Advances in Biomembranes and Lipid Self-Assembly, Volume 37 provides a comprehensive compilation of recent developments in a field that is in a state of rapid growth as new experimental and theoretical techniques are used on many problems, both old and new. Topics covered include related applied areas, such as atmospheric science, astrophysics, surface physics, and laser physics, with timely articles written by experts. New chapters in this updated release include Engulfment of particles by vesicles containing curved membrane proteins coupled with active cytoskeletal forces, Interaction of cells with different types of nanostructured surfaces, Solid-supported lipid bilayer formation by solvent exchange, and more.

Advances in Applied Microbiology, Volume 122 continues the comprehensive reach of this widely read and authoritative review source in microbiology. Users will find invaluable references and information on a variety of areas relating to the topic of microbiology. This release includes updates on BioMateriOME: to understand microbe-material interactions within sustainable, living architectures.

African Flora to Fight Bacterial Resistance, Part Two: The Best Source of Herbal Drugs and Pharmaceuticals, Volume 107 offers detailed information on the best African medicinal plants that could be useful for the development of efficient herbal drugs, as well as the best phytochemicals that could be explored as potential pharmaceuticals to efficiently tackle bacterial drug resistance. The book provides knowledge on ethnomedicinal uses of the identified plants, their pharmacological potency, and their phytochemistry. Chapters cover Phytochemistry and antibacterial potential of the genus Allanblackiam Phytochemistry and antibacterial potential of the genus Beilschmedia, Phytochemistry and antibacterial potential of the genus Fagara, and more. Other sections explore Harungana madagascariensis as a source of antibacterial agents, Hypericum roeperianum as a source of antibacterial agents, Myristica fragrans as a potential source of antibacterial agents, Phytochemistry and antibacterial potential of the genus Nauclea, Picrilima nitida as a potential source of antibacterial agents, Uapaca togoensis as a potential source of antibacterial agents, and much more.

Control of Cell Cycle & Cell Proliferation, Volume 135 in the Advances in Protein Chemistry and Structural Biology series, highlights new advances, with this new volume presenting chapters on a variety of timely topics, including Exploiting pivotal mechanisms behind the senescence-like cell cycle arrest, Viral infection on through Cell Cycle Regulation, Analyzing drug resistant mutation in CDK4 gene and identification of potential inhibitors through structure based virtual screening approach, Controlling cell proliferation by targeting CDK6 using drug repurposing approach, Cdk Regulators: Growth Arrest or Apoptosis? Scenarios in normal and cancerous cells, Targeting cell cycle signaling pathways for cancer therapy, and much more. Other sections focus on The role of the nucleolus in regulating cell cycle, Chromatin regulators in DNA replication and genome stability maintenance during S-phase, Role of macrophage in cancer cell progression and targeted immunotherapies, Anti-cancer drug molecules targeting cancer cell cycle and proliferation, Cellular signals integrate cell cycle and metabolic control in cancer, Therapeutic targeting and proliferation of HSCs by small molecules and biologicals, Mechanism of cell cycle regulation and cell proliferation during human viral infection, and Cyclin-dependent kinases: Role, regulation, and therapeutic targets in cancer.

Profiles of Drug Substances, Excipients, and Related Methodology, Volume 48 encompasses review articles and database compilations that fall within one or more of the following five broad categories: Physical Profiles of Drug Substances and Excipients; Analytical Profiles of Drug Substances and Excipients; ADME Profiles of Drug Substances and Excipients; Methodology Related to the Characterization of Drug Substances and Excipients; Methods of Chemical Synthesis. There is no comparable book series that gives this crucial information in such a timely and relevant manner. The volume offers in-depth profiles of five drug compounds: Brimonidine, Cristine, Remdesivir, Vandetanib, and Lapatinib. It also includes an additional chapter that discusses Pharmaceutical-Based Cosmetic Serums.

Advances in Virus Research, Volume 115, the latest release in this comprehensive serial that highlights new advances in the field, includes updates on a variety of timely topics, including Plant viral nanotools, Mycoviruses, Rift Valley Fever virus entry and infection, and more.

Biochemical Pathways and Environmental Responses in Plants: Part C, Volume 683 in the Methods in Enzymology series, highlights advances in the field. with this new volume presenting chapters on topics including Preparation of hydroxycinnamoyl-CoA thioesters using recombinant 4-coumarate:coenzyme A ligase (4CL) for characterization of BAHD acyltransferases, Near-real time determination of BAHD acyl-coA transferase reaction rates, Bioinformatic tools for protein structure prediction and for molecular docking applied to enzyme active site analysis, Computational and biochemical methods to measure the activity of carboxysomes and protein organelles in vivo, Dirigent Proteins Family Function and Structure, Three-in-One Method for High-throughput plant multi-omics, amongst other timely topics. Additional sections cover Analysis of isoprenyl-phosphates by liquid chromatography-mass spectrometry, Lignin/Lignan Biosynthesis Structure/Function, Comparison of TLC, HPLC, and direct infusion mass spectrometry methods for identification and quantification of diacylglycerol molecular species, Plant sphingolipid analysis, RNA-seq analysis of alternative pre-mRNA splicing mediated by photoreceptors in Physcomitrium patens, and much more.

Ionizing Radiation and the Immune Response, Volume 376, Part A reviews the latest updates on the immune response induced by ionizing radiations. Sections discuss the role of specific immune cells (macrophage, lymphocyte, NK cells...) and describe the effect of modern radiotherapy techniques (TRT, minibeams, flash-RT, proton therapy, heavy ions...) on immune response. Sample chapters cover NK functions in radio-induced immune response, TRT and immune response, Radio-induced immune response and lipid metabolism, Effect of protons and heavy ions on immune response, Effect of flashtherapy and mini beam on immune response, Radio-induced lymphopenia, CT to potentiate radio-induced immune response, and much. Other sections focus on the Effect of low dose radiation on radio-induced immune response, Role of Dendritic cells in radiation-induced immune response, Relationship between the tumor microenvironment and the efficacy of the radiotherapy/immunotherapy combination+A23, Biomarkers of radiation induced response to optimize radio-immunotherapy combination.

Genome Engineering, Volume 52 in the Methods in Microbiology series, highlights new advances in the field with this new volume presenting interesting chapters written by an international board of authors. Topics covered include Whole genome transplantation in Mollicutes, Natural transformation as a tool in Acinetobacter baylyi: evolution by amplification of gene copy number, Natural transformation as a tool in Acinetobacter baylyi: streamlined engineering and mutational analysis, Methods to characterize cryptic biosynthetic gene clusters in Streptomyces, Genome engineering in bacteria: current and prospective applications, Tools for activation and identification of cryptic biosynthesis pathways in Streptomyces.

Cell Polarity in Development and Disease, Volume 154 in the Methods in Cell Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Cell polarity in the protist-to-animal transition, Polarized actin networks in development: Case studies from Drosophila, Protein clustering and cell polarization, Polarity in the Drosophila female germline, Context Matters: Mechanisms governing epithelial polarization in C. elegans, Epithelial polarity in the fly: Principles and diversity, Polarizing epithelial expulsion and expulsion driven by mispolarization, The Role of Apical-Basal Polarization in the Mammalian First Cell Fate Decision, and much more.

Stromal Signaling in Cancer, Volume 154 in the Advances in Cancer Research series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics surrounding cancer research. Each chapter is written by an international board of authors.

Integrated Methods in Protein Biochemistry: Part C, Volume 679 in the Methods in Enzymology series, highlights new advances in the field with this new volume presenting interesting chapters on a variety of topics, including NanoBiT-based methods to monitor the activation and modulation of RTKs, The interplay of G-protein ss? subunit and PLC-ss enzyme in PIP2 hydrolysis and downstream signaling, Biochemical Analysis of Protein-Protein Interfaces underlying the regulation of Bacterial Secretion Systems, Probing the structure and function of N-acetylmannosamine-6-phosphate 2-epimerase, Spectroscopic analysis of cysteine dioxygenase: a mammalian thiol-dioxygenase, DeGlyPHER: MS-based analysis of viral spike N-glycoforms, and more. Other sections cover Covalent protein painting: MS-based protein footprinting, Characterization of GPCR signaling complexes using negative-staining electron microscopy, Probing protein misfolding and dissociation with free electron laser, Optimized protocol for the characterization of Cas12a activities, Proximity proteomics for the identification and characterization of extracellular vesicles, Functional characterization of lytic polysaccharide monooxygenases (LPMOs), Characterization of RRE domain in RiPP biosynthesis, The Preparation of Recombinant Arginyltransferase 1 (ATE1) for Structural and Biophyiscal Characterizations, Testing anti-cancer drugs with Holographic Incoherent-light-source Quantitative Phase Imaging, and more.

African Flora to Fight Bacterial Resistance, Part One: Standards for the Activity of Plant-Derived Products offers a glimpse into the potential of African medicinal plants to fight bacterial infections, with an emphasis on bacterial drug resistance. Sample chapters cover the Global Burden of bacterial infections and drug resistance, Bacterial drug resistance towards natural products, Harvesting and Processing Medicinal plants for antibacterial testing, Screening methods for antibacterial agents from plant source, Established antibacterial drugs from plants, Potential of African medicinal plants against Enterobacteria: classification of plants antibacterial agents, and much more. Based on collected data, the book offers a rationale classification basis for the antibacterial activity of plant-based products. General knowledge of state-of-the-art of drug resistance is globally described, with the book clearly identifying the best African medicinal plants that could be useful for the development of efficient herbal drugs, as well as the best phytochemicals that could be explored as potential pharmaceuticals.

Advances in Microbial Physiology serial highlights new advances in the field with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

Wnt Signaling in Development and Disease, Volume 153 in the Current Topics in Developmental Biology series, highlights new advances in the field, with this new volume presenting interesting chapter on topics such as The cell biology of Wnt gradient formation, Approaches to visualize and trace Wnt signaling in vitro and in vivo, WNT signaling and the regulation of pluripotency, Wnt/Frizzled signaling in stem cells in development and cancer, Wnt signaling in hydra development and regeneration, Wnt signaling in whole body regeneration, Role of planar cell polarity and Wnt signaling in left-right asymmetry, Wnt signaling in axial progenitors, and more. Other chapters cover Wnt signaling in Xenopus neural development, Wnt signaling in hematopoietic stem cell development, Wnt signaling and the maintenance and regeneration of the gut epithelium, Wnt signaling in the skeleton as a basis for Wnt-based regenerative medicine, and Non-canonical Wnt5a-Ror signaling: Insights from human congenital disorders and cancer.

Contaminants of emerging concern in the marine environment: current challenges in marine pollution reviews the available data in relation to contaminants of emerging concern (CECs) in the marine environment: main sources, transport pathways, distribution in seawater and sediments, bioaccumulation, and biological effects. Each chapter recaps the most relevant information about the main groups of CECs, describing the particularities and specificities of each group and focusing on the most relevant individual contaminants. CECs are not regulated substances, and therefore not considered in national and international monitoring programs, even though they may have a potential impact on the environment due to their continuous input, relative persistence, and/or toxicity. CECs are relevant not only in continental and coastal areas close to their main sources, but also in the open sea, because some of them are likely to be transported long distances through air deposition or absorbed into particulate material. The persistence of many degradable substances in the marine environment increases when they are absorbed into particulate material/sediments and/or when they are subjected to anaerobic conditions that slow down the degradation kinetic of many contaminants. Bioaccumulation of several CECs has been confirmed in different coastal organisms; however, in general, the information available (species and trophic levels considered) is very limited because most studies are mainly focused on specific coastal areas. This book offers useful information about not regulated contaminants that are not considered in international monitoring programs but have potential impacts in coastal and open-sea areas. Therefore reading the book will allow them to improve their view about the real impact of current-use contaminants in the marine environment.

Essential Oils: Extraction, Characterization and Applications covers sixteen essential oils from different herbal and aromatic plants, including production, composition and extraction techniques such as distillation, chemistry and properties, characterization and applications. The book also presents their safety, toxicity and regulation, alongside trade, storage, stability and transport concepts. Essential oils in plants, extraction and analysis, and current trends in the use of essential oils, like aroma therapy, agro-food and non-food usage are thoroughly explored. Remaining chapters are dedicated to different essential oils, including lavender, peppermint, sandalwood, citrus, eucalyptus, tea tree, clove, ginger, cinnamon, nutmeg, rosewood, juniper and pine, patchouli, clary, and more. Edited by a global team of experts in essential oils, this book is designed to be a practical tool for the many diverse professionals who develop and market essential oils.

Developing Sustainable and Health Promoting Cereals and Pseudocereals: Conventional and Molecular Breeding reviews the most recent developments in the fields of cereal and pseudocereal breeding, with particular emphasis on the latest biotechnological techniques likely to lead to breakthrough changes in plant breeding. The book provides comprehensive information on the use of genetic resources or pre-breeding activities to improve health-related properties of cereals and pseudocereals. The text also explores targeted field-management practices and the latest in biotechnological methodologies, and offers a cohesive overview necessary for understanding the potential impacts and benefits of improved production of cereals and pseudocereals with high-nutritional value.

Advances in Clinical Chemistry, Volume 113, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. The serial discusses the latest and most up-to-date technologies related to the field of clinical chemistry with sections in this release focusing on Biosensors for saliva biomarkers, Biochemistry and pathophysiology of the Transient Potential Receptor Vanilloid 6 (TRPV6) calcium channel, Protein Glycation in Diabetes Mellitus, Biomarkers of Oxidative Stress and Reproductive Complications, Cortisol: Analytical and Clinical Determinants, and Hemophilia A: Emicizumab monitoring and impact on coagulation testing.

Hormones and Epigenetics, Volume 122, the latest release in the Vitamins and Hormones series, highlights new advances in the field, with this new volume presenting timely, interesting chapters written by an international board of authors.

Metabotropic Glutamate Receptors in Psychiatric and Neurological Disorders, Volume 168 in the International Review of Neurobiology series, highlights advances in the field, with this new volume presenting interesting chapters on topics such as mGlu receptors in Parkinson's disease, Metabotropic glutamate receptors in estradiol-mediated motivated behaviors in females, mGlu regulation of sleep, Implications for sleep disruptions in psychiatric disorders, Mechanisms of mGlu receptor trafficking; alterations by methamphetamine, Group I mGlu and cocaine seeking, The role of mGlu receptors in fear and anxiety, Regulation of Alcohol Consumption, Reward, Dependence, and Perception by Metabotropic Glutamate Receptor Signaling, and mGlu5 as a biomarker for psychiatric disorders.