnology. Our
understanding of microbial diversity, evolutionary biology, and
microbial interaction with their animal and plant hosts at
molecular level has been revolutionized with an abundance of new
research. This new volume, Advances in Microbial Biotechnology:
Current Trends and Future Prospect, focuses on the application of
microorganisms for several purposes: for plant protection and
improvement, for environmental remediation purposes, and for the
improvement of human health. Various applications of microorganisms
are covered broadly and have been appropriately reflected in depth
in different chapters. The book is divided into four major
sections: applied microbiology in agriculture microbes in the
environment microbes in human health microbes in nanotechnology The
book provides insight into the diverse microorganisms that have
been explored and exploited in the development of various
applications for agricultural improvements. The book also looks at
the application of microbes for the removal of pollutants and the
recovery of metals and oils. Also discussed is the detection and
exploitation of microorganisms in the diagnosis of human diseases,
providing possible holistic approaches to health. This new volume
will provide a wealth of information on new research on the
application of microbial biotechnology today.
This book reviews applications of nanomaterial and nanodevices in
the food industry. It also discusses the advanced bioanalytical
techniques, including Enzyme-Linked Immunosorbent Assay (ELISA),
immunoanalytical techniques, and monoclonal antibody-based
immunological techniques for detecting food adulterations and
allergens. It comprehensively covers electrode modification and
nano-engineered fabrication of biosensors to enhance their
functionalities for utilization in food industries. The book
highlights the utilization of nanobiosensors for food safety and
quality analysis, such as detection of toxin, food-borne pathogen,
allergen, evaluation of toxicity etc. Further, it also summarizes
the recent advances in nanodevices such as nano-systems,
nano-emulsions, nanopesticides, and nanocapsules and their
applications in the food industry. Lastly, it covers
nanomaterial-based sensors for drug analysis in diverse matrices.
It serves as an invaluable source of information for professionals,
researchers, academicians, and students related to food science and
technology.
This book presents tools and techniques for the development of
miniature biosensors and their applications. The initial chapters
discuss the advancements in the development of the transduction
techniques, including optical, electrochemical, and piezoelectric,
which are used for miniaturized biosensors. The book also reviews
several technologies, such as nanotechnology, nanobiotechnology,
immune-technology, DNA-technology, micro-manufacturing technology,
electronic-circuit technology to increase the miniaturization and
sensitivity of the biosensor platform. Subsequently, the chapters
illustrate the applications of miniaturized biosensing systems in
point-of-care monitoring of treatment and disease progression,
environmental monitoring, food control, drug discovery, forensics,
and biomedical research. Towards the end, the book discusses the
advanced applications of biosensors in water quality monitoring,
especially on-line detection systems and on-site detection of
pesticides, heavy metals and bacteria in water. This book is an
invaluable source for scientists working in biochemical
engineering, bioengineering, and biomedical engineering in academia
and industry.
This book presents the timeline of immunodiagnostics evolution,
including advancements in immunological/nucleic acid probes, assay
design, labelling techniques, and devices for signal transduction
and acquisition. In the past few years, enzyme and
nanocatalyst-based immune assays have undergone numerous
modifications to enhance their sensitivity and potential for
automation. Further, to reduce production costs and the use of
laboratory animals, engineering small antibodies and nucleic acid
probes (aptamers) has become increasingly popular in the
development of novel and powerful bioassays. In light of the
notable advancements in immunodiagnostics, this book highlights the
combined efforts of clinicians, biotechnologists, material
scientists, nanotechnologists and basic scientists in a coherent
and highly structured way. The book takes readers on the journey of
immunodiagnostic technologies, from their introduction to the
present.
This book presents the timeline of immunodiagnostics evolution,
including advancements in immunological/nucleic acid probes, assay
design, labelling techniques, and devices for signal transduction
and acquisition. In the past few years, enzyme and
nanocatalyst-based immune assays have undergone numerous
modifications to enhance their sensitivity and potential for
automation. Further, to reduce production costs and the use of
laboratory animals, engineering small antibodies and nucleic acid
probes (aptamers) has become increasingly popular in the
development of novel and powerful bioassays. In light of the
notable advancements in immunodiagnostics, this book highlights the
combined efforts of clinicians, biotechnologists, material
scientists, nanotechnologists and basic scientists in a coherent
and highly structured way. The book takes readers on the journey of
immunodiagnostic technologies, from their introduction to the
present.
Nanobioanalytical Approaches to Medical Diagnostics reviews a range
of nanobiomaterials and bioanalytical nano-devices for medical
diagnostics. Nanobiomaterials and nano-devices are used in various
bioanalytical and biochemical systems to provide real-time,
point-of-care diagnostics. The specialized properties of
nanoparticles allow them to be engineered and adapted to produce
the required effect within a bioanalytical or biochemical system -
offering targeted and detailed diagnostic results in a range of
biomedical applications. This book covers both traditional
biochemical and modern, combined nano-approaches to medical
diagnostics. Chapters detail a range of in vitro, in vivo and ex
vivo models for nanobioanalytics, including DNA and peptide-based,
erythrocyte, microfluidic and more. In addition, sections also look
at various different medical diagnostic applications, such as in
cancer detection, infectious disease diagnosis and blood glucose
sensing.
Over the last few decades, the rapid and vast development of
advanced microbial bioresources and metagenomics techniques has
completely transformed the field of microbial biotechnology. Our
understanding of microbial diversity, evolutionary biology, and
microbial interaction with their animal and plant hosts at
molecular level has been revolutionized with an abundance of new
research. This new volume, Advances in Microbial Biotechnology:
Current Trends and Future Prospect, focuses on the application of
microorganisms for several purposes: for plant protection and
improvement, for environmental remediation purposes, and for the
improvement of human health. Various applications of microorganisms
are covered broadly and have been appropriately reflected in depth
in different chapters. The book is divided into four major
sections: applied microbiology in agriculture microbes in the
environment microbes in human health microbes in nanotechnology The
book provides insight into the diverse microorganisms that have
been explored and exploited in the development of various
applications for agricultural improvements. The book also looks at
the application of microbes for the removal of pollutants and the
recovery of metals and oils. Also discussed is the detection and
exploitation of microorganisms in the diagnosis of human diseases,
providing possible holistic approaches to health. This new volume
will provide a wealth of information on new research on the
application of microbial biotechnology today.
This book chronicles the role of advanced nanomaterials and surface
engineering technologies in the development of point-of-care
biosensors for health and environmental monitoring. All aspects of
nanomaterial synthesis and characterization, functionalization
methods, sensing surface engineering, signal amplification
strategies, use of innovative technologies to enhance sensor
efficiency and performances, and innovative applications of
nanobiosensors to tackle real-life problems are discussed in this
book with a focus on optical and electrochemical based sensing. It
also covers the detection of infectious diseases and various
disease biomarkers, smartphone-based biosensing, and portable
diagnostics module developments with a discussion on the working
mechanisms of these devices in various domains. The book also
illustrates the recent trends in biosensing, and an overview of the
challenges and probable solutions for the translation of biosensors
from laboratory prototypes to commercial success. ​
This book reviews applications of nanomaterial and nanodevices in
the food industry. It also discusses the advanced bioanalytical
techniques, including Enzyme-Linked Immunosorbent Assay (ELISA),
immunoanalytical techniques, monoclonal antibody-based
immunological techniques for detecting food adulterations and
allergens. It comprehensively covers electrode modification and
nano-engineered fabrication of biosensors to enhance their
functionalities for utilization in food industries. The book
highlights the utilization of nanobiosensors for food safety and
quality analysis, such as detection of toxin, food-borne pathogen,
allergen, and evaluation of toxicity. Further, it also summarizes
the recent advances in nanodevices such as nano-systems,
nano-emulsions, nanopesticide, nanocapsule and their applications
in the food industry. Lastly, it covers nanomaterial-based sensors
for drug analysis in diverse matrices. It serves as an invaluable
source of information for professionals, researchers, academicians,
and students related to food science and technology.
This volume focuses on the fundamentals and advancements in micro
and nanomanufacturing technologies applied in the biomedical and
biochemical domain. The contents of this volume provide
comprehensive coverage of the physical principles of advanced
manufacturing technologies and the know-how of their applications
in the fabrication of biomedical devices and systems. The book
begins by documenting the journey of miniaturization and micro-and
nano-fabrication. It then delves into the fundamentals of various
advanced technologies such as micro-wire moulding, 3D printing,
lithography, imprinting, direct laser machining, and laser-induced
plasma-assisted machining. It also covers laser-based technologies
which are a promising option due to their flexibility, ease in
control and application, high precision, and availability. These
technologies can be employed to process several materials such as
glass, polymers: polycarbonate, polydimethylsiloxane,
polymethylmethacrylate, and metals such as stainless steel, which
are commonly used in the fabrication of biomedical devices, such as
microfluidic technology, optical and fiber-optic sensors, and
electro-chemical bio-sensors. It also discusses advancements in
various MEMS/NEMS based technologies and their applications in
energy conversion and storage devices. The chapters are written by
experts from the fields of micro- and nano-manufacturing, materials
engineering, nano-biotechnology, and end-users such as clinicians,
engineers, academicians of interdisciplinary background. This book
will be a useful guide for academia and industry alike.
This volume focuses on the fundamentals and advancements in micro
and nanomanufacturing technologies applied in the biomedical and
biochemical domain. The contents of this volume provide
comprehensive coverage of the physical principles of advanced
manufacturing technologies and the know-how of their applications
in the fabrication of biomedical devices and systems. The book
begins by documenting the journey of miniaturization and micro-and
nano-fabrication. It then delves into the fundamentals of various
advanced technologies such as micro-wire moulding, 3D printing,
lithography, imprinting, direct laser machining, and laser-induced
plasma-assisted machining. It also covers laser-based technologies
which are a promising option due to their flexibility, ease in
control and application, high precision, and availability. These
technologies can be employed to process several materials such as
glass, polymers: polycarbonate, polydimethylsiloxane,
polymethylmethacrylate, and metals such as stainless steel, which
are commonly used in the fabrication of biomedical devices, such as
microfluidic technology, optical and fiber-optic sensors, and
electro-chemical bio-sensors. It also discusses advancements in
various MEMS/NEMS based technologies and their applications in
energy conversion and storage devices. The chapters are written by
experts from the fields of micro- and nano-manufacturing, materials
engineering, nano-biotechnology, and end-users such as clinicians,
engineers, academicians of interdisciplinary background. This book
will be a useful guide for academia and industry alike.
This book reviews applications of nanomaterial and nanodevices in
the food industry. It also discusses the advanced bioanalytical
techniques, including Enzyme-Linked Immunosorbent Assay (ELISA),
immunoanalytical techniques, and monoclonal antibody-based
immunological techniques for detecting food adulterations and
allergens. It comprehensively covers electrode modification and
nano-engineered fabrication of biosensors to enhance their
functionalities for utilization in food industries. The book
highlights the utilization of nanobiosensors for food safety and
quality analysis, such as detection of toxin, food-borne pathogen,
allergen, evaluation of toxicity etc. Further, it also summarizes
the recent advances in nanodevices such as nano-systems,
nano-emulsions, nanopesticides, and nanocapsules and their
applications in the food industry. Lastly, it covers
nanomaterial-based sensors for drug analysis in diverse matrices.
It serves as an invaluable source of information for professionals,
researchers, academicians, and students related to food science and
technology.
This book presents tools and techniques for the development of
miniature biosensors and their applications. The initial chapters
discuss the advancements in the development of the transduction
techniques, including optical, electrochemical, and piezoelectric,
which are used for miniaturized biosensors. The book also reviews
several technologies, such as nanotechnology, nanobiotechnology,
immune-technology, DNA-technology, micro-manufacturing technology,
electronic-circuit technology to increase the miniaturization and
sensitivity of the biosensor platform. Subsequently, the chapters
illustrate the applications of miniaturized biosensing systems in
point-of-care monitoring of treatment and disease progression,
environmental monitoring, food control, drug discovery, forensics,
and biomedical research. Towards the end, the book discusses the
advanced applications of biosensors in water quality monitoring,
especially on-line detection systems and on-site detection of
pesticides, heavy metals and bacteria in water. This book is an
invaluable source for scientists working in biochemical
engineering, bioengineering, and biomedical engineering in academia
and industry.
This book reviews applications of nanomaterial and nanodevices in
the food industry. It also discusses the advanced bioanalytical
techniques, including Enzyme-Linked Immunosorbent Assay (ELISA),
immunoanalytical techniques, monoclonal antibody-based
immunological techniques for detecting food adulterations and
allergens. It comprehensively covers electrode modification and
nano-engineered fabrication of biosensors to enhance their
functionalities for utilization in food industries. The book
highlights the utilization of nanobiosensors for food safety and
quality analysis, such as detection of toxin, food-borne pathogen,
allergen, and evaluation of toxicity. Further, it also summarizes
the recent advances in nanodevices such as nano-systems,
nano-emulsions, nanopesticide, nanocapsule and their applications
in the food industry. Lastly, it covers nanomaterial-based sensors
for drug analysis in diverse matrices. It serves as an invaluable
source of information for professionals, researchers, academicians,
and students related to food science and technology.
Nanobiosensors have been successful for in vitro as well as in vivo
detection of several biomolecules and it is expected that this
technology will revolutionize point-of-care and personalized
diagnostics, and will be extremely applicable for early disease
detection and therapeutic applications. This book describes the
emerging nanobiosensor technologies which are geared towards onsite
clinical applications and those which can be used as a personalised
diagnostic device. Biosensor technologies and materials covered
include electrochemical biosensors; implantable microbiosensors;
microfluidic technology; surface plasmon resonance-based
technologies; optical and fibre-optic sensors; lateral flow
biosensors; lab on a chip; nanomaterials based (graphene,
nanoparticles, nanocomposites, and other carbon nanomaterial)
sensors; metallic nanobiosensors; wearable and doppler-based
non-contact vital signs biosensors; and technologies for smartphone
based disease diagnosis. Clinical applications of these
technologies covered in this book include detection of various
protein biomarkers, small molecules, cancer and bacterial cells;
detection of foodborne pathogens; generation and optimisation of
antibodies for biosensor applications; microRNAs and their
applications in diagnosis for osteoarthritis; detection of
circulating tumor cells; online heartbeat monitoring; analysis of
drugs in body fluids; sensing of nucleic acids; and monitoring
oxidative stress.
This book provides up-to-date information on the prototypes used to
develop medical devices and explains the principles of biosensing
and theranostics. It also discusses the development of biosensor
and application-orientated design of medical devices. In addition
to summarizing the clinical validation of the developed techniques
and devices and the regulatory steps involved in their
commercialization, the book highlights the latest research and
translational technologies toward the development of point-of-care
devices in the health care. Lastly, it explores the current
opportunities, challenges and provides troubleshooting on the use
of biosensors in precision medicine. The book is helpful for
researchers and medical professionals working in the field of
clinical theranostics, and medical-device development wanting to
gain a better understanding into the principles and processes
involved in the development of biosensors.
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