For those with any form of liver disease, this concise, practical guide from a trusted expert will help you take care of your liver and your health. Liver disease is a common cause of morbidity and mortality all over the world-and it's on the rise. Approximately 3.3 million US adults are currently living with hepatitis B or C, 25% of whom will go on to develop cirrhosis, cancer, or liver failure. More than 3 million new cases of fatty liver disease are reported each year in the United States alone, and the prevalence of this condition is increasing rapidly. Alcohol-related liver disease has become a leading cause of preventable death in young people. In Your Complete Guide to Liver Health, world-renowned gastroenterologist and liver specialist Dr. Paul J. Thuluvath reveals how everything from infections to the medications you take to what you eat and drink can affect not only your liver but also your overall health. Dr. Thuluvath teaches you all you need to know about this vital organ, including * how your liver works * how to prevent liver infections and disease * how diseases that affect the liver, including cancer, liver failure, fatty liver, hepatitis, and more, are diagnosed and treated * which foods, drinks, and supplements to avoid * how you can take care of your liver and your health for the rest of your life In each chapter of this comprehensive yet concise book, Dr. Thuluvath explains in easy-to-follow language how the liver is affected by the various conditions covered, along with how each particular disease is diagnosed and treated. Those with a liver disease need to take special care not to cause additional damage to their liver-this book shows you how.

"Histopathology of Seed-Borne Infections is the first book to provide comprehensive coverage of seed infection and disease. It includes an up-to-date account on the development and structure of seed, pointing out the structural variations in seeds of the plant families to which most crop plants belong. The text presents techniques and advice for histopathological studies, as well as a discussion on physiogenic seed disorders and the penetration of ovule/seed by fungi. Featuring an extensive bibliography, this book serves as a springboard for further research in seed biology and provides a literature review in a field where it is difficult to access older sources. It will be a valuable resource for seed and plant scientists, plant pathologists, crop scientists, ecologists, and seed chemists, as well as researchers and students involved in seed and plant pathology, seed technology, and agriculture. Features

Good Drug Regulatory Practices offers a series of policies and procedures to assure quality and timely regulatory submissions to national regulatory agencies. This book begins with introductory chapters describing the need for policy documentation, and the philosophy underlying the policies, and presents policies and standards that can be used as presented or adapted to individual situations in your company.

With this expaned revision of the 1982 classic, The Sugar Trap, Beatrice Trum Hunter, noted writer on food issues, brings readers invaluable help for avoid "the sweetener trap." She exposes facts about today's many sweeteners, from aspartame to stevia, sucralose, and xlitol. With carefl research and well-weighed advice, Hunter explains why it is important to limit all added sugares.

How can new understandings about cancer cell interactions help doctors better control, and eventually cure, cancer? Cancer is a formidable enemy. In fact, people born in America since 1960 face a one in two chance of being diagnosed with cancer in their lifetimes. However, there's growing evidence that fewer cancers will be death sentences for patients. New approaches and understandings are transforming the medical world, increasing success rates for remissions, disease management, and cures. Dr. Ashani Weeraratna is at the forefront of this new level of care. In Is Cancer Inevitable?, Weeraratna-a pioneering melanoma researcher whose work explores the role aging plays in cancer cells' spread and drug resistance-gives readers an inside look at several of the latest cancer advances. Detailing the actions that are reducing the disease's impact and exploring what the future may hold, she explains how the molecular mechanisms involved in metastasis and the cells' microenvironments influence cancer's development and progression. Over the years, she writes, our understanding of how cancer cells move throughout the body, change as they plant themselves in the body's microenvironments, and even communicate with one another have led to major insights about how cancer works. With compelling detail, she takes us inside her lab, revealing how new insights are leading to major breakthroughs, even among patients with Stage IV cancer. She also explains how age-related changes in the microenvironment contribute to multiple aspects of melanoma formation and development. Such scholarship, she argues, is moving us toward a day when more patients will be declared cancer-free. An inspiring and deeply personal book, Is Cancer Inevitable? offers readers newfound hope. Features * Explores key insights and studies developed in recent years that have greatly influenced the world of cancer research, including how aging microenvironments within our bodies encourage metastasis and therapy resistance * Guides readers through Dr. Ashani Weeraratna's personal story of coming to the United States from Lesotho at the age of 17 and rising to become one of the pioneers in her field * Brings readers inside Weeraratna's lab, describing both the processes and the missions of her work * Raises awareness about how cancer works within the body and what any patient or family encountering the disease needs to understand-while also offering them hope based on new and forthcoming diagnostic and treatment methods * Outlines why we will never control-let alone cure-cancer if we don't find a common purpose and come together in collaboration, inviting the greatest minds from around the world to participate in finding and implementing solutions Johns Hopkins Wavelengths In classrooms, field stations, and laboratories in Baltimore and around the world, the Bloomberg Distinguished Professors of Johns Hopkins University are opening the boundaries of our understanding of many of the world's most complex challenges. The Johns Hopkins Wavelengths book series brings readers inside their stories, illustrating how their pioneering discoveries benefit people in their neighborhoods and across the globe in artificial intelligence, cancer research, food systems' environmental impacts, health equity, science diplomacy, and other critical arenas of study. Through these compelling narratives, their insights will spark conversations from dorm rooms to dining rooms to boardrooms.

So far as we are aware, there has never been a book before with this title or aim. This may be because no-one has been foolhardy enough to attempt one! And it is true that this is a story in mid-flow, even perhaps still near the beginning. But the subject is so complex, and surrounded with so many misconceptions that, even in a truncated form, it needs to be told. John Killick has chosen a simple but effective format. Each of the nine main chapters focuses on an individual or individuals (twelve in number) who, in his view, have made significant contributions to our knowledge. The message is one of hope. Although the medical model has yielded little in the way of advances, that is not true of psychosocial initiatives. This little book tells the hidden story of positive approaches, and those who have devoted their lives to finding alternative creative solutions to one of today’s great challenges. If your life is at all touched by dementia, you should be reading it.

How can you lose dramatic weight, reverse chronic conditions, and stay healthier longer? Flip the switch on your metabolism with intermittent fasting, protein restriction, and ketosis! Lose weight. Reverse Chronic Conditions. Live Healthier Longer. Within each of us is an ancient mechanism that eliminates toxic materials, initiates fat burning, and protects cells against stress. It's called autophagy, and when it's turned on, the complex operation can not only slow down the ageing process, but can optimise biological function as a whole, helping to stave off all manner of disease - from diabetes to dementia - and affording us the healthy lifespan we never thought possible. So how can we activate this switch through diet? How frequently should we fast and for how long? Must we abstain from all foods or just specific macronutrients? What's the sweet spot between intermittent fasting, protein restriction, and ketogenic eating? Backed by a wealth of data, and with a practical programme anyone can follow for lasting results, The Switch not only decodes the science of autophagy, but also teaches you how to control it and benefit from its profound impact.

For fans of Oliver Sacks and Henry Marsh, a glimpse into the fascinating world of modern neurology by a leading expert in the field. As a trainee doctor, Andrew Lees was enthralled by his mentors: esteemed neurologists who combined the precision of mathematicians, the scrupulosity of entomologists and the solemnity of undertakers in their diagnoses and treatments. For them, there was no such thing as an unexplained symptom or psychosomatic problem-no difficult cases, only interesting ones-and it was only a matter of time before all disorders of the brain would be understood in terms of anatomical, electrical, and chemical connections. Today, this kind of "holistic neurology" is on the brink of extinction as a slavish adherence to protocols and algorithms-plus a worship of machines-runs the risk of destroying the key foundational clinical skills of listening, observation and imagination that have been at the heart of the discipline for over 150 years. In this series of brilliant, insightful, and autobiographical essays, Andrew Lees takes us on a kind of Sherlock Holmes tour of neurology, giving the reader insight into-and a defense of-the deep analytical tools that the best neurologists still rely on to diagnose patients: to heal minds and to fix brains.

Groundbreaking studies have shown that an absence of certain of microbes in children may be at the root of some of the most prevalent childhood ailments. Written by two experts in the field, this book takes on our oversanitized culture, from pregnancy to birth to early childhood, and explains how we can have a healthier relationship with our microbes.

The handbook that every runner needs on their shelf. Why do I get a headache after a run? Do runners really need to do strength and conditioning? Will running damage my knees? How can I stop my skin chafing on long runs? How quickly will I lose my fitness when I'm off running? What's the best diet for a runner? Run Well answers these and many other common health questions that runners ask. Packed with practical, realistic and sound advice on topics from head to toe, for all of the running community.

An activity book to help caregivers improve the quality of life of people who have dementia. Whether they are cared for at home or in an assisted living community, adults living with dementia should be offered a life that is interesting and fun. But what can you do to enhance the everyday experience of a loved one who is losing interest in or is unable to participate in their old hobbies and pursuits? In Creative Engagement, dementia activity expert Rachael Wonderlin and developmental psychology professor Geri M. Lotze provide dozens of creative, hands-on ways to engage with people living with cognitive loss. Teaching caregivers how to find dementia-friendly daily activities and introduce them into a person's life, this comprehensive, empathetic guide is aimed at both family members and professionals. Twelve chapters full of useful, tangible activities touch on a range of topics, including exercise, technology, cooking and baking, memory games, and arts and crafts. Focusing on both group and individual dynamics, mundane activities and specially tailored pursuits, Wonderlin and Lotze offer proven strategies for interacting with people living with dementia. The authors include detailed tips for building a dementia-friendly environment, creating a daily calendar, and scheduling community entertainment. They also suggest special activities geared toward people in hospice care and give targeted advice for dealing with caregiver stress. Drawing on Wonderlin's own practice while incorporating the latest scientific research on dementia and eldercare, Creative Engagement is unique in its dementia-positive approach. Anyone who cares for someone living with dementia will gain valuable knowledge from this compassionate book.

An NRC Handelsblad Book of the Year "Offers rich discussions of olfactory perception, the conscious and subconscious impacts of smell on behavior and emotion." -Science Decades of cognition research have shown that external stimuli "spark" neural patterns in particular regions of the brain. We think of the brain as a space we can map: here it responds to faces, there it perceives a sensation. But the sense of smell-only recently attracting broader attention in neuroscience-doesn't work this way. So what does the nose tell the brain, and how does the brain understand it? A. S. Barwich turned to experts in neuroscience, psychology, chemistry, and perfumery in an effort to understand the mechanics and meaning of odors. She discovered that scents are often fickle, and do not line up with well-defined neural regions. Upending existing theories of perception, Smellosophy offers a new model for understanding how the brain senses and processes odors. "A beguiling analysis of olfactory experience that is fast becoming a core reference work in the field." -Irish Times "Lively, authoritative...Aims to rehabilitate smell's neglected and marginalized status." -Wall Street Journal "This is a special book...It teaches readers a lot about olfaction. It teaches us even more about what philosophy can be." -Times Literary Supplement

Cutting-edge sleep advice and a 10-day reset plan from a renowned functional medicine physician and co-founder of the popular sleep company Casper.

If you are like most people, the odds are you aren't getting enough sleep. Thanks to shifts in our culture, we are in the midst of an epidemic of sleeplessness, and unfortunately, sleep deprivation has bigger consequences than one might think, ranging from irritability, brain fog, and weight gain to serious conditions like hormone dysregulation, heart disease, memory impairment, diabetes, and Alzheimer's disease.

Better Sleep, Better You offers a one-stop resource to help you reap the benefits of sleeping well every night. Unlike the dozens of blogs and listicles offering a "quick fix" for insomnia, Lipman and Parikh understand that there's no such thing as a one-sleep-fits-all solution. By clearly explaining the latest developments in sleep science and all the factors that affect your sleep – including when and how you eat and exercise, how you handle stress, how you nap, and how you engage with technology – Better Sleep, Better You helps you create a personalised sleep plan, including a ten-day reset that you can put into practice to work for your lifestyle and needs.

Packed with fascinating science, engaging case studies, and easy-to-implement practical advice, this book provides everything you need to optimize your sleep, productivity, and happiness – for life.

"The medical establishment has become a major threat to health." This is the opening statement and basic contention of Ivan Illich's searing social critique. In "Limits to Medicine" Ivan Illich has enlarged on this theme of disabling social services, schools, and transport, which have become, through over-industrialization, harmful to man. In this radical contribution to social thinking Illich decimates the myth of the magic of the medical profession.

"Regaining the Power of Youth at Any Age" features a scientifically based program that will guide you to a higher level of physical and mental fitness that you may have believed impossible to attain.

From patient advocate and author of Living Well with Hypothyroidism Mary J. Shomon, here is a holistic roadmap for diagnosis, treatment and recovery for the millions of people suffering from Graves' disease and hyperthyroidism.

There are an estimated 3 million-plus Americans suffering from Graves' disease and hyperthyroidism, and patient advocate Mary J. Shomon will guide them through the diagnosis and the wide-ranging treatments available. Graves' disease and hyperthyroidism are the result of the thyroid gland being overactive. This gland controls the body's metabolism, so people afflicted with the disorder can suffer from symptoms such as significant weight loss, fatigue, muscular weakness, and rapid heartbeat, among others. In addition to conventional treatments, this resource uniquely highlights holistic treatments, and through case studies and testimonials from patients and doctors, presents an honest look at the lifestyles and choices of people living with these conditions.

Shomon presents the reader with a comprehensive resource that spans from diagnosis to treatment to life after treatment. She goes beyond the conventional advice of other books, utilizing patient anecdotes and, as a fellow thyroid disease patient, her own experience. Her extensive network of experts--from conventional physicians to alternative practitioners--allows for a wide range of treatment options. In addition, a comprehensive Appendix serves as a fantastic resource for patients seeking treatment and additional advice.

The first edition of Living Well With Hypothyroidism (2/2000) started with a first printing of 7,500 copies and has now sold over 100,000 in the US. Shomon's The Thyroid Diet hit the New York Times extended bestseller list.

Mary Shomon has been praised by doctors around the country for her medical knowledge and sensitivity to patients' needs.

Barbara Bush brought attention to the plight of Graves' disease patients, announcing that she was suffering from it when she was First Lady.

The #1 New York Times best-selling author and beloved healing authority reveals how taking your liver off overload can help resolve a wide range of symptoms and conditions--and transform your health in ways you've never imagined.

What if you could focus on one aspect of your well-being to transform all the others--and at the same time prevent health problems you didn't even know were lurking beneath the surface?

In today's world, we have no idea how many symptoms, conditions, and diseases are rooted in an overloaded liver. It's not only about liver cancer, cirrhosis, and hepatitis. Nearly every challenge--from pesky general health complaints to digestive issues to emotional struggles to weight gain to high blood pressure to heart problems to brain fog to skin conditions to autoimmune and other chronic illnesses--has an origin in an overloaded liver and can improve and heal when you harness the force of this humble organ.

Medical Medium Liver Rescue offers the answers you should have had all along. With his signature compassion, Anthony William, the Medical Medium, shares unparalleled insights into undiscovered functions of our life-saving livers, explains what's behind dozens of health issues that hold us back, and offers detailed guidance on how to move forward so we can live our best lives. Find out for yourself what liver rescue is all about: being clearer-headed, more peaceful, happier, and better able to adapt to our fast-changing times. Learn how to sleep well, balance blood sugar, lower blood pressure, lose weight, and look and feel younger. A healthy liver is the ultimate de-stressor, anti-aging ally, and safeguard against a threatening world--if we give it the right support.

A cutting-edge yet practical guide for newly-diagnosed and established type 2 diabetes patients and their families, providing an understanding of what really causes the condition and therefore how to manage it effectively, by one of the UK's leading diabetes physicians. The book includes much that will be unfamiliar to non-specialist doctors, helping sufferers to manage their own condition better and work optimally with healthcare professionals: The primary problem is not blood glucose but fat in the wrong organs (liver and pancreas); Type 1 diabetes can masquerade as type 2 - the warning signs; Putting the Newcastle-type ultra-low-calorie diet into real life use; Managing cholesterol and blood pressure problems; Reasonable blood sugar levels and minimising medication; Overcoming complications; Questions patients should be asking

'Inspiring' GUARDIAN 'Heartbreaking' INDEPENDENT 'I loved it' ADAM KAY 'Beautiful' MATT HAIG 'Luminous' NICCI GERRARD 'Essential reading' MADELEINE BUNTING 'A celebration' CHRISTIE WATSON ----- A Best Book for Summer in The Times, Guardian and The i Independent Book of the Month ----- Caring is an issue that affects us all - as bestselling novelist Kate Mosse knows all too well. Kate has cared in turn for her father and mother, and for Granny Rosie, her 90-year-old mother-in-law. Along the way she has experienced the joys, challenges and frustrations shared by an invisible army of carers. At the heart of this care lie everyday acts of love, and the realisation that, sooner or later, most of us will come to rely on an extra pair of hands. ----- 'Lifts the spirits without pulling punches' IAN RANKIN 'Irresistible' RACHEL JOYCE 'Questions how and why we fetishise independence when the reality of human experience is always interdependence' GUARDIAN, BOOK OF THE DAY 'Heartfelt, funny and at times heartbreaking. 10/10' INDEPENDENT 'Utterly beautiful' FRANCESCA SEGAL