Modern adhesive dentistry has numerous applications in cariology, as well as in aesthetic and pediatric dentistry, prosthodontics, implantology, and orthodontics-in essence, in comprehensive dental care. This unique book addresses various ramifications of adhesion and adhesives in the broad domain of dentistry. The topics covered include testing aspects of dental materials, dentin bonding, restorations, and adhesion promotion. This book reflects the cumulative wisdom of many world-renowned researchers and provides a useful reference to anyone involved in the various aspects of dentistry.

Tissue Engineering Strategies for Organ Regeneration addresses the existing and future trends of tissue engineering approaches for organ/tissue regeneration or repair. This book provides a comprehensive summary of the recent improvement of biomaterials used in scaffold-based tissue engineering, and the tools and different protocols needed to design tissues and organs. The chapters in this book provide the in-depth principles for many of the supporting and enabling technologies including the applications of BioMEMS devices in tissue engineering, and the combination of organoid formation and three dimensional (3D) bioprinting. The book also highlights the advances and strategies for regeneration of three-dimensional microtissues in microcapsules, tissue reconstruction techniques, and injectable composite scaffolds for bone tissue repair and augmentation. Key Features: Addresses the current obstacles to tissue engineering applications Provides the latest improvements in the field of integrated biomaterials and fabrication techniques for scaffold-based tissue engineering Shows the influence of microenvironment towards cell-biomaterials interactions Highlights significant and recent improvements of tissue engineering applications for the artificial organ and tissue generation Describes the applications of microelectronic devices in tissue engineering Describes different current bioprinting technologies

Design of new processes that avoid the use of toxic reagents has been the focus of intense research of late. Catalysis by metals and non-metals offers diverse opportunities for the development of new organic reactions with promising range of selectivities-chemoselectivity, regioselectivity, diastereoselectivity, and enantioselectivity. Furthermore, these transformations frequently occur under mild conditions, tolerate a broad array of functional groups, and proceed with high stereoselectivity. The area of catalysis is sometimes referred to as a 'foundational pillar' of green chemistry. Catalytic reactions often reduce energy requirements and decrease separations because of increased selectivity; they are also capable of permitting the use of renewable feedstocks of less toxic reagents or minimizing the quantities of reagents needed. New catalytic organic synthesis methodologies have, thus, offered several possibilities for considerable improvement in the eco-compatibility of fine chemical production. Hence, these catalytic methodologies have emerged as powerful tools for the efficient and chemoselective synthesis of heterocyclic molecules. Key Features: Presents the synthesis of different five-membered heterocycles. Contains the most up-to-date information in this fast-moving field. Covers novel catalytic approaches used in the study and application of catalysts in synthetic organic reactions. Presents new methodologies for the synthesis of heterocycles.

Blood microcirculation is essential to our bodies for the successful supply of nutrients, waste removal, oxygen delivery, homeostasis, controlling temperature, wound healing, and active immune surveillance. This book provides a physical introduction to the subject and explores how researchers can successfully describe, understand, and predict behaviours of blood flow and blood cells that are directly linked to these important physiological functions. Using practical examples, this book explains how the key concepts of physics are related to blood microcirculation and underlie the dynamic behavior of red blood cells, leukocytes, and platelets. This interdisciplinary book will be a valuable reference for researchers and graduate students in biomechanics, fluid mechanics, biomedical engineering, biological physics, and medicine. Features: The first book to provide a physical perspective of blood microcirculation Draws attention to the potential of this physical approach for novel applications in medicine Edited by specialists in this field, with chapter contributions from subject area specialists

A contribution to the series on Natural Products Chemistry of Global Plants, Natural Products Chemistry of Botanical Medicines from Cameroon focuses on the sources and chemistry of natural products from plants in Cameroon, West Africa. The plants selected offer an opportunity to trace a route through history from ancient civilizations to the modern day, showing the important value to man of natural products in medicines and in foods. This book highlights how many of the extracts from Cameroon are today associated with important drugs, nutrition products, beverages, perfumes, cosmetics and pigments, as well as presenting their complex chemistry and structure. Key Features: Forms an important part of the series on Natural Products Chemistry of Global Plants, as Cameroon is a country with rich experience in the use of medicinal plants and with a wide diversity of botanical resources Addresses the current development of pharmacognosy research in Cameroon Provides readers with updated information on the chemistry and pharmacology of natural products with pharmaceutical potential Covers an extensive range of chemical, botanical and pharmacological diversities Xavier Siwe Noundou is a Scholar/Scientist based at Rhodes University in Grahamstown, South Africa. He has been a EU FP7 Marie Curie Fellow (2015-2016), Kaposvar University in Hungary (2015, 2016), Trakia Univesity in Bulgaria (2016), TWAS Fellow (2013), National Research Foundation South Africa Fellow (2014-2016). Dr Noundou works on Medicinal Chemistry focusing on Chemistry, Pharmacognosy and Nanotechnology. His main research interests include terrestrial natural products chemistry (from Cameroon and South Africa) and marine natural products chemistry (from the South African coastline): bioactive metabolites isolated as potential antiparasitic, antimicrobial, antiviral and antiproliferative candidates. He is author of more than forty scientific publications in his field of expertise.

A contribution to the series on Natural Products Chemistry of Global Plants, Natural Products Chemistry of Botanical Medicines from Cameroon focuses on the sources and chemistry of natural products from plants in Cameroon, West Africa. The plants selected offer an opportunity to trace a route through history from ancient civilizations to the modern day, showing the important value to man of natural products in medicines and in foods. This book highlights how many of the extracts from Cameroon are today associated with important drugs, nutrition products, beverages, perfumes, cosmetics and pigments, as well as presenting their complex chemistry and structure. Key Features: Forms an important part of the series on Natural Products Chemistry of Global Plants, as Cameroon is a country with rich experience in the use of medicinal plants and with a wide diversity of botanical resources Addresses the current development of pharmacognosy research in Cameroon Provides readers with updated information on the chemistry and pharmacology of natural products with pharmaceutical potential Covers an extensive range of chemical, botanical and pharmacological diversities Xavier Siwe Noundou is a Scholar/Scientist based at Rhodes University in Grahamstown, South Africa. He has been a EU FP7 Marie Curie Fellow (2015-2016), Kaposvar University in Hungary (2015, 2016), Trakia Univesity in Bulgaria (2016), TWAS Fellow (2013), National Research Foundation South Africa Fellow (2014-2016). Dr Noundou works on Medicinal Chemistry focusing on Chemistry, Pharmacognosy and Nanotechnology. His main research interests include terrestrial natural products chemistry (from Cameroon and South Africa) and marine natural products chemistry (from the South African coastline): bioactive metabolites isolated as potential antiparasitic, antimicrobial, antiviral and antiproliferative candidates. He is author of more than forty scientific publications in his field of expertise.

Following recent developments in hypofractionated stereotactic radiation therapy (SRT) for brain and spine tumors, this new edition offers a fully updated and comprehensive "how-to" guidance on hypofractionated SRT for brain and spine metastases, glioma, benign tumors, and other tumor types. Presenting the state of the art of the technology and practice, this book: * Discusses the pros and cons of hypofractionated SRT compared to single-fraction radiosurgery, providing a deeper understanding of radiosurgery and radiobiology * Explains the toxicity and adverse effects of hypofractionated SRT including the dosage of 24 Gy in two spine SBRT fractionation schemes, aiding practitioners in communicating the risks and benefits of treatment and in obtaining consent from their patients * Outlines the current standards for safe practice, including checklists for implementation * Explores new technologies for brain and spine tumors including LITT, MR-guided focused ultrasound, and Zap technology, with chapters authored by well-recognized experts in the radiation, oncology, and neurosurgery communities; this book delivers a level of technological and clinical detail not available in journal papers This book is suitable for radiation oncologists, neurosurgeons, and medical physicists who specialize in brain and/or spine radiosurgery or want to start a program and need a comprehensive reference with key checklists for practice.

Includes over 250 solved problems to supplement graduate-level courses in fluid mechanics and turbomachinery. Enables students to practice applying key concepts of fluid mechanics and the governing conservation laws to solve real-world problems. Uses the physics-first approach, allowing for a good understanding of the problem physics and the results obtained. Covers problems on flowpath aerodynamics design. Covers problems on secondary air systems modeling of gas turbines.

This book focuses on performing hands-on meta-analysis using MetaXL, a free add-on to MS Excel. The illustrative examples are taken mainly from medical and health sciences studies, but the generic methods can be used to perform meta-analysis on data from any other discipline. The book adopts a step-by-step approach to perform meta-analyses and interpret the results. Stata codes for meta-analyses are also provided. All popularly used meta-analytic methods and models - such as the fixed effect model, random effects model, inverse variance heterogeneity model, and quality effect model - are used to find the confidence interval for the effect size measure of independent primary studies and the pooled study. In addition to the commonly used meta-analytic methods for various effect size measures, the book includes special topics such as meta-regression, dose-response meta-analysis, and publication bias. The main attraction for readers is the book's simplicity and straightforwardness in conducting actual meta-analysis using MetaXL. Researchers would easily find everything on meta-analysis of any particular effect size in one specific chapter once they could determine the underlying effect measure. Readers will be able to see the results under different models and also will be able to select the correct model to obtain accurate results.

The Basics of Investigating Forensic Science: A Laboratory Manual, Second Edition presents foundational concepts in forensic science through hands-on laboratory techniques and engaging exercises. The text offers numerous lab projects on a range of subjects including fingerprinting, shoeprint analysis, firearms, pathology, anthropology, forensic biology and DNA, drugs, trace evidence analysis, and more. This Second Edition is fully updated to include extensive full-color photos and diagrams to reflect current best-practices focussing on laboratory procedure, techniques, and interpretation of results. Each laboratory illustrates processes and concepts, and how the equipment should be set up for a given exercise. Many of the exercises can be done with minimal laboratory equipment and material while certain exercises also have additional options and advanced lab exercises-for those education institutions with access to more specialized or advance laboratory equipment. While the sequencing of laboratory exercises in the book is designed to follow The Basics textbook, the lab exercises are intentionally modular can be performed in any sequence desired by an instructor. The Basics of Investigating Forensic Science, Second Edition is an excellent resource for introduction to forensic sciences courses, including the companion textbook it was designed to accompany, Forensic Science: The Basics, Fourth Edition (ISBN: 9780367251499). The book can be used alongside any textbook, and even serve as a stand-alone text for two- and four-year college programs, as well as course at the high school level.

Biological materials and their applications have drawn increasing attention among scientists. Cellulose is an abundant, renewable, biodegradable, economical, thermally stable, and light material, and it has found application in pharmaceuticals, coatings, food, textiles, laminates, sensors, actuators, flexible electronics, and flexible displays. Its nano form has extraordinary surface properties, such as higher surface area than cellulose; hence, nanocellulose can be used as a substitute for cellulose. Among many other sustainable, functional nanomaterials, nanocellulose is attracting growing interest in environmental remediation technologies because of its many unique properties and functionalities. Nanocellulose and Its Composites for Water Treatment Applications supplies insight into the application of nanocellulose and its nanocomposites for water purification and remediation. It covers different classes of nanocellulose-cellulose nanocrystal (CNC), microfibrillated cellulose (MFC), hairy cellulose nanocrystalloid (HCNC), and bacterial nanocellulose (BNC)-for their competency with other renewable and carbonaceous materials such as pectin, alginate, and CNTs. Future perspectives of nanocellulose and nanocomposites gleaned from different biodegradable origins are also discussed. This book delves into an updated description of the basic principles and developments in synthesis, characterization methods, properties (chemical, thermal, optical, structural, surface, and mechanical structure), property relationships, crystallization behavior, and degradability of biodegradable nanocomposites. The book also supplies vivid information about various cellulose nanomaterials and their applications in absorbing organic and inorganic toxins, membrane filtration of bacteria, viruses, and ionic impurities, photocatalytic dye removal, and sensing of water toxins. Features Details the synthesis and characterization methods of nanocellulose Illustrates the applications of nanocellulose and its nanocomposites Shows in-depth accounts of the various types of properties of nanocellulose and its composites Features emerging trends in the use of nanocellulose as adsorbents, sensors, membranes, and photocatalysis materials This book will be useful for academics, researchers, and engineers working in water treatment and purification.

This edited reflects the current state of knowledge about the role of microRNAs in the formation and progression of solid tumours. The main focus lies on computational methods and applications, together with cutting edge experimental techniques that are used to approach all aspects of microRNA regulation in cancer. We are sure that the emergence of high-throughput quantitative techniques will make this integrative approach absolutely necessary in the near future. This book will be a resource for researchers starting out with cancer microRNA research, but is also intended for the experienced researcher who wants to incorporate concepts and tools from systems biology and bioinformatics into his work. Bioinformaticians and modellers are provided with a general perspective on microRNA biology in cancer, and the state-of-the-art in computational microRNA biology.

Polymer-based smart materials have become attractive in recent years due to the fact that polymers are flexible and provide many advantages compared to inorganic smart materials: they are low cost, they are easy to process, and they exhibit good performance at nano- and microscale levels. This volume focuses on a different class of polymers that are used as smart materials in the areas of biotechnology, medicine, and engineering. The volume aims to answer these questions: How do we distinguish 'smart materials'? and How do they work? The chapters lay the groundwork for assimilation and exploitation of this technological advancement. Four of the key aspects of the approach that the authors have developed throughout this book are highlighted, namely the multidisciplinary exchange of knowledge, exploration of the relationships between multiple scales and their different behaviors, understanding that material properties are dictated at the smallest scale, and, therefore, the recognition that macroscale behavior can be controlled by nanoscale design.

This title includes a number of Open Access chapters. This book presents a range of research on important topics in the field. Of the approximately 11 million known chemical compounds, about 10 million are organic. Organic chemists are currently working to produce better polymers with specific properties, such as biodegradable plastics. The understanding of new drug structures from plants and the synthesis of improved pharmaceuticals is another area of great interest. Organic chemists are also researching the reactions that occur in living systems and understanding the molecular causes of disease.

This volume, Engineering Technology and Industrial Chemistry with Applications, brings together innovative research, new concepts, and novel developments in the application of new tools for chemical and materials engineers. It provides a collection of innovative chapters on new scientific and industrial research from chemists and chemical engineers at several prestigious institutions. It looks at recent significant research and reports on new methodologies and important applications in the fields of chemical engineering as well as provides coverage of chemical databases, bringing together theory and practical applications. Highlighting theoretical foundations, real-world cases, and future directions, this authoritative reference source will be a valuable addition for researchers, practitioners, professionals, and students of chemistry material and chemical engineering.

This new volume presents a plethora of new research on the use of nanoconjugate nanocarriers in drug delivery. Nanotechnology as drug carriers has been observed to increase the level of sophistication through a variety of ways. It helps to alleviate some of the pitfalls of conventional dosage forms, such as few pitfalls such as non-specific drug delivery, dose dumping, poor patient compliance, toxicities linked with higher doses, etc. With chapters from highly skilled, experienced, and renowned scientists and researchers, Nanoconjugate Nanocarriers for Drug Delivery is divided into four sections, providing an introduction to nanocarriers for drug delivery, physicochemical features of nanocarriers, and specific applications dealing with drug delivery in particular. The materials used as well as formulation and characterization have been discussed in detail. The nanocarriers covered in the book include nanoparticles, vesicular carriers, carriers having carbon as the core constituent, dispersed systems, etc. The book also delves into the interaction and associations between drug delivery research and its therapeutic applications in practice. The book integrates a wide variety of case studies, research, and theories in an attempt to reveal the diversity and capture the novel approaches of nanoconjugate nanocarriers for drug delivery employed by developers and content experts in the field. This timely publication will be an essential reference and current awareness source, building on the available literature in the field of pharmacy and biomedical science, while also providing ideas for further research opportunities in this dynamic field.

This valuable book is devoted to problems of the synthesis, vulcanization, modification, and study of structure and properties of highly filled sealants based on polysulfide oligomers (PSO). The book summarizes information concerning chemistry, synthesis technology, structure, and properties of liquid thiokols and thiokol-containing polyesters. It also presents a literary survey on chemism and mechanisms for liquid thiokols vulcanization involving oxidants or through polyaddition. The book describes formulation principles of sealants, their properties, and application areas. The book provides research on vulcanization and modification of thiokol sealants involving thiokol-epoxy resin copolymers, unsaturated polyesters, and various isocyanate prepolymers. It describes studies of mechanisms underlying vulcanization of polysulphide oligomers by manganese dioxide, sodium dichromate and zinc oxide, and also of the structure and properties of sealants on the basis of a liquid thiokol and commercial " -2" polymer depending on a chemical nature and the ratio of constituent oligomers. The book gives information on the influence of filling materials on vulcanization kinetics, rheological, and physico-mechanical properties of sealants depending on the nature of PSO. The book will be of interest to research personnel of scientific institutes and centers developing reactive oligomers and their compositions and studying their structure and properties as well as engineers working in science centers or enterprises working in the area of development, production, and application of polysulfide oligomers and sealants.

This important volume highlights the latest developments and trends in chemistry, biochemistry, and biology. It presents the developments of advanced materials and respective tools to characterize and predict the material properties and behavior. The book provides original, theoretical, and important experimental results that use non-routine methodologies often unfamiliar to the usual readers. The papers on novel applications of more familiar experimental techniques and analyses of chemical, biochemistry, and biological programs indicate the need for new experimental approaches.

This informative volume discusses recent advancements in the research and development in synthesis, characterization, processing, morphology, structure, and properties of advanced polymeric materials. With contributions from leading international researchers and professors in academic, government and industrial institutions, Advanced Polymeric Materials for Sustainability and Innovations has a special focus on eco-friendly polymers, polymer composites, nanocomposites, and blends and materials for traditional and renewable energy. In this book the relationship between processing-morphology-property applications of polymeric materials is well established. Recent advances in the synthesis of new functional monomers has shown strong potential in generating better property polymers from renewable resources. Fundamental advances in the field of nanocomposite blends and nanostructured polymeric materials in automotive, civil, biomedical and packaging/coating applications are the highlights of this book.

Nanostructured materials are emerging as a new class of materials that exhibit unique microstructures and enhanced mechanical performance. As an outcome of this, these materials have attracted considerable attention in scientific communities all over the world. There is continuous research to facilitate product development, thereby improving product quality and reliability in industry. This volume is devoted to novel architectures at the nano-level with an emphasis on new synthesis and characterization methods. Special emphasis is given to new applications of nanostructures and nanocomposites in various fields, such as nano-electronics, energy conversion, catalysis, drug delivery and nano-medicine. The chapters are divided into sections focusing on: Nanoparticles Assembly and Nanostructured Materials Nanocomposites Properties Nanostructured Materials for Biomedical Applications

This new volume focuses on different aspects of composite systems that are associated with research and development, helping to bridge the gap between classical analysis and modern real-life applications. The chapters look at the experimental and theoretical aspects of composite materials, regarding preparation, processing, design, properties, and practical implications. It also presents recent advancements, research, and development prospects of advanced composite materials that provide new solutions for advanced technologies.

A collection of highly selected, peer-reviewed chapters, this book showcases the research of an international roster of scientists. It covers nanomaterials with emphasis on synthesis, characterization, and applications. It also presents emerging developments in nanotechnology in areas as diverse as medicine, energy, electronics, and agriculture. In addition to engineering aspects, the book discusses the physics, chemistry and biotechnology behind the fabrication and device designing.

This important book presents a valuable collection of new research and new trends in nanomaterials, mesoscopy, quantum chemistry, and chemical physics processes. It highlights the development of nanomaterials as well as investigation of combustion and explosion processes. It highlights new trends in processes and methods of the treatment of polymeric materials and also covers material modification, including super small quantities of metal/carbon nanocomposites as well as new information on the modeling of processes and quantum calculations. Nonlinear kinetic appearances and their applications are highlighted as well.

This important book presents a collection of scientific papers on recent theoretical and practical advances in nanostructures, nanomaterials, and nanotechnologies. Highlighting some of the latest developments and trends in the field, the volume presents the developments of advanced nanostructured materials and the respective tools to characterize and predict their properties and behavior.

One of the major areas of emphasis in the field of in chemical science and engineering technology in recent years has been interdisciplinary research, a trend that promises new insights and innovations rooted in cross-disciplinary collaboration. This volume is designed for stepping beyond traditional disciplinary boundaries and applying knowledge and insights from multiple fields. This book, Chemical Science and Engineering Technology: Perspectives on Interdisciplinary Research, provides a selection of chapters on interdisciplinary research in chemical science and engineering technology, taking a conceptual, and practical approach. The book includes case studies and supporting technologies and also explains the conceptual thinking behind current uses and potential uses not yet implemented. International experts with countless years of experience lend this volume credibility.