A small informal symposium on "Molecular Genetics" was organized by us on behalf of the "Gesellschaft Deutscher Naturforscher und Arzte" and took place in Berlin in October 1967. There were about 40 partici pants from Europe and the United States. Molecular Genetics represents today an extraordinarily comprehensive research field. Therefore the organizers of the symposium had the choice either of limiting the meeting to a particular topic or of covering a wider selection of current problems. The latter alternative was chosen. The fields of research of the participants covered the broad range of scientific problems in which molecular genetics is nowadays involved: Genetic code; chemistry and biosynthesis of proteins; mutation, modification and reactivation of nucleic acids; biochemistry of regulation; comple mentation; structure; replication and function of viruses, etc. The meeting took place in the Hotel Schweizerhof where the partici pants were also accommodated. This permitted close contact between the participants outside of the official program and allowed informal discussions, which started during the meetings, to be continued after wards. Owing to the informal nature of these discussions, only a part of them could be included in this book. Berlin, September 1968 H. G. WITTMANN H. SCHUSTER Contents List of Participants . . . . . . . . . . .... VII I. Structure and Function of Ribosomes; Complementation Complementation and Dominance Relationsship between Protein Subunits. By J. R. S. FINCHAM. . . . . . . . . . . . . . . Ribosomal Proteins of E. coli and Yeast. By E. KALTSCHMIDT, V. RUDLOFF, G. STOFFLER, A. CHERSI, M. DZIONARA, D. DOl\IIER, and H. G. WITTMANN . . . . . . . . . . . . . . .. . . 5 ."

The various genera and species of the Orthopteran sub-family Tet- tigidae may be recognized under several names in the reports of a number of entomologists. They range from the form Bulla of LINNE (1767), whose figures are unmistakable, to the recent descriptions of SCUDDER (1900), HANCOCK (1902), and other orthoptologists. Such words as Tettix, Tettiginae and Tettigidae apparently were derived from "tettix" of Greek origin, meaning grasshopper. The common name, "Grouse locust", has probably been applied because of a fanci- ful resemblance of some of these insects to the grouse (Tetraoninae). B I 0 LOG Y 0 F THE GR 0 USE L 0 C U S T S The Distinguishing Characteristics. The following discussion con- cerning the characteristics which distinguish the Grouse Locusts is largely from the detailed descriptions by HANCOCK (1902) and Ro- BERTSON (1915). (See Fig. I). FIG. 1. Lateral, dorsal and frontal aspects of the body of a typical grouse locust, Acrydium (From HANCOCK) They are among the smallest of the Orthoptera. The extremely de- veloped apical process of the pronotum extends backward over the 30 THE GENETICS OF THE TETTIGIDAE (GROUSE LOCUSTS) Explanation of Plate I (All figures from HANCOCK, 1902) FIG. 1. Choriphyllum /oliatum HANCOCK. Female from Jamaica. FIG. 2. Nymph of Acrydium obscurus HANCOCK. FIG. 3. Tettigidea parvipennis preparing the burrow for the eggs. FIG. 4. Acrydium granulatus SCUDDER. Female. FIG. 5 and 6. Dorsal and profile views of posterior abdominal appen- dages of a male Acrydium hancocki MORSE.

Providing a review of the recent advances and technologies in the rapidly expanding field of genetics, embryology and molecular biology, this book also investigates the possibilities for future research and development. There are sections covering manipulation of the embryo, and the mapping and engineering of the genome. Topics discussed range from nuclear transfer to the possibilities and techniques involved in the development of xenotransplantation.

Involvement with equine reproduction is very common for the veterinarian in practice, and there is enormous demand for continuing education, particularly in the light of recent changes in science and practice, such as the routine use of ultrasound, improved standards of foal care, and the importance of artificial insemination. The 22 contributing authors, an international blend of specialist equine practitioners and university clinicians, provide by means of superbly illustrated questions and full explanatory answers, a comprehensive, up-to-date, enjoyable and easily read source of information on equine reproduction. Over 30 cases concern the use of ultrasound in the management of the broodmare, some 50 cases cover foal care and common medical /surgical conditions, and there are over 30 cases on the stallion and artificial insemination, plus rarer conditions such as dystocia and foaling trauma. The random order of the cases and the self-assessment format, enable readers to think fully about a problem and devise a solution, just as they would in their daily work. The book appeals equally to veterinarians in training, in practice and in preparation for higher qualifications.

Widespread across open lands and cities of Europe, Africa, and Asia, the common kestrel (Falco tinnunculus) is one of the most abundant and studied birds of prey. This book brings together and synthesises the results of research on kestrels for professional ornithologists and scientists that seek to consolidate a vast body of literature. It is also a reference for those readers who may not have the depth of scientific knowledge to navigate new fields of scientific enquiry. It examines many aspects of the species' biology, from the reproductive strategies to the behavioural and demographic adaptations to changes of environmental conditions. It also discusses the roles of physiology and immunology in mediating the adaptability of kestrels to the ongoing environmental changes with a particular focus on contaminants. This volume presents new and exciting avenues of research on the ecology and behaviour of the common kestrel.

Life histories can be defined as the means by which individuals (or more precisely genotypes) vary their age- or stage-specific expenditures of reproductive effort in response to genetic, phenotypic, and environmental correlates of survival and fecundity. Life histories reflect the expression of traits most closely related to individual fitness, such as age and size at maturity, number and size of offspring, and the timing of the expression of those traits throughout an individual's life. In addition to addressing questions of fundamental importance to ecology and evolution, life-history research plays an integral role in species conservation and management. This accessible primer encompasses the basic concepts, theories, and applied elements of life history evolution, including patterns of trait variability, underlying mechanisms of plastic/evolutionary change, and the practical utility of life-history traits as metrics of species/population recovery, sustainable exploitation, and risk of extinction. Empirical examples are drawn from the entire spectrum of life. A Primer of Life Histories is designed for readers from a broad range of academic backgrounds and experience including graduate students and researchers of ecology and evolutionary biology. It will also be useful to a more applied audience of academic/government researchers in fields such as wildlife biology, conservation biology, fisheries science, and the environmental sciences.

Insects display a staggering diversity of mating and social behaviours. Studying these systems provides insights into a wide range of evolutionary and behavioural questions, such as the evolution of sex, sexual selection, sexual conflict, and parental care. This edited volume provides an authoritative update of the landmark book in the field, The Evolution of Insect Mating Systems (Thornhill and Alcock, 1983), which had such a huge impact in shaping adaptationist approaches to the study of animal behaviour and influencing the study of the evolution of reproductive behaviour far beyond the taxonomic remit of insects. This accessible new volume brings the empirical and conceptual scope of the original book fully up to date, incorporating the wealth of new knowledge and research of the last 30 years. It explores the evolution of complex forms of sex determination in insects, and the role of sexual selection in shaping the evolution of mating systems. Selection arising via male contest competition and female choice (both before and after copulation) are discussed, as are the roles of parasites and pathogens in mediating the strength of sexual selection, and the role that parental care plays in successful reproduction. The Evolution of Insect Mating Systems is suitable for both graduate students and researchers interested in insect mating systems or behaviour from an evolutionary, genetical, physiological, or ecological perspective. Due to its interdisciplinary and concept-driven approach, it will also be of relevance and use to a broad audience of evolutionary biologists.

Insects display a staggering diversity of mating and social behaviours. Studying these systems provides insights into a wide range of evolutionary and behavioural questions, such as the evolution of sex, sexual selection, sexual conflict, and parental care. This edited volume provides an authoritative update of the landmark book in the field, The Evolution of Insect Mating Systems (Thornhill and Alcock, 1983), which had such a huge impact in shaping adaptationist approaches to the study of animal behaviour and influencing the study of the evolution of reproductive behaviour far beyond the taxonomic remit of insects. This accessible new volume brings the empirical and conceptual scope of the original book fully up to date, incorporating the wealth of new knowledge and research of the last 30 years. It explores the evolution of complex forms of sex determination in insects, and the role of sexual selection in shaping the evolution of mating systems. Selection arising via male contest competition and female choice (both before and after copulation) are discussed, as are the roles of parasites and pathogens in mediating the strength of sexual selection, and the role that parental care plays in successful reproduction. The Evolution of Insect Mating Systems is suitable for both graduate students and researchers interested in insect mating systems or behaviour from an evolutionary, genetical, physiological, or ecological perspective. Due to its interdisciplinary and concept-driven approach, it will also be of relevance and use to a broad audience of evolutionary biologists.

The intended audience of this textbook are plant and animal breeders, upper-level undergraduate and graduate students in biological and agricultural science majors. Statisticians who are interested in understanding how statistical methods are applied to genetics and agriculture can benefit substantially by reading this book. One characteristic of this textbook is represented by three chapters of technical reviews for Mendelian genetics, population genetics and preliminary statistics, which are prerequisites for studying quantitative genetics. Numerous examples are provided to illustrate different methods of data analysis and estimation of genetic parameters. Along with each example of data analyses is the program code of SAS (statistical analysis system).

This book adopts an experimental approach to understanding the mechanisms of evolution and the nature of evolutionary processes, with examples drawn from microbial, plant and animal systems. It incorporates insights from remarkable recent advances in theoretical modeling, and the fields of molecular genetics and environmental genomics.
Adaptation is caused by selection continually winnowing the genetic variation created by mutation. In the last decade, our knowledge of how selection operates on populations in the field and in the laboratory has increased enormously, and the principal aim of this book is to provide an up-to-date account of selection as the principal agent of evolution. In the classical Fisherian model, weak selection acting on many genes of small effect over long periods of time is responsible for driving slow and gradual change. However, it is now clear that adaptation in laboratory populations often involves strong selection acting on a few genes of large effect, while in the wild selection is often strong and highly variable in space and time. Indeed these results are changing our perception of how evolutionary change takes place. This book summarizes our current understanding of the causes and consequences of selection, with an emphasis on quantitative and experimental studies. It includes the latest research into experimental evolution, natural selection in the wild, artificial selection, selfish genetic elements, selection in social contexts, sexual selection, and speciation.
Selection: The Mechanism of Evolution is an advanced textbook suitable for senior undergraduate and graduate students taking courses in evolutionary biology, ecology, populationgenetics, and experimental evolution. It will also be a valuable reference tool for those professional researchers in these fields requiring an authoritative and up-to-date overview of the topic, as well as providing an accessible treatment of evolutionary mechanisms for molecular and cellular biologists.

This book is open access under a CC BY 4.0 license This open access book brings together the latest genome base prediction models currently being used by statisticians, breeders and data scientists. It provides an accessible way to understand the theory behind each statistical learning tool, the required pre-processing, the basics of model building, how to train statistical learning methods, the basic R scripts needed to implement each statistical learning tool, and the output of each tool. To do so, for each tool the book provides background theory, some elements of the R statistical software for its implementation, the conceptual underpinnings, and at least two illustrative examples with data from real-world genomic selection experiments. Lastly, worked-out examples help readers check their own comprehension.The book will greatly appeal to readers in plant (and animal) breeding, geneticists and statisticians, as it provides in a very accessible way the necessary theory, the appropriate R code, and illustrative examples for a complete understanding of each statistical learning tool. In addition, it weighs the advantages and disadvantages of each tool.

This book is a practical guide for biologists who use multiple sequence alignments (MSAs) for their data analysis and are looking for a comprehensive overview of the many different programs. Despite their important role in data analysis, there is uncertainty among researchers about exactly how MSA programs work - not to mention how and why the different analyzes lead to different results. Which program is the right one for evaluating my data and how can I ensure that I have drawn all relevant findings from the alignments? This book offers helpful explanations and background information without requiring extensive bioinformatics knowledge and slowly introduces the reader to the topic.In the first part of the book, the possible fields of application as well as the formats that are usually produced by MSA programs are described in detail. The central algorithms as well as the internal processes of the most common MSA programs of the past and the present are also explained in an uncomplicated manner in greater detail. The second part of the book is a detailed, data-based comparison between MSA programs, which is intended to help you decide which program to use for your next alignment.

The first volume in the new Cambridge Handbooks in Behavioral Genetics series, Behavioral Genetics of the Mouse provides baseline information on normal behaviors, essential in both the design of experiments using genetically modified or pharmacologically treated animals and in the interpretation and analyses of the results obtained. The book offers a comprehensive overview of the genetics of naturally occurring variation in mouse behavior, from perception and spontaneous behaviors such as exploration, aggression, social interactions and motor behaviors, to reinforced behaviors such as the different types of learning. Also included are numerous examples of potential experimental problems, which will aid and guide researchers trying to troubleshoot their own studies. A lasting reference, the thorough and comprehensive reviews offer an easy entrance into the extensive literature in this field, and will prove invaluable to students and specialists alike.

Reproduction is a fundamental feature of life, it is the way life persists across the ages. This book offers new, wider vistas on this fundamental biological phenomenon, exploring how it works through the whole tree of life. It explores facets such as asexual reproduction, parthenogenesis, sex determination and reproductive investment, with a taxonomic coverage extended over all the main groups - animals, plants including 'algae', fungi, protists and bacteria. It collates into one volume perspectives from varied disciplines - including zoology, botany, microbiology, genetics, cell biology, developmental biology, evolutionary biology, animal and plant physiology, and ethology - integrating information into a common language. Crucially, the book aims to identify the commonalties among reproductive phenomena, while demonstrating the diversity even amongst closely related taxa. Its integrated approach makes this a valuable reference book for students and researchers, as well as an effective entry point for deeper study on specific topics.

This book describes the biological basis of reproduction in poultry and places this information in the context of poultry production. The author has collated and integrated recent information from a variety of sources in order to highlight the principles of the reproductive biology of poultry. This is achieved through a well-illustrated and tabulated text which emphasizes integration rather than comprehensive literature citations. The book begins by considering the egg, proceeds to a brief description of embryonic and chick development as they relate to poultry production, and describes the physiological processes that lead to formation of the fertile egg. It concludes with a discussion of the relationship between measurements of reproductive success that are commonly used in the poultry industry and their ability to reflect the physiological processes that contribute to successful reproduction. The book is aimed at advanced undergraduates or graduate students studying animal reproduction or agriculture, as well as scientists working in the poultry industry.

Cooperative breeders are species in which individuals beyond a pair assist in the production of young in a single brood or litter. Although relatively rare, cooperative breeding is widespread taxonomically and continues to pose challenges to our understanding of the evolution of cooperation and altruistic behavior. Bringing together long-term studies of cooperatively breeding birds, mammals, and fish, this volume provides a synthesis of current studies in the field. The chapters are organised by individual studies of particular species or (in the case of mole-rats) two closely related cooperatively breeding species. Each focuses not only on describing behavior and ecology but also on testing evolutionary hypotheses for the form and function of the diverse and extraordinary cooperative breeding lifestyles that have been discovered. This unique and comprehensive text will be of interest to graduate students and researchers of behavioral ecology and the evolution of cooperation.

Originally published in 1934 as part of the Cambridge Comparative Physiology series, this book discusses the process of tissue differentiation in developing embryos of a variety of species. Huxley and de Beer examine important aspects of development such as symmetry, the mosaic stage of differentiation and the relationship between hereditary factors and differentiation. This book will be of value to anyone with an interest in the history of science or embryology.

This book provides the Assisted Reproduction Technologies (ART) community an update of the fast approaching novel technologies that may allow improved assessment of the reproductive potential of sperm, oocytes and embryos. The reader has access to concise updates on the rapidly developing diagnostic technologies (genomics, transcriptomics, proteomics and metabolomics) and morphological methods which may help us better assess the gametes and embryos. Methodologies are described which enable selection of the best gamete or embryo by invasive and non-invasive diagnostics, as well as the clinical validity of these techniques.

This publication contains the proceedings of a seminar held in Brussels on November 8-9, 1988. The title of the seminar was "Reducing the costs of disease by improving resistance through genetics." The seminar was held as an activity of the Community Programme for the Coordination of Agricultural Research, 1984-1988. Costs of disease depend on losses caused by morbidity, mortality and production decreases and on the costs of preventive measures including vaccination and medication. Production losses often contribute a major portion to the total costs. To reduce costs of disease preventive measures like vaccination, preventive medication and hygienic procedures are applied. Genetic resistance is an attractive preventive measure because of its consistent nature in the next generations, because it precludes veterinary services and because there are no side-effects. Constraints are the long term investment, relatively slow progress per generation (in combination with production traits) and the considerable lack of knowledge about inheritance of resistance mechanisms in farm animals.