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Investigating Human Diseases with the Microbiome - Metagenomics Bench to Bedside (Paperback)
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Investigating Human Diseases with the Microbiome - Metagenomics Bench to Bedside (Paperback)
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Investigating Human Diseases with the Microbiome: Metagenomics
Bench to Bedside is a summary of underlying principles for human
health and disease studies from a microbiome point-of-view. From
birth to old age, microbiomes in fecal, oral/nasal, vaginal, and
skin samples contain important information that can predict disease
risks in the future. Tissue samples also contain microbes that are
relevant for diseases. The microbiome connects genetic and
environmental factors and is poised to greatly facilitate precision
medicine, including prevention, diagnosis and effective treatment
of many complex diseases. Based in traditional microbiology and
adding a more wholistic view of the advent of high-throughput
sequencing, this reference poses the key questions of the total
number of microbial cells and their distribution in the human body
while also considering concepts from macroecology and from causal
reasoning. An entire chapter is dedicated to methods, providing
hands-on information for important considerations when collecting
samples for metagenomic studies.
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