This 4th edition of the "Mouse Manual"-Manipulating the Mouse Embryo-appears 28 years after the first edition and once again is the definitive reference source on mouse development, transgenesis techniques, and molecular biology. Authors Richard Behringer, Marina Gertsenstein, Kristina Nagy, and Andras Nagy-pre-emininent leaders in their fields-have reorganized and updated this edition to include new information and protocols on: * assisted reproduction techniques for sperm and embryo cryopreservation * generation of induced pluripotent stem cells * isolation, generation, and transplantation of spermatogonial stem cell lines * in utero electroporation of gene constructs into post- implantation embryos * vibratome sectioning of live and fixed tissues for imaging thick tissue sections * whole-mount fluorescent staining methods for three-dimensional visualization. Techniques regarding recombinant DNA technology and mouse embryonic development from the previous editions have been updated and recast, as has the wealth of information on mouse laboratory strains, mouse housing and breeding, surgical procedures, assisted reproduction, handling of embryos, and micromanipulation setups. The first edition of Manipulating the Mouse Embryo appeared in 1986 as an outgrowth of Cold Spring Harbor Laboratory courses on the molecular embryology of the mouse held in the early 1980s, and authors of the first two editions included Brigid Hogan, Rosa Beddington, Frank Costantini, and Liz Lacy. Mouse embryo manipulation techniques have developed exponentially since the first edition, but then, as now, Manipulating the Mouse Embryo remains the essential practical and theoretical guide for anyone working with mice-students, lab technicians, and investigators.

Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. Ninety-eight of the chief complaints and disorders you're most likely to encounter in the ED!A clear, concise guide for clinicians new to the Emergency Department A Doody's Core Title for 2015! Written by authors who are practicing emergency physicians and emergency medicine educators, Clinical Emergency Medicine distills the entire content of the emergency medicine curriculum into less than one hundred succinct, clinically relevant chapters. This unique book is intended to guide you through what you must know and be able to do during an actual shift and give you a better understanding of the issues and problems you will face while working in the Emergency Department. Featuring a consistent, find-it-now design, Clinical Emergency Medicine delivers concise, must-know information on ninety-eight chief complaints and disorders, ranging from asthma and chest pain to fever and poisoning. Each chapter begins with Key Points, followed by an Introduction, Clinical Presentation (History and Physical Examination), Diagnostic Studies, Medical Decision Making, Treatment and Disposition, and Suggested Reading. Whenever possible, the authors provide practical advice on drug dosing, the medical decision-making thought process, treatment plans, and dispositions that will be of value in a clinical environment. Numerous diagnostic algorithms simplify the problem and point you towards a solution. Valuable to medical students, physician assistants, nurse practitioners, and junior level residents, Clinical Emergency Medicine teaches you things that may not have been covered in medical or physician assistant school, but have an important bearing on patient outcomes.

The Year Book of Emergency Medicine brings you abstracts of the articles that reported the year's breakthrough developments in emergency medicine, carefully selected from more than 500 journals worldwide. Expert commentaries evaluate the clinical importance of each article and discuss its application to your practice. There's no faster or easier way to stay informed! Topics covered in the 2012 edition include Trauma, Resuscitation, Cardiovascular Emergencies, Gastrointestinal Emergencies, Infections and Immunologic Disorders, Neurology, and Pediatric Emergency Medicine. Focused, fast, and insightful information for the busy Emergency Room Physician!

Sudden cardiac arrest is the leading cause of death among adults, yet it need not be fatal. Though survival in most communities is very poor, a few communities achieve rates as high as 50%. Why are some communities so successful in snatching life from the jaws of death? "Resuscitate " describes the steps any EMS system can take to improve cardiac arrest survival. It is written for the medical directors, administrative directors, fire chiefs, dispatch directors, and program supervisor who direct and run EMS systems all across the country, and for the EMTs, paramedics, and dispatchers who provide frontline care.

This second edition of "Resuscitate " provides fifteen concrete steps to improve survival. Four steps will lead to rapid improvements at the local level and are relatively easy to implement. Six additional steps are more difficult to implement but also likely to improve survival. The remaining steps recommend changes at the national level.

"Resuscitate " is the official textbook for the Resuscitation Academy, held twice a year in Seattle. Cosponsored by Seattle Medic One, King County EMS, and the Medic One Foundation, the Academy draws attendees from throughout the world for two intensive days of classes, demonstrations, and workshops to acquire the knowledge and tools to improve survival in their own communities. This new edition includes lessons learned from attendees of the Academy as well as from the faculty's evolving thoughts on how to measure performance and improve survival, one community at a time. It also includes an addendum on the Resuscitation Academy (resuscitationacademy.org).

For more than thirty years, Mickey S. Eisenberg M.D., Ph.D., has played a leading role in developing King County, Washington's emergency response to cases of sudden cardiac arrest, a system recognized as among the very best in the nation. He is a professor of medicine at the University of Washington and serves as the medical director of King County Emergency Medical Services.

"If you care about sudden cardiac arrest in your community and how emergency medical services respond to this critical emergency, I can think of no more important book than this."-from the Foreword by Roger D. White, M.D., Mayo Clinic

"Eisenberg has done a remarkable job in articulating the steps to be taken for communities to improve survival from sudden cardiac arrest. "Resuscitate " is a 'best in class' and one of a kind guide that provides inspiration as well as direction in translating resuscitatioin science into practice. It is essential for all those who seek to establish strategies to improve survival and quality of life for cardiac arrest victims whose hearts are 'too young to die.'" -David B. Hiltz, EMT-P Resuscitation Academy Alumni

"This book was transformative to me and to the EMS system in Durham, North Carolina. I read it cover to cover and attended the Resuscitation Academy. Eisenberg and his colleagues gave me the knowledge, the tools, and the inspiration to improve resuscitation in Durham. Step by step we are getting better and more lives are being saved." -Captain David Jacobs, Durham County Fire Department

Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. THE ULTIMATE PRIMER FOR THE CORE CLERKSHIPS, NOW IN FULL COLOR! Everything you need to know to score strong clerkship evaluations Preparation for every core rotation: medicine, surgery, pediatrics, obstetrics and gynecology, neurology, psychiatry, and emergency medicine Answers to commonly asked "pimp" questions Hundreds of full-color illustrations clarify essential concepts and improve retention Advice on presenting cases to attendings How-to guides for common procedures High-yield facts on the diagnosis and treatment of common diseases Sample patient notes, clipboard and note-card patient templates Updated student ratings of popular clinical handbooks, review books, reference texts, and electronic products A STUDENT-TO-STUDENT GUIDE TO THE FUNDAMENTALS OF SURVIVING THE WARDS--DON'T START THE CLINICAL YEARS WITHOUT READING THIS BOOK! APPLY THE PROVEN FIRST AID FORMULA FOR CLERKSHIP SUCCESS!

Emergency physicians, in all practice settings, care for patients with both undifferentiated psycho-behavioral presentations and established psychiatric illness. This reference-based text goes beyond diagnostics, providing practical input from physicians experienced with adult emergency psychiatric patients. Physicians will increase their understanding and gain confidence working with these patients, even when specialized psychiatric back-up is lacking. Behavioral Emergencies for the Emergency Physician is comprehensive, covering the pre-hospital setting and advising on evidence-based practice; from collaborating with psychiatric colleagues to establishing a psychiatric service in your ED. Sedation, restraint and seclusion are outlined. Potential dilemmas when treating pregnant, geriatric or homeless patients with mental illness are discussed in detail, along with the more challenging behavioral diagnoses such as malingering, factitious and personality disorders. This go-to, comprehensive volume is invaluable for trainee and experienced emergency physicians, as well as psychiatrists, psychologists, psychiatric and emergency department nurses and other mental health workers.

The Year Book of Emergency Medicine brings you abstracts of the articles that reported the year's breakthrough developments in emergency medicine, carefully selected from more than 500 journals worldwide. Expert commentaries evaluate the clinical importance of each article and discuss its application to your practice. There's no faster or easier way to stay informed Topics covered in the 2012 edition include Trauma, Resuscitation, Cardiovascular Emergencies, Gastrointestinal Emergencies, Infections and Immunologic Disorders, Neurology, and Pediatric Emergency Medicine. Focused, fast, and insightful information for the busy Emergency Room Physician

Trauma: A Comprehensive Emergency Medicine Approach is a fully illustrated, interdisciplinary overview of trauma. Using both evidence-based approaches and a practical understanding of the emergency department, it gives a broad and in-depth review of trauma care. The entire spectrum of trauma presentations is reviewed from minor soft-tissue injuries through to major life-threatening conditions. Written by over 50 expert contributors, it gives concrete and practical recommendations for evaluation, treatment, consultation and disposition decisions on both common and unusual conditions. Extensive use of photographs, illustrations and key information boxes is used to make the material accessible. Additional sections provide an overview of multiple other issues relating to emergency management of trauma including administrative, nursing, research and legal matters. This book provides an essential reference for anyone who is called upon to provide acute trauma care in the emergency department.

Since the first use of basic life support (BLS) and defibrillation in the pre-hospital setting in Belfast in 1966, few would argue that there have been major improvements in the rate of survival for out-of-hospital cardiac arrests. Indeed, until the widespread introduction of BLS and defibrillators to emergency medical service (EMS) vehicles, an out-of-hospital cardiac arrest would mean certain death. The initial rhythm of a patient in cardiac arrest is predictive of their chances of survival. In this regard, the rhythms with the highest rate of survival to hospital discharge are ventricular fibrillation (VF) and ventricular tachycardia (VT). As VF is a more common presenting rhythm in out-of-hospital cardiac arrest and much of our knowledge of VF is relevant to VT, this book focuses primarily on VF cardiac arrest.

Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. Complete guidance on how to diagnose and treat neurologic emergencies in any acute care setting! "This is an excellent, easy to read, concise review of common presenting neurological symptoms that are often encountered in the emergency department or hospital. The practical nature of this book is evident as the chapters are presented according to patient symptomatology instead of neurological entities. 3 Stars."--Doody's Review Service Uniquely organized by presenting complaint, Neurologic Emergencies helps you quickly identify, evaluate, stabilize, treat, and manage the full range of neurologic symptoms--from dizziness to trauma. Striking the perfect balance between thoroughness and readability, this trusted classic delivers the authoritative guidance you need to ensure the best possible outcomes possible for patients presenting with neurologic emergencies. The Third Edition has been updated with a valuable primer on neuroimaging technologies and includes the latest evidence-based treatment strategies and expert advice. Features: Organized by presenting symptoms, rather than by disease, for unmatched clinical relevance Written by a team of authors highly experienced in managing patients with neurologic complaints Numerous algorithms and tables offer immediate access to critical information Emphasizes patient history, physical exam, and rapid assessment Everything you need to know in the acute care setting: Review of Basic Neuroanatomy,Neuroimaging,Evaluation of a Neurologic Complaint,Altered States of Consciousness and Coma,Acute Focal Neurological Deficit,Acute Weakness,Movement Disorders, Headache;Acute Double Vision, Blindness, and Abnormal Pupils;Neurologic Trauma,Psychogenic Neurologic Problems,Seizures,Syncope,The Dizzy Patient,Neck and Back Pain

Pain management (also called pain medicine) is the discipline concerned with the relief of pain. Acute pain, such as occurs with trauma, often has a reversible cause and may require only transient measures and correction of the underlying problem. In contrast, chronic pain often results from conditions that are difficult to diagnose and treat, and that may take a long time to reverse. Some examples include cancer, neuropathy, and referred pain. Often, pain pathways (nociceptors) are set up that continue to transmit the sensation of pain even though the underlying condition or injury that originally caused pain has been healed. In such situations, the pain itself is frequently managed separately from the underlying condition of which it is a symptom, or the goal of treatment is to manage the pain with no treatment of any underlying condition (e.g. if the underlying condition has resolved or if no identifiable source of the pain can be found.Pain management generally benefits from a multidisciplinary approach that includes pharmacologic measures (analgesics such as narcotics or NSAIDs and pain modifiers such as tricyclic antidepressants or anticonvulsants), non-pharmacologic measures (such as interventional procedures, physical therapy and physical exercise, application of ice and/or heat), and psychological measures (such as biofeedback and cognitive therapy). This new book presents the latest research in this growing field.

Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. All the essentials of critical care in an instant! This concise, yet comprehensive review is the perfect tool to prepare for in-service or licensing exams, for re-certification, or for use as a clinical refresher. Its highly efficient format conveniently condenses and simplifies the most important content, for maximum yield and comprehension-an especially important benefit for facilitating bedside diagnosis in critical care medicine. FEATURES Compact review of key board-type material for specialization in critical care medicine Trusted insights from a writing team of top-name academics and clinicians from one of the country's preeminent critical care divisions Standardized, bulleted format emphasizes key points of epidemiology, pathophysiology, clinical features, differential diagnosis, diagnosis, procedures and treatment, prognosis, plus references Highlights and summarizes key concepts to assure quick absorption of the material and reinforce your understanding of even the most difficult topics Logical chapter organization, arranged by system (cardiology, pulmonary system...) and illness (trauma, burns, poisoning...) to help focus your study and provide quick access to subjects

Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. A comprehensive, hands-on guide that explains how to accurately diagnose abdominal pain -- and treat its underlying causes A Doody's Core Title for 2011! 4 STAR DOODY'S REVIEW "This does a remarkable job of examining and summarizing the most recent diagnostic and therapeutic options for a very difficult yet common complaint. Its strength is in the discussion of best use and limitations of the testing modalities used to diagnose abdominal pain. It is more concise than many other similar texts, and covers the information extremely well."--Doody's Review Service This clinical companion -- written by emergency room physicians for emergency room physicians -- takes you through all of the must-know management strategies for acute and chronic abdominal pain and its etiology. In its all-inclusive overview of abdominal pain-related conditions such as urinary tract infection and diverticulitis, the book includes only those insights that are most useful for busy ER physicians. This essential, high-yield approach carries over to a chapter format that features quick-hit bulleted lists of key clinical facts, along with a step-by-step review of management guidelines. You'll also find an abundance of clinically relevant CT and ultrasound scans, plus criteria for their interpretation.

Current Essentials of Emergency Medicine. C. Keith Stone, MD. Roger L. Humphries, MD. . . CURRENT ESSENTIALS OF EMERGENCY MEDICINE is a unique, high-compression quick reference for the wards and the clinic!. . In-a-nutshell information on the diagnosis and treatment of 500 diseases, disorders, and symptoms managed by emergency physicians. . Covers common conditions, trauma, and nontrauma emergencies. One disease per page with bulleted key points for easy access. Diagnosis, differential, treatment, pearl, and references for each condition. Great for medical students, residents, nurse practitioners, physician's assistants, and general and family practitioners. . UNIQUE EMERGENCY MEDICINE QUICK REFERENCE!. . One-of-a-kind guide to emergency medicine at a glance. Easy-scan, bulleted lists of diagnostics, treatments, and other basics. Pearl per pageA memorable pearl for each disease. Select references--One general review for each disorder. . [starburst] A PEARL PER PAGE!. . Shock Cardiac Emergencies Pulmonary Emergencies Gastrointestinal Emergencies Neurologic Emergencies Genitourinary Emergencies Vascular Emergencies Hematologic Emergencies Infectious Disease Emergencies Metabolic And Endocrine Emergencies Electrolyte And Acid-Base Emergencies Rheumatologic Emergencies Obstetric And Gynecologic Emergencies Eye Emergencies ENT Emergencies Head Trauma Maxillofacial And Neck Trauma Chest Trauma Abdominal Trauma Genitourinary Trauma Vertebral And Spinal Injuries Orthopedic Emergencies Hand Emergencies Dermatologic Emergencies Psychiatric Emergencies Emergencies Due to Physical And Environmental Agents Pediatric Emergencies Nuclear, Biologic, And Chemical Agents of Terrorism. . Visit http: //www.accessmedbooks.com. The best source for medical education And reference. .

The Yearbook compiles the most recent, widespread developments of experimental and clinical research and practice in one comprehensive reference book. The chapters are written by well recognized experts in the field of intensive care and emergency medicine. It is addressed to everyone involved in internal medicine, anesthesia, surgery, pediatrics, intensive care and emergency medicine.

This is the most practical, concise guide to medical practice in extreme and remote environments. With an increase in visits to remote and dangerous locations around the world, the number of serious and fatal injuries and illnesses associated with these expeditions has markedly increased. Medical personnel working in or near such locations are not always explicitly trained in the management of unique environmental injuries, including high-altitude sickness, the bends, lightning strikes, frostbite, acute dehydration, venomous stings and bites, and tropical diseases.
Many health care professionals seek training in the specialty of wilderness medicine to cope with the health risks faced when far removed from professional care resources, and the American College of Emergency Medicine has recently mandated that a minimum level of proficiency needs to be exhibited by all ER physicians in this discipline. This book covers everything a prospective field physician or medical consultant needs to prepare for when beginning an expedition and explains how to treat a variety of conditions in a concise, clinically oriented format.

This is the second edition of the book originally published under the title Medical Emergencies Caused by Aquatic Animals: A Zoological and Clinical Guide. Including updated chapters, new content and additional references, it discusses follow-up with patients, describes diseases that are not emergencies and explains procedures that can take place at health stations and outpatient centers, focusing on clinical and biological aspects relevant to researchers and practitioners alike. The chapter on Invertebrate Aquatic Animals presents facts and advances that were left out of the first edition. In addition, it includes improved images. The subtopic on Cnidaria presents recent data on outbreaks and new species identification in unprecedented areas, with a timely discussion on first aid treatment. The chapter on Injuries by Vertebrate Aquatic Animals has been improved, based on continued work with bathers and fishermen. Featuring numerous images and representative clinical cases, it explores the most significant injuries caused by fish around the globe. The chapter on Ingestion of Aquatic Venomous Animals: Toxinology, Clinical Aspects, and Treatment discusses outbreaks of intoxication diseases from eating fish and seafood, drawing on reliable records of serial cases of Haff's syndrome, scombroidism and ciguatera. Further, it examines the indiscriminate consumption of aquatic animals, which the author argues present the same (or even greater) risks of poisoning and infections as terrestrial animals. Lastly, since there is a general lack of awareness of the risk of infections in aquatic environments, the chapter on Bacterial and Fungal Infections in Aquatic Environments describes the symptoms and treatments and highlights preventive measures.

Delayed recognition of an injury or improper stabilization of the spine can lead to irreversible spinal cord injury and permanent neurological damage. This highly illustrated resource chronicles the rapid developments in imaging technology and expertise over the past decades that have transformed the medical management of vertebral injury, including thoracolumbar trauma classification. With over 250 CT and MRI images, this essential text is designed to aid both trainees and practicing physicians in making rapid and accurate diagnoses to patients with spinal trauma and provide appropriate care. This clear, concise, case-based resource will serve as a guide and learning source for trainees as well as an easily navigable reference for medical practitioners that can be essential to establishing the presence of an acute spinal injury.

An authoritative pocket-sized guide on the medical and surgical management of neurosurgical intensive care patients Decompression is still the mainstay of surgical intervention for neurosurgeons treating neurocritical care patients. However, during the last 20 years, an evolution away from a mechanistic approach has transformed neurocritical care into an increasingly multidisciplinary field. Neurosurgical Intensive Care, 2nd Edition reflects this new paradigm, authored by a neurosurgeon with contributions from experts in the fields of neurology, vascular neurology, interventional neuroradiology, anesthesiology, critical care, traumatology, nutrition, and advanced practice nursing. Neuromonitoring advances have enabled customized interventions tailored to each patient's unique circumstances. The critical care of neurosurgical patients has evolved from an emphasis on pulmonary care (ventilation and oxygenation) to a more nuanced understanding of cerebral protection measures required to manage a disrupted blood-brain-barrier. This edition encompasses advances in the use of ICP monitors, external ventricular devices, brain tissue oxygen monitoring devices, cerebral microdialysis, fluid and electrolyte correction, as well as the increasing use of continuous EEG in the ICU. Key Features Straightforward summaries for each stage of patient care including bedside exams, neuroimaging, lab work, triage procedures, sedation and pain management, neuropharmacology, nutritional needs, administration of fluids, and more. 159 tables and figures facilitate rapid evaluation and decision making. Clinical pearls on a wide range of ICU scenarios - from pathophysiology and management of coma - to interventions for spinal cord injury, multisystem injuries, acute ischemic stroke, and pediatric cases. Insights on how to handle family communication and spiritual needs, medical-legal issues, and discharge planning This compact, highly practical handbook provides a stellar reference for managing critically ill neurosurgical patients in the ICU. It is a must-have resource for nurses, medical students, residents, fellows, and attending physicians who treat these patients.

A common symptom of psychiatric and medical disorders, agitation often appears in a variety of medical environments. This practical guide explores the origins of the condition and the differing approaches and treatments available. The biology of agitation is discussed, followed by specific chapters on substance abuse, medical causes, personality disorders, and treatment in pediatrics and the elderly. Treatment options including psychiatric work-ups, medical work-ups, psychopharmacology, de-escalation, and calming techniques are provided. The complexities of legal issues, patients' rights, and prehospital settings are also addressed, providing physicians, nurses, and mental health workers with a comprehensive resource in providing safe, focused, and effective treatment.

Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. THE INSIDER'S GUIDE TO ACING THE EMERGENCY MEDICINE BOARDS - NOW WITH FULL COLOR PHOTOS! Features: * A thorough and user-friendly review of the most frequently test topics * NEW! Review questions at the end of each chapter to test your knowledge * NEW! Vibrant full-color photographs * Insider tips and study strategies to maximize your study time and improve your performance * Integrated vignette Q&As prepare you for what you will see on exam day * Hundreds of high-yield tables, diagrams, and illustrations

An easily accessible guide to diagnosing and managing critical situations, Emergencies in Gastroenterology and Hepatology aids doctors in dealing with acutely sick patients quickly and effectively. The book provides practical advice on how to make difficult decisions in an emergency situation. Areas covered include life and death emergencies, as well as the broad problems faced by on-call Gastroenterologists and Hepatologists on a daily basis. The focus throughout is on immediate management, but the book also includes reference to long term follow up for certain problems. Each chapter has an associated algorithm, which summarises the contents of the chapter, providing an aide memoir for the reader and facilitating learning, as well as being a quick reference tool. Bullet-point information for speed and clarity combined with the integral cross-referencing system, further enables quick access to the necessary information.