This updated edition addresses the examined units of the CCEA AS level Life and Health Sciences specification (including the recently-proposed revisions). It covers both the Single and Double Award courses, through the study of the following units: * AS 2: Human Body Systems * AS 3: Aspects of Physical Chemistry in Industrial Processes * AS 5: Material Science The full-colour, illustrated chapters clearly explain the theory for the course, and are supported by worked examples, tips, examination-style questions and answers. The authors are all experienced science teachers and examiners and the book has been through a meticulous quality assurance process prior to publication. Contents: Unit AS 2: Human Body Systems 1 Cardiovascular System 2 Respiratory System 3 Respiration 4 Homeostatic Mechanisms and How These Are Monitored 5 Nutrition and Physical Exercise in Maintaining Good Health Unit AS 3: Aspects of Physical Chemistry in Industrial Processes 6 Chemical Calculations 7 Volumetric Analysis 8 Energetics 9 Kinetics 10 Equilibrium 11 Industrial Processes, Infrastructure and Environmental Consequences Unit AS 5: Material Science 12 Material Properties 13 Categorising Materials and Microscopic Structure 14 Alloys, Metal Working and Biomaterials 15 Smart Materials, Nanomaterials and Industrial Considerations 16 Semiconductors Answers

Peter Hunter Computational physiology for the cardiovascular system is entering a new and exciting phase of clinical application. Biophysically based models of the human heart and circulation, based on patient-specific anatomy but also informed by po- lation atlases and incorporating a great deal of mechanistic understanding at the cell, tissue, and organ levels, offer the prospect of evidence-based diagnosis and treatment of cardiovascular disease. The clinical value of patient-specific modeling is well illustrated in application areas where model-based interpretation of clinical images allows a more precise analysis of disease processes than can otherwise be achieved. For example, Chap. 6 in this volume, by Speelman et al. , deals with the very difficult problem of trying to predict whether and when an abdominal aortic aneurysm might burst. This requires automated segmentation of the vascular geometry from magnetic re- nance images and finite element analysis of wall stress using large deformation elasticity theory applied to the geometric model created from the segmentation. The time-varying normal and shear stress acting on the arterial wall is estimated from the arterial pressure and flow distributions. Thrombus formation is identified as a potentially important contributor to changed material properties of the arterial wall. Understanding how the wall adapts and remodels its material properties in the face of changes in both the stress loading and blood constituents associated with infl- matory processes (IL6, CRP, MMPs, etc.

In an era wherein nanotechnology has sparked a huge research interest, brain drug delivery is not an exception. Aiming at fighting several central nervous system (CNS) conditions, tailored nanoparticles open new avenues to address several challenges in the fields of drug delivery and brain targeting. This book gathers contributions from experts in different, complementary fields, having in common their interest in developing new strategies for brain delivery based on nanotechnologies. The book encompasses general aspects pertaining to fundamental development, including tripartite in silico-in vitro-in vivo approaches. It also covers a diversity of nanomedicines applied in treatment and/or diagnosis and monitoring of CNS disorders. Aspects concerning their translation from the bench to clinical practice are also seamlessly discussed. This book will inspire readers to discover possible approaches to holistically delivering drugs into the brain. Edited by Carla Vitorino, Andreia Jorge and Alberto Pais, this book will appeal to anyone involved in nanomedicine, pharmaceutics, neurological and cancer therapies, drug delivery research and computational and regulatory sciences.

A textbook to teach nanoscale science and engineering to senior undergraduate and graduate students Ample solved examples and problems for the reader to understand the concepts and correlate fundamental science to nano-engineering Great source for researchers for information on fullerene structure, production methods, characterization, and properties The only book covering the state-of-the-art subject of 2D materials based on spherical fullerenes, single-walled carbon nanotubes, and graphene

Gets right to the point with step-by-step guidance on solving physics problems. Covers all topics in standard general physics courses in the same sequence. Keeps learning about physics fun and engaging through the story of dinosaurs being tested on their knowledge for a final challenge (deflecting an asteroid headed to Earth!). Enables the reader to quickly flip through and locate steps needed for a particular problem. Includes tons of easy to follow diagrams and worked solutions.

Presents an overview of current and developing treatment technologies for water polluted with emerging pollutants Gives in-depth account and analysis of advanced materials and methods for separation and treatment Reviews analytical techniques applied to detect emerging pollutants Discusses overall effect of policies on current chemicals/plastics/APIs in the market Includes pertinent case studies and regulations

Cryogen-free cryogenics is leading a revolution in research and industry by its significant advantages over traditional liquid helium systems. This is the first overview for the field, covering the key technologies, conceptual design, fabrication, operation, performance, and applications of these systems. The contents cover important topics such as the operating principles of 4 K cryocoolers, enabling technologies (including vibration reduction) for cryogen-free systems, the cryogen-free superconducting magnet, and cryogen-free systems that reach millikelvin. It highlights the wide range of applications in materials science, quantum physics, astronomy and space science, medical sciences, etc. Key features: * Introduces technologies and practical know-how employed for cryogen-free systems of using 4 K cryocoolers to replace liquid helium * Addresses state-of-the-art of cryogen-free superconducting magnets, subkelvin refrigeration systems of the He-3 sorption cooler, adiabatic demagnetization refrigerator (ADR) and dilution refrigerators (DR) * Discusses applications of cryogen-free systems in modern instruments and equipment

The scientific community and industry have seen tremendous progress in efficient energy production and storage in the last few years. With the advancement in technology, new devices require high-performance, stretchable, bendable, and twistable energy sources, which can be integrated into next-generation wearable, compact, and portable electronics for medical, military, and civilian applications. Smart and Flexible Energy Devices examines the materials, basic working principles, and state-of-the-art progress of flexible devices like fuel cells, solar cells, batteries, and supercapacitors. Covering the synthesis approaches for advanced energy materials in flexible devices and fabrications and fundamental design concepts of flexible energy devices, such as fuel cells, solar cells, batteries, and supercapacitors, top author teams explore how newer materials with advanced properties are used to fabricate the energy devices to meet the future demand for flexible electronics. Additional features include: * Addressing the materials, technologies, and challenges of various flexible energy devices under one cover * Emphasizing the future demand and challenges of the field * Considering all flexible energy types, such as fuel cells, solar cells, batteries, and supercapacitors * Suitability for undergraduate and postgraduate students of material science and energy programs This is a valuable resource for academics and industry professionals working in the field of energy materials, nanotechnology, and energy devices.

QSAR and SPECTRAL-SAR in Computational Ecotoxicology presents a collection of studies based on the epistemological bulk data-information-knowledge of the chemicals used in green chemistry. It assesses a specific model of pattern characterization of concerned active substances at the bio-, eco-, and pharmacologic levels through unitary formulation of the effector-receptor binding degree potential, including the logistic type by employing a computational algebraic quantitative structure-activity relationship (QSAR) model called SPECTRAL-SAR. It aims to minimize the residual recorded activities in the experiments that study the enzymic, ionic liquid, antagonists, and allosteric inhibition interactions. The book covers: The classic QSAR approach The new SPECTRAL-SAR approach How to draw SPECTRAL-SAR maps for predicting ecotoxicological mechanisms for a given series of toxicants and single or multi-species in an open system Biological activity as related to chemical reactivity through associate descriptors This book will be very useful in advanced courses on computational ecotoxicology, drug design and interaction, methods in quantum and computational chemistry, chemical molding, chemical bonding, and others.

This book gives a summary of the rapidly growing field of nanotechnology and includes materials and technologies that help in developing particles of various sizes, which can be utilized in different areas of research. It discusses the role of nanotechnology in different aspects, such as healthcare, especially in target-specific drug therapy for managing a number of medical disorders; agriculture, for developing smart field systems; and food industry, for improving and stabilizing the quality, healthiness, and shelf life of food. Being multidisciplinary, this book brings together the principles, theory, practices, and applications of not only nanotechnology but also those of nanobiotechnology, pharmaceuticals, food packaging, biosensors, and electronic devices. The book will be an exhilarating read for advanced undergraduate- and graduate-level students, general readers interested in nanotechnology, and researchers in chemistry, biology, and engineering. The scope of the book extends from basic research in physics, chemistry, and biology, including computational work and simulations, through to the development of new devices and technologies for applications in a wide range of industrial sectors (including information technology, medicine, manufacturing, high-performance materials, and energy and environmental technologies). It covers organic, inorganic, and hybrid materials and is an interdisciplinary book.

This book provides a well-focused and comprehensive overview of novel technologies involved in advanced microfluidics based diagnosis via various types of prognostic and diagnostic biomarkers. This authors examine microfluidics based diagnosis in the biomedical field as an upcoming field with extensive applications. It provides a unique approach and comprehensive technology overview for diagnosis management towards early stages of various bioanalytes via cancer diagnostics diabetes, alzheimer disease, toxicity in food products, brain and retinal diseases, cardiovascular diseases, and bacterial infections etc. Thus, this book would encompass a combinatorial approach of medical science, engineering and biomedical technology. The authors provide a well-focused and comprehensive overview of novel technologies involved in advanced microfluidics based diagnosis via various types of prognostic and diagnostic biomarkers. Moreover, this book contains detailed description on the diagnosis of novel techniques. This book would serve as a guide for students, scientists, researchers, and microfluidics based point of care technologies via smart diagnostics and to plan future research in this valuable field.

Advanced Chromatic Monitoring provides a major source of information about the novel approach of chromaticity with examples of how chromaticity may be deployed for various monitoring applications. It shows with examples what can be achieved with chromatic methods in producing relevant information with a variety of test techniques and in facilitating the interpretation of complex data about complicated situations. It will be of interest to postgraduates and researchers in a wide breadth of physical disciplines (engineering, medicine, environmental sciences) and those involved with data acquisition and analysis. Key Features: Applicable to a wide range of disciplines (engineering, medical, environmental, etc) and those interested in science, technology, data acquisition and analysis Provides an extrapolation of new knowledge well beyond that covered in existing literature with regard to dealing with complicated forms and sets of data Addresses inspiring and innovative areas of research including environmental, power delivery and medical monitoring About the Editors: Emeritus Professor Gordon R. Jones - founder and former Director of the Centre for Intelligent Monitoring Systems (CIMS), former Head of the Department of Electrical Engineering and Electronics, and former Director of Electric Arcs Research Group at the University of Liverpool. He was awarded the IEEE Education, Science and Technology Achievement Medal (1999). Professor Joe W. Spencer - the present Director of CIMS at the University of Liverpool, having been Head of the Department of Electrical Engineering and Electronics at Liverpool. He is involved in operating a multi-million pound technology transfer unit (Sensor City, Liverpool) with whose establishment he played a major role and with which CIMS has major interactions.

A New York Times bestselling writer explores what our unique sonic signature reveals about our species, our culture, and each one of us. Finally, a vital topic that has never had its own book gets its due. There's no shortage of books about public speaking or language or song. But until now, there has been no book about the miracle that underlies them all--the human voice itself. And there are few writers who could take on this surprisingly vast topic with more artistry and expertise than John Colapinto. Beginning with the novel--and compelling--argument that our ability to speak is what made us the planet's dominant species, he guides us from the voice's beginnings in lungfish millions of years ago to its culmination in the talent of Pavoratti, Martin Luther King Jr., and Beyonce--and each of us, every day. Along the way, he shows us why the voice is the most efficient, effective means of communication ever devised: it works in all directions, in all weathers, even in the dark, and it can be calibrated to reach one other person or thousands. He reveals why speech is the single most complex and intricate activity humans can perform. He travels up the Amazon to meet the Piraha, a reclusive tribe whose singular language, more musical than any other, can help us hear how melodic principles underpin every word we utter. He heads up to Harvard to see how professional voices are helped and healed, and he ventures out on the campaign trail to see how demagogues wield their voices as weapons. As far-reaching as this book is, much of the delight of reading it lies in how intimate it feels. Everything Colapinto tells us can be tested by our own lungs and mouths and ears and brains. He shows us that, for those who pay attention, the voice is an eloquent means of communicating not only what the speaker means, but also their mood, sexual preference, age, income, even psychological and physical illness. It overstates the case only slightly to say that anyone who talks, or sings, or listens will find a rich trove of thrills in This Is the Voice.

The era of Sustainable and Energy Efficient Nanoelectronics and Nanosystems has come. The research and development on Scalable and 3D integrated Diversified functions together with new computing architectures is in full swing. Besides data processing, data storage, new sensing modes and communication capabilities need the revision of process architecture to enable the Heterogeneous co integration of add-on devices with CMOS: the new defined functions and paradigms open the way to Augmented Nanosystems. The choices for future breakthroughs will request the study of new devices, circuits and computing architectures and to take new unexplored paths including as well new materials and integration schmes. This book reviews in two sections, including seven chapters, essential modules to build Diversified Nanosystems based on Nanoelectronics and finally how they pave the way to the definition of Nanofunctions for Augmented Nanosystems.

This book involves the topics on the frontier of the tissue engineering and regenerative medicine. It transits new ideas, new scientific results, and discusses on the design of the self-organized tissues. This book will have a broader readership, because it provides scientific information for diverse disciplinary fields (biology, material science, engineering, medicine, and life science). More scientists, professors, graduates, undergraduates and researchers would be inspired.This book will provide some 3D structure images that would impress the readers with intuitional and abundant information which includes experimental and simulative results.

This book is the closing report of the national priority program Nature-Inspired Fluid Mechanics (Schwerpunktprogramm SPP 1207: Stroemungsbeeinflussung in der Natur und Technik). Nature-inspired fluid mechanics is one subset of biomimetics, a discipline which has received increased attention over the last decade, with numerous faculties and degree courses devoted solely to exploring 'nature as a model' for engineering applications. To save locomotion energy, evolution has optimized the design of animals such that friction loss is minimized. In addition to many morphological adaptations, animals that are often exposed to water or air currents have developed special behaviors that allow them to use the energy contained in air or water fluctuations for energy savings. Such flow manipulation and control is not only important for many animals, but also for many engineering applications. Since living beings have been optimized by several million years of evolution it is very likely that many engineering disciplines can profit from the study of systems found in nature. Curiously, there has been little serious cross-disciplinary work and information exchange on the topic of fluid dynamics and flow control and this was the initial motivation to establish this national priority program.

This book is an up-to-date review of the most important plasma-based techniques for material modification, from microelectronics to biological materials and from fusion plasmas to atmospheric ones. Each its technical chapters is written by long-experienced, internationally recognised researchers. The book provides a deep and comprehensive insight into plasma technology and its associated elemental processes and is illustrated throughout with excellent figures and references to complement each section. Although some of the topics covered can be traced back several decades, care has been taken to emphasize the most recent findings and expected evolution. The first time the word 'plasma' appeared in print in a scientific text related to the study of electrical discharges in gases was 1928, when Irving Langmuir published his article 'Oscillations in Ionized Gases'. It was the baptism of the predominant state of matter in the known universe (it is estimated that up to 99% of matter is plasma), although not on earth, where the conditions of pressure and temperature make normal the states of matter (solid, liquid, gas) which, in global terms, are exotic. It is enough to add energy to a solid (in the form of heat or electromagnetic radiation) to go into the liquid state, from which gas is obtained through an additional supply of energy. If we continue adding energy to the gas, we will partially or totally ionise it and reach a new state of matter, plasma, made up of free electrons, atoms and molecules (electrically neutral particles) and ions (endowed with a positive or a negative electric charge).

MXene, a two-dimensional (2D) transition metal carbide, nitride, and carbonitride, was discovered in 2011. MXene has great potential as a cocatalyst in the field of photocatalysis due to its unique properties and structure. MXene-Based Photocatalysts: Fabrication and Applications introduces readers to the fundamentals, preparation, microstructure characterization, and a variety of applications of MXene-based photocatalysts. The book is a comprehensive reference for MXene materials and provides an overview of the current literature on MXene-based photocatalysts. FEATURES Discusses preparation methods of MXenes Describes the morphology and microstructure of MXenes Offers strategies for fabricating MXene-based photocatalysts Details the reaction mechanism of MXene-based photocatalysts Covers applications in photocatalytic water-splitting, photocatalytic CO2 reduction, photocatalytic degradation, photocatalytic nitrogen fixation, and photocatalytic H2O2 production This book serves as an invaluable guide for advanced students, industry professionals, professors, and researchers in the field of materials science and engineering, photocatalysis, energy, and environmental applications.

Principles of Adaptive Optics describes the foundations, principles, and applications of adaptive optics (AO) and its enabling technologies. This leading textbook addresses the fundamentals of AO at the core of astronomy, high-energy lasers, biomedical imaging, and optical communications. Key Features: Numerous examples to explain and support the underlying principles Hundreds of new references to support the topics that are addressed End-of-chapter questions and exercises A complete system design example threaded through each chapter as new material is introduced

In recent decades, luminescent nanomaterials have generated great interest in the scientific community due to their unique properties, which are different from those of their bulk counterparts, and their use in a wide variety of applications. Today, luminescent nanomaterials are used in a number of applications such as displays, solid-state lighting, solar cells, long afterglow, dosimetry, theft prevention, medical imaging, phototherapy, and quantum and gas sensing. This book presents cutting-edge research from experts in the field of synthesis and characterization of luminescent nanomaterials and their potential applications. It covers interesting topics in semiconductor physics, photochemistry, physical chemistry, materials science, and luminescence, and will be useful for beginners and advanced researchers interested in this field.

In recent years, optical properties of the unique atomic and molecular structures of materials have drawn great scientific interest. Linear optical properties of materials such as metals, metal oxides, magnetic oxides, and organic materials are based on energy transfer and find applications in wastewater treatment, forensic science, biomedical science, photovoltaics, nuclear technology, and LED displays. Nonlinear optical properties of materials are based on the nonlinear medium and find more advanced applications in frequency mixing generations and optical parametric oscillations. This book presents the underlying principles, implementation, and applications of the linear and nonlinear optical properties of materials and has been divided into two parts emphasizing these properties. The first part of the book, Linear Optics, discusses bimetallic nanoparticles in dielectric media and their integration to dye molecules to detect trace amounts of heavy metals at the nanometer level, as well as to enhance luminescence and image contrasts in forensic inspection and biomedical diagnosis. It shows how the integration of bimetallic nanoparticles into a ZnO matrix promotes broadening of the absorption spectrum from the ultraviolet to the visible wavelength. It explains the role of surface adsorption and photocatalytic degradation in dye-removal kinetics by Fe3O4 magnetic nanoparticles under pulsed white light. It also discusses the double-layer shielding tank design to safely store radioactive waste and photon propagation through the multilayer structures of a human tissue model. The second part of the book, Nonlinear Optics, presents general concepts such as electromagnetic theory, nonlinear medium, and wave propagation, as well as more advanced concepts such as second harmonic generation, phase matching, optical parametric interactions, different frequency generation, sum frequency generation, tunable laser, and optical resonant oscillator.

The International Conference on Phytochemistry, Textile, & Renewable Energy Technologies for Sustainable Development (ICPTRE 2020) was hosted by the World bank funded Africa Centre of Excellence in Phytochemicals, Textile and Renewable Energy (ACEII-PTRE) based at Moi University in conjunction with Donghua University, China and the Sino-Africa International Symposium on Textiles and Apparel (SAISTA). The theme of the conference was Advancing Science, Technology and Innovation for Industrial Growth. The research relationships between universities and industry have enabled the two entities to flourish and, in the past, have been credited for accelerated sustainable development and uplifting of millions out poverty. ICPTRE 2020 therefore provided a platform for academic researchers drawn from across the world to meet key industry professionals and actively share knowledge while advancing the role of research in industrial development, particularly, in the developing nations. The conference also provided exhibitors with an opportunity to interact with professionals and showcase their business, products, technologies and equipment. During the course of the conference, industrial exhibitions, research papers and presentations in the fields of phytochemistry, textiles, renewable energy, industry, science, technology, innovations and much more were presented.

System Innovation in a Post-Pandemic World contains the papers presented at the IEEE 7th International Conference on Applied System Innovation (ICASI 2021, Alishan, Taiwan, September 24-25, 2021). The conference received more than 200 submitted papers from 11 different countries, whereby roughly one third of these papers was selected by the committees and invited to present at ICASI 2021. The book provides an integrated communication platform for researchers from a wide range of disciplines including information technology, communication science, applied mathematics, computer science, advanced material science, and engineering. Hopefully, interdisciplinary collaborations between science and engineering technologists in the domains of academia and industry will be enhanced via this unique international network.

Forensic Chemistry, Third Edition, the new edition of this ground-breaking book, continues to serve as the leading forensic chemistry text on the market. Fully updated, this edition describes the latest advances in current forensic chemistry analysis and practice. New and expanded coverage includes rapid advances in forensic mass spectrometry, NMR, and novel psychoactive substances (NPSs). Topics related to seized drug analysis, toxicology, combustion and fire investigation, explosives, and firearms discharge residue are described and illustrated with case studies. The role of statistics, quality assurance/quality control, uncertainty, and metrology are integrated into all topics. More pharmacological and toxicokinetic calculations are presented and discussed. Hundreds of color figures, along with graphs, illustrations, worked example problems, and case descriptions are used to show how analytical chemistry is applied to forensic practice. Topics covered offer students insight into the legal context in which forensic chemistry is conducted and introduces them to the sample types and sample matrices encountered in forensic laboratories.

Our lives and well being intimately depend on the exploitation of the plant genetic resources available to our breeding programs. Therefore, more extensive exploration and effective exploitation of plant genetic resources are essential prerequisites for the release of improved cultivars. Accordingly, the remarkable progress in genomics approaches and more recently in sequencing and bioinformatics offers unprecedented opportunities for mining germplasm collections, mapping and cloning loci of interest, identifying novel alleles and deploying them for breeding purposes. This book collects 48 highly interdisciplinary articles describing how genomics improves our capacity to characterize and harness natural and artificially induced variation in order to boost crop productivity and provide consumers with high-quality food. This book will be an invaluable reference for all those interested in managing, mining and harnessing the genetic richness of plant genetic resources.