The concise yet authoritative presentation of key techniques for basic mixtures experiments Inspired by the author's bestselling advanced book on the topic, A Primer on Experiments with Mixtures provides an introductory presentation of the key principles behind experimenting with mixtures. Outlining useful techniques through an applied approach with examples from real research situations, the book supplies a comprehensive discussion of how to design and set up basic mixture experiments, then analyze the data and draw inferences from results. Drawing from his extensive experience teaching the topic at various levels, the author presents the mixture experiments in an easy-to-follow manner that is void of unnecessary formulas and theory. Succinct presentations explore key methods and techniques for carrying out basic mixture experiments, including: * Designs and models for exploring the entire simplex factor space, with coverage of simplex-lattice and simplex-centroid designs, canonical polynomials, the plotting of individual residuals, and axial designs * Multiple constraints on the component proportions in the form of lower and/or upper bounds, introducing L-Pseudocomponents, multicomponent constraints, and multiple lattice designs for major and minor component classifications * Techniques for analyzing mixture data such as model reduction and screening components, as well as additional topics such as measuring the leverage of certain design points * Models containing ratios of the components, Cox's mixture polynomials, and the fitting of a slack variable model * A review of least squares and the analysis of variance for fitting data Each chapter concludes with a summary and appendices with details on the technical aspects of the material. Throughout the book, exercise sets with selected answers allow readers to test their comprehension of the material, and References and Recommended Reading sections outline further resources for study of the presented topics. A Primer on Experiments with Mixtures is an excellent book for one-semester courses on mixture designs and can also serve as a supplement for design of experiments courses at the upper-undergraduate and graduate levels. It is also a suitable reference for practitioners and researchers who have an interest in experiments with mixtures and would like to learn more about the related mixture designs and models.

The book shows a very original organization addressing in a non traditional way, but with a systematic approach, to who has an interest in using mathematics in the social sciences.

The book is divided in four parts: (a) a historical part, written by Vittorio Capecchi which helps us understand the changes in the relationship between mathematics and sociology by analyzing the mathematical models of Paul F. Lazarsfeld, the model of simulation and artificial societies, models of artificial neural network and considering all the changes in scientific paradigms considered; (b) a part coordinated by Pier Luigi Contucci on mathematical models that consider the relationship between the mathematical models that come from physics and linguistics to arrive at the study of society and those which are born within sociology and economics; (c) a part coordinated by Massimo Buscema analyzing models of artificial neural networks; (d) a part coordinated by Bruno D'Amore which considers the relationship between mathematics and art.

The title of the book "Mathematics and Society" was chosen because the mathematical applications exposed in the book allow you to address two major issues: (a) the general theme of technological innovation and quality of life (among the essays are on display mathematical applications to the problems of combating pollution and crime, applications to mathematical problems of immigration, mathematical applications to the problems of medical diagnosis, etc.) (b) the general theme of technical innovation and creativity, for example the art and mathematics section which connects to the theme of creative cities.

The book is very original because it is not addressed only to those who are passionate about mathematical applications in social science but also to those who, in different societies, are: (a) involved in technological innovation to improve the quality of life; (b) involved in the wider distribution of technological innovation in different areas of creativity (as in the project "Creative Cities Network" of UNESCO).

This book contains a collection of original research articles and review articles that describe novel mathematical modeling techniques and the application of those techniques to models of cell motility in a variety of contexts. The aim is to highlight some of the recent mathematical work geared at understanding the coordination of intracellular processes involved in the movement of cells. This collection will benefit researchers interested in cell motility as well graduate students taking a topics course in this area.

This book develops methods using mathematical kinetic theory to describe the evolution of several socio-biological systems. Specifically, the authors deal with modeling and simulations of biological systems constituted by large populations of interacting cells, whose dynamics follow the rules of mechanics as well as their own ability to organize movement and biological functions. It proposes a new biological model focused on the analysis of competition between cells of an aggressive host and cells of the immune system. Modeling in kinetic theory may represent a way to understand phenomena of non equilibrium statistical mechanics that is not described by the traditional macroscopic approach. The authors of this work focus on models that refer to the Boltzmann equation (generalized Boltzmann models) with the dynamics of populations of several interacting individuals (kinetic population models). The book follows the classical research line applied to modeling real systems, linking the phenomenological observation of systems to modeling and simulations. used to identify the prediction ability of specific models. The book will be a valuable resource for applied mathematicians as well as researchers in the field of biological sciences. It may also be used for advanced graduate courses in biological systems modeling with applications to collective social behavior, immunology, and epidemiology.

This monograph presents a novel method of sliding mode control for switch-regulated nonlinear systems. The Delta Sigma modulation approach allows one to implement a continuous control scheme using one or multiple, independent switches, thus effectively merging the available linear and nonlinear controller design techniques with sliding mode control. Sliding Mode Control: The Delta-Sigma Modulation Approach, combines rigorous mathematical derivation of the unique features of Sliding Mode Control and Delta-Sigma modulation with numerous illustrative examples from diverse areas of engineering. In addition, engineering case studies demonstrate the applicability of the technique and the ease with which one can implement the exposed results. This book will appeal to researchers in control engineering and can be used as graduate-level textbook for a first course on sliding mode control.

Chemical processes in many fields of science and technology, including combustion, atmospheric chemistry, environmental modelling, process engineering, and systems biology, can be described by detailed reaction mechanisms consisting of numerous reaction steps. This book describes methods for the analysis of reaction mechanisms that are applicable in all these fields. Topics addressed include: how sensitivity and uncertainty analyses allow the calculation of the overall uncertainty of simulation results and the identification of the most important input parameters, the ways in which mechanisms can be reduced without losing important kinetic and dynamic detail, and the application of reduced models for more accurate engineering optimizations. This monograph is invaluable for researchers and engineers dealing with detailed reaction mechanisms, but is also useful for graduate students of related courses in chemistry, mechanical engineering, energy and environmental science and biology.

Calculus has been used in solving many scientific and engineering problems. For optimization problems, however, the differential calculus technique sometimes has a drawback when the objective function is step-wise, discontinuous, or multi-modal, or when decision variables are discrete rather than continuous. Thus, researchers have recently turned their interests into metaheuristic algorithms that have been inspired by natural phenomena such as evolution, animal behavior, or metallic annealing.

This book especially focuses on a music-inspired metaheuristic algorithm, harmony search. Interestingly, there exists an analogy between music and optimization: each musical instrument corresponds to each decision variable; musical note corresponds to variable value; and harmony corresponds to solution vector. Just like musicians in Jazz improvisation play notes randomly or based on experiences in order to find fantastic harmony, variables in the harmony search algorithm have random values or previously-memorized good values in order to find optimal solution.

Advanced materials play a crucial role in modern engineering applications where they are often exposed to complex loading and environmental conditions. In many cases, new approaches are needed to characterise these materials and to model their behaviour. Such approaches should be calibrated and validated by specific experimental techniques, quantifying both microstructural features and respective mechanisms at various length scales. The book provides an overview of modern modelling tools and experimental methods that can be employed to analyse and estimate properties and performance of advanced materials. A special feature of the book is the analysis of case studies used to demonstrate the strategies of solving the real-life problems, in which the microstructure of materials directly affects their response to loading and/or environmental conditions. The reader will benefit from a detailed analysis of various methods as well as their implementation for dealing with various advanced materials.

Gabrio Piola works had an enormous impact on the development of applied mathematics and continuum mechanics. An excellent scientific committee who took it upon themselves to translate his complete works. In a second step, they commentedPiola s work and compared it to modern theories in mechanics in order to stress Piola s impact on modern science and proofs that he has set milestones in applied mathematics.
This book presents Piola's original Italian text together with ist translations and their comments. It shows impressively that Gabrio Piola s work must still be regarded as a modern theory."

This book uncovers mathematical structures underlying natural intelligence and applies category theory as a modeling language for understanding human cognition, giving readers new insights into the nature of human thought. In this context, the book explores various topics and questions, such as the human representation of the number system, why our counting ability is different from that which is evident among non-human organisms, and why the idea of zero is so difficult to grasp. The book is organized into three parts: the first introduces the general reason for studying general structures underlying the human mind; the second part introduces category theory as a modeling language and use it for exposing the deep and fascinating structures underlying human cognition; and the third applies the general principles and ideas of the first two parts to reaching a better understanding of challenging aspects of the human mind such as our understanding of the number system, the metaphorical nature of our thinking and the logic of our unconscious dynamics.

This book deals with dynamics of pre-stressed or pre-strained bi-material elastic systems consisting of stack of pre-stressed layers, stack of pre-stressed layers and pre-stressed half space (or half plane), stack of pre-stressed layers as well as absolute rigid foundation, pre-stressed compound solid and hollow cylinders and pre-stressed sandwich hollow cylinders. The problems considered in the book relate to the dynamics of a moving and oscillating moving load, forced vibration caused by linearly located or point located time-harmonic forces acting to the foregoing systems. Moreover, a considerable part of the book relate to the problems regarding the near surface, torsional and axisymmetric longitudinal waves propagation and dispersion in the noted above bi-material elastic systems. The book carries out the investigations within the framework of the piecewise homogeneous body model with the use of the Three-Dimensional Linearized Theory of Elastic Waves in Initially Stressed Bodies.

The domain of inverse problems has experienced a rapid expansion, driven by the increase in computing power and the progress in numerical modeling. When I started working on this domain years ago, I became somehow fr- tratedtoseethatmyfriendsworkingonmodelingwhereproducingexistence, uniqueness, and stability results for the solution of their equations, but that I was most of the time limited, because of the nonlinearity of the problem, to provethatmyleastsquaresobjectivefunctionwasdi?erentiable....Butwith my experience growing, I became convinced that, after the inverse problem has been properly trimmed, the ?nal least squares problem, the one solved on the computer, should be Quadratically (Q)-wellposed, thatis, both we- posed and optimizable: optimizability ensures that a global minimizer of the least squares function can actually be found using e?cient local optimization algorithms, and wellposedness that this minimizer is stable with respect to perturbation of the data. But the vast majority of inverse problems are nonlinear, and the clas- cal mathematical tools available for their analysis fail to bring answers to these crucial questions: for example, compactness will ensure existence, but provides no uniqueness results, and brings no information on the presence or absenceofparasiticlocalminimaorstationarypoints..

This book presents a comprehensive treatise on Riemannian geometric computations and related statistical inferences in several computer vision problems. This edited volume includes chapter contributions from leading figures in the field of computer vision who are applying Riemannian geometric approaches in problems such as face recognition, activity recognition, object detection, biomedical image analysis, and structure-from-motion. Some of the mathematical entities that necessitate a geometric analysis include rotation matrices (e.g. in modeling camera motion), stick figures (e.g. for activity recognition), subspace comparisons (e.g. in face recognition), symmetric positive-definite matrices (e.g. in diffusion tensor imaging), and function-spaces (e.g. in studying shapes of closed contours).

This book presents as its main subject new models in mathematical neuroscience. A wide range of neural networks models with discontinuities are discussed, including impulsive differential equations, differential equations with piecewise constant arguments, and models of mixed type. These models involve discontinuities, which are natural because huge velocities and short distances are usually observed in devices modeling the networks. A discussion of the models, appropriate for the proposed applications, is also provided.

Discontinuous dynamical systems have played an important role in both theory and applications during the last several decades. This is still an area of active research and techniques to make the applications more effective are an ongoing topic of interest. Principles of Discontinuous Dynamical Systems is devoted to the theory of differential equations with variable moments of impulses. It introduces a new strategy of implementing an equivalence to systems whose solutions have prescribed moments of impulses and utilizing special topologies in spaces of piecewise continuous functions. The achievements obtained on the basis of this approach are described in this book. The text progresses systematically, by covering preliminaries in the first four chapters. This is followed by more complex material and special topics such as Hopf bifurcation, Devaney's chaos, and the shadowing property are discussed in the last two chapters. This book is suitable for researchers and graduate students in mathematics and also in diverse areas such as biology, computer science, and engineering who deal with real world problems.

Intelligent paradigms are increasingly finding their ways in the design and development of decision support systems. This book presents a sample of recent research results from key researchers. The contributions include: Introduction to intelligent systems in decision making - A new method of ranking intuitionistic fuzzy alternatives - Fuzzy rule base model identification by bacterial memetic algorithms - Discovering associations with uncertainty from large databases - Dempster-Shafer structures, monotonic set measures and decision making - Interpretable decision-making models - A general methodology for managerial decision making - Supporting decision making via verbalization of data analysis results using linguistic data summaries - Computational intelligence in medical decisions making.

This book is directed to the researchers, graduate students, professors, decision makers and to those who are interested to investigate intelligent paradigms in decision making.

DNA replication is arguably the most crucial process at work in living cells. It is the mechanism by which organisms pass their genetic information from one generation to the next and life on Earth would be unthinkable without it. Despite the discovery of DNA structure in the 1950s, the mechanism of its replication remains rather elusive. This work makes important contributions to this line of research. In particular, it addresses two key questions in the area of DNA replication: which evolutionary forces drive the positioning of replication origins in the chromosome and how is the spatial organization of replication factories achieved inside the nucleus of a cell?. A cross-disciplinary approach uniting physics and biology is at the heart of this research. Along with experimental support, statistical physics theory produces optimal origin positions and provides a model for replication fork assembly in yeast. Advances made here can potentially further our understanding of disease mechanisms such as the abnormal replication in cancer.

These lecture notes are dedicated to the most recent theoretical applications of Black Hole solutions in high-energy physics. The main motivation of this volume is to present the latest black hole backgrounds that are relevant for gauge/gravity correspondence. Leading scientists in the field explain effective techniques for finding singular and cosmological solutions embedded in gauged supergravity, shedding light on underlying properties and symmetries. Starting from a basic level, the mathematical structures underlying black holes and cosmologies are revealed, helping the reader grasp the connection between theoretical approaches and physical observations with insights into possible future developments from both a theoretical and experimental point of view. The topics covered in this volume are based on lectures delivered during the "Theoretical Frontiers in Black Holes and Cosmology" school, held in Natal in June 2015.

This publication showcases the work of UK mathematicians and statisticians by describing industrial problems that have been successfully solved, together with a summary of the financial and/or societal impact that arose from the work. The articles are grouped by sector, and include contributions to climate modelling, engineering and health. The articles are based on Impact Case Studies that were submitted to the Research Excellence Framework (REF2014), a UK government sponsored exercise that assessed the research quality within UK universities. There are many publications in the realm of 'popular mathematics' as well as a vast research literature that underpins this. This work is aimed at a middle ground between these two. Articles contain some mathematical detail, but the emphasis is on telling the story of a successful collaboration between academia and industry and on the results obtained. UK Success Stories in Industrial Mathematics is therefore accessible to a wide readership with interest in the applications of mathematics and statistics to problems of industrial importance and to those interested in how mathematics and statistics research affects our everyday lives and leads to economic and societal benefits.

This contributed volume presents computational models of diabetes that quantify the dynamic interrelationships among key physiological variables implicated in the underlying physiology under a variety of metabolic and behavioral conditions. These variables comprise for example blood glucose concentration and various hormones such as insulin, glucagon, epinephrine, norepinephrine as well as cortisol. The presented models provide a powerful diagnostic tool but may also enable treatment via long-term glucose regulation in diabetics through closed-look model-reference control using frequent insulin infusions, which are administered by implanted programmable micro-pumps. This research volume aims at presenting state-of-the-art research on this subject and demonstrating the potential applications of modeling to the diagnosis and treatment of diabetes. The target audience primarily comprises research and experts in the field but the book may also be beneficial for graduate students.

Analyzing observed or measured data is an important step in applied sciences. The recent increase in computer capacity has resulted in a revolution both in data collection and data analysis. An increasing number of scientists, researchers and students are venturing into statistical data analysis; hence the need for more guidance in this field, which was previously dominated mainly by statisticians.

This handbook fills the gap in the range of textbooks on data analysis. Written in a dictionary format, it will serve as a comprehensive reference book in a rapidly growing field. However, this book is more structured than an ordinary dictionary, where each entry is a separate, self-contained entity. The authors provide not only definitions and short descriptions, but also offer an overview of the different topics. Therefore, the handbook can also be used as a companion to textbooks for undergraduate or graduate courses.

1700 entries are given in alphabetical order grouped into 20 topics and each topic is organized in a hierarchical fashion. Additional specific entries on a topic can be easily found by following the cross-references in a top-down manner. Several figures and tables are provided to enhance the comprehension of the topics and a list of acronyms helps to locate the full terminologies. The bibliography offers suggestions for further reading.

As it was already seen in the first volume of the present book, its guideline is precisely the mathematical model of mechanics. The classical models which we refer to are in fact models based on the Newtonian model of mechanics, on its five principles, i. e. : the inertia, the forces action, the action and reaction, the parallelogram and the initial conditions principle, respectively. Other models, e. g. , the model of attraction forces between the particles of a discrete mechanical system, are part of the considered Newtonian model. Kepler's laws brilliantly verify this model in case of velocities much smaller than the light velocity in vacuum. The non-classical models are relativistic and quantic. Mechanics has as object of study mechanical systems. The first volume of this book dealt with particle dynamics. The present one deals with discrete mechanical systems for particles in a number greater than the unity, as well as with continuous mechanical systems. We put in evidence the difference between these models, as well as the specificity of the corresponding studies; the generality of the proofs and of the corresponding computations yields a common form of the obtained mechanical results for both discrete and continuous systems. We mention the thoroughness by which the dynamics of the rigid solid with a fixed point has been presented. The discrete or continuous mechanical systems can be non-deformable (e. g.

Formed of presented papers this volume contains research from the 40th International Conference on Boundary Elements and other Mesh Reduction Methods, recognised as THE international forum for the latest advances in these techniques and their applications in science and engineering. The ongoing success of this series is a result of the strength of research being carried out all over the world and the coverage has continually evolved in line with the latest developments in the field. The books originating from this conference series constitute a record of the development of BEM/MRM, running from the initial successful development of boundary integral techniques into the boundary element method, a technique that eliminates the need for an internal mesh, to the recent and most sophisticated Mesh Reduction and even Meshless Methods. Since these methods are used in many engineering and scientific fields the 2017 book, Boundary Elements and other Mesh Reduction Methods, like the series before, will be of great interest to those working within the areas of numerical analysis, boundary elements and meshless methods. The research papers included in this volume cover: Advanced formulations; Advanced meshless and mesh reduction methods; Structural mechanics applications; Solid mechanics; Heat and mass transfer; Electrical engineering and electromagnetics; Computational methods; Fluid flow modelling; Damage mechanics and fracture; Dynamics and vibrations; Engineering applications; Interfacing with other methods; Coupling with design and manufacturing; Solution of large systems of equations.

In April 2007, the Deutsche Forschungsgemeinschaft (DFG) approved the Priority Program 1324 "Mathematical Methods for Extracting Quantifiable Information from Complex Systems." This volume presents a comprehensive overview of the most important results obtained over the course of the program. Mathematical models of complex systems provide the foundation for further technological developments in science, engineering and computational finance. Motivated by the trend toward steadily increasing computer power, ever more realistic models have been developed in recent years. These models have also become increasingly complex, and their numerical treatment poses serious challenges. Recent developments in mathematics suggest that, in the long run, much more powerful numerical solution strategies could be derived if the interconnections between the different fields of research were systematically exploited at a conceptual level. Accordingly, a deeper understanding of the mathematical foundations as well as the development of new and efficient numerical algorithms were among the main goals of this Priority Program. The treatment of high-dimensional systems is clearly one of the most challenging tasks in applied mathematics today. Since the problem of high-dimensionality appears in many fields of application, the above-mentioned synergy and cross-fertilization effects were expected to make a great impact. To be truly successful, the following issues had to be kept in mind: theoretical research and practical applications had to be developed hand in hand; moreover, it has proven necessary to combine different fields of mathematics, such as numerical analysis and computational stochastics. To keep the whole program sufficiently focused, we concentrated on specific but related fields of application that share common characteristics and as such, they allowed us to use closely related approaches.