The overall scope of this new series will be to evolve an understanding of the genetic basis of (1) how early mesoderm commits to cells of a heart lineage that progressively and irreversibly assemble into a segmented, primary heart tube that can be remodeled into a four-chambered organ, and (2) how blood vessels are derived and assembled both in the heart and in the body. Our central aim is to establish a four-dimensional, spatiotemporal foundation for the heart and blood vessels that can be genetically dissected for function and mechanism. Since Robert DeHaan's seminal chapter "Morphogenesis of the Vertebrate Heart" published in Organogenesis (Holt Rinehart & Winston, NY) in 1965, there have been surprisingly few books devoted to the subject of cardiovascular morpho genesis, despite the enormous growth of interest that occurred nationally and inter nationally. Most writings on the subject have been scholarly compilations of the proceedings of major national or international symposia or multi authored volumes, without a specific theme. What is missing are the unifying concepts that can often make sense out of a burgeoning database of facts. The Editorial Board of this new series believes the time has come for a book series dedicated to cardiovascular mor not only as an important archival and didactic reference phogenesis that will serve source for those who have recently come into the field but also as a guide to the evo lution of a field that is clearly coming of age.

This book uniquely explores American cultural values as a factor in maternal health. It looks beyond the social determinants of health as primarily contributing to the escalating maternal morbidity and mortality in the United States.    The United States is an outlier with poor maternal health outcomes and high morbidity/mortality in comparison to other high-resource and many mid-level resource nations. While the social determinants of health identify social and environmental conditions affecting maternal health, they do not answer the broader underlying question of why many American women, in a high-resource environment, experience poor maternal health outcomes. Frequent near-misses, high levels of severe childbearing-related morbidity, and high maternal mortality are comparable to those of lower-resource nations.  This book includes contributions from recognized medical and cultural anthropologists, and diverse clinical and public health professionals. The authors examine American patterns of decision-making from the perspectives of intersecting social, cultural, and medical values influencing maternal health outcomes. Using an interdisciplinary critical analysis approach, the work draws upon decision-making theory and life course theory. Topics explored include: Cultural values as a basis for decision-making Social regard for motherhood Immigrants, refugees and undocumented mothers Cultural conflicts and maternal autonomy Health outcomes among justice-involved mothers Maternal Health and American Cultural Values: Beyond the Social Determinants is an essential resource for clinical and public health practitioners and their students, providing a framework for graduate-level courses in public health, the health sciences, women’s studies, and the social sciences. The book also targets anthropologists, sociologists, and women studies scholars seeking to explain the links between American cultural decision-making and health outcomes. Policy-makers, ethicists, journalists, and advocates for reproductive health justice also would find the text a useful resource.

Birth controlled analyses the world of selective reproduction - the politics of who gets to legitimately reproduce the future - through a cross-cultural analysis of three modes of 'controlling' birth: contraception, reproductive violence and repro-genetic technologies. It argues that as fertility rates decline worldwide, the fervour to control fertility, and fertile bodies, does not dissipate; what evolves is the preferred mode of control. Although new technologies like those that assist conception or allow genetic selection may appear to be an antithesis of other violent versions of population control, this book demonstrates that both are part of the same continuum. All population control policies target and vilify women (Black women in particular), and coerce them into subjecting their bodies to state and medical surveillance; Birth controlled argues that assisted reproductive technologies and repro-genetic technologies employ a similar and stratified burden of blame and responsibility based on gender, race, class and caste. To empirically and historically ground the analysis, the book includes contributions from two postcolonial nations, South Africa and India, examining interactions between the history of colonialism and the economics of neoliberal markets and their influence on the technologies and politics of selective reproduction. The book provides a critical, interdisciplinary and cutting-edge dialogue around the interconnected issues that shape reproductive politics in an ostensibly 'post-population control' era. The contributions draw on a breadth of disciplines ranging from gender studies, sociology, medical anthropology, politics and science and technology studies to theology, public health and epidemiology, facilitating an interdisciplinary dialogue around the interconnected modes of controlling birth and practices of neo-eugenics. -- .

Male Reproductive Function gives an up-to-date review on the physiology and disease processes associated with the male reproductive system. The first few chapters describe the regulation of the functions of the testis and the integration of its components: germ cells, Sertoli cells and Leydig cells. This is followed by a description of puberty and aging, and the disorders or dysfunction that may be associated with these physiological processes. Discussions on the current methods for the diagnosis and treatment of male hypogonadism, male infertility and male sexual dysfunction follow, with detailed descriptions of types of androgen replacement and the benefits and risks of such treatment. The book concludes with the development of male contraception and the possible influence of the environment on the male reproductive system. Male Reproductive Function represents a conglomeration of the efforts of experts in andrology from all over the world, both in basic cellular/molecular biology as well as in clinical science and practice. This book is suitable for endocrinologists, urologists, general internists, gynecologists and other students in the field of male reproduction.

Drawing on never before used archival materials, Replacing the Dead exposes the history of Soviet and Russian abortion policy. It is not unusual for nations recovering from wars to incentivize their populations to raise their birthrates. The post-World War II Soviet pronatalism campaign attempted this on an unprecedented scale, aiming to replace a lost population of 27 million. Why, then, did the USSR re-legalize abortion in 1955? Mie Nakachi uses previously hidden archival data to reveal that decisions made by Stalin and Khruschev under the rubric of 'family law' created a society of broken marriages, "fatherless" children, and abortions, each totaling in the tens of millions. The government reversed laws regarding paternal responsibility, thereby encouraging men to impregnate unmarried women and widows, and blocked available contraception, overriding the advice of the medical establishment. Some 8.7 million out-of-wedlock children were born between 1945 and 1955 alone. In the absence of serious commitment to supporting Soviet women who worked full-time, the policy did extensive damage to gender relations and the welfare of women and children. Women, famous cultural figures, and Soviet professionals initiated a movement to improve women's reproductive health and make all children equal. Because Soviet leaders did not allow any major reform, an abortion culture grew among Soviet women and spread throughout the Soviet sphere, including Eastern Europe and China. Based on groundbreaking research, Replacing the Dead traces how the idea of women's right to an abortion emerged from an authoritarian society decades before it did in the West and why it remains the dominant method of birth control in present-day Russia.

Volume Two advances the exploration of the fundamental principles of oxidative stress and toxicity on male (and female) reproduction. It includes the advances in research on male reproductive health, the impact of environmental factors, the protective measures using bioactive compounds and traditional medicines, and how to limit toxic exposure. It includes coverage of: Oxidative stress and male infertility Environmental stressors and sexual health Heavy metals, pesticides, fine particle toxicity and male reproduction Protective measures against oxidative stress in gametes/embryos by using bioactive compounds/phytomedicines in Assisted Reproductive Technology (ART) Role of reactive oxygen species on female reproduction Radiation and mutagenic factors affecting the male reproductive system Both volumes provide a comprehensive look at the most basic concepts and advanced research being conducted by world famous scientists and researchers in male infertility and reproduction.

This book discusses many aspects of fetuses and motherhood from fields as wide as sociology and medicine. It examines changing perceptions of the fetus over recent decades, comparing western ideas with those of non-western countries; examining maternal mental health during COVID-19 and charting the ascent of the 'fetus' to a cult phenomenon, which has currently reappeared in the courts. This work, given its multifaceted approach, will be of interest to a varied and wide range of people, from parents to doctors and nurses, to anthropologists and ethnologists, to scientists, to students of various disciplines, to psychologists and psychoanalysts, to lawyers dealing with the topic and to a general public simply interested in these fundamental themes.

These proceedings of the 2018 XIII International Symposium on Spermatology focus on comparative biology, and encourages discussion and the exchange of ideas. The aim of this Symposium was to provide a unique opportunity and bring together scientists from a wide spectrum of research fields - human, domestic animals and other mammals, vertebrates, insects, and plants. The underlying focus is on the function of the spermatozoon - a common feature for sexual reproduction, but extremely varied. By exploring the variability, a better understanding of male reproductive functions can develop. These proceedings address the mechanisms of physiology and pathophysiology, rather than diagnosis and treatment. The symposium featured keynote lectures by invited speakers, followed by presentations on specific aspects of the general topic of the session. Experimental studies are given priority over clinical studies of patient populations. The proceedings comprise both keynote speakers' texts and selected free communications. Posters were considered for publication in the proceedings, and the volume includes exhibited materials on the work of prominent spermatologists, highlighting their important past achievements in the field.

Gain a foundational understanding of how endocrine and metabolic physiology affects other body systems in health and disease, including the clinical dimensions of reproductive endocrinology. Endocrine and Reproductive Physiology, a volume in the Mosby Physiology Series, explains the fundamentals of this complex subject in a clear and concise manner, while helping you bridge the gap between normal function and disease with pathophysiology content throughout the book. Helps you easily master the material in a systems-based curriculum with learning objectives, Clinical Concept boxes, highlighted key words and concepts, chapter summaries, self-study questions, and a comprehensive exam. Includes nearly 200 clear, 2-color diagrams that simplify complex concepts. Features clinical commentaries that show you how to apply what you've learned to real-life clinical situations. Keeps you current with recent advances in endocrine physiology with expanded material on reproductive endocrinology and metabolism, and many updates at the molecular and cellular level. Covers the latest developments in fertilization, pregnancy, and lactation, as well as fetal development, puberty, and the decline of reproductive function with age. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices. Complete the Mosby Physiology Series! Systems-based and portable, these titles are ideal for integrated programs. Blaustein, Kao, & Matteson: Cellular Physiology and Neurophysiology Johnson: Gastrointestinal Physiology Koeppen & Stanton: Renal Physiology Cloutier: Respiratory Physiology Pappano & Weir: Cardiovascular Physiology Hudnall: Hematology: A Pathophysiologic Approach

This new edition provides an update on the molecular mechanisms that regulate spermatogenesis. In addition to the rodent as a study model, chapters also include research on studies in humans. It includes the latest approaches of studying spermatogenesis, such as the use of bioinformatics, molecular modeling and others which are not commonly found in published materials. It also reviews the latest developments in the field, such as studies on the role of regulatory RNAs on spermatogenesis. Due to the declining fertility rate among men, a brand new chapter highlights the impact of environmental toxicants on spermatogenesis.

Women most fully experience the consequences of human reproductive technologies. Men who convene to evaluate such technologies discuss "them": the women who must accept, avoid, or even resist these technologies; the women who consume technologies they did not devise; the women who are the objects of policies made by men. So often the input of women is neither sought nor listened to. The privileged insights and perspectives that women bring to the consideration of technologies in human reproduction are the subject of these volumes, which constitute the revised and edited record of a Workshop on "Ethical Issues in Human Reproduction Technology: Analysis by Women" (EIRTAW), held in June, 1979, at Hampshire College in Amherst, Massachusetts. Some 80 members of the workshop, 90 percent of them women (from 24 states), represented diverse occupations and personal histories, different races and classes, varied political commitments. They included doctors, nurses, and scientists, lay midwives, consumer advocates, historians, and sociologists, lawyers, policy analysts, and ethicists. Each session, however, made plain that ethics is an everyday concern for women in general, as well as an academic profession for some.

At last, a comprehensive collection of essays that examines and advances ethical evaluations of the controversial and increasingly popular practice of embryo adoption. In the United States alone, 400,000 frozen embryos created for in vitro fertilization exist but are no longer desired for that purpose. What are we morally obliged or permitted to do about these a oesparea embryos? More of their genetic parents are considering donating these embryos to others to gestate and raise. This practice is politically volatile (figuring in debates about embryonic stem cells) and medically and morally complex. At the present time within the Roman Catholic Church there is no official teaching on embryo adoption. Catholic ethical analyses grapple with the way embryo adoption comports with respect for embryonic human life yet challenges Catholic moral critiques of assisted reproductive technologies.

This volume is the first to bring together leading philosophers and theologians to engage Catholic debates about embryo adoption in an interactive format. The editors, a philosopher bioethicist and a moral theologian, provide a helpful overview of the practice and the arguments surrounding embryo adoption. They engage neglected Catholic ethical resources and issues to advance the current debate and chart new directions in Catholic moral thinking about this intriguing practice. The volume also includes a description of embryo adoption from a physician practitioner along with reflections from a couple who successfully adopted an embryo.

This book offers a vision of politics that govern the womb; from antiquity ('be fertile and replenish the earth'), through the ages (hysterectomy, to extirpate women's 'hysteria'), up to the present time (abortion wars; assisted reproduction), and into the future (reprogenetics; the artificial womb). It explores how the womb has served humanity, either tacitly or explicitly, through the ages and examines how women have accepted and still perceive the rules created by men as natural - including the new anti-abortion laws in the USA - because 'that is the way things are.' The book also explores how the emerging of assisted reproduction technologies and novel genetic tools (reprogenetics) will pose additional challenges to womb bearers, as all women will be made to reproduce with IVF. What is more, the advent of the artificial womb is in sight; the gender and social implications of this development would be enormous. Certainly not just another organ, the womb has been and remains a powerful tool that cannot be left to the decisions of half of the population. This book engages a wide audience, including women and men, professionals and laypersons who are interested in gender, politics, legislation, women's health, and ethics.

Women most fully experience the consequences of human reproductive technologies. Men who convene to evaluate such technologies discuss Itthem ": the women who must accept, avoid, or even resist these technologies; the women who consume technologies they did not devise; the women who are the objects of policies made by of women is neither sought nor listened to. The men. So often the input and perspectives that women bring to the privileged insights consideration of technologies in human reproduction are the subject of these volumes, which constitute the revised and edited record of a Workshop on "Ethical Issues in Human Reproduction Technology: Analysis by W omen" (EIR TAW), held in June, 1979, at Hampshire College in Amherst, Massachusetts. Some 80 members of the workshop, 90 percent of them women (from 24 states), represented diverse occupations and personal histories, different races and classes, varied political commitments. They included doctors, nurses, and scientists, lay midwives, consumer advocates, historians, and sociologists, lawyers, policy analysts, and ethicists. Each session, however, made plain that ethics is an everyday concern for women in general, as well as an academic profession for some.

Part of the renowned Donald School series, this book is a comprehensive guide to the diagnosis and management of reproductive and gynaecological endocrinology disorders. The book begins with an overview of ovulation and investigation and causes of female infertility including anovulation, tubal block, endometriosis and congenital uterine anomalies. The following chapters discuss ovarian stimulation and assisted reproductive techniques. The second half of the book covers causes and management of male infertility, and concludes with chapters on recurrent miscarriage, gamete banking, and assessment of early pregnancy. Authored by recognised experts in the field, the text is further enhanced by clinical photographs, illustrations, tables and flowcharts. Key points Comprehensive guide to diagnosis and management of reproductive and gynaecological endocrinology disorders Part of renowned Donald School series Covers investigation, causes and management of both female and male infertility Authored by recognised experts in the field

Obesity is a continuing issue around the world and in many contexts. The growing number of obese people is an increasing concern for those in the medical profession, and obesity can pose specific challenges in relation to fertility and pregnancy. Patients who are obese require specific considerations and knowledge. Bringing together experts from a variety of specialties to examine the issues and challenges of obesity, this book discusses how obesity affects fertility, reproduction, and pregnancy. Beginning with an exploration of the epidemiology of obesity, further chapters focus on specific issues related to obesity and both male and female reproduction, the complications of obesity during pregnancy and labour, and the long term effects of obesity. This is the most comprehensive resource to examine the topic of obesity and reproductive issues, making it invaluable for medical students, professionals, and researchers in public policy and medicine.
Comprehensive examination of fertility issues arising from male and female obesityClinical knowledge and expertise given to the subjectsIn-depth examination through 47 chapters of a growing, but often overlooked, issue in fertility and pregnancy

This book provides a resource of current understandings about various aspects of the biology of spermatogonia in mammals. Considering that covering the entire gamut of all things spermatogonia is a difficult task, specific topics were selected to provide foundational information that will be useful for seasoned researchers in the field of germ cell biology as well as investigators entering the area. Looking to the future, the editors predict that the foundational information provided in this book -- combined with the advent of new tools and budding interests in use of non-rodent mammalian models -- will produce another major advance in knowledge regarding the biology of spermatogonia over the next decade. In particular, we anticipate that the core molecular machinery driving different spermatogonial states in most, if not all, mammals will be described fully, the extrinsic signals emanating from somatic support cell populations to influence spermatogonial functions will become fully known, and the capacity to derive long-term cultures of SSCs and transplant the population to regenerate spermatogenesis and fertility will become a reality for higher order mammals.

Reproductive and Developmental Toxicology, Third Edition is a comprehensive and authoritative resource, providing the latest literature on this complex subject by focusing on three core components - parent, placenta and fetus - and the continuous changes that occur in each. Enriched with relevant references describing every aspect of reproductive toxicology, this revised and updated resource addresses the totality of the subject, discussing a broad range of topics including nanoparticles and radiation, gases and solvents, smoking, alcohol and drugs of abuse, and metals, among others. In addition, it is the only resource to include reproductive and developmental toxicity in domestic animals, fish and wildlife With a special focus on placental toxicity, this book is the only available reference to connect the three key risk stages. Completely revised and updated to include the most recent developments in the field, this book is an essential resource for advanced students and researchers in toxicology, as well as biologists, pharmacologists and teratologists from academia, industry and regulatory agencies.

Diverse Pathways to Parenthood: From Narratives to Practice is a timely contribution to the study of reproduction and parenthood. Drawing on a wide breadth of projects, this book covers topics such as first time parents, donor conception, pregnancy loss, surrogacy, lesbian, gay and/or transgender parenting, fostering and adoption, grandparenting, and human/animal kinship. By presenting individual narratives focused on reproduction and parenthood, this book successfully translates empirical research into practical, applied outcomes that will be of use for all those working in the fields of reproduction and parenthood. Including recommendations for fertility specialists, educators, child protection agencies, reproductive counselors, and policy makers, Diverse Pathways to Parenthood: From Narratives to Practice is a vital new resource that will help guide practice into the future. As a contribution to the field of critical kinship studies, this book heralds new directions for the study of kinship, by revisiting as well as reimagining how we think about, research, and respond to a diversity of kinship forms.

Human Reproductive Genetics: Emerging Technologies and Clinical Applications presents a great reference for clinicians and researchers in reproductive medicine. Part I includes a brief background of genetics and epigenetics, probability of disease, and the different techniques that are being used today for analysis and genetic counseling. Part II focuses on the analysis of the embryo, current controversies and future concepts. Part III comprises different clinical scenarios that clinicians frequently face in practice. The increasing amount of genetic tests available and the growing information that patients handle makes this section a relevant part of the fertility treatment discussion. Finally, Part IV concludes with the psychological aspects of genetic counseling and the role of counselor and bioethics in human reproduction.

This volume comprehensively focuses on polycystic ovary, metabolic syndrome and obesity and their impact on women's health, reproduction and quality of life from adolescence to old age. PCOS is analyzed form the early origins - highlighting the importance of diagnosis, management and treatment starting from the high-risk period of adolescence - throughout infertility PCOS-related issues, pregnancy and menopause transition. All aspects of this syndrome are covered also in relation with endocrine and metabolic features that affects women's health. This book is a very useful tool for gynecologists, endocrinologists, obstetricians, reproductive medicine and general practitioners and is an important resource for all physicians involved in women's health.

Sex matters! Are there differences between the sexes when it comes to brain function and the behaviours that result? This volume attempts to answer this fundamental question. If the answer is 'yes' then this should impact upon our approach to treating mental illness in humans, and to modelling it in animals, as we look for aetiological and pharmacological solutions.