Collins Cambridge IGCSETM Co-ordinated Sciences Biology provides full coverage of all core and supplement Biology topics in the revised syllabus. Carefully developed features including questions, worked examples, key terms and more allow students to build firm scientific knowledge, develop practical skills and approach exams with confidence. Exam Board: Cambridge Assessment International Education For examination from 2025 Full coverage of the Biology content of the Cambridge IGCSE Co-ordinated Sciences syllabus (0654) for examination from 2025 All extended material covered and clearly differentiated Written by experienced authors who are specialists in their field Packed with questions throughout to check understanding and confirm knowledge Worked examples provide support and scaffolding Key terms and end of topic checklists allow students to check their progress Investigative tasks develop students' practical science skills Practice questions with example answers and comments help students learn how to answer questions well and hone their technique 'Science in Context' boxes deepen students' understanding of the science, how it is used and why it matters, sparking curiosity Further carefully developed features include supportive tips, knowledge checks, glossary and learning objectives to provide a clear, engaging resource for students Answers provided to support self-assessment and reflection A dedicated book for each science to keep course manageable and easy to use We are working with Cambridge Assessment International Education towards endorsement of this resource.

The volumes in this set, originally published between 1913 and 1997, draw together research by leading academics in the area of evolution and provide a rigorous examination of related key issues. The collection examines evolution from a broad range of disciplines, from the anthropological development of modern society, to the scientific examinations of cellular and genetic evolution. The collection includes volumes across the disciplines of biology, natural history, anthropology, sociology and religion. The 15 books that comprise this collection include rigorous examinations into the psychological evolution of the brain, philosophical and theological examinations of evolution, analysis of genetic and cellular evolution, discussions of Darwinian theory, the affect of survival of the fittest from both genetic and political standpoints and examinations into the affinity between man and ape. This collection brings back into print a collection of insightful and detailed books on the diverse subject of evolution and will be a must have resource for academics and students, not only of biology and anthropology, but of history, psychology and religion.

Preclinical Drug Development, Second Edition discusses the broad and complicated realm of preclinical drug development. Topics range from assessment of pharmacology and toxicology to industry trends and regulatory expectations to requirements that support clinical trials. Highlights of the Second Edition include: Pharmacokinetics Modeling and simulation Formulation and routes of administration Toxicity evaluations The assessment of drug absorption and metabolism Interspecies scaling Lead molecule selection and optimization via profiling Screening using in silico and in vitro toxicity evaluations The book also includes case studies on preclinical pharmacokinetic-pharmacodynamic modeling and simulation in drug development, a review of ICH preclinical guidelines, and experimental methods used to study membrane drug transport and metabolism. This guide is a fundamental resource for medicinal chemists, biologists, and other specialists in the drug development sciences.

A fascinating look at what’s rattling around in your skull Neuroscience For Dummies introduces you to the mind-boggling study of the human brain. It tracks to the content of a typical introductory neuroscience class at the college level —and it’s perfect for anyone curious about what makes us tick. New technologies and an explosion of research have completely transformed our understanding of memory, depression, the mind-body connection, learning, and genetics. This updated edition—still in classic, beginner-friendly Dummies style—covers the latest research advances and technologies in the field of neuroscience. Put some knowledge about the brain into your brain. Grasp the basic concepts and applications of neuroscience Understand the brain’s structure and function Explore how the brain impacts memory, learning, and emotions Discover how the brain is connected with other physical systems For students and general readers alike, Neuroscience For Dummies is a great way to understand what’s going on inside our heads.

This book bridges the gap between theoretical concepts and their implementations, especially for the high-performance structures/components related to advanced composite materials. This work focuses on the prediction of various structural responses such as deformations, natural frequencies etc. of advanced composites under complex environments and/or loading conditions. In addition, it discusses micro-mechanical material modeling of various advanced composite materials that involve different structures ranging from basic to advanced, such as beams, flat and curved panels, shells, skewed, corrugated, and other materials, as well as various solution techniques via analytical, semi-analytical, and numerical approaches. This book: Covers micro-mechanical material modeling of advanced composite materials Describes constitutive models of different composite materials and kinematic models of different structural configuration Discusses pertinent analytical, semi-analytical, and numerical techniques Focusses on structural responses relating to deformations, natural frequencies, and critical loads under complex environments Presents actual demonstrations of theoretical concepts as applied to real examples using Ansys APDL scripts This book is aimed at researchers, professionals, and graduate students in mechanical engineering, material science, material engineering, structural engineering, aerospace engineering, and composite materials.

Adopting a multidisciplinary approach with input from physicists, researchers and medical professionals, this is the first book to introduce many different technical approaches for the visualization of microcirculation, including laser Doppler and laser speckle, optical coherence tomography and photo-acoustic tomography. It covers everything from basic research to medical applications, providing the technical details while also outlining the respective strengths and weaknesses of each imaging technique.
Edited by an international team of top experts, this is the ultimate handbook for every clinician and researcher relying on microcirculation imaging.

The way we currently produce our food is damaging both to ourselves and our planet: we need to create gardens, woodlands and farms which are in harmony with nature. Though all natural ecosystems provide excellent examples to follow, Plants For a Future specifically focuses on edible species, suggesting a wide variety of easily grown perennials and self-seeding annuals which produce delicious and healthy food. Describing edible and other useful plants, both native to Britain and Europe, and from other temperate areas around the world, Plants For a Future includes those suitable for: the ornamental garden, the lawn, shady areas, ponds, walls, hedges, agroforestry and conservation. It offers alternative methods of growing these plants in ways that are in harmony with the local environment and can help to improve the overall health of the planet. In his thoroughly useful book, Ken Fern shares his experiments and successes in growing herbs, vegetables, flowers, shrubs and trees. Packed with information, personal anecdotes and detailed appendices and indexes, this pioneering book takes gardening, conservation and ecology into a new dimension.

The Laboratory Animal Pocket Reference Series discusses procedures that ensure laboratory animals receive the best, most humane, and most responsible care possible. The 17 volumes are compact. The contents of each includes important biological features, husbandry, management, veterinary care, regulatory concerns, and commonly used and new procedures, as well as an invaluable list of suppliers. Each book in the series can be purchased individually or as part of the set.

Molluscs comprise the second largest phylum of animals (after arthropods), occurring in virtually all habitats. Some are commercially important, a few are pests and some carry diseases, while many non-marine molluscs are threatened by human impacts which have resulted in more extinctions than all tetrapod vertebrates combined. This book and its companion volume provide the first comprehensive account of the Mollusca in decades. Illustrated with hundreds of colour figures, it reviews molluscan biology, genomics, anatomy, physiology, fossil history, phylogeny and classification. This volume includes general chapters drawn from extensive and diverse literature on the anatomy and physiology of their structure, movement, reproduction, feeding, digestion, excretion, respiration, nervous system and sense organs. Other chapters review the natural history (including ecology) of molluscs, their interactions with humans, and assess research on the group. Key features of both volumes: up to date treatment with an extensive bibliography; thoroughly examines the current understanding of molluscan anatomy, physiology and development; reviews fossil history and phylogenetics; overviews ecology and economic values; and summarises research activity and suggests future directions for investigation. Winston F Ponder was a Principal Research Scientist at The Australian Museum in Sydney where he is currently a Research Fellow. He has published extensively over the last 55 years on the systematics, evolution, biology and conservation of marine and freshwater molluscs, as well as supervised post graduate students and run university courses. David R. Lindberg is former Chair of the Department of Integrative Biology, Director of the Museum of Paleontology, and Chair of the Berkeley Natural History Museums, all at the University of California. He has conducted research on the evolutionary history of marine organisms and their habitats on the rocky shores of the Pacific Rim for more than 40 years. The numerous elegant and interpretive illustrations were produced by Juliet Ponder.

Neurological Complications of Systematic Cancer and Antineoplastic Therapy, Second Edition provides an expanded, updated and in-depth review of common manifestations related to neurology that occur in patients with systemic cancer. These include brain metastases, spinal cord compression, cerebrovascular events, and leptomeningeal disease. The book also discusses neurological complications related to treatments such as radiation and chemotherapy and is an essential reference for the practicing neurologist and oncologist. Sections in this new release cover the pathophysiology and molecular biology of cancer and the metastatic phenotype, Metastatic spread to cranial and peripheral nerves and brachial and lumbosacral plexuses, Metabolic and nutritional disorders, CNS infections, Neurological complications of immunotherapy and bone marrow transplants, Neurological complications of new molecular agents and immuno-modulatory drugs, and more.

1. Discusses implications of COVID on education, environment, and lifestyle 2. Elucidates life-style transformation strategy to counter COVID 3. Focuses on transformative strategy to overcome COVID impact

An expert palaeoarchaeologist reveals how our understanding of the evolution of our species has been transformed by momentous discoveries and technological advancements. Who are we? How do scientists define Homo sapiens, and how does our species differ from the extinct hominins that came before us? This illuminating book explores how the latest scientific advances, especially in genetics, are revolutionizing our understanding of human evolution. Paul Pettitt reveals the extraordinary story of how our ancestors adapted to unforgiving and relentlessly changing climates, leading to remarkable innovations in art, technology and society that we are only now beginning to comprehend. Drawing on twenty-five years of experience in the field, Paul Pettitt immerses readers in the caves and rockshelters that provide evidence of our African origins, dispersals to the far reaches of Eurasia, Australasia and ultimately the Americas. Popular accounts of the evolution of Homo sapiens emphasize biomolecular research, notably genetics, but this book also draws from the wealth of information from specific excavations and artefacts, including the author's own investigations into the origins of art and how it evolved over its first 25,000 years. He focuses in particular on behaviour, using archaeological evidence to bring an intimate perspective on lives as they were lived in the almost unimaginably distant past.

Our Human Planet summarizes the findings of the four working groups and serves as a reference guide to the four main volumes in the MA series. It presents the key findings of each of the working groups, and meets the needs of policy makers and other professionals.
The summary also provides an overview of the framework used by the assessment, and will serve as a guide for assessment, planning, and management for the future.

Fungi is a richly detailed and beautifully illustrated book which tells you everything you need to know about these fasciating organisms. Fungi are an indispensable part of the great chain of life: more than 90% of the world's plant species depend on them for their nutrition. There are believed to be about 1.5 million species, thriving in virtually every habitat, from temperate to tropical, Antarctic to marine. Using beautifully coloured illustrations, this book dips into the whole range, showcasing the unusual, the familiar, the poisonous and the delicious, and sharing the stories of puffballs, deadly webcaps and devils' fingers, among others. Some are cultivated for use in different cuisines, while others are heralded for their hallucinogenic properties, or valued for use in medicine. Essential information on distribution, uses and growth partnerships is included for each species featured, as well as stunning. Weird, alluring and mysterious - get to know what makes mushrooms magic in this handy, colourful book.

A systematic overview of the mechanisms of apomixis and methodology for apomixis research. A reassessment of apomixis at the species level in angiosperm families. Tables summarizing relevant information on apomixis. Analyses occurrences of apomixis in phylogenetic and evolutionary contexts. Outlines the molecular basis and biotechnological perspective of apomixis breeding.

'Intimate and thoughtful... Exciting... [A] sweeping evolutionary history.' Science The author of the bestselling Your Inner Fish gives us a brilliant, up-to-date account of the great transformations in the history of life on Earth. This is a story full of surprises. If you think that feathers arose to help animals fly, or lungs to help them walk on land, you'd be in good company. You'd also be entirely wrong. Neil Shubin delves deep into the mystery of life, the ongoing revolutions in our understanding of how we got here, and brings us closer to answering one of the great questions - was life on earth inevitable...or was it all an accident?

The evolution of a classic The new 12th edition of Introduction to Genetic Analysis takes this cornerstone textbook to the next level. The hallmark focuses on genetic analysis, quantitative problem solving, and experimentation continue in this new edition while incorporating robust updates to the science. Introduction to Genetic Analysis is now supported in Achieve, Macmillan's new online learning platform. Achieve is the culmination of years of development work put toward creating the most powerful online learning tool for biology students. It houses all of our renowned assessments, multimedia assets, e-books, and instructor resources in a powerful new platform.

In the seventeenth century, even the most elaborate and fashionable gardens had areas set aside for growing herbs, fruit, vegetables and flowers for domestic use, while those of more modest establishments were vital to the survival of the household. This was also a period of exciting introductions of plants from overseas. Using manuscript household manuals, recipe books and printed herbals, this book takes the reader on a tour of the productive garden and of the various parts of the house - kitchens and service rooms, living rooms and bedrooms - to show how these plants were used for cooking and brewing, medicines and cosmetics, in the making and care of clothes, and finally to keep rooms fresh, fragrant and decorated. Recipes used by seventeenth-century households for preparations such as flower syrups, snail water and wormwood ale are also included. A brief herbal gives descriptions of plants that are familiar today, others not so well known, such as the herbs used for dyeing and brewing, and those that held a particular cultural importance in the seventeenth century. Featuring exquisite coloured illustrations from John Gerard's herbal of 1597 as well as prints, archival material and manuscripts, this book provides an intriguing and original focus on the domestic history of Stuart England.

Humans are the only mammals to walk on two, rather than four, legs. From an evolutionary perspective, this is an illogical development, as it slows us down. But here we are, suggesting there must have been something tremendous to gain from bipedalism. First Steps takes our ordinary, everyday walking experience and reveals how unusual and extraordinary it truly is. The seven-million-year-long journey through the origins of upright walking shows how it was in fact a gateway to many of the other attributes that make us human-from our technological skills and sociality to our thirst for exploration. DeSilva uses early human evolution to explain the instinct that propels a crawling infant to toddle onto two feet, differences between how men and women tend to walk, physical costs of upright walking, including hernias, varicose veins and backache, and the challenges of childbirth imposed by a bipedal pelvis. And he theorises that upright walking may have laid the foundation for the traits of compassion, empathy and altruism that characterise our species today and helped us become the dominant species on this planet.

Understanding the human mind and how it relates to the world of experience has challenged scientists and philosophers for centuries. How do we even begin to think about 'minds' that are not human? That is the question explored in this ground-breaking book. Award-winning science writer Philip Ball argues that in order to understand our own minds and imagine those of others, we need to move on from considering the human mind as a standard against which all others should be measured. Science has begun to have something to say about the properties of mind; the more we learn about the minds of other creatures, from octopuses to chimpanzees, to imagine the potential minds of computers and alien intelligences, the more we can begin to see our own, and the more we can understand the diversity of the human mind, in the widest of contexts. By understanding how minds differ, we can also best understand our own.

Few, if any, genes have had the same level of impact on the field of evolutionary-developmental biology (evo-devo) as the Hox genes. These genes are renowned for their roles in patterning the body plans and development of the animal kingdom. This is complemented by the distinctive organisation of these genes in the genome, with them frequently being found as clusters in which gene position is linked to when and where the individual genes are expressed, particularly during embryogenesis. This book provides the latest overviews of Hox gene organisation and function for major clades of animals from across the animal kingdom. With the rapidly increasing availability of high-quality whole genome sequences from an ever-expanding range of species, it is becoming increasingly evident that there is great diversity in the organisation of Hox genes. These great strides in genome sequencing are wedded to important developments in our ability to detect expression and disrupt gene function in species that are not traditionally genetically-amenable animals. These technical developments are integrated with wide taxon-sampling in this volume to provide new perspectives on the roles of Hox genes in understanding fundamental issues such as embryo patterning, mechanisms of gene regulation, homology, evolvability, evolutionary novelties, phylogeny, the role of gene and genome duplications in evolution, and ancestral states for major clades of animals. Key features Integrative overviews from major animal groups including, arthropods, vertebrates, echinoderms, mollusks and other spiralians. Perspectives gleaned from the latest genome sequence and gene expression data. Individual chapters written by world-leading experts in Hox genes and evo-devo in each animal group. Related Titles Scholtz, G., ed. Evolutionary Developmental Biology of Crustacea (ISBN 978-9-0580-9637-1) Mattick, J. & P. Amaral. RNA, The Epicenter of Genetic Information (ISBN 978-0-3675-6778-1) Bard, J. Evolution: The Origins and Mechanisms of Diversity (ISBN 978-0-3673-5701-6)

There has been a global rise in the incidence of chronic illnesses, which may be partially attributed to the lengthening of the average human lifespan. Functional foods and nutraceuticals have a potential role to play in the development and maintenance of health. They can assist the body in its battle against inflammation and chronic illnesses. Molecular Mechanisms of Action of Functional Foods and Nutraceuticals for Chronic Diseases addresses the effects and mechanism of functional foods in relation to chronic diseases such as obesity, cardiovascular diseases, diabetes, cancer, etc. This volume, like the companion Applications of Functional Foods and Nutraceuticals for Chronic Diseases, inspires new thought processes and a paradigm shift in research and development. Key Features: Discusses the molecular mechanism of action, the range of toxicities exerted by these food components for functional foods for addressing chronic conditions Enhances scientists and industrial personnel knowledge of functional foods and in the management of chronic diseases Presents research on the role of functional foods/nutraceuticals in preventing and treating chronic diseases through epigenetic modulation. Explores various subjects such as epigenetics, immunological, metabolic, technological and neurodenerative aspects affected by functional foods in chronic diseases The world's leading wellness centers for chronic diseases are using functional foods and nutraceuticals in their practice and discovering their useful applications, and this second of two related books is another great reference for practitioners, scientists, and clinicians in the management of chronic diseases. Contributors hail from different geographical locations around the world and have many years of research and scholarly experience in functional foods, nutraceuticals, and biology.

In this text, the small team of expert authors presents the field in a comprehensive and accessible manner that is well suited for students and junior researchers.
The result is a highly readable and systematically structured introduction to antimicrobial peptides, their structure, biological function and mode of action. The authors point the way towards a rational design of this potentially highly effective new class of clinical antibiotics on the brink of industrial application. They do this by discussing their design principles, target membranes and structure-activity relationships. The final part of the book describes recent successes in the application of peptides as anticancer agents.

An accessible and thought-provoking introduction to timespans in the natural world, featuring more than 80 beautifully designed diagrams. Which organisms live the longest? How does the natural world recover from fire? How long do eggs take to hatch? What are the world's fastest and slowest growing plants? Which species invest the most in parental care? How Nature Keeps Time discovers the natural world's most important and intriguing patterns of time. Beautifully designed with stunning colour photography and more than 80 reader-friendly charts and diagrams, this witty book examines a broad range of species from across the world and throughout time. From the lifecycle of immortal jellyfish and identifying the perfect amount of time for a 'good sleep' to mass extinction and the destruction of the coral reef, Helen Pilcher tackles highly relevant and fascinating topics in this deeply entertaining read.