Nanobiosensors have been successful for in vitro as well as in vivo
detection of several biomolecules and it is expected that this
technology will revolutionize point-of-care and personalized
diagnostics, and will be extremely applicable for early disease
detection and therapeutic applications. This book describes the
emerging nanobiosensor technologies which are geared towards onsite
clinical applications and those which can be used as a personalised
diagnostic device. Biosensor technologies and materials covered
include electrochemical biosensors; implantable microbiosensors;
microfluidic technology; surface plasmon resonance-based
technologies; optical and fibre-optic sensors; lateral flow
biosensors; lab on a chip; nanomaterials based (graphene,
nanoparticles, nanocomposites, and other carbon nanomaterial)
sensors; metallic nanobiosensors; wearable and doppler-based
non-contact vital signs biosensors; and technologies for smartphone
based disease diagnosis. Clinical applications of these
technologies covered in this book include detection of various
protein biomarkers, small molecules, cancer and bacterial cells;
detection of foodborne pathogens; generation and optimisation of
antibodies for biosensor applications; microRNAs and their
applications in diagnosis for osteoarthritis; detection of
circulating tumor cells; online heartbeat monitoring; analysis of
drugs in body fluids; sensing of nucleic acids; and monitoring
oxidative stress.
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