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Published since 1959, International Review of Neurobiology is a
well-known series appealing to neuroscientists, clinicians,
psychologists, physiologists, and pharmacologists. Led by an
internationally renowned editorial board, this important serial
publishes both eclectic volumes made up of timely reviews and
thematic volumes that focus on recent progress in a specific area
of neurobiology research. This volume reviews existing theories and
current research surrounding the movement disorder
Dyskinesia. Leading authors review state-of-the-art in their field of investigation and provide their views and perspectives for future research Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist
The purpose of this work is to familiarize neuroscientists with the
available tools for proteome research and their relative abilities
and limitations. To know the identities of the thousands of
different proteins in a cell, and the modifications to these
proteins, along with how the amounts of both of these change in
different conditions would revolutionize biology and medicine.
While important strides are being made towards achieving the goal
of global mRNA analysis, mRNA is not the functional endpoint of
gene expression and mRNA expression may not directly equate with
protein expression. There are many potential applications for
proteomics in neuroscience: determination of the neuro-proteome,
comparative protein expression profiling, post-translational
protein modification profiling and mapping protein-protein
interactions, to name but a few. Functional Genomics and Proteomics
in Clinical Neuroscience will comment on all of these applications,
but with an emphasis on protein expression profiling. This book
combines the basic methodology of genomics and proteomics with the
current applications of such technologies in understanding
psychiatric illnesses.
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