General compendium of HDAC inhibitors with deep emphasis on toxicity issues of synthetic HDAC inhibitors Various groups of natural HDAC inhibitors, their representatives and premier sources Cyclic tetrapeptides of natural origin and their importance as cancer chemotherapeutic agents Hydroxamates and depsipeptides from natural sources and their promising role in cancer therapy Natural Flavonoids, their HDAC inhibitory tendency and marvellous anticancer activity Non-flavonoid natural HDAC inhibitors and their pleasing cytotoxic effects towards cancer models Combined therapy involving natural flavonoids with other anticancer molecules for synergistic and additive benefits against cancer models Non-flavonoid HDAC inhibitors and conventional drugs in collaborative mode against aggressive malignancies Nanotechnology based delivery of natural HDAC inhibitors for greater therapeutic efficacy over traditional combinatorial therapy

Focusing on new technological interventions involved in the postharvest management of fruits, this volume looks at the research on maintaining the quality of fruits from farm to table. The volume examines the factors that contribute to shortening shelf life as well as innovative solutions to maintaining quality while increasing the length of time fruit remains fresh, nutritious, and edible. The volume considers the different needs of the diversity of fruits and covers a variety of important topics, including: * factors affecting the postharvest quality of fruits * microbial spoilage * decontamination of fruits by non-thermal technologies * new kinds of packaging and edible coatings * ozone as shelf-life extender of fruits. Emerging Technologies for Shelf-Life Enhancement of Fruits considers the fundamental issues and will be an important reference on shelf-life extension of fruits. Highlighting the trends in future research and development, it will provide food technologists, food engineers, and food industry professionals with new insight for prolonging the shelf life of fruits.

Whole grains play an important role in healthy diets, due to their potential role in minimizing the risk factors for several diseases. Thus the need for a comprehensive work that addresses all aspects of whole grain technology including processing, product development and nutrition values. This book covers the technological, nutritional and product development aspects of all whole grains including wheat, rice, barley, rye, sorghum, millet, maize, and oats among others. The book will review and summarize current knowledge in whole grains with the intent of being helpful to the food industry in the development of high-quality whole grain products. Key Features: Covers the technology for whole grain processing Promotes the utilization of whole grain products Provides the information about the nutritional components of whole grains Explores the health benefits of whole grains Presents the latest trends and safety concerns of whole grains The chapters include amaranth, barley, brown rice, buckwheat, maize, millets, oats, quinoa, rye, sorghum, and wheat. In addition, current trends in processing technology and product development for whole grains are explained in detail in a separate chapter. The last chapter deals with the food safety management of whole grains. Contributions from global experts in this field make this book a key reference material for all aspects of whole grains. This book is suitable for students, scientists, and professionals in food science, food engineering, food technology, food processing, product development, food marketing, nutrition and other health sciences.

There are several popular books published in Healthcare Computational Informatics like Computational Bioengineering and Bioinformatics (2020), Springer; Health Informatics (2017), Springer; Health Informatics Vision: From Data via Information to Knowledge (2019), IOS Press; Data Analytics in Biomedical Engineering and Healthcare (2020), Elsevier. However, in all these mentioned books, the challenges in Biomedical Imaging are solved in one dimension by use of any specific technology like Image Processing, Machine Learning or Computer Aided Systems.  In this book, the book it has been attempted to bring all technologies related to computational analytics together and apply them on Biomedical Imaging.

Discusses the valorization of fruit processing by-products Covers the role of the byproducts as prebiotics and dietary fibers Presents extraction techniques of bioactive compounds from fruit wastes

Overviews the issues associated with the shelf life enhancement and shelf life evaluation of various food products Addresses issues important to maintaining food safety Explains how shelf life depends on factors including ingredients for formulation, processing techniques, packaging, and storage conditions. Covers shelf life evaluation methods, determinants for shelf life, food quality assessment, and basic and innovative technologies which will improve the shelf life of food products

This book is a collection of outstanding content written by experts working in the field of multimedia security. It provides an insight about various techniques used in multimedia security and identifies its progress in both technological and algorithmic perspectives. In the contemporary world, digitization offers an effective mechanism to process, preserve and transfer all types of information. The incredible progresses in computing and communication technologies augmented by economic feasibility have revolutionized the world. The availability of efficient algorithms together with inexpensive digital recording and storage peripherals have created a multimedia era bringing conveniences to people in sharing the digital data that includes images, audio and video. The ever-increasing pace, at which the multimedia and communication technology is growing, has also made it possible to combine, replicate and distribute the content faster and easier, thereby empowering mankind by having a wealth of information at their disposal. However, security of multimedia is giving tough time to the research community around the globe, due to ever-increasing and efficient attacks carried out on multimedia data by intruders, eves-droppers and hackers. Further, duplication, unauthorized use and mal-distribution of digital content have become a serious challenge as it leads to copyright violation and is considered to be the principal reason that refrains the information providers in freely sharing their proprietary digital content. The book is useful for students, researchers and professionals to advance their study.

Market trend and the increasing diagnoses of celiac disease have encouraged extensive research into the development of gluten-free breads. Generally, the development of bread without gluten involves the use of diverse ingredients and additives aimed at imitating the viscoelastic properties of gluten and consequently obtaining quality bread products. However, developing gluten-free bread remains a technological challenge due to the key role of gluten in the breadmaking process. Gluten-Free Bread Technology provides an overview of all fundamental issues and key factors associated with gluten-free bread technology, with the emphasis on the most recent findings on the subject. The promising results of the reviewed studies indicate that the gluten-free breads developed possess similar or better sensory attributes than those of control formulations, and some are even comparable to their wheat gluten-based counterparts. Chapters of this book focus on the role of additives, dough handling, and the physical, structural, sensory and nutritional properties of the gluten-free bread. The science of gluten intolerance is explained as well. With all relevant literature gathered and summarized in one place, this text will be an essential resource for both food scientists and industry professionals pursuing gluten-free formulations.

This book reviews the latest developments in the design, synthesis, and molecular mechanism of action of Histone Deacetylase (HDAC) inhibitors in the context of potential cancer therapy. HDAC inhibitors are emerging as promising anticancer drug molecules that promote growth arrest, differentiation and apoptosis of cancer cells with tumor selective toxicity. The book begins with an overview of various epigenetic modifying enzymes that are involved in cancer transition and progression; before exploring the potential of HDACs in cancer treatment. It provides a classification of HDAC inhibitors based on their structural attributes, and addresses HDAC-induced cytotoxicity.. Lastly, it discusses and assesses the rationale behind therapies that combine HDAC inhibitors with other anticancer agents to treat solid tumors. Given its scope, it offers a valuable resource for all researchers, clinicians, and students working in formulation, drug discovery, oncology, and personalized medicine.

This edited volume provides insight into temperate fruits, with an emphasis on postharvest physiology, storage, packaging and technologies for maintaining fruit quality. Chapters are devoted to individual fruits and focus on fundamental issues such as methods for maintaining or enhancing quality, minimizing postharvest losses, and recommended technologies to boost demand. Contributions come from experts in the field, making this a key reference for all aspects of postharvest management of temperate fruits. The volume is unique in its focus on the biodiversity, nutritional and health benefits, and postharvest technologies for shelf life enhancement of temperate fruits. Contributing authors address the postharvest biology and technology of individual temperate fruits such as plum, cherry, peach, apricot, apple, pear, quince, loquat, kiwi, persimmon and berries. There has been tremendous growth in the research and development of new techniques to maintain the quality of temperate fruits from farm to table. Contributions from experts in the field cover these recent advances, providing up-to-date and relevant information for researchers, postharvest/fruit technologists, food scientists, postgraduate students, and others working in the industry.

This edited volume provides insight into temperate fruits, with an emphasis on postharvest physiology, storage, packaging and technologies for maintaining fruit quality. Chapters are devoted to individual fruits and focus on fundamental issues such as methods for maintaining or enhancing quality, minimizing postharvest losses, and recommended technologies to boost demand. Contributions come from experts in the field, making this a key reference for all aspects of postharvest management of temperate fruits. The volume is unique in its focus on the biodiversity, nutritional and health benefits, and postharvest technologies for shelf life enhancement of temperate fruits. Contributing authors address the postharvest biology and technology of individual temperate fruits such as plum, cherry, peach, apricot, apple, pear, quince, loquat, kiwi, persimmon and berries. There has been tremendous growth in the research and development of new techniques to maintain the quality of temperate fruits from farm to table. Contributions from experts in the field cover these recent advances, providing up-to-date and relevant information for researchers, postharvest/fruit technologists, food scientists, postgraduate students, and others working in the industry.

This book is a collection of outstanding content written by experts working in the field of multimedia security. It provides an insight about various techniques used in multimedia security and identifies its progress in both technological and algorithmic perspectives. In the contemporary world, digitization offers an effective mechanism to process, preserve and transfer all types of information. The incredible progresses in computing and communication technologies augmented by economic feasibility have revolutionized the world. The availability of efficient algorithms together with inexpensive digital recording and storage peripherals have created a multimedia era bringing conveniences to people in sharing the digital data that includes images, audio and video. The ever-increasing pace, at which the multimedia and communication technology is growing, has also made it possible to combine, replicate and distribute the content faster and easier, thereby empowering mankind by having a wealth of information at their disposal. However, security of multimedia is giving tough time to the research community around the globe, due to ever-increasing and efficient attacks carried out on multimedia data by intruders, eves-droppers and hackers. Further, duplication, unauthorized use and mal-distribution of digital content have become a serious challenge as it leads to copyright violation and is considered to be the principal reason that refrains the information providers in freely sharing their proprietary digital content. The book is useful for students, researchers and professionals to advance their study.

There are several popular books published in Healthcare Computational Informatics like Computational Bioengineering and Bioinformatics (2020), Springer; Health Informatics (2017), Springer; Health Informatics Vision: From Data via Information to Knowledge (2019), IOS Press; Data Analytics in Biomedical Engineering and Healthcare (2020), Elsevier. However, in all these mentioned books, the challenges in Biomedical Imaging are solved in one dimension by use of any specific technology like Image Processing, Machine Learning or Computer Aided Systems. In this book, the book it has been attempted to bring all technologies related to computational analytics together and apply them on Biomedical Imaging.

Cereal grains and their products are staples in the diet of almost every culture of the world and have made an important contribution to daily nutrient requirements. Cereal grains are high in carbohydrates, good sources of protein and provide varying amounts of fibre, vitamins and minerals. The nutritional composition of grains may vary depending on the variety and environmental growing conditions. A number of cereal products are prepared from all the regions of the world. Cereals are processed into many products such as bread, cookies, cakes and pasta and are consumed daily by the majority of the population and play an important place in human nutrition. Cereal Based Food Products is the first book of its kind, focusing on the preparation methodology of cereal products. The chapters focus on different types of cereal products, processing technology, quality aspects and packaging requirements. All of the important cereal-based foods are covered in full, including sections on bread, cookies, cakes and muffins, pasta and noodles and many more including their packaging, preparation methods and ingredients. With this text researchers will find a comprehensive single source for information on the processing of cereal-based food products. Covers different types of products prepared from cereal grains; Focuses on production technology for the development of cereal products; Presents information on packaging requirements of cereal products.

A smart ecosystem is envisioned to exchange and analyze data across systems, enabling a flexible, faster, and reliable smart ecosystem for high-quality results at reduced costs and little human intervention. This book introduces many innovative approaches and provides solutions to various problems of smart ecosystems designed by employing various techniques/models based on AI, ML, Deep Learning, and the Internet of Things (IoT). The main focus is on intelligent multimedia processing and automated decision-making for various services, real-time data analysis, data security, cost-effective solutions for multimedia applications, smart information processing systems, and smart city planning to name a few. In addition, this book presents some key insights and future directions in the various areas of technology. Throughout the book, many state-of-the-art solutions concerning various applications are proposed to solve the issues and ensure the quality of services (QoS). The authors discuss the limitations of the current techniques used to design a smart ecosystem and highlight some prospective areas of research in the future. The book comprehensively discusses multimedia processing of various forms of data comprising text, images, and audio for the implementation of various solutions. The book is aimed to open many areas of research and thus would present a comprehensive reference for the design of smart ecosystems in various applications.

Focusing on new technological interventions involved in the postharvest management of fruits, this volume looks at the research on maintaining the quality of fruits from farm to table. The volume examines the factors that contribute to shortening shelf life as well as innovative solutions to maintaining quality while increasing the length of time fruit remains fresh, nutritious, and edible. The volume considers the different needs of the diversity of fruits and covers a variety of important topics, including: * factors affecting the postharvest quality of fruits * microbial spoilage * decontamination of fruits by non-thermal technologies * new kinds of packaging and edible coatings * ozone as shelf-life extender of fruits. Emerging Technologies for Shelf-Life Enhancement of Fruits considers the fundamental issues and will be an important reference on shelf-life extension of fruits. Highlighting the trends in future research and development, it will provide food technologists, food engineers, and food industry professionals with new insight for prolonging the shelf life of fruits.

Plant Extracts in Food Applications is the first book of its kind focusing on the application of plant extracts in the food industry. Topics cover sources, extraction and encapsulation techniques, the chemistry and stability of plant extracts, antimicrobials, preservatives, nutrient enhancers, enzymes, flavoring and coloring agents, packaging aid, health benefits, opportunities and the challenges surrounding the use of plant extracts in food applications. Written by several experts in the field, this book is a valuable resource for students, scientists, and professionals in food science, food chemistry and nutrition. Concerns and potential risks regarding the use of synthetic chemicals have renewed the interests of consumers using natural and safe alternatives. Plant extracts represent an interesting ingredient, mainly due to their natural origin and phytochemical properties, allowing for obtaining active materials to extend shelf-life and add value to the product.

Market trend and the increasing diagnoses of celiac disease have encouraged extensive research into the development of gluten-free breads. Generally, the development of bread without gluten involves the use of diverse ingredients and additives aimed at imitating the viscoelastic properties of gluten and consequently obtaining quality bread products. However, developing gluten-free bread remains a technological challenge due to the key role of gluten in the breadmaking process. Gluten-Free Bread Technology provides an overview of all fundamental issues and key factors associated with gluten-free bread technology, with the emphasis on the most recent findings on the subject. The promising results of the reviewed studies indicate that the gluten-free breads developed possess similar or better sensory attributes than those of control formulations, and some are even comparable to their wheat gluten-based counterparts. Chapters of this book focus on the role of additives, dough handling, and the physical, structural, sensory and nutritional properties of the gluten-free bread. The science of gluten intolerance is explained as well. With all relevant literature gathered and summarized in one place, this text will be an essential resource for both food scientists and industry professionals pursuing gluten-free formulations.

This book reviews the latest developments in the design, synthesis, and molecular mechanism of action of Histone Deacetylase (HDAC) inhibitors in the context of potential cancer therapy. HDAC inhibitors are emerging as promising anticancer drug molecules that promote growth arrest, differentiation and apoptosis of cancer cells with tumor selective toxicity. The book begins with an overview of various epigenetic modifying enzymes that are involved in cancer transition and progression; before exploring the potential of HDACs in cancer treatment. It provides a classification of HDAC inhibitors based on their structural attributes, and addresses HDAC-induced cytotoxicity.. Lastly, it discusses and assesses the rationale behind therapies that combine HDAC inhibitors with other anticancer agents to treat solid tumors. Given its scope, it offers a valuable resource for all researchers, clinicians, and students working in formulation, drug discovery, oncology, and personalized medicine.

Results of regular monitoring of the species diversity and structure of plant communities is used by conservation biologists to help understand impacts of perturbations caused by humans and other environmental factors on ecosystems worldwide. Changes in plant communities can, for example, be a reflection of increased levels of pollution, a response to long-term climate change, or the result of shifts in land-use practices by the human population. This book presents a series of essays on the application of plant biodiversity monitoring and assessment to help prevent species extinction, ecosystem collapse, and solve problems in biodiversity conservation. It has been written by a large international team of researchers and uses case studies and examples from all over the world, and from a broad range of terrestrial and aquatic ecosystems. The book is aimed at any graduate students and researchers with a strong interest in plant biodiversity monitoring and assessment, plant community ecology, biodiversity conservation, and the environmental impacts of human activities on ecosystems.

This book focuses on the production technology of temperate nuts. It explores cultivar and plant improvement, development and selection of rootstocks, plant–water relations and irrigation, canopy architecture, and postharvest packaging of nut fruits. It also deals with organic approaches, biotechnological interventions, diseases, and pest management. Contributing authors address nut fruits such as walnut, pecan nut, chestnut, and hazel nut on different recent aspects. The development achieved in the fruit sector is indicative of the fact that there is growing demand of fruit produce. Temperate nuts with health benefits and market acceptability have best sources of fat, fiber, protein, and mineral. They provide dietary fiber, potassium, and a variety of health-protective bioactive compounds. Apart from the health benefits, production of temperate nuts improves the economy of the country as these are very good source of income and employment. In addition, there is wide diversification in the production pattern of nuts globally. Increased production technology such as hybrids, high-yielding selections/ varieties, improved propagation techniques, and increased use of fertilizers and manures have brought spectacular increase in the production of nut fruits. This book is of interest to teachers, scientists, researchers, and scholars. Also, the book serves as additional reading material for undergraduate and postgraduate students of agriculture and horticulture. Horticulture nurseries and orchard industries also find this to be a useful read.