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Genetics and Evolution of Aging (Paperback, Softcover reprint of hardcover 1st ed. 1994)
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Genetics and Evolution of Aging (Paperback, Softcover reprint of hardcover 1st ed. 1994)
Series: Contemporary Issues in Genetics and Evolution, 3
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Aging is one of those subjects that many biologists feel is largely
unknown. Therefore, they often feel comfortable offering extremely
facile generalizations that are either unsupported or directly
refuted in the experimental literature. Despite this unfortunate
precedent, aging is a very broad phenomenon that calls out for
integration beyond the mere collecting together of results from
disparate laboratory organisms. With this in mind, Part One offers
several different synthetic perspectives. The editors, Rose and
Finch, provide a verbal synthesis of the field that deliberately
attempts to look at aging from both sides, the evolutionary and the
molecular. The articles by Charlesworth and Clark both provide
population genetic perspectives on aging, the former more
mathematical, the latter more experimental. Bell takes a completely
different approach, arguing that aging may not be the result of
evolutionary forces. Bell's model instead proposes that aging could
arise from the progressive deterioration of chronic host pathogen
interactions. This is the first detailed publication of this model.
It marks something of a return to the type of aging theories that
predominated in the 1950's and 1960's, theories like the somatic
mutation and error catastrophe theories. We hope that the reader
will be interested by the contrast in views between the articles
based on evolutionary theory and that of Bell. MR. Rose and C. E.
Finch (eds. ), Genetics and Evolution of Aging, 5-12, 1994. (c)
1994 Kluwer Academic Publishers. The J aniform genetics of aging 2
Michael R. Rosel & Caleb E."
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