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Time-correlated single photon counting (TCSPC) is a remarkable
technique for recording low-level light signals with extremely high
precision and picosecond-time resolution. TCSPC has developed from
an intrinsically time-consuming and one-dimensional technique into
a fast, multi-dimensional technique to record light signals. So
this reference and text describes how advanced TCSPC techniques
work and demonstrates their application to time-resolved laser
scanning microscopy, single molecule spectroscopy, photon
correlation experiments, and diffuse optical tomography of
biological tissue. It gives practical hints about constructing
suitable optical systems, choosing and using detectors, detector
safety, preamplifiers, and using the control features and
optimising the operating conditions of TCSPC devices. Advanced
TCSPC Techniques is an indispensable tool for everyone in research
and development who is confronted with the task of recording
low-intensity light signals in the picosecond and nanosecond
range.
"The monograph by Dr Wolfgang Becker is a complete and lucid
summary of both the basic principles and the state-of-the-art of
TCSPC. This book contains descriptions that are only available from
the primary literature or specialized web sites. An understanding
of the present technology will allow the reader to make effective
use of the multi-dimensional capabilities of modern time-resolved
fluorescence instruments."
Joseph R. Lakowicz, Center for Fluorescence Spectroscopy,
University of Maryland School of Medicine, Baltimore,
The Sentinel Lymph Node Concept is evaluated from the points of
view of pathology, radiodiagnosis and nuclear medicine diagnostics,
surgical treatment and clinical oncology. The concept and its
practical applications are analyzed for breast cancer, malignant
melanoma, tumors of the face, oropharynx, lung, gastrointestinal
and urogenital tracts. The first part of the book describes the
function and use of the nuclear medicine equipment, the tracers
used, colloid solutions and modern developments in histological and
immunohistochemical lymph node investigations, as well as possible
pitfalls. The consequences of false-negative results are clearly
delineated. In the second part, specific tumor-related problems are
described.
This volume contains the proceedings of the Ninth European
Conference on Eye Movements (ECEM 9), held in Ulm, Germany, on
September 23-26, 1997. ECEM 9 con tinued a series of conferences
initiated by Rudolf Groner of Bern, Switzerland, in 1981 which,
from its very beginning, has brought together scientists from very
diverse fields with a common interest in eye movements. About 40 of
the papers presented at ECEM 9 have been selected for presentation
in full length while others are rendered in condensed form. There
is a broad spectrum of motives why people have become involved in,
and fas cinated by, eye movement research. Neuroscientists have
been allured by the prospect of understanding anatomical findings,
single unit recordings, and the sequels of experimental lesions in
terms of the clearly defined system requirements and the well
documented be havioural repertoire of the oculomotor system. Others
have been attracted by the richness of this repertoire and its
dependence on an intricate hierarchy of factors spanning from
"simple" reflexes to visual pattern recognition and spatio-temporal
prediction. Neurolo gists, neuro-ophthalmologists and
neuro-otologists have long standing experience with eye movements
as sensitive indicators of lesions in the brain stem, the midbrain,
and the cere bellum. By studying oculomotor malfunctions they have
made, and are continuing to make, important contributions to our
understanding of oculomotor functions."
This book is an attempt to bridge the gap between the instrumental
principles of multi-dimensional time-correlated single photon
counting (TCSPC) and typical applications of the technique. Written
by an originator of the technique and by sucessful users, it covers
the basic principles of the technique, its interaction with optical
imaging methods and its application to a wide range of experimental
tasks in life sciences and clinical research. The book is
recommended for all users of time-resolved detection techniques in
biology, bio-chemistry, spectroscopy of live systems, live cell
microscopy, clinical imaging, spectroscopy of single molecules, and
other applications that require the detection of low-level light
signals at single-photon sensitivity and picosecond time
resolution.
This volume contains the proceedings of the Ninth European
Conference on Eye Movements (ECEM 9), held in Ulm, Germany, on
September 23-26, 1997. ECEM 9 con tinued a series of conferences
initiated by Rudolf Groner of Bern, Switzerland, in 1981 which,
from its very beginning, has brought together scientists from very
diverse fields with a common interest in eye movements. About 40 of
the papers presented at ECEM 9 have been selected for presentation
in full length while others are rendered in condensed form. There
is a broad spectrum of motives why people have become involved in,
and fas cinated by, eye movement research. Neuroscientists have
been allured by the prospect of understanding anatomical findings,
single unit recordings, and the sequels of experimental lesions in
terms of the clearly defined system requirements and the well
documented be havioural repertoire of the oculomotor system. Others
have been attracted by the richness of this repertoire and its
dependence on an intricate hierarchy of factors spanning from
"simple" reflexes to visual pattern recognition and spatio-temporal
prediction. Neurolo gists, neuro-ophthalmologists and
neuro-otologists have long standing experience with eye movements
as sensitive indicators of lesions in the brain stem, the midbrain,
and the cere bellum. By studying oculomotor malfunctions they have
made, and are continuing to make, important contributions to our
understanding of oculomotor functions."
May 2009 sees the 60th anniversary of the adoption of the Basic Law
(Constitution) of the Federal Republic of Germany. To mark this
occasion, the Foundation is publishing two keynote speeches which
Theodor Heuss delivered before the Parliamentary Council. His
opening speech on 9th September 1948 and his final speech on 8th
May 1949 are key markers for his active commitment to the work of
this constituent assembly. An essay by Prof. Jutta Limbach, former
President of the Federal Constitutional Court, completes the
volume.
Theodor Heuss is one of the most significant founders of German
politics' new political beginning in Germany. As a liberal party
politician and leader of the WA1/4rttemberg-Baden "Kultministerium"
(ministry of culture) he gained respect in all four occupied zones.
He faced his most important task during 1948/49 in the
Parlamentarischer Rat (parliamentary council), where he made an
essential contribution to the creation of the constitution. Both as
a journalist and an "educator for democracy," Heuss advocated a
moral reformation and the ruthless examination of crimes committed
by the German people under the National Socialist regime.
Dieses Nachschlagewerk bildet den Status quo des Controllings in
der Unternehmenspraxis ab. Verfasst von ausgewiesenen
Controlling-Spezialisten aus Wissenschaft und Wirtschaft werden
alle konzeptionellen Elemente dargestellt: Leitbild, Ziele,
Funktionen, Aufgaben, Instrumente, Prozesse und Effizienz. Anhand
der Wertschoepfungskette werden diese Konzepte fur verschiedene
Branchen, Unternehmenstypen und -groessen sowie
Eigentumerkonstellationen diskutiert. Mithilfe konkreter
Handlungsempfehlungen, Beispiele, Fallstudien und Interviews wird
das theoretische Fundament in die Praxis ubersetzt und die
Umsetzung im Unternehmen ermoeglicht.
Der Sammelband soll dazu beitragen, den Stellenwert von Serious
Games und Gamification als wichtige und nachhaltige Methode in der
beruflichen Aus- und Weiterbildung (Personalqualifikation,
Personalentwicklung) noch starker herauszuarbeiten. Gleichzeitig
sollen bedeutsame und zukunftsweisende Lernentwicklungsperspektiven
in digitalen Lernwelten aufgezeigt werden. Die enge Verknupfung von
didaktischen Aspekten und Lerneffekten, die aus dem praktischen
Einsatz von Serious Games resultieren koennen, grenzt die
Publikation von bislang vorliegenden Veroeffentlichungen zu dieser
Thematik ab, wie auch die Darstellung des praktischen Einsatzes der
Serious Games und deren Evaluation.
Stabilitatspolitische Fragen werden innerhalb der
Wirtschaftswissenschaften vorwiegend aus volkswirtschaftlicher
Sicht diskutiert. Im Rahmen der Betriebswirtschaftslehre sucht man
dagegen vergeblich nach einer intensiven Auseinandersetzung mit den
stabilitatspolitischen Aspekten des wirtschaftlichen Handelns.
Wolfgang Becker stellt unternehmenspolitische Konzepte zur
Sicherung der strategischen Handlungsfahigkeit vor. Ausgehend von
der Analyse stabilitatspolitischer Ziele, Strategien und
Instrumente zeigt der Autor auf, dass die Revision der
wettbewerbsstrategischen Orientierung von Unternehmen fur eine
geordnete Stabilitats- und Wachstumspolitik notwendig ist. Vor
diesem Hintergrund entwickelt der Autor seine ganzheitlich
orientierte Strategie der integrierten Kosten- und
Leistungsfuhrerschaft.
Verzeichnis: Der Autor stellt unternehmenspolitische Konzepte zur
Sicherung der strategischen Handlungsfahigkeit vor. Ausgehend von
der Analyse stabilitatspolitischer Ziele, Strategien und
Instrumente zeigt der Autor auf, dass die Revision der
wettbewerbsstrategischen Orientierung von Unternehmen fur eine
geordnete Stabilitats- und Wachstumspolitik notwendig ist. Vor
diesem Hintergrund entwickelt der Autor seine ganzheitlich
orientierte Strategie der integrierten Kosten- und
Leistungsfuhrerschaft."
Anlasslich des 60. Geburtstages von Wolfgang Mannel wurdigen
renommierte Fachvertreter aus Wissenschaft und Unternehmenspraxis
seinen Einfluss auf die Weiterentwicklung des internen
Rechnungswesens. Die Autoren geben einen zuverlassigen Einblick in
den derzeitigen Stand der Kostenrechnung und zeigen bedeutsame
Entwicklungsperspektiven auf.
Hochrangige Vertreter aus Wissenschaft und Praxis setzen sich aus
verschiedenen Blickwinkeln mit der Internationalisierung deutscher
kleiner und mittlerer Unternehmen auseinander. Sie prasentieren
dazu wegweisende Losungsmoglichkeiten auf dem Gebiet des
KMU-Managements. Neben einer aktualisierten Bestandsaufnahme bietet
die 2. Auflage einen fundierten Blick auf das Supply Chain
Management von KMU und enthalt Beitrage zum kennzahlengestutzten
Controlling sowie zum Mezzanine-Kapital.
Das Lexikon fur Beruf und Studium definiert mehr als 2.000
Stichworter zu Buchfuhrung, Bilanzierung, Kostenrechnung und
Controlling. Einfach und verstandlich werden die Grundlagen des
externen und internen Rechnungswesens erklart sowie die
Wechselwirkungen zwischen diesen Bereichen dargestellt.
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