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Books > Science & Mathematics > Biology, life sciences > Zoology & animal sciences > Animal reproduction

Genetics of the Mouse (Paperback, Softcover reprint of the original 1st ed. 2015): Jean Louis Guenet, Fernando Benavides,... Genetics of the Mouse (Paperback, Softcover reprint of the original 1st ed. 2015)
Jean Louis Guenet, Fernando Benavides, Jean-Jacques Panthier, Xavier Montagutelli
R6,263 Discovery Miles 62 630 Ships in 10 - 15 working days

This book, written by experienced geneticists, covers topics ranging from the natural history of the mouse species, its handling and reproduction in the laboratory, and its classical genetics and cytogenetics, to modern issues including the analysis of the transcriptome, the parental imprinting and X-chromosome inactivation. The strategies for creating all sorts of mutations, either by genetic engineering or by using mutagens, are also reviewed and discussed in detail. Finally, a last chapter outlines the methodology used for the analysis of complex or quantitative traits. The authors also discuss the importance of accurate phenotyping, which is now performed in the mouse clinics established worldwide and identify the limits of the mouse model, which under certain circumstances can fail to present the phenotype expected from the cognate condition in the human model. For each chapter an up-to-date list of pertinent references is provided. In short, this book offers an essential resource for all scientists who use or plan to use mice in their research.

Molecular Geometry of Body Pattern in Birds (Paperback, Softcover reprint of the original 1st ed. 2012): Antonio Lima-De-Faria Molecular Geometry of Body Pattern in Birds (Paperback, Softcover reprint of the original 1st ed. 2012)
Antonio Lima-De-Faria
R4,385 Discovery Miles 43 850 Ships in 10 - 15 working days

After having read this book you will never see birds in the same way again. The unexpected patterns displayed by a bird's body have been seen as bizarre events that demanded little attention or were described as 'amazing curiosities'. None of these surprising features seem to be fortuitous. They appear to be an integral part of a rigid order and a coherent geometry, which is directed by simple gene interactions and molecular cascades occurring at various cellular levels, and at different times, during the organism's development. A novel geometry unfolds in front of your eyes, giving the body configurations another meaning. Lima-de-Faria is Professor Emeritus of Molecular Cytogenetics at Lund University, Lund, Sweden. This is his sixth book dealing with the molecular organization of the chromosome and its implications for the understanding of the mechanisms responsible for biological evolution.

Advanced Protocols for Animal Transgenesis - An ISTT Manual (Paperback, Softcover reprint of the original 1st ed. 2011):... Advanced Protocols for Animal Transgenesis - An ISTT Manual (Paperback, Softcover reprint of the original 1st ed. 2011)
Shirley Pease, Thomas L. Saunders
R4,602 Discovery Miles 46 020 Ships in 10 - 15 working days

This laboratory manual, published in cooperation with the International Society for Transgenic Technology (ISTT), provides almost all current methods that can be applied to the creation and analysis of genetically modified animals. The chapters have been contributed by leading scientists who are actively using the technology in their laboratories. Based on their first-hand experience the authors also provide helpful notes and troubleshooting sections. Topics range from standard techniques, such as pronuclear microinjection of DNA, to more sophisticated and modern methods, such as the derivation and establishment of embryonic stem (ES) cell lines, with defined inhibitors in cell culture medium. In addition, related topics with relevance to the field are addressed, including global web-based resources, legal issues, colony management, shipment of mice and embryos, and the three R's: refinement, reduction and replacement.

Muscle Gene Therapy - Methods and Protocols (Paperback, Softcover reprint of the original 1st ed. 2011): Dongsheng Duan Muscle Gene Therapy - Methods and Protocols (Paperback, Softcover reprint of the original 1st ed. 2011)
Dongsheng Duan
R4,189 Discovery Miles 41 890 Ships in 10 - 15 working days

Gene therapy offers many conceptual advantages to treat muscle diseases, especially various forms of muscular dystrophies; however, it faces a number of unique challenges, including the need to deliver a therapeutic vector to all muscles throughout the body. In Muscle Gene Therapy: Methods and Protocols, expert researchers in the field present a collection of techniques aimed at bridging the translational gap in muscle gene therapy between the prevalent rodent models and vitally important larger animal models. Divided into three sections, this volume examines basic protocols for optimizing the muscle gene expression cassette and for evaluating the therapeutic outcomes, new developments in muscle gene therapy technology such as adeno-associated viral vector (AAV), oligonucleotide-mediated exon-skipping, and novel RNA-based strategies, and step-by-step guidance on muscle gene delivery in swine, ovine, canine, and non-human primates. Written in the highly successful Methods in Molecular Biology (TM) series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, detailed, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Muscle Gene Therapy: Methods and Protocols serves as an invaluable resource for graduate students, post-doctoral fellows, and principle investigators pursuing the crucial advancement of muscle disease gene therapy in the hope of someday curing these debilitating disorders.

Managing the Prenatal Environment to Enhance Livestock Productivity (Paperback, 2010 ed.): Paul L. Greenwood, Alan W. Bell,... Managing the Prenatal Environment to Enhance Livestock Productivity (Paperback, 2010 ed.)
Paul L. Greenwood, Alan W. Bell, Philip E. Vercoe, Gerrit J. Viljoen
R4,353 Discovery Miles 43 530 Ships in 10 - 15 working days

Prenatal life is the period of maximal development in animals, and it is well recognised that factors that alter development can have profound effects on the embryonic, fetal and postnatal animal. Scientists involved in research on livestock productivity have for decades studied postnatal consequences of fetal development on productivity. Recently, however, there has been a surge in interest in how to manage prenatal development to enhance livestock health and productivity. This has occurred largely due to the studies that show human health in later life can be influenced by events during prenatal life, and establishment of the Fetal Origins and the Thrifty Phenotype Hypotheses. This book, Managing the Prenatal Environment to Enhance Livestock Productivity reviews phenotypic consequences of prenatal development, and provides details of mechanisms that underpin these effects in ruminants, pigs and poultry. The chapters have been divided into three parts: Quantification of prenatal effects on postnatal productivity, mechanistic bases of postnatal consequences of prenatal development and regulators of fetal and neonatal nutrient supply. Managing the Prenatal Environment to Enhance Livestock Productivity is a reference from which future research to improve the level of understanding and capacity to enhance productivity, health and efficiency of livestock in developing and developed countries will evolve. It is particularly timely given the development of molecular technologies that are providing new insight into regulation and consequences of growth and development of the embryo, fetus and neonate.

Biorational Control of Arthropod Pests - Application and Resistance Management (Paperback, 2009 ed.): Isaac Ishaaya, A. Rami... Biorational Control of Arthropod Pests - Application and Resistance Management (Paperback, 2009 ed.)
Isaac Ishaaya, A. Rami Horowitz
R5,614 Discovery Miles 56 140 Ships in 10 - 15 working days

For nearly 50 years, pest control was mostly based on broad-spectrum conv- tional insecticides such as organochlorines, organophosphates, carbamates and pyrethroids. However, the severe adverse effects of pesticides on the environment, problems of resistance reaching crisis proportions and public protests led to stricter regulations and legislation aimed at reducing their use. Ways to reduce the use of synthetic pesticides in plant protection and to use more alternative and novel me- ods for pest control or biorational control are the challenges of pest control for the twenty-first century. The term biorational (biological + rational) pesticides can be defined as the use of specific and selective chemicals, often with a unique modes of action, that are compatible with natural enemies and the environment, with minimal effect on n- target organisms. Biorational control is based on a diversity of chemical, biological and physical approaches for controlling insect pests which results in minimum risk to man and the environment.

Animal Cell Biotechnology - Methods and Protocols (Paperback, 2nd ed. 2007): Ralf Poertner Animal Cell Biotechnology - Methods and Protocols (Paperback, 2nd ed. 2007)
Ralf Poertner
R4,418 Discovery Miles 44 180 Ships in 10 - 15 working days

The second edition of this book constitutes a comprehensive manual of new techniques for setting up mammalian cell lines for production of biopharmaceuticals, and for optimizing critical parameters for cell culture considering the whole cascade from lab to final production. The chapters are written by world-renowned experts and the volume's five parts reflect the processes required for different stages of production. This book is a compendium of techniques for scientists in both industrial and research laboratories that use mammalian cells for biotechnology purposes.

Gene Therapy Protocols - Volume 1: Production and In Vivo Applications of Gene Transfer Vectors (Paperback, 3rd ed. 2008):... Gene Therapy Protocols - Volume 1: Production and In Vivo Applications of Gene Transfer Vectors (Paperback, 3rd ed. 2008)
Joseph Ledoux
R2,904 Discovery Miles 29 040 Ships in 10 - 15 working days

In this book internationally recognized investigators describe cutting-edge laboratory techniques for the study of Production and In Vivo Applications of Gene Transfer Vectors and Design and Characterization of Gene Transfer Vectors. Readers will find a comprehensive resource of current and emerging methods for the production of viral and non-viral gene transfer vectors, as well as detailed protocols for applications in stem cell biology, cancer research and infectious disease.

Neural Crest Induction and Differentiation (Paperback, 2006 ed.): Jean-Pierre Saint-Jeannet Neural Crest Induction and Differentiation (Paperback, 2006 ed.)
Jean-Pierre Saint-Jeannet
R4,340 Discovery Miles 43 400 Ships in 10 - 15 working days

Written by an international panel of recognized leaders in the field, Neural Crest Induction and Differentiation discusses all aspects of modern neural crest biology from its evolutionary significance to its specification, migration, plasticity and contribution to multiple lineages of the vertebrate body, to the pathologies associated with abnormal neural crest development and function. Abundant color figures enhance the text providing clear and attractive illustrations of central issues and concepts.

Evolutionary Biology: Mechanisms and Trends (Paperback, 2012 ed.): Pierre Pontarotti Evolutionary Biology: Mechanisms and Trends (Paperback, 2012 ed.)
Pierre Pontarotti
R4,372 Discovery Miles 43 720 Ships in 10 - 15 working days

The annual Evolutionary Biology Meetings in Marseilles serve to gather leading evolutionary biologists and other scientists using evolutionary biology concepts, e.g. for medical research. The aims of these meetings are to promote the exchange of ideas and to encourage interdisciplinary collaborations. This book collects 19 selected contributions presented at the 15th meeting, which took place in September 2011. It starts with a description of the life and work of J.B.S. Haldane, a remarkable evolutionary biologist of the 20th century. The remaining chapters are grouped under the following three themes: * New Concepts in Evolutionary Biology * Macroevolution: Mechanisms and Trends * Genome Evolution Offering an up-to-date overview of recent results in the field of evolutionary biology, this book is an invaluable source of information for scientists, teachers and advanced students.

Evolutionary Biology - Concepts, Molecular and Morphological Evolution (Paperback, 2010 ed.): Pierre Pontarotti Evolutionary Biology - Concepts, Molecular and Morphological Evolution (Paperback, 2010 ed.)
Pierre Pontarotti
R6,340 Discovery Miles 63 400 Ships in 10 - 15 working days

The annual Evolutionary Biology Meetings in Marseille aim to bring together leading scientists, promoting an exchange of state-of-the-art knowledge and the formation of inter-group collaborations. This book presents the most representative contributions to the 13th meeting, which was held in September 2009. It comprises 21 chapters, which are organized into the following three categories: * Evolutionary Biology Concepts * Genome/Molecular Evolution * Morphological Evolution/Speciation This book offers an up-to-date overview of evolutionary biology concepts and their use in the biology of the 21st century.

Primates, Pathogens, and Evolution (Paperback, Softcover reprint of the original 1st ed. 2013): Jessica F. Brinkworth, Kate... Primates, Pathogens, and Evolution (Paperback, Softcover reprint of the original 1st ed. 2013)
Jessica F. Brinkworth, Kate Pechenkina
R5,559 Discovery Miles 55 590 Ships in 10 - 15 working days

The immune systems of human and non-human primates have diverged over time, such that some species differ considerably in their susceptibility, symptoms, and survival of particular infectious diseases. Variation in primate immunity is such that major human pathogens - such as immunodeficiency viruses, herpesviruses and malaria-inducing species of Plasmodium - elicit striking differences in immune response between closely related species and within primate populations. These differences in immunity are the outcome of complex evolutionary processes that include interactions between the host, its pathogens and symbiont/commensal organisms. The success of some pathogens in establishing persistent infections in humans and other primates has been determined not just by the molecular evolution of the pathogen and its interactions with the host, but also by the evolution of primate behavior and ecology, microflora, immune factors and the evolution of other biological systems. To explore how interactions between primates and their pathogens have shaped their mutual molecular evolution, Primates, Pathogens and Evolution brings together research that explores comparative primate immune function, the emergence of major and neglected primate diseases, primate-microorganism molecular interactions, and related topics. This book will be of interest to anyone curious as to why infectious diseases manifest differently in humans and their closest relatives. It will be of particular interest to scholars specializing in human and non-human primate evolution, epidemiology and immunology, and disease ecology. Primates, Pathogens and Evolution offers an overview and discussion of current findings on differences in the molecular mechanics of primate immune response, as well as on pathogen-mediated primate evolution and human and non-human primate health.

Evolutionary Biology: Exobiology and Evolutionary Mechanisms (Paperback, Softcover reprint of the original 1st ed. 2013):... Evolutionary Biology: Exobiology and Evolutionary Mechanisms (Paperback, Softcover reprint of the original 1st ed. 2013)
Pierre Pontarotti
R5,192 Discovery Miles 51 920 Ships in 10 - 15 working days

This book presents 19 selected contributions to the 16th Evolutionary Biology Meeting, which took place in September 2012 in Marseilles. The aims of these annual meetings, which gather together leading evolutionary biologists and other scientists, are to promote the exchange of ideas and to encourage interdisciplinary collaborations. The first chapter deals with the history of a great discovery: The first experiments on ascidian and sea urchin egg fertilization. The remaining contributions are grouped under the following categories: * Evolutionary biology concepts * Exobiology and the origin of life * Evolutionary mechanisms Offering an up-to-date overview of recent findings in the field of evolutionary biology, this book is an invaluable source of information for scientists, teachers and advanced students.

Swimming Physiology of Fish - Towards Using Exercise to Farm a Fit Fish in Sustainable Aquaculture (Paperback): Arjan P.... Swimming Physiology of Fish - Towards Using Exercise to Farm a Fit Fish in Sustainable Aquaculture (Paperback)
Arjan P. Palstra, Josep V. Planas
R5,559 Discovery Miles 55 590 Ships in 10 - 15 working days

In light of mounting fishing pressures, increased aquaculture production and a growing concern for fish well-being, improved knowledge on the swimming physiology of fish and its application to fisheries science and aquaculture is needed. This book presents recent investigations into some of the most extreme examples of swimming migrations in salmons, eels and tunas, integrating knowledge on their performance in the laboratory with that in their natural environment. For the first time, the application of swimming in aquaculture is explored by assessing the potential impacts and beneficial effects. The modified nutritional requirements of "athletic" fish are reviewed as well as the effects of exercise on muscle composition and meat quality using state-of-the-art techniques in genomics and proteomics. The last chapters introduce zebrafish as a novel exercise model and present the latest technologies for studying fish swimming and aquaculture applications.

Mouse Models of Human Blood Cancers - Basic Research and Pre-clinical Applications (Paperback, 2008 ed.): Shaoguang Li Mouse Models of Human Blood Cancers - Basic Research and Pre-clinical Applications (Paperback, 2008 ed.)
Shaoguang Li
R4,356 Discovery Miles 43 560 Ships in 10 - 15 working days

In this book, Dr. Li and his author team plan to emphasize why mouse models are useful in vivo systems for understanding disease mechanisms and developing therapeutic strategies in blood cancers. The authors do not intend to cover all types of blood cancers; instead, they will focus on some major ones such as leukemias and lymphomas. However, the authors will try to cover as much as they can the cancer types and point out that many blood cancers need to be studied in mouse disease models although they are still not available at present. A major focus in the book will be to show what we can or cannot learn from mouse disease models and to also show the critical contributions of mouse models in therapeutic drug development.

Building Babies - Primate Development in Proximate and Ultimate Perspective (Paperback, 2013 ed.): Kathryn B. H. Clancy, Katie... Building Babies - Primate Development in Proximate and Ultimate Perspective (Paperback, 2013 ed.)
Kathryn B. H. Clancy, Katie Hinde, Julienne N. Rutherford
R4,422 Discovery Miles 44 220 Ships in 10 - 15 working days

The ontogeny of each individual contributes to the physical, physiological, cognitive, neurobiological, and behavioral capacity to manage the complex social relationships and diverse foraging tasks that characterize the primate order. For these reasons Building Babies explores the dynamic multigenerational processes of primate development. The book is organized thematically along the developmental trajectory:conception, pregnancy, lactation, the mother-infant dyad, broader social relationships, and transitions to independence. In this volume, the authors showcase the myriad approaches to understanding primate developmental trajectories from both proximate and ultimate perspectives. These collected chapters provide insights from experimental manipulations in captive settings to long-term observations of wild-living populations and consider levels of analysis from molecule to organism to social group to taxon. Strepsirrhines, New World monkeys, Old World monkeys, apes, and humans are all well-represented. Contributions by anthropologists, microbiologists, psychologists, population geneticists, and other primate experts provide Building Babies a uniquely diverse voice. Building Babies features multi- and trans-disciplinary research approaches to primate developmental trajectories and is particularly useful for researchers and instructors in anthropology, animal behavior, psychology, and evolutionary biology. This book also serves as a supplement to upper-level undergraduate courses or graduate seminars on primate life history and development. In these contexts, the book provides exposure to a wide range of methodological and theoretical perspectives on developmental trajectories and models how researchers might productively integrate such approaches into their own work.

Bemisia: Bionomics and Management of a Global Pest (Paperback, 2010 ed.): Philip A. Stansly, Steven E. Naranjo Bemisia: Bionomics and Management of a Global Pest (Paperback, 2010 ed.)
Philip A. Stansly, Steven E. Naranjo
R5,655 Discovery Miles 56 550 Ships in 10 - 15 working days

Bemisia tabaci (Gennedius) has distinguished itself from the more than 1,000 whitefly species in the world by its adaptability, persistence and potential to damage a wide range of agricultural and horticultural crops in all six of the world's inhabited continents. B. tabaci inflicts plant damage through direct feeding, inducement of plant disorders, vectoring of plant viruses and excretion of honeydew. This book collates multiple aspects of the pest ranging from basic to applied science and molecular to landscape levels of investigation. Experts in multiple disciplines provide broad, but detailed summaries and discussion of taxonomy, genetics, anatomy, morphology, physiology, behavior, ecology, symbiotic relationships, virus vector associations and various tactics for integrated management of this pest insect. The book is focused primarily on progress during the last 10-15 years and is directed at workers in the field as well as the informed professional who may not necessarily specialize in whitefly research. The book is unique in providing broad coverage in relatively few chapters by recognized experts that highlight the state-of-the-art in our understanding of this fascinating but troublesome cosmopolitan pest.

Marsupial Genetics and Genomics (Paperback, 2010 ed.): Paul D. Waters, Janine E. Deakin, Jennifer A.Marshall Graves Marsupial Genetics and Genomics (Paperback, 2010 ed.)
Paul D. Waters, Janine E. Deakin, Jennifer A.Marshall Graves
R5,649 Discovery Miles 56 490 Ships in 10 - 15 working days

Marsupials belong to the Class Mammalia, sharing some features with other mammals, yet they also possess many unique features. It is their differences from the more traditionally studied mammals, such as mice and humans, that is of greatest value to comparative studies. Sequencing of genomes from two distantly related marsupials, the short grey-tailed opossum from South America and the Australian tammar wallaby, has launched marsupials into the genomics era and accelerated the rate of progress in marsupial research. With the current worldwide concern for the plight of the endangered Tasmanian devil, marsupial genetics and genomics research is even more important than ever if this species is to be saved from extinction. This volume recounts some of the history of research in this field and highlights the most recent advances in the many different areas of marsupial genetics and genomics research.

Reproductive Technologies in Farm Animals (Paperback, 2nd edition): Ian Gordon Reproductive Technologies in Farm Animals (Paperback, 2nd edition)
Ian Gordon
R1,516 R1,427 Discovery Miles 14 270 Save R89 (6%) Ships in 9 - 17 working days

Building on the successful structure of the first edition, the second edition of Reproductive Technologies in Farm Animals has been totally updated and revised to provide an up to date account of the key techniques employed in manipulating reproduction in farm animals, including beef and dairy cattle, pigs, sheep, goats, buffaloes, camelids, horses and poultry. A classic introductory text to the subject, the book is based on a comprehensive review of the current literature. It: - outlines different agricultural systems and explores the ethical implications of modern farming methods; - details the many new developments, including the commercial application of sexed semen and large-scale application of in vitro produced cattle embryos; - provides a valuable synopsis of current and future reproductive technologies, such as cloning and the production of transgenic animals. This text remains key reading for students in animal science, agriculture, veterinary medicine and biology, and veterinary practitioners and farmers who wish to keep updated on developments in techniques that may be useful in their daily practice.

Boar Reproduction - Fundamentals and New Biotechnological Trends (Paperback, 2013 ed.): Sergi Bonet, Isabel Casas, William V.... Boar Reproduction - Fundamentals and New Biotechnological Trends (Paperback, 2013 ed.)
Sergi Bonet, Isabel Casas, William V. Holt, Marc Yeste
R7,221 Discovery Miles 72 210 Ships in 10 - 15 working days

Latent knowledge in the field of pig reproduction is vast but scattered, making it difficult to take in all information at a glance. Moreover, nascent branches in biotechnology cannot grow if deprived of roots. The book Boar Reproduction: Fundamentals and New Biotechnological Trends links the past, the present and the emerging scientific research fields on reproductive biotechnology, offering a rigorous but easy to follow compilation of topics, from "old favorites" to the latest advances. The book is organized in three parts. The chapters of the first and second part cover various biological aspects of boar spermatozoa within the male, and within the female environments, respectively. The most common laboratory and artificial insemination techniques are discussed in the third part. As an additional feature, some chapters focus on the basis of a technology transfer to bring research expertise from basic science to the market, making the information provided in this book suitable for academic, research and other professional applications.

Mutagenesis of the Mouse Genome (Paperback, Softcover reprint of the original 1st ed. 2004): Monica Justice, Mary Bedell Mutagenesis of the Mouse Genome (Paperback, Softcover reprint of the original 1st ed. 2004)
Monica Justice, Mary Bedell
R2,838 Discovery Miles 28 380 Ships in 10 - 15 working days

The Second Georgia Genetics Symposium was held color. Soon after, he joined the sta? of The Jackson in September 2000, and the development of this Laboratory in Bar Harbor, Maine. book took place over the nearly 4 years that ensued. Much of Bill's research at the lab was centered During this time, many advances in the Genome around investigating phenotypic variability within Project and mouse mutagenesis were made. In the highly inbred strains, and in that connection he book overview, we discuss the development of the developed the technique of ovarian transplanta- Genome Project (which is the context for the sym- tion (even using embryonic donors) and a genetic posium), the role the mouse was playing at that scheme whereby graft compatibility could be time, how that role has evolved, and how the combined with the ability to distinguish o?spring chapters of the book address issues in mouse func- from donor and regenerated host ovaries. His tional genetics. Many of the chapters in this book work was in?uenced by the second World War, will provide useful resources for years to come. ?rst because The Jackson Laboratory turned into Of greater impact, our keynote speaker, the a production colony for the military, primarily to mutagenesis pioneer William L. (Bill) Russell, produce mice for typhoid testing, and secondly, passed away on July 23, 2003.

Chromosome Atlas: Fish, Amphibians, Reptiles and Birds - Volume 3 (Paperback, 1975 ed.): Kurt Benirschke, Tao C Hsu, M. L.... Chromosome Atlas: Fish, Amphibians, Reptiles and Birds - Volume 3 (Paperback, 1975 ed.)
Kurt Benirschke, Tao C Hsu, M. L. Becak, W Becak, F L Roberts, …
R3,398 Discovery Miles 33 980 Ships in 10 - 15 working days
Bones, Genetics, and Behavior of Rhesus Macaques - Macaca Mulatta of Cayo Santiago and Beyond (Paperback, 2012 ed.): Qian Wang Bones, Genetics, and Behavior of Rhesus Macaques - Macaca Mulatta of Cayo Santiago and Beyond (Paperback, 2012 ed.)
Qian Wang
R4,359 Discovery Miles 43 590 Ships in 10 - 15 working days

Foreword by Phillip V. Tobias The introduction of rhesus macaques to Cayo Santiago, Puerto Rico in 1938, and the subsequent development of the CPRC for biomedical research, continues its long history of stimulating studies in physical anthropology. The CPRC monkey colonies, and the precise demographic data on the derived skeletal collection in the Center's Laboratory of Primate Morphology and Genetics (LPMG), provide rare opportunities for morphological, developmental, functional, genetic, and behavioral studies across the life span of rhesus macaques as a species, and as a primate model for humans. The book grows out of a symposium Wang is organizing for the 78th annual meeting of the American Association of Physical Anthropologists to be held in April 2009. This symposium will highlight recent and ongoing research in, or related to, physical anthropology, and reveal the numerous research opportunities that still exist at this unusual rhesus facility. Following an initial historical review of CPRC and its research activities, this book will emphasize recent and current researches on growth, function, genetics, pathology, aging, and behavior, and the impact of these researches on our understanding of rhesus and human morphology, development, genetics, and behavior. Fourteen researchers will present recent and current studies on morphology, genetics, and behavior, with relevance to primate and human growth, health, and evolution. The book will include not only papers presented in the symposium, but also papers from individuals who could not present their work at the meeting due to limitations in the maximum number (14) of permitted speakers.

Mouse as a Model Organism - From Animals to Cells (Paperback, 2011 ed.): Cord Brakebusch, Taina Pihlajaniemi Mouse as a Model Organism - From Animals to Cells (Paperback, 2011 ed.)
Cord Brakebusch, Taina Pihlajaniemi
R4,315 Discovery Miles 43 150 Ships in 10 - 15 working days

Cell culture based research is important for our understanding of biological processes at the cellular and molecular level. Using this approach, the previous decades have produced a wealth of mechanistic information in all areas of biomedical research. Such in vitro research, however, lacks the complexity of in vivo investigations, where many different cell types interact with each other in a normal, three-dimensional environment, with normal levels of cytokines and growth factors. Furthermore, complex human diseases, such as cancer, diabetes or chronic inflammation, can only be modeled in vivo. Due to its small size, its short reproduction time, and the possibility to introduce specific gene mutations, the mouse has become the favourite mammalian model organism to study in vivo function of genes during development and in disease. This book combines review articles on selected subjects presented at the symposium "Mouse as a Model Organism - From Animals to Cells", held in Rovaniemi, Finland, 2009. Among other topics, high-throughput phenotyping of mouse mutants, mouse phenotypes dependent on nature and nuture, and a spectrum of in vivo, ex vivo and in vitro methods to study cancer in mice are described. This book will give an excellent introduction to scientists interested in the use of mice as a model to understand complex biological questions in the post-genomic era. It will highlight the possibilities, but also discuss the current problems and shortcomings, to give a realistic view of the current state-of-art in this fascinating field of biomedical research.

Comparative Genomics (Paperback, 2013 ed.): Xuhua Xia Comparative Genomics (Paperback, 2013 ed.)
Xuhua Xia
R1,699 Discovery Miles 16 990 Ships in 10 - 15 working days

This book provides an evolutionary conceptual framework for comparative genomics, with the ultimate objective of understanding the loss and gain of genes during evolution, the interactions among gene products, and the relationship between genotype, phenotype and the environment. The many examples in the book have been carefully chosen from primary research literature based on two criteria: their biological insight and their pedagogical merit. The phylogeny-based comparative methods, involving both continuous and discrete variables, often represent a stumbling block for many students entering the field of comparative genomics. They are numerically illustrated and explained in great detail. The book is intended for researchers new to the field, i.e., advanced undergraduate students, postgraduates and postdoctoral fellows, although professional researchers who are not in the area of comparative genomics will also find the book informative.

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