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Functional Genomics and Proteomics in the Clinical Neurosciences, Volume 158 (Hardcover, 158th edition)
Loot Price: R6,447
Discovery Miles 64 470
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Functional Genomics and Proteomics in the Clinical Neurosciences, Volume 158 (Hardcover, 158th edition)
Series: Progress in Brain Research
Expected to ship within 12 - 17 working days
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The purpose of this work is to familiarize neuroscientists with the
available tools for proteome research and their relative abilities
and limitations. To know the identities of the thousands of
different proteins in a cell, and the modifications to these
proteins, along with how the amounts of both of these change in
different conditions would revolutionize biology and medicine.
While important strides are being made towards achieving the goal
of global mRNA analysis, mRNA is not the functional endpoint of
gene expression and mRNA expression may not directly equate with
protein expression. There are many potential applications for
proteomics in neuroscience: determination of the neuro-proteome,
comparative protein expression profiling, post-translational
protein modification profiling and mapping protein-protein
interactions, to name but a few. Functional Genomics and Proteomics
in Clinical Neuroscience will comment on all of these applications,
but with an emphasis on protein expression profiling. This book
combines the basic methodology of genomics and proteomics with the
current applications of such technologies in understanding
psychiatric illnesses.
* Introduction of basic methodologies in genomics and proteomics
and their integration in psychiatry
* Development of the text in sections related to methods,
application and future directions of these rapidly advancing
technologies
* Use of actual data to illustrate many principles of functional
genomics and proteomics.
* Introduction to bioinformatics and database management techniques
General
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