""This is an excellent text which covers all of the important research methods in the field, including randomised control trials. A strong component of the text is the inclusion of chapters on ethics and the future of paramedic research... The use of paramedic examples throughout the chapters will help students and other budding paramedic researchers connect with the subject matter and help them link theory, evidence and practice."
Professor Peter O'Meara, La Trobe Rural Health School, La Trobe University, Australia"

This practical book provides a no nonsense guide for student and qualified paramedics looking to understand the key elements of research, and what it means for their profession. The authors explain key concepts and methodologies to help you get to grips with the nature of paramedic research and how it works in practice.

By drawing on a wealth of cases and examples, research is placed firmly in the context of clinical practice. The book will enable you to critique research and to engage in small-scale research projects of your own. Emphasising what you need to know, the book includes information on: Knowledge that underpins practice Key elements of qualitative and quantitative research Research ethics and evidence based practice Undertaking a literature review Dissemination of research findings Considerations of the future for paramedic research Written by experienced lecturers, the authors offer practical advice and tips to more advanced researchers on getting work published and giving oral and poster presentations at conferences.

"Contributors Jayne Cutter, Gary Rolfe, Megan Rosser, Julia Williams, Malcolm Woollard

Im Jahre 1954 veroeffentlichten SHAW und Mitarbeiter in Australien [147] die Entdeckung einer auffallenden barbituratantagonistischen Wirkung des ss, ss- Methylathylglutarsaureimids. Das ist eine Substanz, die inzwischen auch als NP 13 und unter verschiedenen anderen Namen (Bemegride, Eukraton, Malysol und Megimide) Eingang in die Medizin gefunden hat. Wir verwenden im fol- genden die Bezeichnung Bemegrid. Die Synthese dieses Stoffes, der chemisch auch als 4.4-Methylathyl-2.6-dioxo- piperidin aufgefasst werden kann, war zwar seit langem bekannt (THOLE und THORPE, 1911 [164]), von seinen pharmakologischen Eigenschaften ist jedoch in fruheren Untersuchungen nur eine krampferzeugende Wirkung festgestellt worden (BENICA und WILSON [7]). Um die Rolle besser verstandlich zu machen, die Bemegrid seit der Entdeckung von SHAW und Mitarbeitern in Pharmakologie und Klinik der Schlafmittel- vergiftungen gespielt hat, wollen wir die ersten Ergebnisse der tierexperimentellen und klinischen Untersuchungen in ihren wesentlichen Punkten auffuhren. Die neue Substanz zeigte an Mausen, Ratten, Kaninchen, Katzen und Hunden in tiefer Narkose mit verschiedenen kurz- und langwirkenden Barbituraten (Thiopental, Pentobarbital, Phenobarbital und Barbital) bei enteraler und parente- raler Zufuhr deutliche Narkoseverkurzung und - ausgenommen bei Katzen- auch Weckwirkung. An Kaninchen in toedlicher Thiopentalvergiftung hatte Bemegrid lebens rettende Wirkung. Die Atmung von Katzen und Kaninchen, die unter der Narkose vermindert war, wurde durch Bemegrid wieder gesteigert.

An important addition to the popular Step-Up series, Step-Up to Emergency Medicine uses the proven series format to provide a high-yield review of emergency medicine, ideal for preparing for clerkships/clinical rotations, end of rotation/shelf exams, and the USMLE Step 2. Clinical pearls, full-color illustrations, and "Quick Hits" provide essential information in an efficient, easy-to-remember manner, perfect for medical, physician assistant, and nurse practitioner students. Step-Up to Emergency Medicine delivers exactly what you need to know-both for exam preparation and for practical use in the evaluation and treatment of patients in the emergency department. Succinct, outline approach focuses on the core content you need to know. "Quick Hits" in the margins highlight highly testable topics. Clinical pearls help you identify clinical connections for handy retrieval at test time, and aid in the transition from basic science to clinical medicine. More than 100 full-color photographs and line drawings illustrate key concepts throughout. Easy-to-follow algorithms show examples of effective clinical reasoning, particularly for similar complaints. Numerous charts, tables, graphs, and mnemonics facilitate easy retention of essential material. 100 online questions with complete rationale for correct and incorrect answers, help prepare you for exams and clinical practice. Coverage includes every essential area of emergency medicine, including psychiatric, pediatric, and environmental emergencies; trauma, wounds, toxicology, and medicolegal considerations-as well as must-know information on relevant pathophysiology, clinical features, differential diagnoses, patient evaluation, therapy, and more.