Medical science and practice have undergone fundamental changes in the last 5 years, as large-scale genome projects have resulted in the sequencing of a number of important microbial, plant and animal genomes. This book aims to combine industry standard software engineering and design principles with genomics, bioinformatics and cancer research. Rather than an exercise in learning a programming platform, the text focuses on useful analytical tools for the scientific community.

As countless failures in information technology and Web-based systems are caused by an incorrect understanding of knowledge sharing, an increased awareness of modern, fundamental industry concepts becomes crucial to Web and interface developers. Web Engineering Advancements and Trends: Building New Dimensions of Information Technology examines integrated approaches in new dimensions of social and organizational knowledge sharing with emphasis on intelligent and personalized access. A defining collection of field advancements, this publication provides current research, applications, and techniques in testing and validation of Web systems.

"Pro PHP XML and Web Services" is the authoritative guide to using the XML features of PHP 5 and PHP 6. No other book covers XML and Web Services in PHP as deeply as this title. The first four chapters introduce the core concepts of XML required for proficiency, and will bring you up to speed on the terminology and key concepts you need to proceed with the rest of the book. Next, the book explores utilizing XML and Web Services with PHP5. Topics include DOM, SimpleXML, SAX, xmlReader, XSLT, RDF, RSS, WDDX, XML-RPC, REST, SOAP, and UDDI.

Author Robert Richards, a major contributor to the PHP XML codebase, is a leading expert in the PHP community. In this book, Richards covers all topics in depth, blending theory with practical examples. You'll find case studies for the most popular web services like Amazon, Google, eBay, and Yahoo. The book also covers XML capabilities, demonstrated through informative examples, in the PEAR libraries.

In order to build a successful, Java-based application it is important to have a clear understanding of the principles underlying the various financial models. Those models guide the application designer in choosing the most appropriate Java data structures and implementation strategy. This book describes the principles of model building in financial engineering and explains those models as designs and working implementations for Java-based applications.

Throughout the book a series of packaged classes are developed to address a wide range of financial applications. Java methods are designed and implemented based on the most widely used models in financial engineering and investment practice. The classes and methods are explained and designed in a way which allows the financial engineer complete flexibility. The classes can be used as off-the-shelf working solutions or the innovative developer can re-arrange and modify methods to create new products

Web-based Support Systems (WSS) are an emerging multidisciplinary research area in which one studies the support of human activities with the Web as the common platform, mediumandinterface.TheInternetaffectseveryaspectofourmodernlife. Moving support systems to online is an increasing trend in many research domains. One of the goals of WSS research is to extend the human physical limitation of information processing in the information age. Research on WSS is motivated by the challenges and opportunities arising from the Internet. The availability, accessibility and ?exibility of information as well as the tools to access this information lead to a vast amount of opportunities. H- ever, there are also many challenges we face. For instance, we have to deal with more complex tasks, as there are increasing demands for quality and productivity. WSS research is a natural evolution of the studies on various computerized support systems such as Decision Support Systems (DSS), Computer Aided Design (CAD), and Computer Aided Software Engineering (CASE). The recent advancement of computer and Web technologies make the implementation of more feasible WSS. Nowadays, it is rare to see a system without some type of Web interaction. The research of WSS is classi?ed into four groups. WSS for speci?c domains."

The SGML FAQ Book: Understanding the Foundation of HTML and XML is similar, but not quite the same kind of thing as an online FAQ or Frequently Asked Questions' list. It addresses questions from people who already actually use SGML in some way (including HTML authors), and people who are about to use it. It deals mainly with issues that arise when using SGML in practice. A very brief introduction to SGML is included as Appendix A. The questions discussed in The SGML FAQ Book are repeatedly heard by people who make their living serving the SGML community. SGML experts spend many hours teaching these details, sometimes repeatedly because some questions do not seem important - until you run into them. So one benefit of this book is learning more of the art of document creation and management, both by general reading before questions arise and by specific reference when a question arises. For the latter use, the appendices, glossary, and index are particularly important. A second benefit of this book is that it provides a common theme to its answers that you can apply in your use of SGML, HTML and related languages in general. The fundamental answer to many of the questions boils down to simplify': many questions do not show up if you use the simple, elegant core of SGML without worrying about optional features. The credo of this book is simply, SGML doesn't need to be complicated'. SGML has the potential for complexity at certain points. But much of the complexity comes from optional parts and can be avoided. SGML methodology and its primary benefits suffer no loss even if you skip many features, which speaks well for the quality of SGML's overall design. Many of the questions discussedinvolve those optional parts, and therefore can be avoided by judicious designers and authors. The two key goals of the book are (1) to answer questions that you may actually encounter as an SGML user, and to help you get unstuck' and be as productive as possible in using the language and (2) to show proactive ways you can simplify your use of SGML, and get its very substantial benefits with minimal complexity.

E-Government Website Development: Future Trends and Strategic Models focuses on three foundational aspects of e-government Web sites, namely concepts or theories that influence e-government Web site development, description and analysis of e-government Web site experience from different national perspectives, and possible models that might provide direction for future e-government development. The authors brilliantly incorporate a combination of basic concepts that will guide future development of governmental Web sites, descriptive research about the state of e-government in various parts of the world, and a specific prescription for the future of e-government Web sites into one essential compilation.

With the increasing proliferation of information-technology and, especially, Web-based approaches to the implementation of systems and services, researchers, educators, and practitioners worldwide are experiencing a rising need for authoritative references to enhance their understanding of the most current and effective engineering practices leading to robust and successful solutions.""Integrated Approaches in Information Technology and Web Engineering: Advancing Organizational Knowledge Sharing"" presents comprehensive, research-driven insights into the field of Web engineering. This book collects over 30 authoritative articles from distinguished international researchers in information technology and Web engineering, creating an invaluable resource for library reference collections that will equip researchers and practitioners in academia and industry alike with the knowledge base to drive the next generation of innovations.

Java is an exciting new object-oriented technology. Hardware for supporting objects and other features of Java such as multithreading, dynamic linking and loading is the focus of this book. The impact of Java's features on micro-architectural resources and issues in the design of Java-specific architectures are interesting topics that require the immediate attention of the research community. While Java has become an important part of desktop applications, it is now being used widely in high-end server markets, and will soon be widespread in low-end embedded computing.

Java Microarchitectures contains a collection of papers providing a snapshot of the state of the art in hardware support for Java. The book covers the behavior of Java applications, embedded processors for Java, memory system design, and high-performance single-chip architectures designed to execute Java applications efficiently.

In recent years, the emerging field of agent technologies has become mainstream in Web engineering. With constant field developments and updates, a reference source is needed that reflects the increased scope of agent technology application domains and development practices and tools. ""Agent Technologies and Web Engineering: Applications and Systems"" presents the latest tools and applications addressing critical issues involved with information technology and Web engineering research. Covering topics such as next-generation networks, XML query processing, and Semantic Web services, this book provides cutting-edge research for practitioners and academicians involved in agent technology and Web engineering fields.

The book provides complete coverage of fundamental IP networking in Java. It introduces the concepts behind TCP/IP and UDP and their intended use and purpose; gives complete coverage of Java networking APIs, includes an extended discussion of advanced server design, so that the various design principles and tradeoffs concerned are discussed and equips the reader with analytic queuing-theory tools to evaluate design alternatives; covers UDP multicasting, and covers multi-homed hosts, leading the reader to understand the extra programming steps and design considerations required in such environments.

After reading this book the reader will have an advanced knowledge of fundamental network design and programming concepts in the Java language, enabling them to design and implement distributed applications with advanced features and to predict their performance. Special emphasis is given to the scalable I/O facilities of Java 1.4 as well as complete treatments of multi-homing and UDP both unicast and multicast.

The Web is causing a revolution in how we represent, retrieve, and process information Its growth has given us a universally accessible database but in the form of a largely unorganized collection of documents. This is changing, thanks to the simultaneous emergence of new ways of representing data: from within the Web community, XML; and from within the database community, semistructured data. The convergence of these two approaches has rendered them nearly identical. Now, there is a concerted effort to develop effective techniques for retrieving and processing both kinds of data.
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Data on the Web" is the only comprehensive, up-to-date examination of these rapidly evolving retrieval and processing strategies, which are of critical importance for almost all Web- and data-intensive enterprises. This book offers detailed solutions to a wide range of practical problems while equipping you with a keen understanding of the fundamental issues including data models, query languages, and schemas involved in their design, implementation, and optimization. You'll find it to be compelling reading, whether your interest is that of a practitioner involved in a database-driven Web enterprise or a researcher in computer science or related field.
* Provides an in-depth look at XML and other technologies for publishing structured documents on the Web.
* Examines recently developed methods for querying and updating structured Web documents and semistructured data, including XML-QL and XSL.
* Looks deeper into the convergence of Web and database approaches to semistructured data presentation and querying.
* Details practical examples of how these techniques are already being applied and how they will be used in the near future.
* Teaches sound techniques for writing queries over Web data, describing loose schemas over partially structured data, and implementing and optimizing queries on semistructured data."

"I was fortunate indeed to have worked with a fantastic team on the design and implementation of the concurrency features added to the Java platform in Java 5.0 and Java 6. Now this same team provides the best explanation yet of these new features, and of concurrency in general. Concurrency is no longer a subject for advanced users only. Every Java developer should read this book."
--Martin Buchholz
JDK Concurrency Czar, Sun Microsystems

"For the past 30 years, computer performance has been driven by Moore's Law; from now on, it will be driven by Amdahl's Law. Writing code that effectively exploits multiple processors can be very challenging. "Java Concurrency in Practice" provides you with the concepts and techniques needed to write safe and scalable Java programs for today's--and tomorrow's--systems."
--Doron Rajwan
Research Scientist, Intel Corp

"This is the book you need if you're writing--or designing, or debugging, or maintaining, or contemplating--multithreaded Java programs. If you've ever had to synchronize a method and you weren't sure why, you owe it to yourself and your users to read this book, cover to cover."
--Ted Neward
Author of "Effective Enterprise Java"

"Brian addresses the fundamental issues and complexities of concurrency with uncommon clarity. This book is a must-read for anyone who uses threads and cares about performance."
--Kirk Pepperdine
CTO, JavaPerformanceTuning.com

"This book covers a very deep and subtle topic in a very clear and concise way, making it the perfect Java Concurrency reference manual. Each page is filled with the problems (and solutions!) that programmers struggle with every day. Effectively exploitingconcurrency is becoming more and more important now that Moore's Law is delivering more cores but not faster cores, and this book will show you how to do it."
--Dr. Cliff Click
Senior Software Engineer, Azul Systems

"I have a strong interest in concurrency, and have probably written more thread deadlocks and made more synchronization mistakes than most programmers. Brian's book is the most readable on the topic of threading and concurrency in Java, and deals with this difficult subject with a wonderful hands-on approach. This is a book I am recommending to all my readers of "The Java Specialists' Newsletter," because it is interesting, useful, and relevant to the problems facing Java developers today."
--Dr. Heinz Kabutz
"The Java Specialists' Newsletter"

"I've focused a career on simplifying simple problems, but this book ambitiously and effectively works to simplify a complex but critical subject: concurrency. "Java Concurrency in Practice" is revolutionary in its approach, smooth and easy in style, and timely in its delivery--it's destined to be a very important book."
--Bruce Tate
Author of "Beyond Java"

""Java Concurrency in Practice" is an invaluable compilation of threading know-how for Java developers. I found reading this book intellectually exciting, in part because it is an excellent introduction to Java's concurrency API, but mostly because it captures in a thorough and accessible way expert knowledge on threading not easily found elsewhere."
--Bill Venners
Author of "Inside the Java Virtual Machine"

Threads are a fundamental part of the Java platform. As multicore processors become the norm, using concurrency effectively becomes essential forbuilding high-performance applications. Java SE 5 and 6 are a huge step forward for the development of concurrent applications, with improvements to the Java Virtual Machine to support high-performance, highly scalable concurrent classes and a rich set of new concurrency building blocks. In "Java Concurrency in Practice," the creators of these new facilities explain not only how they work and how to use them, but also the motivation and design patterns behind them.

However, developing, testing, and debugging multithreaded programs can still be very difficult; it is all too easy to create concurrent programs that appear to work, but fail when it matters most: in production, under heavy load. "Java Concurrency in Practice" arms readers with both the theoretical underpinnings and concrete techniques for building reliable, scalable, maintainable concurrent applications. Rather than simply offering an inventory of concurrency APIs and mechanisms, it provides design rules, patterns, and mental models that make it easier to build concurrent programs that are both correct and performant.

This book covers: Basic concepts of concurrency and thread safety Techniques for building and composing thread-safe classes Using the concurrency building blocks in java.util.concurrent Performance optimization dos and don'ts Testing concurrent programs Advanced topics such as atomic variables, nonblocking algorithms, and the Java Memory Model

This book develops the object-oriented programming skills of experienced programmers (at the Junior, Senior or above level) by showing how to use Java 2 (the latest release of Sun's Java platform), and by providing a complete understanding of the philosophy behind Java 2. It starts out covering the language-independent concepts that are at the heart of the Java world, and then moves on to introduce Java through several example programs. Following this is an in-depth discussion on inheritance and polymorphism. Finally, the book concludes with material on important features of Java that are not object-oriented.

The only beginning book of its kind, this book will teach you SAP/ABAP developers the skills you need for Java 5 programming. The book emphasizes the fundamentals of core Java SE 5 and Java EE 5, to get you up to speed with these technologies. You'll learn about the most important enterprise Java API found in the new Java EE 5 platform, which you can immediately use and integrate. Furthermore, the book elaborates on connecting to a database, SAP Java Connector, servlets, Java Server Pages, Enterprise JavaBeans, and Java Messaging.

Cay Horstmann s seventh edition of Java Concepts provides an approachable introduction to fundamental programming techniques and design skills, helping students master basic concepts and become competent coders. Major rewrites and an updated visual design make this student-friendly text even more engaging. The text is known for its realistic programming examples, great quantity and variety of homework assignments, and lab exercises that build student problem-solving abilities. The seventh edition now includes problem solving sections, more example code online, and exercises from Science and Business.

Part of the highly successful Shelly Cashman Series (R), this text provides an introduction to HTML5 and CSS and leads the user through a clear, step-by-step, screen-by-screen approach to learning. Readers learn how to create a Web page using HTML5, format the page, add graphics, and more.

"Expert ASP.NET 2.0 Advanced Application Design" will help you derive maximum performance and reliability from the distributed applications you create with ASP.NET 2.0.

The book first looks at some of the non-functional requirements that impact the design of a distributed application. It then relates them to the servers and services available in the .NET 2.0 Framework. ASP.NET 2.0 is the central process for use in distributed .NET applications, and the book closely examines the ASP.NET 2.0 Framework and its hosting environment, Internet Information Server (IIS). The book looks at how ASP.NET 2.0 is used by different packages within .NET (like Web Services), and explores how it can be extended to meet your own custom requirements.

The second part of the book drills down and examines some of the common architectural challenges encountered when developing application designs. The book walks through the tiers of the .NET Framework, starting at the client level and exploring the internals of the page type, enhancements to ViewState, client script generation, and new out-of-band callbacks. At the middle tier, the book examines Web Services, Remoting, COM+, MSMQ, and mix and match communication options to suit your own requirements. This section wraps up by previewing Windows Communication Foundation, which aims to unify these technologies.

The third part of the book examines the data layer of your distributed applications. This includes enhancements to the Managed Providers in 2.0, the new transactional model, and a preview of usage guidelines for SQL Server 2005. By the books conclusion, you will be able to select with confidence the most appropriate design elements for yourpurposes, elegantly connecting them, and ensuring you get the very best from the ASP.NET 2.0 Framework.

The papers in this volume aim at obtaining a common understanding of the challenging research questions in web applications comprising web information systems, web services, and web interoperability; obtaining a common understanding of verification needs in web applications; achieving a common understanding of the available rigorous approaches to system development, and the cases in which they have succeeded; identifying how rigorous software engineering methods can be exploited to develop suitable web applications; and at developing a European-scale research agenda combining theory, methods and tools that would lead to suitable web applications with the potential to implement systems for computation in the public domain.

Is there an easier way to build and deliver rich internet applications (RIAs) other than the Flash IDE or Ajax? Absolutely. With Adobe Flex 2, the Flex 2 SDK, and this book, you have all you need to build RIAs. "Programming Flex 2" offers you plenty of practical and useful examples that reveal how and why to use a particular feature of Flex 2, and when and when not to. As part of the Adobe Developer Library, "Programming Flex 2" is the authoritative guide to this new Adobe framework. You learn to use a markup language called MXML and a vast library of off-the-shelf and highly-configurable components to build Flash-based applications that combine the immediacy of the Web with the functionality and responsiveness of desktop applications. You also discover why - with the Flash Player runtime environment and the powerful ActionScript 3.0 programming language - the possibilities with Flex 2 are nearly limitless. The topics include: Managing Layout; Working with Components; Working with Media; Managing State; Using Transitions and Effects; Working with Data; Customizing Application Appearance; Client Data Communication and Remote Data Communication; Debugging Flex Framework Applications; and Creating Custom Components. Flex may be easier to learn than the Flash IDE, but you still need a reliable guide to the framework. "Programming Flex 2" not only serves as a reference, but provides valuable and practical insight into this new technology. As you learn how to build Flex applications, you'll also discover how Flex works. This book supplies all the information you need in one convenient place.

100 Go Mistakes: How to Avoid Them introduces dozens of techniques for writing idiomatic, expressive, and efficient Go code that avoids common pitfalls. By reviewing dozens of interesting, readable examples and real-world case studies, you'll explore mistakes that even experienced Go programmers make. This book is focused on pure Go code, with standards you can apply to any kind of project. As you go, you'll navigate the tricky bits of handling JSON data and HTTP services, discover best practices for Go code organization, and learn how to use slices efficiently. Your code speed and quality will enjoy a huge boost when you improve your concurrency skills, deal with error management idiomatically, and increase the quality of your tests. About the Technology Go is simple to learn, yet hard to master. Even experienced Go developers may end up introducing bugs and inefficiencies into their code. This book accelerates your understanding of Go's quirks, helping you correct mistakes and dodge pitfalls on your path to Go mastery.

With the widespread use of VRML browsers, e.g., as part of the Netscape and Internet Explorer standard distributions, everyone connected to the Internet can directly enter a virtual world without installing a new kind of software. The VRML technology offers the basis for new forms of customer service such as interactive three-dimensional product configuration, spare part ordering, or customer training. Also, this technology can be used for CSCW in intranets.The reader should be familiar with programming languages and computers and, in particular, should know Java or at least an object-oriented programming language. The book not only provides and explains source code, which can be used as a starting point for own implementations, but it also describes the fundamental problems and how currently known solutions work. It discusses a variety of different techniques and trade-offs. Many illustrations help the reader to understand and memorize the underlying principles.