Heavy metals and metalloids, singly or in combination, induce toxic manifestations either through acute or chronic pathology. In particular, long-term chronic exposure to diverse heavy metals and metalloids to humans and animals can lead to numerous physical, muscular, neurological, nephrological, and diverse degenerative diseases and dysfunctions, including multiple sclerosis, muscular dystrophy, Parkinson's and Alzheimer's diseases, cardiovascular disorders, and several others. Recognized heavy metals such as lead, mercury, arsenic, cadmium, thallium, and hexavalent chromium are known for enormous toxicity. The immediate vital signs of acute heavy metal exposure include nausea, vomiting, diarrhea, and acute abdominal pain. Mercury has been identified as the most toxic heavy metal, and mercury poisoning is known as acrodynia or pink disease. Similarly, lead, another toxic heavy metal, was at one time an integral part of painting. Metal Toxicology Handbook further explains and discusses the varying attributes of metals, discussing toxicity, safety, and proper human utilization of metals. Beginning with a broad overview of metals, metalloids, redox biology, and neurodegeneration and going further into the roles, benefits, and toxicity of metals with each section, the text contains 28 chapters from eminent researchers and scientists in their respective fields and is a must-have for anyone researching the potential toxicity in metals. Key Features Discusses the pathology of metal toxicity Highlights the benefits of metals Explains the mechanism and salient features of restoring metabolic homeostasis Highlights dose-dependent beneficial and adverse effects of vanadium safety and toxicity The initial introductory section provides a broad overview of metals, metalloids, redox biology, and neurodegeneration. The second section discusses the pathology of metal toxicity in two chapters, while the third section highlights the mechanism and salient features of restoring metabolic homeostasis in two chapters. The fourth section demonstrates the aspect of radionuclides toxicity. In a change of pace, the fifth section discusses the benefits of metals in four chapters. The sixth section, titled "Toxic Manifestations by Diverse Heavy Metals and Metalloids," provides fourteen chapters that discuss the toxicological mechanism and manifestation of individual metals. The editors have crafted a commentary titled "A Treatise on Metal Toxicity" and summarized a vivid scenario of metal toxicity and its consequences.

This book summarises the development of experimental techniques for determining the impact mechanical properties of fibre reinforced epoxy laminates, and the experimental results obtained for the tensile, compressive and interlaminar shear properties of various epoxy laminates.

Did the Universe have a beginning? Will it have an end? Or has it always been the same, never changing? This is the subject of cosmology; the study of the Universe, and this book provides a perfect introduction to the subject for anyone that is interested in the wonders of our Universe This book provides an accessible overview of the Standard Model of Cosmology, which is explained in six Cosmological Clues, including evidence for the Big Bang and dark matter and dark energy - the keystones of modern cosmology. It takes readers through some of the most exciting questions in cosmology, such as what evidence do we have that the Universe started from the Big Bang? Has dark matter been observed? Will we ever know what dark energy is? Are the multiverses real? And could the Universe be a hologram? This book is an ideal guide for anyone interested in finding out more about our Universe. It will be of interest to those studying cosmology for the first time, including readers without a scientific background, who have an interest in looking up at the stars and wondering where they all came from! Key features: Contains the latest evidence for the Big Bang, dark matter, and dark energy and explores exciting scientific ideas, such as inflation and multiverses Provides a clear explanation of the main theories of how the Universe evolved based on key observations - the Cosmological Clues Gives the reader a concise introduction to the scientific process, using cosmology as the example, and explores why it has been so successful in creating the technologies we have today

Did the Universe have a beginning? Will it have an end? Or has it always been the same, never changing? This is the subject of cosmology; the study of the Universe, and this book provides a perfect introduction to the subject for anyone that is interested in the wonders of our Universe This book provides an accessible overview of the Standard Model of Cosmology, which is explained in six Cosmological Clues, including evidence for the Big Bang and dark matter and dark energy - the keystones of modern cosmology. It takes readers through some of the most exciting questions in cosmology, such as what evidence do we have that the Universe started from the Big Bang? Has dark matter been observed? Will we ever know what dark energy is? Are the multiverses real? And could the Universe be a hologram? This book is an ideal guide for anyone interested in finding out more about our Universe. It will be of interest to those studying cosmology for the first time, including readers without a scientific background, who have an interest in looking up at the stars and wondering where they all came from! Key features: Contains the latest evidence for the Big Bang, dark matter, and dark energy and explores exciting scientific ideas, such as inflation and multiverses Provides a clear explanation of the main theories of how the Universe evolved based on key observations - the Cosmological Clues Gives the reader a concise introduction to the scientific process, using cosmology as the example, and explores why it has been so successful in creating the technologies we have today

Adding one and one makes two, usually. But sometimes things add up to more than the sum of their parts. This observation, now frequently expressed in the maxim "more is different", is one of the characteristic features of complex systems and, in particular, complex networks. Along with their ubiquity in real world systems, the ability of networks to exhibit emergent dynamics, once they reach a certain size, has rendered them highly attractive targets for research. The resulting network hype has made the word "network" one of the most in uential buzzwords seen in almost every corner of science, from physics and biology to economy and social sciences. The theme of "more is different" appears in a different way in the present v- ume, from the viewpoint of what we call "adaptive networks." Adaptive networks uniquely combine dynamics on a network with dynamical adaptive changes of the underlying network topology, and thus they link classes of mechanisms that were previously studied in isolation. Here adding one and one certainly does not make two, but gives rise to a number of new phenomena, including highly robust se- organization of topology and dynamics and other remarkably rich dynamical beh- iors.

Polymer Coatings: Technologies and Applications provides a comprehensive account of the recent developments in polymer coatings encompassing novel methods, techniques, and a broad spectrum of applications. The chapters explore the key aspects of polymer coatings while highlighting fundamental research, different types of polymer coatings, and technology advances. This book also integrates the various aspects of these materials from synthesis to application. Current status, trends, future directions, and opportunities are also discussed. FEATURES Examines the basics to the most recent advances in all areas of polymer coatings Serves as a one-stop reference Discusses polymer-coated nanocrystals and coatings based on nanocomposites Describes morphology, spectroscopic analysis, adhesion, and rheology of polymer coatings Explores conducting, stimuli-responsive, self-healing, hydrophobic and hydrophilic, antifouling, and antibacterial polymer coatings Covers modeling and simulation With contributions from the top international researchers from industry, academia, government, and private research institutions, both new and experienced readers will benefit from this applications-oriented book. Sanjay Mavinkere Rangappa is a research scientist at the Natural Composites Research Group Lab, Academic Enhancement Department, King Mongkut's University of Technology North Bangkok, Thailand. Jyotishkumar Parameswaranpillai is a research professor at the Center of Innovation in Design and Engineering for Manufacturing, King Mongkut's University of Technology North Bangkok, Thailand. Suchart Siengchin is a professor at and president of King Mongkut's University of Technology North Bangkok, Thailand.

Classical Mechanics: A Computational Approach with Examples using Python and Mathematica provides a unique, contemporary introduction to classical mechanics, with a focus on computational methods. In addition to providing clear and thorough coverage of key topics, this textbook includes integrated instructions and treatments of computation. Full of pedagogy, it contains both analytical and computational example problems within the body of each chapter. The example problems teach readers both analytical methods and how to use computer algebra systems and computer programming to solve problems in classical mechanics. End-of-chapter problems allow students to hone their skills in problem solving with and without the use of a computer. The methods presented in this book can then be used by students when solving problems in other fields both within and outside of physics. It is an ideal textbook for undergraduate students in physics, mathematics, and engineering studying classical mechanics. Features: Gives readers the "big picture" of classical mechanics and the importance of computation in the solution of problems in physics Numerous example problems using both analytical and computational methods, as well as explanations as to how and why specific techniques were used Online resources containing specific example codes to help students learn computational methods and write their own algorithms A solutions manual is available via the Routledge Instructor Hub and extra code is available via the Support Material tab

Natural Products Chemistry: Biomedical and Pharmaceutical Phytochemistry focuses on the development of biochemical, biomedical and their applications. It highlights the importance of accomplishing an integration of engineering with biology and medicine to understand and manage the scientific, industrial, and clinical aspects. It also explains both the basic science and the applications of biotechnology-derived pharmaceuticals, with special emphasis on their clinical use. The biological background provided enables readers to comprehend the major problems in biochemical engineering and formulate effective solutions. This title also expands upon current concepts with the latest research and applications, providing both the breadth and depth researchers need. The book also introduces the topic of natural products chemistry with an overview of key concepts. This book is aimed at professionals from industry, academicians engaged in chemical science or natural product chemistry research, and graduate-level students.

Modern Electrosynthetic Methods in Organic Chemistry introduces readers to new ways of making materials and compounds using low waste processes, employing energy from electricity rather than chemical reagents. It explores electro-organic synthesis, which offers clean synthesis tools as well as unusual reaction intermediates and reaction types. Despite applications previously remaining niche, due to the advent of microfluidic reactors this book is a must-read for industry professionals and academics alike. It targets specific areas of recent progress and development in the field that show high novelty and potential, at the same time inviting a wider range of applications in green and clean technology. Key Features: Offers clean synthesis tools Targets areas of recent progress and development Addresses the most recent advances in the field

This 5-volume set allows you to assess the health and environmental effects of chemicals by determining the routes of exposure of the chemical to sensitive organisms. Environmental Fate and Exposure of Organic Chemicals provides relevant facts on how individual chemicals behave in the environment and how humans and environmental organisms are exposed to the chemicals during their production, rise, transport, and disposal. Each chemical is prepared by one of the best-known organizations in environmental fate and exposure and is peer-reviewed by a panel of expert scientists. The information on each chemical includes all experimental values and references for physical properties, all chemical fate studies, and all available monitoring data and interpretative summaries.

Membrane-Distillation in Desalination is an attempt to provide the latest knowledge, state of the art and demystify outstanding issues that delay the deployment of the technology on a large scale. It includes new updates and comprehensive coverage of the fundamentals of membrane distillation technology and explains the energy advantage of membrane distillation for desalination when compared to traditional techniques such as thermal or reverse osmosis. The book includes the latest pilot test results from around the world on membrane distillation desalination.

"This book provides up-to-date knowledge of space debris and valuable insights on how to grapple with this issue from legal, technical, economical and societal aspects. I would strongly recommend that everyone who is working on space development and utilizations and even non-specialists once read this book and think over how human being should be faced with this issue." –Prof. Shinichi Nakasuka, University of Tokyo, Japan Space Debris Peril: Pathways to Opportunities takes readers through the wide spectrum of problems created by space debris – including technical, political, legal and socio-economical aspects – and suggests ways to mitigate its negative consequences and create new opportunities. With chapter contributions from authors at world-renowned universities, private or public entities, and research institutes active in the field of space debris mitigation, space policy and law, risk and resilience, liability and insurance, this book provides a comprehensive introduction to the subject helping the reader to grasp the whole picture of the current space debris remediation challenges. This book will be of interest to the scientific communities, policy makers, business developers, (re)insurers and international standards developers for space operations and orbital debris mitigation. Also, it should appeal to a broader audience among non-specialists in various sectors and the general public. Key features: Brings together interdisciplinary perspectives on the topic in one, cohesive book Chapter contributions from specialists in this interdisciplinary field from around the globe Up-to-date information with the latest developments

This multilingual dictionary explains, in simple and clear language, the most frequently used terms and expressions in the field of nuclear reactor physics and engineering, and provides translations of these terms from English into French, German, Swedish and Polish. This unique resource offers many advantages over the use of online translation tools, which are often incorrect when dealing with scientific and technical words. Instead, this dictionary has used a wide variety of peer-reviewed books and journal papers to ensure the highest accuracy and establish itself as a reliable and credible reference for the reader. It covers a broad range of exciting topics and the latest developments in the field, including reactor technology, reactor components and systems, reactor operation and control, reactor types, reactor physics, thermal engineering, reactor safety, radiation protection, nuclear fuel, nuclear chemistry, the safeguarding of nuclear materials and much more. This dictionary is kept on a technical level corresponding to masters-level and PhD studies of nuclear physics and engineering. It will provide the reader with a broad understanding of the necessary information that a researcher or nuclear physicist or engineer would need to possess; therefore, it will be an invaluable resource for students within these and related disciplines. Features: Contains over 1500 key terms from the field The first book to provide translations in five languages: English, French, German, Swedish and Polish Accessible to masters-level and PhD students in addition to early career researchers in nuclear reactor physics and engineering

Synthetic Sorbent Materials Based on Metal Sulphides and Oxides focuses on development of inorganic nanomaterials for removal of metallic species from the aqueous environment. General synthetic methods to prepare such materials are lacking. This book investigates problems of controlled synthesis of these materials and the effect of their morphological characteristics on their sorption capacity. * Synthesizes experimental data on the synthesis of micro- and nanoparticles of zinc, copper, and cadmium sulfides, iron oxides, and manganese oxyhydroxide. * Discusses controlled synthesis of zinc, cadmium, and copper sulfide particles and their sorption properties. * Describes production of iron oxides (hematite and magnetite) and manganese oxyhydroxide particles. * Features numerous SEM images of the obtained nanostructures and original graphs of various characteristics. * Offers practical recommendations. This book is of interest to researchers and scientists working with inorganic synthesis and properties of sorption materials.

21st Century Nanoscience - A Handbook: Public Policy, Education, and Global Trends (Volume 10) will be the most comprehensive, up-to-date large reference work for the field of nanoscience. Its predecessor, Handbook of Nanophysics, by the same editor was published in the fall of 2010 and was embraced as the first comprehensive reference to consider both fundamental and applied aspects of nanophysics. This follow-up project has been conceived as a necessary expansion and full update that considers the significant advances made in the field since 2010. It goes well beyond the physics as warranted by recent developments in the field. This tenth volume in a ten-volume set covers nanophotonics, nanoelectronics, and nanoplasmonics. Key Features: Provides the most comprehensive, up-to-date large reference work for the field. Chapters written by international experts in the field. Emphasizes presentation and real results and applications. This handbook distinguishes itself from other works by its breadth of coverage, readability and timely topics. The intended readership is very broad, from students and instructors to engineers, physicists, chemists, biologists, biomedical researchers, industry professionals, governmental scientists, and others whose work is impacted by nanotechnology. It will be an indispensable resource in academic, government, and industry libraries worldwide. The fields impacted by nanophysics extend from materials science and engineering to biotechnology, biomedical engineering, medicine, electrical engineering, pharmaceutical science, computer technology, aerospace engineering, mechanical engineering, food science, and beyond.

Comprises four parts, the first of which provides an overview of the topics that are developed from fundamental principles to more advanced levels in the other parts. Presents in the second part an in-depth introduction to the relevant background in molecular and cellular biology and in physical chemistry, which should be particularly useful for students without a formal background in these subjects. Provides in the third part a detailed treatment of microscopy techniques and optics, again starting from basic principles. Introduces in the fourth part modern statistical approaches to the determination of parameters of interest from microscopy data, in particular data generated by single molecule microscopy experiments. Uses two topics related to protein trafficking (transferrin trafficking and FcRn-mediated antibody trafficking) throughout the text to motivate and illustrate microscopy techniques

Students are naturally drawn to quantum science by the intriguing behaviors of small particles. However, they can also be intimidated by the lengthy and complicated treatment found in the classroom. Understanding Quantum Science: A Concise Primer for Students of Chemistry, Biochemistry, and Physics is a highly accessible book that offers students an opportunity to grasp the most fascinating of quantum topics, without the intimidation. To be sure, math is necessary, but it is introduced as needed and kept concise. The emphasis is on the science: a certain differential equation can be solved, and when it is, we find the energies that hydrogen atom electrons are allowed to have. Each concept is developed in this manner, keeping focus on how and why it arises, and on the intriguing consequences. This book provides a brief tour of some of the wonders of quantum science. But it is more than that, it is designed to be the most concise tour possible that truly explains how these wonders arise so that you can develop a working understanding of quantum concepts. If your goal is loftier and you wish to become a quantum specialist, the conceptual groundwork presented here, along with rationalization of the mathematics required, will position you well for higher level classes.

Volume 2: Physical Properties of Nanostructured Materials and Their Applications of Nanotechnology: The Physics of Nanomaterials (2-volume set) provides a good overview of the main techniques of the working principles and the type of structures that can be produced with nanomaterials. Specifically, Volume 2 discusses the mechanical, electrical, and optical properties of nanostructures as well as nanomagnetism, spintronics, spin dynamics, as well as a broad range of applications to illustrate how the physical properties of materials can be manipulated to perform very specific functions. Nanotechnology: The Physics of Nanomaterials (2-volume set) is a comprehensive guide to the various aspects of nanophysics. The author's microscopic approach illustrates how physical principles can be used to understand the basic properties and functioning of low-dimensional systems. It provides an in-depth introduction to the techniques of production and analysis of materials at the nanoscopic level. Much of physics is based on our understanding of solid-state physics. These volumes show how limitations of size can give rise to new physical properties and quantum effects, which can be exploited in new applications and devices. Volume 1: The Physics of Surfaces and Nanofabrication Techniques provides a broad introduction to nanophysics and nanotechnologies, and the importance of low-dimensional and surface physics is discussed indepth. Chapters in Volume 1 covers the large range of physical preparation techniques available for the production of nanomaterials and nanostructuring. Key features: Provides a comprehensive treatment of nanoscience, covering all major areas of the physics involved in nanostructures, including sample preparation techniques, characterization methods, physical principles, and applications Presents an introduction and summary to each chapter, highlighting the principal ideas of each chapter in a concise manner Includes revision problems that will allow students to assess their progress at the end of each chapter Incorporates the author's 25 years research experience Based on a lecture course the author has given over a period of several years, Nanotechnology: The Physics of Nanomaterials includes the benefit of feedback from students, helping to make the subject matter approachable and appealing to newcomers and students. The volumes will be valuable for courses in nanotechnologies, nanomedicine, nanobiotechnologies and more.

The book fills a void as a textbook with hands-on laboratory exercises designed for biomedical engineering undergraduates in their senior year or the first year of graduate studies specializing in electrical aspects of bioinstrumentation. Each laboratory exercise concentrates on measuring a biophysical or biomedical entity, such as force, blood pressure, temperature, heart rate, respiratory rate, etc., and guides students though all the way from sensor level to data acquisition and analysis on the computer. The book distinguishes itself from others by providing electrical circuits and other measurement setups that have been tested by the authors while teaching undergraduate classes at their home institute over many years. Key Features: * Hands-on laboratory exercises on measurements of biophysical and biomedical variables * Each laboratory exercise is complete by itself and they can be covered in any sequence desired by the instructor during the semester * Electronic equipment and supplies required are typical for biomedical engineering departments * Data collected by undergraduate students and data analysis results are provided as samples * Additional information and references are included for preparing a report or further reading at the end of each chapter Students using this book are expected to have basic knowledge of electrical circuits and troubleshooting. Practical information on circuit components, basic laboratory equipment, and circuit troubleshooting is also provided in the first chapter of the book.

This book is dedicated to the fundamental physical aspects of stability, the influence of structural defects on the properties and structural phase transformations of BCC alloys. The authors present patterns that occur in the structural-phase states of functional alloys with low stability or instability under thermal cycling effects. Structural-phase transformations and the physical laws governing the influence of the thermomechanical effect on the properties of alloys are examined to advance development of technological processes for processing functional materials. Features: Studies the correlation between structural phase states and changes in the physico-mechanical properties of intermetallic compounds Explores the influence of thermomechanical cycling on the properties of functional alloys Details low-stability pretransition states in alloys

Archimedes to Hawking takes the reader on a journey across the centuries as it explores the eponymous physical laws-from Archimedes' Law of Buoyancy and Kepler's Laws of Planetary Motion to Heisenberg's Uncertainty Principle and Hubble's Law of Cosmic Expansion-whose ramifications have profoundly altered our everyday lives and our understanding of the universe. Throughout this fascinating book, Clifford Pickover invites us to share in the amazing adventures of brilliant, quirky, and passionate people after whom these laws are named. These lawgivers turn out to be a fascinating, diverse, and sometimes eccentric group of people. Many were extremely versatile polymaths-human dynamos with a seemingly infinite supply of curiosity and energy and who worked in many different areas in science. Others had non-conventional educations and displayed their unusual talents from an early age. Some experienced resistance to their ideas, causing significant personal anguish. Pickover examines more than 40 great laws, providing brief and cogent introductions to the science behind the laws as well as engaging biographies of such scientists as Newton, Faraday, Ohm, Curie, and Planck. Throughout, he includes fascinating, little-known tidbits relating to the law or lawgiver, and he provides cross-references to other laws or equations mentioned in the book. For several entries, he includes simple numerical examples and solved problems so that readers can have a hands-on understanding of the application of the law. A sweeping survey of scientific discovery as well as an intriguing portrait gallery of some of the greatest minds in history, this superb volume will engage everyone interested in science and the physical world or in the dazzling creativity of these brilliant thinkers.

Ultrasonic Welding of Metal Sheets covers various aspects of ultrasonic welding (USW) of metal sheets, including the discussion on modeling and numerical simulations of ultrasonic welding to improve this welding process and performance. This book aims to provide an accessible, comprehensive and up-to-date exposition of the various aspects of joining of dissimilar metal sheets ranging from its fundamentals thorough to metallurgical characteristics covering fundamental concepts, in-detailed explanation about the USW including its implementation, design criteria, work material, welding, thermo-mechanical and research scopes. The book is aimed at researchers, professionals and graduate students in manufacturing, welding, mechanical engineering. Features The ultrasonic spot welding of various metal sheets is described in simplified expression and concepts are elucidated by relevant illustrations. Discusses modeling and numerical simulations of ultrasonic welding to improve the ultrasonic welding process and performance As opposed to competition in the market, this title provides thorough clarification of ultrasonic spot welding of metal sheets with its applications.

This volume provides an updated collection of protocols for manipulating and studying VEGF signaling pathways in vitro and in vivo and aims to present a range of both firmly established and newly emerging technologies. Covering multiple model species, from mouse to zebrafish to human, the book explores the role of VEGF and VEGFR isoforms in exosomes, cultured cells, or in tissues, as well as robust cell assays for the investigation of basic angiogenic mechanisms and VEGF signaling in more complex cellular systems, amongst other subjects. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, VEGF Signaling: Methods and Protocols, Second Edition provides a useful tool for researchers in the vascular biology community and beyond in understanding the basic biology of VEGF signaling and in translating this research into the clinic.

For over forty years, Materials for Engineers and Technicians has given thousands of students an easily accessible introduction to materials engineering and manufacturing processes. This renowned text is a comprehensive overview of the wide-ranging subject area, written in a straightforward, readable style. It is devoid of excessive jargon and mathematical complexity, and retains a practical down-to-earth approach. This expanded edition references specifications for materials and materials testing that have been updated to include European-wide standards of the EU. More applications of materials and case studies have been included. New content discusses the choice of materials and processes in relation to 3D printing and the importance of materials recycling and sustainability. The increased emphasis on the selection of materials reflects this aspect of materials engineering now seen within current vocational and university courses. In addition to meeting the requirements of vocational and undergraduate engineering syllabuses, this text also serves as a valuable desktop reference for professional engineers working in product design who require a quick source of information on materials and manufacturing processes.

Surface Structure Modification and Hardening of Al-SI Alloys explores the hardening of material surfaces using concentrated energy flows resulting in the nanostructuring of surface layers. The authors demonstrate how these methods achieve a reduction in plastic deformation of the surface and a more uniform distribution of elastic stresses near the surface during operational use, significantly reducing part failure. It presents results from research and scientific and technological enterprises involved with the modification of light alloy surfaces for use in the automobile and aerospace industries. Additional key features include: Addresses theoretical and experimental research computer simulations of structural phase transformations at the nanolevel to create new materials Details and compares electroexplosion alloying, electron beam processing and electron-plasma alloying of an Al-Si Alloy Explains multiphase plasma jet treatment to obtain high-quality coatings with good and high functional properties This reference is a valuable resource for specialists in the field of physical material science, condensed state physics, metal science and thermal treatment and will be of interest to undergraduate and post-graduate students in these fields.