Genetics of the Mouse (Paperback, Softcover reprint of the original 1st ed. 2015)

This book, written by experienced geneticists, covers topics ranging from the natural history of the mouse species, its handling and reproduction in the laboratory, and its classical genetics and cytogenetics, to modern issues including the analysis of the transcriptome, the parental imprinting and X-chromosome inactivation. The strategies for creating all sorts of mutations, either by genetic engineering or by using mutagens, are also reviewed and discussed in detail. Finally, a last chapter outlines the methodology used for the analysis of complex or quantitative traits. The authors also discuss the importance of accurate phenotyping, which is now performed in the mouse clinics established worldwide and identify the limits of the mouse model, which under certain circumstances can fail to present the phenotype expected from the cognate condition in the human model. For each chapter an up-to-date list of pertinent references is provided. In short, this book offers an essential resource for all scientists who use or plan to use mice in their research.

General

Imprint:	Springer-Verlag
Country of origin:	Germany
Release date:	September 2016
First published:	2015
Authors:	Jean Louis Guenet • Fernando Benavides • Jean-Jacques Panthier • Xavier Montagutelli
Dimensions:	235 x 155 x 22mm (L x W x T)
Format:	Paperback
Pages:	408
Edition:	Softcover reprint of the original 1st ed. 2015
ISBN-13:	978-3-662-51016-2
Categories:	Books > Medicine > Pre-clinical medicine: basic sciences > Medical genetics Books > Science & Mathematics > Biology, life sciences > Zoology & animal sciences > Animal reproduction Books > Science & Mathematics > Biology, life sciences > Zoology & animal sciences > Animal pathology & diseases Books > Professional & Technical > Biochemical engineering > Biotechnology > Genetic engineering Books > Science & Mathematics > Biology, life sciences > Life sciences: general issues > Genetics (non-medical) > General
LSN:	3-662-51016-2
Barcode:	9783662510162

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