Conceptual Breakthroughs in the Evolutionary Biology of Aging continues the innovative Conceptual Breakthroughs series by providing a comprehensive outline of the major breakthroughs that built the evolutionary biology of aging as a leading scientific field. Following the evolutionary study of aging from its humble origins to the present, the book's chapters treat the field’s breakthroughs one at a time. Users will find a concise and accessible analysis of the science of aging viewed through an evolutionary lens. Building upon widely-cited studies conducted by author Michael Rose, this book covers 30 subsequent years of growth and development within the field. The book highlights key publications for those who are not experts in the field, providing an important resource for researchers. Given the prevailing interest in changing the aging process dramatically, it is a powerful tool for readers who have a vested interest in understanding its causes and future control measures.

Volume Immunodeficiency Diseases in Springer's gold-standard reference work on medical immunology focuses on infectious diseases. In tandem with its three counterpart volumes it offers the most wide-ranging and authoritative repository of knowledge on infectious diseases, with readily accessed contributions by the world's leading authorities on the subject. The encyclopedia covers the material from all angles, with more than 1000 pages of essays on the genetics, physiology, metabolism, pathogenesis and applied microbiology of all known infectious diseases, and includes access to an e-reference work that will include ongoing updates reflecting the latest advances in the field. An outstanding new resource of immense value to a wide range of medical researchers and practitioners, the encyclopedia features a user-friendly subdivision of diseases according to their affective locus in the human body. The sections cover integumentary, skeletal, respiratory, digestive, urinary, and reproductive transmissible pathogens. This high-profile encyclopedia will be an essential addition to academic libraries worldwide.

Dr. Muir and Dr. Rose are key opinion leaders in the area of endocrinology, and they have created a state-of-the-art issue for neonatologists. The clinical reviews will prepare perinatologists and neonatologists for the challenges in clinical endocrinology that arise in fetuses and newborns. More specifically, authors will provide updates on the biological basis of disorders in order to illustrate the rationale for diagnostic approaches and current therapies and to provide readers with a basis to consider and evaluate new clinical offerings. Articles on the following topics are included in the issue: Congenital hypothyroidism; Thyroid function in the NICU; Neonatal thyrotoxicosis; Neonatal diabetes; Hypersinsulinism; Hypopituitarism; Glucocorticoid use in the NICU/ neonatal adrenal function; Adrenal insufficiency, CAH, Prenatal treatment of CAH; Neonatal Cushing Disease/Congenital endocrine tumors; Early ID of Turner Syndrome/Preserving fertility; and Bone mineral/ Calcium disorders in the neonate.

Now in paperback. This book recognizes the accomplishements of American women athletes in the 100 years between 1887 and 1997. Cloth edition 0-8108-2205-9 originally published in 1985.

This book documents what happens when people encounter public officials. It draws on multi-national Barometer surveys asking questions about corruption and bribery in 119 countries. Clear prose, tables and figures report the answers given by more than 250,000 people and the conclusion sets out six principles for reducing bribery.

An examination of the long-ignored vicious side to the legend of Brazilian President Getulio Dornelles Vargas, this is the tale uncovered by the first civilian to spend months in the secret police archives of Rio de Janeiro. Rose has utilized new eyewitness testimony and insider information in offering explanations to several events that proved pivotal in Brazil during the 1930s and 1940s. During Vargas's tenure, the quality and quantity of human rights abuses reached unprecedented heights. Violence, as a means of coercing the public, was evident in all sectors of the security apparatus. Several tools of torture developed during the hunt for communists are still in use today. Almost by definition, politicians have to offer a semblance of providing something for each different sector of society. Vargas was better at this than his predecessors in that with ease he proudly wore the various vestments of dictator, fascist, democrat, and populist as necessary. For the poor, he was the paternalistic benefactor; for the middle class, he was the one who brought stability; and for the wealthy, he supported the status quo. This ability to juggle forces and interests was grounded in his security apparatus. Beginning with the unsuccessful Communist Revolution of 1935, the nation's police forces redefined and in some cases reinvented the torture that had occurred in Brazil from colonial times onward. The harshness of their methods was matched only by the ardor of their example for coming generations.

What if your entire race were created by the ancient Celtic God, Dagda, to please his beloved daughter, Brighid, who gifted your maternal bloodline with a spark of her soul? Now you're given the task of living in the mortal realm to bring the gift of the Arts to the mortals she loves; while being relentlessly hunted by the Goddess of the Killing Rage to satisfy a deadly desire for Otherworldly vengeance.

Just before Elean's seventeenth birthday, the Goddess of Lust & Rage, along with the Immortal she created, destroyed her sheltered life. Now, an object of possession by mortals and immortals alike; Elean must learn to control her legacy and, with the two warriors that love her, save the Goddess Brighid by protecting the small flame of Immortal soul that lives within her.

Liam and James have been friends...brothers...since they were children. Now the Otherworld has been released into the Mortal Realm leaving a bloody path of terror in its desire for vengeance. It's coming for Elean, a woman they both love and would die to protect. Will the Otherworld destroy their bond...or will their love for Elean give them the strength to fight what's coming?

Forced into the service of the Goddess Morrigan and made immortal, Greagoir must be the vessel for the Goddess' uncontrollable lust and killing rage. Elean is the key. After all these centuries, all that stands in his way are two mortal warriors gifted by a goddess and a young woman's desire to survive.

This Pivot book provides a framework for understanding the economic and potentially unequal effects of pandemics, focusing closely on the Spanish Flu. It provides an in-depth analysis of the different effects of the Spanish Flu on the economy from unequal mortality to wages, housing and output. There is a general review of the literature but an important feature of this book is that it explains results using data from Spain, an ideal country to perform this exercise, as its mortality data is not affected by the First World War. Spain was also developed enough to have reliable data, but it was very heterogeneous across regions which will allow a comparison of more and less developed regions. No other book exists that offers a comprehensive and data-driven view of the effects of the Spanish Flu, which is the closest pandemic example to Covid-19. With the outbreak of Covid-19 increasing the need to learn about the economic effects of pandemics, this book will be of interest to academics and students of economic history, macroeconomics (economic crises) and economic development, as well being accessible for the general reader.

Filinto Muller was the most despised police chief in Brazilian history and later a detested senator. Muller bore the brunt of many accusations of police wrongdoing owing to charges by yellow-journalist David Nasser. This volume examines the totality of Muller's life and is the result of 11 years of research in which 66,704 documents, 500 newspapers clippings, and 165 visual items were examined. Numerous interviews were likewise conducted. This work has uncovered little archival evidence to substantiate direct charges against Muller. This book argues, however, that Muller was responsible for the invention of modern-day death squads, the first of their kind in the Americas.

Volume Allergic Diseases is a comprehensive, multi-authored reference work, offering a broad appeal to microbiologists, immunologists, and infectious disease specialists. The volume explores all aspects of allergic diseases, body systems and vaccines. Emphasis is placed on genetics, physiology, metabolism, pathogenesis, and applied microbiology. Under the leadership of some of the most world renowned names in the field, the encyclopedia brings together an outstanding collection of contributions by top scientists in a variety of fields. The entries are listed alphabetically and provide full references. The volume covers the following topics: * Food Allergy and gastrointestinal Allergic Diseases * Insect Allergy * Allergy Diagnosis and Testing * Allergy Treatment: Pharmacotherapy * Asthma and Other Allergic Lower Respiratory Disease * Biology of IgE, Mast Cells and Eosinophils * Specific Allergens Causing Human Disease * Atopic Dermatitis, Urticaria and Dermatologic Allergy * Allergy Treatment: Immunotherapy, Immunomodulator Therapy and Allergen Avoidance

In regenerative medicine, tissue engineers largely rely on destructive and time-consuming techniques that do not allow in situ and spatial monitoring of tissue growth. Furthermore, once the therapy is implanted in the patient, clinicians are often unable to monitor what is happening in the body. To tackle these barriers, optical techniques have been developed to image and characterize many tissue properties, fabricate tissue engineering scaffolds, and characterize the properties of the scaffolds. Optical Techniques in Regenerative Medicine illustrates how to use optical imaging techniques and instrumentation for the fabrication, assessment, and longitudinal monitoring of regenerative medicine therapies. The book covers optical coherence tomography, acousto-optic imaging, Raman spectroscopy, machine vision, bioluminescence, second harmonic generation microscopy, multi-photon microscopy, coherent anti-Stokes Raman scattering, fluorescence spectroscopy, and light scattering spectroscopy. Each chapter provides an overview of a particular technique, its advantages and limitations in terms of structural and functional information, and examples of applications in regenerative medicine. The future evolution of regenerative medicine from academic research to viable clinical alternatives to conventional treatments is dependent on the development of non-destructive analytical techniques that can elucidate the stages of tissue development both in vitro and in vivo as well as track the fate of cells following injection. This practical book demonstrates the vital role of optical techniques in the dynamic field of regenerative medicine. It guides regenerative medicine researchers toward finding the most appropriate technique for their applications and helps biophotonics researchers see where their technologies can be applied.

This timely new book presents the concepts, context, and applications of a problem-solving approach to group work with children and adolescents. This comprehensive new volume covers it all. It addresses issues associated with assessment, problem recognition, planning and composition, leadership, and activities in a wide range of settings when working with children and adolescents. Phases of group work, practice guidelines, and evaluation are also thoroughly considered. Significant applications focus on group work with children and adolescents from families in which divorce has occurred; group work to improve peer relationships and social competence; group work with children and adolescents who are at risk for developing mental health and substance abuse disorders; and school performance group work. To help illustrate key points, a lively case example is provided for each application. A practical volume for practitioners in the helping professions, Group Work with Children and Adolescents will be highly valuable to those practicing in the fields of social work, human services, clinical and counseling psychology, and psychiatric nursing.

This work should serve as a sound foundation for students and practitioners as they begin their study of the significance of various groups in social work practice. --Choice Collective problem solving: a powerful and effective means of assessing a situation, determining a course of action, and accomplishing goals. In the realm of social services, this formidable method has been evidenced in the development of task groups; in the textbook arena, it is clearly and definitively presented in Task Groups in the Social Services. Focusing on the role of the social worker, the authors consider such aspects as the recruitment and composition of groups, participation as a team member, group shepherding, and dealing with problem behaviors within the group. Selected problem-solving approaches, including brainstorming, societal judgment analysis, and the Delphi technique, are evaluated in terms of process and outcome. From implementation through achievement, the merits and methods of application for a variety of task groups are assessed. This sophisticated work will be a vital resource for students of social work and social work practitioners alike.

This important new study is an inquiry into the origins and purposes of downwardly directed violence by economic and political elites in Brazil-violence that has led to the invention and tacit approval of contemporary death squads.

This study provides a comprehensive and balanced view of the New Age through formal studies and original research. Equal attention is accorded to practices and institutions illustrating the New Age as a concrete, living enterprise, not merely a philosophy. The book offers a thorough study of major writings by British, American and other commentators, detailed ethnographic testimony, and a broad survey of the New Age phenomenon in all its aspects.

Does Aging Stop? reveals the most paradoxical finding of recent aging research: the cessation of demographic aging. The authors show that aging stops at the level of the individual organism, and explain why evolution allows this. The implications of this counter-intuitive conclusion are profound, and aging research now needs to accept three uncomfortable truths. First, aging is not a cumulative physiological process. Second, the fundamental theory that is required to explain, manipulate, and probe the phenomena of aging comes from evolutionary biology. Third, strong-inference experimental strategies for aging must be founded in evolutionary research, not cell or molecular biology.
The result of fifteen years of research bringing together new applications of evolutionary theory, new models for demography, and massive experimentation, Does Aging Stop? advances an entirely new foundation for the scientific study of aging.

Experts in microbiology and autoimmunity examine the association between microorganisms and the development of specific categories of autoimmune diseases. The opening chapters explore the bacterial induction of diseases considered autoimmune in nature. Subsequent chapters describe the role of viruses in the induction of these diseases and of diseases with an autoimmune component. Specific topics include: the role of streptococcal infection in rheumatic fever and the role of Klebsiella in the development of ankylosing spondylitis.

Aging is one of those subjects that many biologists feel is largely unknown. Therefore, they often feel comfortable offering extremely facile generalizations that are either unsupported or directly refuted in the experimental literature. Despite this unfortunate precedent, aging is a very broad phenomenon that calls out for integration beyond the mere collecting together of results from disparate laboratory organisms. With this in mind, Part One offers several different synthetic perspectives. The editors, Rose and Finch, provide a verbal synthesis of the field that deliberately attempts to look at aging from both sides, the evolutionary and the molecular. The articles by Charlesworth and Clark both provide population genetic perspectives on aging, the former more mathematical, the latter more experimental. Bell takes a completely different approach, arguing that aging may not be the result of evolutionary forces. Bell's model instead proposes that aging could arise from the progressive deterioration of chronic host pathogen interactions. This is the first detailed publication of this model. It marks something of a return to the type of aging theories that predominated in the 1950's and 1960's, theories like the somatic mutation and error catastrophe theories. We hope that the reader will be interested by the contrast in views between the articles based on evolutionary theory and that of Bell. MR. Rose and C. E. Finch (eds. ), Genetics and Evolution of Aging, 5-12, 1994. (c) 1994 Kluwer Academic Publishers. The J aniform genetics of aging 2 Michael R. Rosel & Caleb E."

In the days when Winston Churchill and Clement Attlee faced each other in the House of Commons, there was disagreement about whose hands should be on the Mace, the symbol of power at Westminster. Everyone assumed that the hands on the Mace would be British. In the past half century, the Prime Minister's power at Westminster has increased greatly, but it has diminished in the worlds beyond.

In Westminster, the Prime Minister is now first without equal. But in councils of the European Union, he or she is only one among fifteen national leaders. In a shrinking world the chief issues facing Downing Street today are 'intermestic', an amalgam of domestic politics and international concerns. Tony Blair may say that he is batting for Britain, but cricket skills are no match for an American president playing hard ball, and policy-making in the European Union is definitely not cricket.

In an era of television politics, the faces and voices of Margaret Thatcher and Tony Blair are familiar to every voter, and the press cooperates in turning politicians into media celebrities. But what you see on the box is politics; it has little to do with the policies of British government. Old-school leaders such as Harold Macmillan devoted as much time to policy as to politics. But new-style prime ministers put politics first.

Tony Blair wants to speak for all the British people, but the result is 'managed populism', for his voice travels down a one-way street. In Whitehall, Blair's Third Way blunts the cutting edge of policy, leaving officials puzzled about what to do when hard choices arise, especially about Europe.

Anyone interested in politics and current affairs, whether a studentor a thoughtful reader and viewer, will find insight and illumination in a book that draws on the author's unrivalled first-hand knowledge of British politics over the past half century.

Richard Rose's work has been recognized by a lifetime achievement award from the Political Studies Association. He is a Fellow of the British Academy and director of the Centre for the Study of Public Policy at the University of Strathclyde.

In the days when Winston Churchill and Clement Attlee faced each other in the House of Commons, there was disagreement about whose hands should be on the Mace, the symbol of power at Westminster. Everyone assumed that the hands on the Mace would be British. In the past half century, the Prime Minister's power at Westminster has increased greatly, but it has diminished in the worlds beyond.

In Westminster, the Prime Minister is now first without equal. But in councils of the European Union, he or she is only one among fifteen national leaders. In a shrinking world the chief issues facing Downing Street today are 'intermestic', an amalgam of domestic politics and international concerns. Tony Blair may say that he is batting for Britain, but cricket skills are no match for an American president playing hard ball, and policy-making in the European Union is definitely not cricket.

In an era of television politics, the faces and voices of Margaret Thatcher and Tony Blair are familiar to every voter, and the press cooperates in turning politicians into media celebrities. But what you see on the box is politics; it has little to do with the policies of British government. Old-school leaders such as Harold Macmillan devoted as much time to policy as to politics. But new-style prime ministers put politics first.

Tony Blair wants to speak for all the British people, but the result is 'managed populism', for his voice travels down a one-way street. In Whitehall, Blair's Third Way blunts the cutting edge of policy, leaving officials puzzled about what to do when hard choices arise, especially about Europe.

Anyone interested in politics and current affairs, whether a studentor a thoughtful reader and viewer, will find insight and illumination in a book that draws on the author's unrivalled first-hand knowledge of British politics over the past half century.

Richard Rose's work has been recognized by a lifetime achievement award from the Political Studies Association. He is a Fellow of the British Academy and director of the Centre for the Study of Public Policy at the University of Strathclyde.

This unique book looks at the biology of aging from a fundamentally new perspective, one based on evolutionary theory rather than traditional concepts which emphasize molecular and cellular processes. The basis for this approach lies in the fact that natural selection, as a powerful determining force, tends to decline in importance with age. Many of the characteristics we associate with aging, the author argues, are more the result of this decline than any mechanical imperative contained within organic structures. This theory in turn yields the most fruitful avenues for seeking answers to the problem of aging, and should be recognized as the intellectual core of gerontology and the foundation for future research. The author ably surveys the vast literature on aging, presenting mathematical, experimental, and comparative findings to illustrate and support the central thesis. The result is the first complete synthesis of this vital field. Evolutionary biologists, gerontologists, and all those concerned with the science of aging will find it a stimulating, strongly argued account.

The new second edition of this forward-thinking text goes beyond the discussion of health disparities to highlight the importance of health equity. As the new title suggests, Health Equity, Diversity and Inclusion: Context, Controversies, and Solutions helps the reader understand key social justice issues relevant to health disparities and/or health equity, taking the reader from the classroom to the real world to implement new solutions. The new Second Edition features: - Two new chapters: one on the impact of urban education on urban health (Ch 4) and another covering the elderly and health equity (Ch 10) - Updated and enhanced coverage on men’s health, demographic data, the importance of cultural proficiency, maternal mortality and Black women, and much more. - Current trends and movements, including the role of social media in the provision of health care information for improved health literacy; mass incarceration and criminal justice reform; and new efforts toward resolving health disparities. - Case studies and problems that engage students in thinking about health disparities/equity and diversity issues and prompt them to consider possible solutions.