Medical science and practice have undergone fundamental changes in the last 5 years, as large-scale genome projects have resulted in the sequencing of a number of important microbial, plant and animal genomes. This book aims to combine industry standard software engineering and design principles with genomics, bioinformatics and cancer research. Rather than an exercise in learning a programming platform, the text focuses on useful analytical tools for the scientific community.

"Pro PHP XML and Web Services" is the authoritative guide to using the XML features of PHP 5 and PHP 6. No other book covers XML and Web Services in PHP as deeply as this title. The first four chapters introduce the core concepts of XML required for proficiency, and will bring you up to speed on the terminology and key concepts you need to proceed with the rest of the book. Next, the book explores utilizing XML and Web Services with PHP5. Topics include DOM, SimpleXML, SAX, xmlReader, XSLT, RDF, RSS, WDDX, XML-RPC, REST, SOAP, and UDDI.

Author Robert Richards, a major contributor to the PHP XML codebase, is a leading expert in the PHP community. In this book, Richards covers all topics in depth, blending theory with practical examples. You'll find case studies for the most popular web services like Amazon, Google, eBay, and Yahoo. The book also covers XML capabilities, demonstrated through informative examples, in the PEAR libraries.

As countless failures in information technology and Web-based systems are caused by an incorrect understanding of knowledge sharing, an increased awareness of modern, fundamental industry concepts becomes crucial to Web and interface developers. Web Engineering Advancements and Trends: Building New Dimensions of Information Technology examines integrated approaches in new dimensions of social and organizational knowledge sharing with emphasis on intelligent and personalized access. A defining collection of field advancements, this publication provides current research, applications, and techniques in testing and validation of Web systems.

In order to build a successful, Java-based application it is important to have a clear understanding of the principles underlying the various financial models. Those models guide the application designer in choosing the most appropriate Java data structures and implementation strategy. This book describes the principles of model building in financial engineering and explains those models as designs and working implementations for Java-based applications.

Throughout the book a series of packaged classes are developed to address a wide range of financial applications. Java methods are designed and implemented based on the most widely used models in financial engineering and investment practice. The classes and methods are explained and designed in a way which allows the financial engineer complete flexibility. The classes can be used as off-the-shelf working solutions or the innovative developer can re-arrange and modify methods to create new products

Praise for the previous edition:

'Gives an excellent insight into the main issues of creating a website and offers a good foundation of knowledge.' ? i.net

Producing for Web 2.0 is a clear and practical guide to the planning, set up and management of a website in web 2.0. It gives readers an overview of the current technologies available for online communications and shows how to use them for maximum effect when planning a website.

Producing for Web 2.0 sets out the practical toolkit needed for web design and content management. It is supported by a regularly updated and comprehensive Companion Website at: www.producingforweb2.com where readers can see examples of programming and demonstrations of concepts discussed in the book, as well as trying things out themselves.

Producing for Web 2.0 includes:

• illustrated examples of good design and content
• advice on content, maintenance and how to use sites effectively
• tips on using multimedia, including video, audio, flash, and images
• a chapter on ethics and internet regulations for journalists and writers
• tutorials for the main applications used in website design
• step by step guides to difficult areas with screenshots
• guides to good practice for all those involved in publishing news online.

Web-based Support Systems (WSS) are an emerging multidisciplinary research area in which one studies the support of human activities with the Web as the common platform, mediumandinterface.TheInternetaffectseveryaspectofourmodernlife. Moving support systems to online is an increasing trend in many research domains. One of the goals of WSS research is to extend the human physical limitation of information processing in the information age. Research on WSS is motivated by the challenges and opportunities arising from the Internet. The availability, accessibility and ?exibility of information as well as the tools to access this information lead to a vast amount of opportunities. H- ever, there are also many challenges we face. For instance, we have to deal with more complex tasks, as there are increasing demands for quality and productivity. WSS research is a natural evolution of the studies on various computerized support systems such as Decision Support Systems (DSS), Computer Aided Design (CAD), and Computer Aided Software Engineering (CASE). The recent advancement of computer and Web technologies make the implementation of more feasible WSS. Nowadays, it is rare to see a system without some type of Web interaction. The research of WSS is classi?ed into four groups. WSS for speci?c domains."

"One of the most significant books in my life." -Obie Fernandez, Author, The Rails Way "Twenty years ago, the first edition of The Pragmatic Programmer completely changed the trajectory of my career. This new edition could do the same for yours." -Mike Cohn, Author of Succeeding with Agile , Agile Estimating and Planning , and User Stories Applied ". . . filled with practical advice, both technical and professional, that will serve you and your projects well for years to come." -Andrea Goulet, CEO, Corgibytes, Founder, LegacyCode.Rocks ". . . lightning does strike twice, and this book is proof." -VM (Vicky) Brasseur, Director of Open Source Strategy, Juniper Networks The Pragmatic Programmer is one of those rare tech books you'll read, re-read, and read again over the years. Whether you're new to the field or an experienced practitioner, you'll come away with fresh insights each and every time. Dave Thomas and Andy Hunt wrote the first edition of this influential book in 1999 to help their clients create better software and rediscover the joy of coding. These lessons have helped a generation of programmers examine the very essence of software development, independent of any particular language, framework, or methodology, and the Pragmatic philosophy has spawned hundreds of books, screencasts, and audio books, as well as thousands of careers and success stories. Now, twenty years later, this new edition re-examines what it means to be a modern programmer. Topics range from personal responsibility and career development to architectural techniques for keeping your code flexible and easy to adapt and reuse. Read this book, and you'll learn how to: Fight software rot Learn continuously Avoid the trap of duplicating knowledge Write flexible, dynamic, and adaptable code Harness the power of basic tools Avoid programming by coincidence Learn real requirements Solve the underlying problems of concurrent code Guard against security vulnerabilities Build teams of Pragmatic Programmers Take responsibility for your work and career Test ruthlessly and effectively, including property-based testing Implement the Pragmatic Starter Kit Delight your users Written as a series of self-contained sections and filled with classic and fresh anecdotes, thoughtful examples, and interesting analogies, The Pragmatic Programmer illustrates the best approaches and major pitfalls of many different aspects of software development. Whether you're a new coder, an experienced programmer, or a manager responsible for software projects, use these lessons daily, and you'll quickly see improvements in personal productivity, accuracy, and job satisfaction. You'll learn skills and develop habits and attitudes that form the foundation for long-term success in your career. You'll become a Pragmatic Programmer. Register your book for convenient access to downloads, updates, and/or corrections as they become available. See inside book for details.

The SGML FAQ Book: Understanding the Foundation of HTML and XML is similar, but not quite the same kind of thing as an online FAQ or Frequently Asked Questions' list. It addresses questions from people who already actually use SGML in some way (including HTML authors), and people who are about to use it. It deals mainly with issues that arise when using SGML in practice. A very brief introduction to SGML is included as Appendix A. The questions discussed in The SGML FAQ Book are repeatedly heard by people who make their living serving the SGML community. SGML experts spend many hours teaching these details, sometimes repeatedly because some questions do not seem important - until you run into them. So one benefit of this book is learning more of the art of document creation and management, both by general reading before questions arise and by specific reference when a question arises. For the latter use, the appendices, glossary, and index are particularly important. A second benefit of this book is that it provides a common theme to its answers that you can apply in your use of SGML, HTML and related languages in general. The fundamental answer to many of the questions boils down to simplify': many questions do not show up if you use the simple, elegant core of SGML without worrying about optional features. The credo of this book is simply, SGML doesn't need to be complicated'. SGML has the potential for complexity at certain points. But much of the complexity comes from optional parts and can be avoided. SGML methodology and its primary benefits suffer no loss even if you skip many features, which speaks well for the quality of SGML's overall design. Many of the questions discussedinvolve those optional parts, and therefore can be avoided by judicious designers and authors. The two key goals of the book are (1) to answer questions that you may actually encounter as an SGML user, and to help you get unstuck' and be as productive as possible in using the language and (2) to show proactive ways you can simplify your use of SGML, and get its very substantial benefits with minimal complexity.

E-Government Website Development: Future Trends and Strategic Models focuses on three foundational aspects of e-government Web sites, namely concepts or theories that influence e-government Web site development, description and analysis of e-government Web site experience from different national perspectives, and possible models that might provide direction for future e-government development. The authors brilliantly incorporate a combination of basic concepts that will guide future development of governmental Web sites, descriptive research about the state of e-government in various parts of the world, and a specific prescription for the future of e-government Web sites into one essential compilation.

With the increasing proliferation of information-technology and, especially, Web-based approaches to the implementation of systems and services, researchers, educators, and practitioners worldwide are experiencing a rising need for authoritative references to enhance their understanding of the most current and effective engineering practices leading to robust and successful solutions.""Integrated Approaches in Information Technology and Web Engineering: Advancing Organizational Knowledge Sharing"" presents comprehensive, research-driven insights into the field of Web engineering. This book collects over 30 authoritative articles from distinguished international researchers in information technology and Web engineering, creating an invaluable resource for library reference collections that will equip researchers and practitioners in academia and industry alike with the knowledge base to drive the next generation of innovations.

Java is an exciting new object-oriented technology. Hardware for supporting objects and other features of Java such as multithreading, dynamic linking and loading is the focus of this book. The impact of Java's features on micro-architectural resources and issues in the design of Java-specific architectures are interesting topics that require the immediate attention of the research community. While Java has become an important part of desktop applications, it is now being used widely in high-end server markets, and will soon be widespread in low-end embedded computing.

Java Microarchitectures contains a collection of papers providing a snapshot of the state of the art in hardware support for Java. The book covers the behavior of Java applications, embedded processors for Java, memory system design, and high-performance single-chip architectures designed to execute Java applications efficiently.

The book provides complete coverage of fundamental IP networking in Java. It introduces the concepts behind TCP/IP and UDP and their intended use and purpose; gives complete coverage of Java networking APIs, includes an extended discussion of advanced server design, so that the various design principles and tradeoffs concerned are discussed and equips the reader with analytic queuing-theory tools to evaluate design alternatives; covers UDP multicasting, and covers multi-homed hosts, leading the reader to understand the extra programming steps and design considerations required in such environments.

After reading this book the reader will have an advanced knowledge of fundamental network design and programming concepts in the Java language, enabling them to design and implement distributed applications with advanced features and to predict their performance. Special emphasis is given to the scalable I/O facilities of Java 1.4 as well as complete treatments of multi-homing and UDP both unicast and multicast.

In recent years, the emerging field of agent technologies has become mainstream in Web engineering. With constant field developments and updates, a reference source is needed that reflects the increased scope of agent technology application domains and development practices and tools. ""Agent Technologies and Web Engineering: Applications and Systems"" presents the latest tools and applications addressing critical issues involved with information technology and Web engineering research. Covering topics such as next-generation networks, XML query processing, and Semantic Web services, this book provides cutting-edge research for practitioners and academicians involved in agent technology and Web engineering fields.

Voice recognition is here at last. Alexa and other voice assistants have now become widespread and mainstream. Is your app ready for voice interaction? Learn how to develop your own voice applications for Amazon Alexa. Start with techniques for building conversational user interfaces and dialog management. Integrate with existing applications and visual interfaces to complement voice-first applications. The future of human-computer interaction is voice, and we'll help you get ready for it. For decades, voice-enabled computers have only existed in the realm of science fiction. But now the Alexa Skills Kit (ASK) lets you develop your own voice-first applications. Leverage ASK to create engaging and natural user interfaces for your applications, enabling them to listen to users and talk back. You'll see how to use voice and sound as first-class components of user-interface design. We'll start with the essentials of building Alexa voice applications, called skills, including useful tools for creating, testing, and deploying your skills. From there, you can define parameters and dialogs that will prompt users for input in a natural, conversational style. Integrate your Alexa skills with Amazon services and other backend services to create a custom user experience. Discover how to tailor Alexa's voice and language to create more engaging responses and speak in the user's own language. Complement the voice-first experience with visual interfaces for users on screen-based devices. Add options for users to buy upgrades or other products from your application. Once all the pieces are in place, learn how to publish your Alexa skill for everyone to use. Create the future of user interfaces using the Alexa Skills Kit today. What You Need: You will need a computer capable of running the latest version of Node.js, a Git client, and internet access.

DESCRIPTION Distributed systems are unpredictable, and it can be an enormous challenge to manage around potentially-crippling obstacles like hardware failures, unanticipated changes in load, and network issues. Amazon Web Services (AWS) is a platform for hosting distributed applications in a secure, flexible cloud environment. AWS provides a suite of services designed to keep the focus on what an application does instead of the infrastructure required to run it. Whether serving up blog pages, analyzing fast data in real-time, building software as a service, or implementing a massive e-commerce site, AWS provides both a stable platform and services that will scale with every application. Amazon Web Services in Action introduces readers to computing, storing, and networking in the AWS cloud. It starts with a broad overview of AWS, and shows how to spin up servers manually and from the command line. Then, it explores infrastructure automation with the AWS CloudFormation service, where readers can describe a blueprint of their infrastructure as code. Readers will learn how to isolate systems using private networks to increase security, how to use the most valuable AWS managed services available on AWS, and about the benefits of stateless servers. In the end, they'll look to the AWS model for high availability, scaling, decoupling with queues and load balancers, and fault tolerance. KEY SELLING POINTS Explains the key concepts of AWS Gives an overview of the most important services Allows readers to take full advantage of the AWS platform AUDIENCE Written for developers and DevOps engineers who are moving traditionally-deployed distributed applications to the AWS platform. No experience with AWS is required. ABOUT THE TECHNOLOGY Amazon Web Services is a platform of services in the Cloud to provide everything needed to run applications-from hosting a private blog, to running one of the biggest websites on earth, analyzing data for cancer research, or providing business applications.

Is the Enterprise Information Portal (EIP) knowledge management's killer app? Leading expert Joseph M. Firestone, the first author to formulate the idea of the Enterprise Knowledge Portal, breaks new ground and looks to the future with a practical, but comprehensive approach to enterprise portals and their relationship to knowledge management. Providing a clear and novel overview, Firestone tackles a wide range of topics ranging from functional EIP applications, estimating costs and benefits of EIPs, variations in EIP technical architecture, the role of intelligent agents, the nature of knowledge management, portal product/solution segmentation, portal product case studies, to the future of the EIP space.
'Enterprise Information Portals and Knowledge Management' is the book on portals you've been waiting for. It is the only book that thoroughly considers, explores, and analyzes:
* The EIP orientation, outlook and evolution
* A new methodology for estimating EIP benefits and costs
* EIP and Enterprise Knowledge Portals (EKP) architecture
* The approaching role of software agents in EIPs and EKPs
* The current and future contribution of EIP and EKP solutions to Knowledge Management
* The role of XML in portal architecture
* A comprehensive, multi-dimensional, and forward-looking segmentation of EIP products accompanied by portal product case studies
* Where EIP sector companies are headed and the pathways they will follow to get there
* Comprehensive approach to enterprise portals and their relationship to knowledge management
* Groundbreaking author, Firestone was the first to formulate the idea of the Enterprise Knowledge Portal
* Tackles a widerange of topics from functional EIP applications, estimating costs and benefits of EIPs, variations in EIP technical architecture, the role of intelligent agents, the nature of knowledge management, portal product/solution segmentation, portal product case studies, to the future of the EIP space

The only beginning book of its kind, this book will teach you SAP/ABAP developers the skills you need for Java 5 programming. The book emphasizes the fundamentals of core Java SE 5 and Java EE 5, to get you up to speed with these technologies. You'll learn about the most important enterprise Java API found in the new Java EE 5 platform, which you can immediately use and integrate. Furthermore, the book elaborates on connecting to a database, SAP Java Connector, servlets, Java Server Pages, Enterprise JavaBeans, and Java Messaging.

Cay Horstmann s seventh edition of Java Concepts provides an approachable introduction to fundamental programming techniques and design skills, helping students master basic concepts and become competent coders. Major rewrites and an updated visual design make this student-friendly text even more engaging. The text is known for its realistic programming examples, great quantity and variety of homework assignments, and lab exercises that build student problem-solving abilities. The seventh edition now includes problem solving sections, more example code online, and exercises from Science and Business.

It demonstrates how features such as animation and audio can be employed to ensure web sites are used to their full potential and therefore helps to create professional products that will secure a positive image of the company or product they are promoting. It is accessible and simplifies the authoring experience so that even those with little or no previous knowledge of creating web pages can develop and innovate stimulating and interactive features to enhance their content.

Part of the highly successful Shelly Cashman Series (R), this text provides an introduction to HTML5 and CSS and leads the user through a clear, step-by-step, screen-by-screen approach to learning. Readers learn how to create a Web page using HTML5, format the page, add graphics, and more.

This book is for novices If you have never done any programming before - if you are a complete novice - this book is for you. This book assumes no prior knowledge of programming. It starts from scratch. It is written in a simple, direct style for maximum clarity. It is aimed at first level students at universities and colleges, but it is also suitable for novices studying alone. The approach of this book We explain how to use objects early in this book. Our approach is to start with the ideas of variables, assignment and methods, then introduce the use of objects created from library classes. Next we explain how to use control structures for selection and looping. Then comes the treatment of how to write your own classes. We wanted to make sure that the fun element of programming was paramount, so we use graphics right from the start. We think graphics is fun, interesting and clearly demonstrates all the important principles of programming. But we haven't ignored programs that input and output text - they are also included. The programs we present use many of the features of a graphical user interfaces (GUIs), such as buttons, scroll bars and text boxes. But we also explain how to write console programs in Java. We introduce new ideas carefully one-at-a-time, rather than all at once. So, for example, there is a single chapter on writing methods. We introduce simple ideas early and more sophisticated ideas later on.

"Expert ASP.NET 2.0 Advanced Application Design" will help you derive maximum performance and reliability from the distributed applications you create with ASP.NET 2.0.

The book first looks at some of the non-functional requirements that impact the design of a distributed application. It then relates them to the servers and services available in the .NET 2.0 Framework. ASP.NET 2.0 is the central process for use in distributed .NET applications, and the book closely examines the ASP.NET 2.0 Framework and its hosting environment, Internet Information Server (IIS). The book looks at how ASP.NET 2.0 is used by different packages within .NET (like Web Services), and explores how it can be extended to meet your own custom requirements.

The second part of the book drills down and examines some of the common architectural challenges encountered when developing application designs. The book walks through the tiers of the .NET Framework, starting at the client level and exploring the internals of the page type, enhancements to ViewState, client script generation, and new out-of-band callbacks. At the middle tier, the book examines Web Services, Remoting, COM+, MSMQ, and mix and match communication options to suit your own requirements. This section wraps up by previewing Windows Communication Foundation, which aims to unify these technologies.

The third part of the book examines the data layer of your distributed applications. This includes enhancements to the Managed Providers in 2.0, the new transactional model, and a preview of usage guidelines for SQL Server 2005. By the books conclusion, you will be able to select with confidence the most appropriate design elements for yourpurposes, elegantly connecting them, and ensuring you get the very best from the ASP.NET 2.0 Framework.