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Books > Science & Mathematics > Biology, life sciences > Zoology & animal sciences > Animal reproduction

Fluorescence in situ Hybridization (FISH) - Protocols and Applications (Hardcover, 2010): Joanna M. Bridger, Keith Morris Fluorescence in situ Hybridization (FISH) - Protocols and Applications (Hardcover, 2010)
Joanna M. Bridger, Keith Morris
R4,490 Discovery Miles 44 900 Ships in 10 - 15 working days

Fluorescence in situ Hybridization (FISH) belongs to that special category of well-established molecular biology techniques that, since their inception a few decades ago, have succeeded in keeping a prominent position within the constantly expanding list of laboratory pro- dures for biomedical research and clinical diagnostics. The design simplicity and cost-effectiveness of the early FISH protocols, combined with the signifcant acceleration of discoveries in related technical areas such as fuor- cence microscopy, digital imaging, and nucleic acid technology have prompted the div- sifcation of the original technique into an outstanding number of imaginative and useful applications, and thus have not only held back its outmoding but have also promoted its expansion into different areas of basic and applied research in the post-genomic era. The 34 chapters included in this book aim at portraying the vibrant complexity and diversity of the current FISH protocol landscape, providing cutting-edge examples of va- ous applications for genetic and developmental research, cancer research, reproductive medicine, diagnostic and prognostic purposes, microbial ecology, and evolutionary st- ies. The book is divided in four parts: (I) Core Techniques, (II) Technical Advancements and Novel Adaptations, (III) Translational FISH: Applications for Human Genetics and Medicine, and (IV) Protocols for Model Organisms.

A Handbook of Gene and Cell Therapy (Hardcover, 1st ed. 2020): Clevio Nobrega, Liliana Mendonca, Carlos A. Matos A Handbook of Gene and Cell Therapy (Hardcover, 1st ed. 2020)
Clevio Nobrega, Liliana Mendonca, Carlos A. Matos
R4,586 Discovery Miles 45 860 Ships in 12 - 19 working days

This is a reference handbook for young researchers exploring gene and cell therapy. Gene therapy could be defined as a set of strategies modifying gene expression or correcting mutant/defective genes through the administration of DNA (or RNA) to cells, in order to treat disease. Important advances like the discovery of RNA interference, the completion of the Human Genome project or the development of induced pluripotent stem cells (iPSc) and the basics of gene therapy are covered. This is a great book for students, teachers, biomedical researchers delving into gene/cell therapy or researchers borrowing skills from this scientific field.

Progestins and the Mammary Gland - From Basic Science to Clinical Applications (Hardcover, 2008 ed.): Orla M. Conneely,... Progestins and the Mammary Gland - From Basic Science to Clinical Applications (Hardcover, 2008 ed.)
Orla M. Conneely, Christiane Otto
R2,882 Discovery Miles 28 820 Ships in 10 - 15 working days

Progestins play a key role in reproductive endocrinology and as pharmaceutical drugs for contraception and in combined hormone therapy. To further our understanding of progestin action in the mammary gland, an international symposium, attended by leading researchers from academia and industry, was held in Berlin, 21 23 March 2007. Genetic mouse models helped to elucidate the role of progestins, both in normal breast development and in disease. Mechanistic molecular studies inspired the design of new progestins with improved tissue selectivity. In addition, the clinical impact of progesterone receptor agonists and antagonists for the prevention and treatment of breast cancer was discussed.

Insect Hearing and Acoustic Communication (Hardcover, 2014 ed.): Berthold Hedwig Insect Hearing and Acoustic Communication (Hardcover, 2014 ed.)
Berthold Hedwig
R7,156 Discovery Miles 71 560 Ships in 10 - 15 working days

This volume provides a comprehensive selection of recent studies addressing insect hearing and acoustic communication. The variety of signalling behaviours and hearing organs makes insects highly suitable animals for exploring and analysing signal generation and hearing in the context of neural processing, ecology, evolution and genetics. Across a variety of hearing species like moths, crickets, bush-crickets, grasshoppers, cicadas and flies, the leading researchers in the field cover recent scientific progress and address key points in current research, such as:

. How can we approach the evolution of hearing in insects and what is the developmental and neural origin of the auditory organs?

. How are hearing and sound production embedded in the natural lifestyle of the animals, allowing intraspecific communication but also predator avoidance and even predation?

. What are the functional properties of hearing organs and how are they achieved at the molecular, biophysical and neural levels?

. What are the neural mechanisms of central auditory processing and signal generation?

The book is intended for students and researchers both inside and outside of the fascinating field of bioacoustics and aims to foster understanding of hearing and acoustic communication in insects."

Transgenic Mouse Methods and Protocols (Hardcover, 2nd ed. 2011): Marten H. Hofker, Jan Van Deursen Transgenic Mouse Methods and Protocols (Hardcover, 2nd ed. 2011)
Marten H. Hofker, Jan Van Deursen
R5,661 Discovery Miles 56 610 Ships in 10 - 15 working days

The generation of genetically modified mice is absolutely crucial to gene function studies today, primarily because mice are genetically similar to man and because gene function studies in mice are in the context of a whole organism, making them particularly useful. In Transgenic Mouse Methods and Protocols, Second Edition, expert research explore current advances in the field through detailed laboratory protocols. Chapters provide a general introduction outlining how to deal with mice and how to generate transgenic mouse models, explore the generation of conditional and induced knockout and transgenic mice, and offer alternative routes to studying gene function in mice. Composed in the highly successful Methods in Molecular Biology (TM) series format, each chapter contains a brief introduction, step-by-step methods, a list of necessary materials, and a Notes section which shares tips on troubleshooting and avoiding known pitfalls. Comprehensive and state of the art, Transgenic Mouse Methods and Protocols, second Edition is the ideal guide for all researchers interested in the latest information about the production and analysis of transgenic and knockout mice.

Problematic Wildlife - A Cross-Disciplinary Approach (Hardcover, 1st ed. 2016): Francesco M Angelici Problematic Wildlife - A Cross-Disciplinary Approach (Hardcover, 1st ed. 2016)
Francesco M Angelici
R4,532 Discovery Miles 45 320 Ships in 10 - 15 working days

This book provides insight into the instances in which wildlife species can create problems. Some species trigger problems for human activities, but many others need humans to save them and to continue to exist. The text addresses issues faced by economists and politicians dealing with laws involving actions undertaken to resolve the problems of the interaction between humans and wildlife. Here, the words 'problematic species' are used in their broadest sense, as may be appreciated in the short introductions to the various sections. At times, the authors discuss special cases while always extending the discussion into a more general and broad vision. At others, they present real cutting-edge analysis of ecological topics and issues. The book will be of interest to biologists, ecologists and wildlife managers involved in research on wildlife, parks, and environmental management, as well as to government departments and agencies, NGOs and conservation wildlife organizations. Even those in contact with nature, such as hunters, herders, and farmers, will be able to find a great deal of important information. Specific case studies are selected from among the most significant and prevalent cases throughout the world. A total of 26 papers have been selected for this book, written by zoologists, biologists and ecologists. Many have an interdisciplinary approach, with contributions by economists, criminologists, technical specialists, and engineers.

Genetic Resources of Neotropical Fishes (Hardcover, 1st ed. 2017): Alexandre W. S. Hilsdorf, Eric M. Hallerman Genetic Resources of Neotropical Fishes (Hardcover, 1st ed. 2017)
Alexandre W. S. Hilsdorf, Eric M. Hallerman
R4,954 Discovery Miles 49 540 Ships in 12 - 19 working days

The aim of this book is to systematize and discuss population genetic studies of freshwater fish in a region that harbors the greatest diversity of species among all inland water ecosystems. This volume explores the genetic evaluation for a number of orders, families and species of Neotropical fishes, and provides an overview on genetic resources and diversity and their relationships with fish domestication, breeding, and food production.

DNA Barcoding in Marine Perspectives - Assessment and Conservation of Biodiversity (Hardcover, 1st ed. 2016): Subrata Trivedi,... DNA Barcoding in Marine Perspectives - Assessment and Conservation of Biodiversity (Hardcover, 1st ed. 2016)
Subrata Trivedi, Abid Ali Ansari, Sankar K. Ghosh, Hasibur Rehman
R5,032 Discovery Miles 50 320 Ships in 12 - 19 working days

More than two third of the surface area of our planet is covered by oceans and assessment of the marine biodiversity is a challenging task. With the increasing global population, there is a tendency to exploit marine recourses for food, energy and other requirements. This puts pressure on the fragile marine environment and needs sustainable conservation efforts. Marine species identification using traditional taxonomical methods are often burdened with taxonomic controversies. Here in this book we will discuss the comparatively new concept of DNA barcoding and its significance in marine perspective. This molecular technique can be helpful in the assessment of cryptic species which are widespread in marine environment, and can also be used to link the different life cycle stages to the adult which is difficult to accomplish in marine ecosystems. Other advantages of DNA barcoding include authentication and safety assessment of seafood, wildlife forensics, conservation genetics and detection of invasive alien species (IAS). Global DNA barcoding efforts in the marine habitat include MarBOL, CeDAMar, CMarZ, SHARK-BOL, etc. DNA barcoding of different marine groups ranging from the microbes to mammals is to be revealed. In conjugation with newer and faster techniques like high throughput sequencing, DNA barcoding is serving as an effective modern tool in marine biodiversity assessment and conservation.

Stem Cells & Regenerative Medicine - From Molecular Embryology to Tissue Engineering (Hardcover, Edition.): Krishnarao... Stem Cells & Regenerative Medicine - From Molecular Embryology to Tissue Engineering (Hardcover, Edition.)
Krishnarao Appasani, Raghu K Appasani
R8,418 Discovery Miles 84 180 Ships in 10 - 15 working days

Defined as, "The science about the development of an embryo from the fertilization of the ovum to the fetus stage," embryology has been a mainstay at universities throughout the world for many years. Throughout the last century, embryology became overshadowed by experimental-based genetics and cell biology, transforming the field into developmental biology, which replaced embryology in Biology departments in many universities. Major contributions in this young century in the fields of molecular biology, biochemistry and genomics were integrated with both embryology and developmental biology to provide an understanding of the molecular portrait of a "development cell." That new integrated approach is known as stem-cell biology; it is an understanding of the embryology and development together at the molecular level using engineering, imaging and cell culture principles, and it is at the heart of this seminal book. Stem Cells and Regenerative Medicine: From Molecular Embryology to Tissue Engineering is completely devoted to the basic developmental, cellular and molecular biological aspects of stem cells as well as their clinical applications in tissue engineering and regenerative medicine. It focuses on the basic biology of embryonic and cancer cells plus their key involvement in self-renewal, muscle repair, epigenetic processes, and therapeutic applications. In addition, it covers other key relevant topics such as nuclear reprogramming induced pluripotency and stem cell culture techniques using novel biomaterials. A thorough introduction to stem-cell biology, this reference is aimed at graduate students, post-docs, and professors as well as executives and scientists in biotech and pharmaceutical companies.

Bemisia: Bionomics and Management of a Global Pest (Hardcover, 2010 Ed.): Philip A. Stansly, Steven E. Naranjo Bemisia: Bionomics and Management of a Global Pest (Hardcover, 2010 Ed.)
Philip A. Stansly, Steven E. Naranjo
R5,704 Discovery Miles 57 040 Ships in 10 - 15 working days

Bemisia tabaci (Gennedius) has distinguished itself from the more than 1,000 whitefly species in the world by its adaptability, persistence and potential to damage a wide range of agricultural and horticultural crops in all six of the world s inhabited continents. B. tabaci inflicts plant damage through direct feeding, inducement of plant disorders, vectoring of plant viruses and excretion of honeydew. This book collates multiple aspects of the pest ranging from basic to applied science and molecular to landscape levels of investigation. Experts in multiple disciplines provide broad, but detailed summaries and discussion of taxonomy, genetics, anatomy, morphology, physiology, behavior, ecology, symbiotic relationships, virus vector associations and various tactics for integrated management of this pest insect. The book is focused primarily on progress during the last 10-15 years and is directed at workers in the field as well as the informed professional who may not necessarily specialize in whitefly research. The book is unique in providing broad coverage in relatively few chapters by recognized experts that highlight the state-of-the-art in our understanding of this fascinating but troublesome cosmopolitan pest."

GnRH: The Master Molecule of Reproduction (Hardcover, 2002 ed.): Andrea C. Gore GnRH: The Master Molecule of Reproduction (Hardcover, 2002 ed.)
Andrea C. Gore
R5,781 Discovery Miles 57 810 Ships in 10 - 15 working days

Gonadotropin-releasing hormone (GnRH) cells are the key regulators of reproductive function in all vertebrate organisms. The GnRH molecule is synthesized in a small number of neurons in rostral hypothalamic regions of the brain. In mammals, these neurons release the GnRH decapeptide into the portal capillary system leading to the anterior pituitary gland. There, GnRH causes the release of the gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which in turn act upon the gonads to stimulate their maturation, and to cause synthesis of sex steroid hormones, estrogen, progesterone and testosterone. Although each of the levels of the hypothalamic-pituitary-gonadal axis is critical for reproductive function, GnRH neurons play the primary role in the control of reproductive maturation and adult reproductive function, and may even play a role in reproductive senescence.

Since its discovery in 1970, there has been intense interest in GnRH-producing neurons, with more than 8000 papers and chapters in the last decade alone. Despite this activity of research in basic and clinical science, there has never been a book written specifically on GnRH neurons. GnRH: The Master Molecule of Reproduction aims to bring together the large and diverse literature of both laboratory and applied research that focuses on these unique cells.

This book will provide basic background into reproductive neuroendocrinology, as well as specifics regarding the role of GnRH neurons in the control of reproduction. Students studying endocrinology, reproduction, neuroendocrinology or molecular endocrinology will benefit from this book. In addition, this book will take a multi-species approach which will be useful both to basic researchers as well as clinicians. Whenever possible, species differences and similarities will be presented, and if possible, studies on humans, or the clinical relevance of basic research findings to humans will be discussed (such as the treatment of reproductive disorders such as abnormalities in pubertal development, or infertility).

Metamorphosis - Postembryonic Reprogramming of Gene Expression in Amphibian and Insect Cells (Hardcover): Lawrence I. Gilbert,... Metamorphosis - Postembryonic Reprogramming of Gene Expression in Amphibian and Insect Cells (Hardcover)
Lawrence I. Gilbert, Jamshed R. Tata, Burr G. Atkinson
R4,875 Discovery Miles 48 750 Ships in 12 - 19 working days

Metamorphosis addresses various facets of postembryonic development, particularly signal transduction, morphogenesis, cell-cell interactions, and programmed cell death. A key feature of the book is its exploration of the molecular mechanisms underlying these processes.
Key Features
* Hormonal regulation of development
* The mechanisms of hormone action
* The steroid/thyroid hormone receptor family
* Morphogenesis and programmed cell death

Sequence - Evolution - Function - Computational Approaches in Comparative Genomics (Hardcover, 2003 ed.): Eugene V. Koonin,... Sequence - Evolution - Function - Computational Approaches in Comparative Genomics (Hardcover, 2003 ed.)
Eugene V. Koonin, Michael Galperin
R4,206 Discovery Miles 42 060 Ships in 10 - 15 working days

Sequence - Evolution - Function is an introduction to the computational approaches that play a critical role in the emerging new branch of biology known as functional genomics. The book provides the reader with an understanding of the principles and approaches of functional genomics and of the potential and limitations of computational and experimental approaches to genome analysis.

Key topics covered in this textbook are:
*the completed and ongoing genome sequencing projects,
*databases that store and organize genomic data, with their unique advantages and pitfalls,
*principles and methods of genome analysis and annotation,
*ways to automate the searches and increase search sensitivity while minimizing the error rate,
*the first lessons from the Human Genome Project,
*the contribution of comparative genomics to the understanding of hereditary diseases and cancer,
*fundamental and practical applications of comparative genomics,
*the use of complete genomes for evolutionary analysis,
*the application of comparative genomics for identification of potential drug targets in microbial genomes,
*Problems for Further Study, which are designed to be solved by using methods available through the WWW. Sequence - Evolution - Function should help bridge the "digital divide" between biologists and computer scientists, allowing biologists to better grasp the peculiarities of the emerging field of Genome Biology and to learn how to benefit from the enormous amount of sequence data available in the public databases. The book is non-technical with respect to the computer methods for genome analysis and discusses these methods from the user's viewpoint, without addressing mathematical and algorithmic details. Prior practical familiarity with the basic methods for sequence analysis is a major advantage, but a reader without such experience will be able to use the book as an introduction to these methods. This book is perfect for introductory level courses in computational methods for comparative and functional genomics.

Mouse as a Model Organism - From Animals to Cells (Hardcover, 2011 ed.): Cord Brakebusch, Taina Pihlajaniemi Mouse as a Model Organism - From Animals to Cells (Hardcover, 2011 ed.)
Cord Brakebusch, Taina Pihlajaniemi
R4,346 Discovery Miles 43 460 Ships in 10 - 15 working days

Cell culture based research is important for our understanding of biological processes at the cellular and molecular level. Using this approach, the previous decades have produced a wealth of mechanistic information in all areas of biomedical research. Such in vitro research, however, lacks the complexity of in vivo investigations, where many different cell types interact with each other in a normal, three-dimensional environment, with normal levels of cytokines and growth factors. Furthermore, complex human diseases, such as cancer, diabetes or chronic inflammation, can only be modeled in vivo. Due to its small size, its short reproduction time, and the possibility to introduce specific gene mutations, the mouse has become the favourite mammalian model organism to study in vivo function of genes during development and in disease. This book combines review articles on selected subjects presented at the symposium "Mouse as a Model Organism - From Animals to Cells", held in Rovaniemi, Finland, 2009. Among other topics, high-throughput phenotyping of mouse mutants, mouse phenotypes dependent on nature and nuture, and a spectrum of in vivo, ex vivo and in vitro methods to study cancer in mice are described. This book will give an excellent introduction to scientists interested in the use of mice as a model to understand complex biological questions in the post-genomic era. It will highlight the possibilities, but also discuss the current problems and shortcomings, to give a realistic view of the current state-of-art in this fascinating field of biomedical research.

Short Views on Insect Genomics and Proteomics - Insect Genomics, Vol.1 (Hardcover, 1st ed. 2015): Chandrasekar Raman, Marian R.... Short Views on Insect Genomics and Proteomics - Insect Genomics, Vol.1 (Hardcover, 1st ed. 2015)
Chandrasekar Raman, Marian R. Goldsmith, Tolulope A. Agunbiade
R4,676 R3,531 Discovery Miles 35 310 Save R1,145 (24%) Ships in 12 - 19 working days

Entomology as a science of inter-depended branches like molecular entomology, insect biotechnology, has made rapid progress. This also implies that there is an urgent need to manage the available resources. In the past five decades, entomology has taken giant steps ahead. The aim of this work is to integrate perspectives across molecular and biochemistry, physiology, reproduction, developmental biology, molecular evolution, genetics and RNAi applications. This century is proclaimed as the Era of Biotechnology and it consists of all types of Mol-Bio-Gen applications, which is an essential component for a thorough understanding of the insect biology. The aim of this work is to provide the comprehensive review of recent research from various geographic areas around the world and contributing authors that are recognized experts in their respective field of Genomic entomology. This Volume emphasizes upon the need for and relevance of studying molecular aspects of entomology in Universities, Agricultural Universities and other centers of molecular research. It will also serve as a landmark source for Insect advance science technology.

Pregnancy and Parturition, Volume 1 (Hardcover): T. Zakar Pregnancy and Parturition, Volume 1 (Hardcover)
T. Zakar
R3,372 Discovery Miles 33 720 Ships in 12 - 19 working days

One of the mysteries of mammalian reproduction is the physiologic process that determines the length of gestation. The proper timing of birth ensures that the young individual is sufficiently developed to survive and adapt in the extrauterine environment, and that the mother is capable to provide nutrition and protection to the newborn. This volume summarizes new knowledge obtained by many researchers seeking to unravel the compile mechanisms that contribute to the maintenance and termination of pregnancy. The most important common goal of these efforts is to reduce the incidence of preterm birth, which is the leading cause of perinatal morbidity and mortality in numerous countries.
Separate chapters are devoted to the best-studied animal models of parturition. In sheep, the fetus is in control of the timing of its own birth, while in avian species, oviposition is evidently determined by the female laying the feritlized egg. In humans and non-human primates, the roles of the fetus and the mother are more balanced, and involve a complicated and poorly understood interplay between the mother, the fetus, and the placenta. Some major aspects of these interactions, such as trophoblast function, myometrial contractility, and the endocrine-paracrine systems, are discussed in further chapters.

The Genetic Basis of Male Infertility (Hardcover, 2000 ed.): Ken McElreavey The Genetic Basis of Male Infertility (Hardcover, 2000 ed.)
Ken McElreavey
R5,761 Discovery Miles 57 610 Ships in 10 - 15 working days

Every year there are new and exciting developments in assisted human reproduction, but how much do we really know about the underlying causes of infertility? This volume explores recent progress in the understanding of the genetics of spermatogenesis and male infertility. Topics include fundamental advances and current problems in the development and function of the testis, an outline of clinical findings in male infertility and an overview of the role of the Y chromosome in male fertility. Comprehensive critiques of posttranscriptional control during spermatogenesis, mammalian meiotic sterility, and comparative genetics of human spermatogenesis from the perspective of yeast, "Drosophila" and mice provide a global overview of the field.

Evolutionary Biology - Concepts, Molecular and Morphological Evolution (Hardcover, 2010 ed.): Pierre Pontarotti Evolutionary Biology - Concepts, Molecular and Morphological Evolution (Hardcover, 2010 ed.)
Pierre Pontarotti
R6,384 Discovery Miles 63 840 Ships in 10 - 15 working days

The annual Evolutionary Biology Meetings in Marseille aim to bring together leading scientists, promoting an exchange of state-of-the-art knowledge and the formation of inter-group collaborations. This book presents the most representative contributions to the 13th meeting, which was held in September 2009. It comprises 21 chapters, which are organized into the following three categories: * Evolutionary Biology Concepts * Genome/Molecular Evolution * Morphological Evolution/Speciation This book offers an up-to-date overview of evolutionary biology concepts and their use in the biology of the 21st century.

Genetic Engineering in Livestock - New Applications and Interdisciplinary Perspectives (Hardcover, 2009 ed.): Margret... Genetic Engineering in Livestock - New Applications and Interdisciplinary Perspectives (Hardcover, 2009 ed.)
Margret Engelhard, Kristin Hagen, Matthias Boysen
R1,521 Discovery Miles 15 210 Ships in 10 - 15 working days

Upcoming applications of genetic engineering in farm animals include higher yields, leaner meat, or disease resistance. The proceedings cover an analysis of the state of the art of the technology and its applications, an introduction to the specific application zoopharming (a method to produce biopharmaceuticals in transgenic livestock), including an analysis of the market for biopharmaceuticals. In addition an assessment of ethical aspects of livestock biotechnology and considerations regarding animal welfare implications are covered. The study is addressed to science, industry and politics.

Evolutionary Biology - Convergent Evolution, Evolution of Complex Traits, Concepts and Methods (Hardcover, 1st ed. 2016):... Evolutionary Biology - Convergent Evolution, Evolution of Complex Traits, Concepts and Methods (Hardcover, 1st ed. 2016)
Pierre Pontarotti
R5,142 Discovery Miles 51 420 Ships in 12 - 19 working days

This book presents selected contributions to the 19th Evolutionary Biology Meeting, which took place in September 2015 in Marseille. It consists of 22 chapters, which are grouped in four sections: * Convergent Evolution * Evolution of Complex Traits * Concepts * Methods The annual Evolutionary Biology Meetings in Marseille serve to gather leading evolutionary biologists and other scientists using evolutionary biology concepts, e.g for medical research, to promote the exchange of ideas and to encourage interdisciplinary collaborations. Offering an up-to-date overview of recent findings in the field of evolutionary biology, this book is an invaluable source of information for scientists, teachers and advanced students.

Targeted Genome Editing Using Site-Specific Nucleases - ZFNs, TALENs, and the CRISPR/Cas9 System (Hardcover, 2015 ed.): Takashi... Targeted Genome Editing Using Site-Specific Nucleases - ZFNs, TALENs, and the CRISPR/Cas9 System (Hardcover, 2015 ed.)
Takashi Yamamoto
R4,617 Discovery Miles 46 170 Ships in 10 - 15 working days

This book serves as an introduction to targeted genome editing, beginning with the background of this rapidly developing field and methods for generation of engineered nucleases. Applications of genome editing tools are then described in detail, in iPS cells and diverse organisms such as mice, rats, marine invertebrates, fish, frogs, and plants. Tools that are mentioned include zinc finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs), and CRISPR/Cas9, all of which have received much attention in recent years as breakthrough technologies. Genome editing with engineered nucleases allows us to precisely change the target genome of living cells and is a powerful way to control functional genes. It is feasible in almost all organisms ranging from bacteria to plants and animals, as well as in cultured cells such as ES and iPS cells. Various genome modifications have proven successful, including gene knockout and knock-in experiments with targeting vectors and chromosomal editing. Genome editing technologies hold great promise for the future, for example in biomedical research, clinical medicine, and generation of crops and livestock with desirable traits. A wide range of readers will find this book interesting, and with its focus on applications in a variety of organisms and cells, the book will be valuable for life scientists in all fields.

Molecular Embryology - Methods and Protocols (Hardcover, 2nd ed. 2009): Paul Sharpe, Ivor Mason Molecular Embryology - Methods and Protocols (Hardcover, 2nd ed. 2009)
Paul Sharpe, Ivor Mason
R5,765 Discovery Miles 57 650 Ships in 10 - 15 working days

In Molecular Embryology: Methods and Protocols, Second Edition, expert investigators provide a comprehensive guide to the cutting-edge methods used across the dramatically growing field of vertebrate molecular embryology. Time-tested techniques take advantage of the most commonly used vertebrate experimental models: murine embryos for their genetics, chick embryos for in vivo manipulation, zebrafish for mutagenesis, amphibian embryos, and nonvertebrate chordates. The second edition collects classic protocols which have become standard techniques in the laboratory and presents them in a complementary fashion with novel and emerging approaches, allowing researcher to become more familiar with commonly studied embryos used in biomedical research. Insightful to the experienced professional, Molecular Embryology: Methods and Protocols, Second Edition, presents cutting-edge findings of perhaps the greatest period in growth and productivity in the field of developmental biology.

Reproduction in Mammals - The Female Perspective (Hardcover): Virginia Hayssen, Teri Orr Reproduction in Mammals - The Female Perspective (Hardcover)
Virginia Hayssen, Teri Orr
R2,127 Discovery Miles 21 270 Ships in 10 - 15 working days

Newborn mammals can weigh as little as a dime or as much as a motorcycle. Some receive milk for only a few days, whereas others nurse for years. Humans typically have only one baby at a time following nine months of pregnancy, but other mammals have twenty or more young after only a few weeks in utero. What causes this incredible reproductive diversity? In Reproduction in Mammals, Virginia Hayssen and Teri Orr present readers with a fascinating examination of the varied reproductive strategies of a broad spectrum of mammals, from marsupials to whales. This unique book's comprehensive coverage gathers stories from many taxa into a single, cohesive perspective that centers on the reproductive lives of females. The authors shed light on a number of intriguing questions, including * do bigger moms have bigger babies?* do primates have longer pregnancies than other groups?* does habitat influence animals' reproductive patterns?* do carnivores typically produce larger litters than prey species? The book opens with the authors' definition of what constitutes a female perspective and an examination of the evolution of reproduction in mammals. It then outlines the typical individual mammalian female: her genetics, anatomy, and physiology. Taking a nuanced approach, Hayssen and Orr describe the female reproductive cycle and explore female mammals' interactions with males and offspring. Readers will come away from this thought-provoking book with an understanding not only of how reproduction fits into the lives of female mammals but also of how biology has affected the enormously diverse reproductive patterns of the phenotypes we observe today.

Comparative Vertebrate Reproduction (Hardcover, 1998 ed.): Julian Lombardi Comparative Vertebrate Reproduction (Hardcover, 1998 ed.)
Julian Lombardi
R5,858 Discovery Miles 58 580 Ships in 10 - 15 working days

Comparative Vertebrate Reproduction is the only comprehensive textbook covering major topics in the reproductive biology of vertebrates, from sexuality and gametogenesis to reproductive ecology and life history tactics. The work draws heavily on recent reviews and papers while placing topics in a historical context and conceptual framework. In addition, the author provides detailed comparative surveys of each of the major topics discussed. Comparative Vertebrate Reproduction has been written as a textbook for upper-level undergraduate and graduate-level students in biology, zoology, physiology, animal science, and veterinary medicine. The work also serves as an excellent reference for researchers in medical and veterinary schools working in reproductive medicine.

Molecular Ecology and Conservation Genetics of Neotropical Mammals (Hardcover, 1st ed. 2021): Maximiliano Nardelli, Juan... Molecular Ecology and Conservation Genetics of Neotropical Mammals (Hardcover, 1st ed. 2021)
Maximiliano Nardelli, Juan Ignacio Tunez
R4,650 Discovery Miles 46 500 Ships in 10 - 15 working days

Although all living beings modify their environment, human beings have acquired the ability to do so on a superlative space-time scale. As a result of industrialization and the use of new technologies, the anthropogenic impact has been increasing in the last centuries, causing reductions in the sizes or the extinction of numerous wild populations. In this sense, from the field of conservation genetics, various efforts have been made in recent decades to provide new knowledge that contributes to the conservation of populations, species, and habitats. In this book, we summarize the concrete contributions of researchers to the conservation of the Neotropical mammals using Molecular Ecology techniques. The book is divided into three major sections. The first section provides an up-to-date review of the conservation status of Neotropical mammals, the applications of the molecular markers in its conservation, and the use of non-invasive and forensic genetic techniques. The second and third sections present, respectively, a series of case studies in various species or taxonomic groups of Neotropical mammals.

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