Assisted Reproduction is a specialty undergoing rapid change as new technologies are introduced and new research challenges previous treatment options. This text examines a selection of controversial topics for both laboratory and clinical practice and tries to place them in perspective, so readers can understand how and why the current state of the question has come about and how future contributions to the debate should be measured. All physicians involved with the technologies concerned will learn from the expert contributions assembled here. CONTENTS: The use of ovarian markers * Use of molecular markers of endometrial receptivity * Use of GnRHa for triggering final oocyte maturation during ovarian stimulation cycles * Use of time-lapse embryo imaging in assisted reproductive technology practice * Use of cryopreservation for all embryos * Preimplantation genetic screening * The use of single embryo transfer * Use of luteal phase support * Measuring safety and efficiency in in vitro fertilization * To flush follicles during egg collection or not * Use of blastocyst culture * Use of mitochondrial donation * Controversies in recurrent implantation failure: From theory to practice * Fibroids: To remove or not? * Limitations of endometrioma surgery in in vitro fertilization: Possibilities of early disease control

Fully revised for this fourth edition, the Oxford Handbook of Obstetrics and Gynaecology fully reflects new developments in the field. Featuring new sections on the outcomes of the MBRRACE report, abnormally adherent and invasive placenta, pregnancies in mothers of advanced age, assisted reproduction, and ovarian cancer screening, it provides a contemporary overview of this complex and important specialty. Written and reviewed by a team of highly experienced clinicians, academics, and trainees, this Handbook is a perfect starting point for preparation for postgraduate exams. Practical advice is presented with key evidence-based guidelines, supported by visual algorithms and top clinical tips. The previous edition was Highly Commended in the Obstetrics and Gynaecology category of the BMA Book Awards. The indispensable, concise, and practical guide to all aspects of obstetric and gynaecological medical care, diagnosis, and management, this fourth edition continues to be the must-have resource for all specialist trainees, junior doctors, and students, as well as a valuable aide memoire for experienced clinicians.

In recent years increasing numbers of women from wealthy countries have turned to egg donation, egg freezing, and in vitro fertilization to become pregnant, especially later in life. This trend has created new ways of using, exchanging, and understanding oocytes-the reproductive cells specific to women. In The Oocyte Economy Catherine Waldby draws on 130 interviews---with scientists, clinicians, and women who have either donated or frozen their oocytes or received those of another woman---to trace how the history of human oocytes' perceived value intersects with the biological and social life of women. Demonstrating how oocytes have come to be understood as discrete and scarce biomedical objects open to valuation, management, and exchange, Waldby examines the global market for oocytes and the power dynamics between recipients and the often younger and poorer donors. With this exploration of the oocyte economy and its contemporary biopolitical significance, Waldby rethinks the relationship between fertility, gendered experience, and biomedical innovation.

Shortlisted for the Foundation for the Sociology of Health and Illness Book Prize 2021 The ebook edition of this title is Open Access, thanks to Knowledge Unlatched funding, and freely available to read online. Growing numbers of women around the world are now accessing social egg freezing: a fertility extension technology which is enabling some women to extend their fertility and reproductive timelines when faced with age-related fertility decline. This book explores the accounts and experiences of some of the pioneering users of this technology in the UK and the USA. Drawing on theories and concepts across medical sociology and parenting culture studies, as well as literature from demography, anthropology, law, and bioethics, this book examines women's motivations and experiences of social egg freezing in the context of debates surrounding reproductive choice and delayed motherhood. The book also delves into the broader sociological questions raised by this technology in relation to the gendered burden of appropriately timed parenthood, the medicalisation of women's bodies in the reproductive domain and the further entrenchment of the geneticisation of society. It also considers the sexual politics underpinning the timing of parenthood, relationship formation and progression, and the way in which reproductive and parenting ideals, values and expectations can come in to conflict with the biological and relational realities of women's lives.

'Thoughtful, tense and affecting' Ashley Audrain This tense and emotional novel follows the fallout after two women's eggs are switched during IVF. ___________ TWO WOMEN. ONE BABY. A FIGHT LIKE NO OTHER. Katherine has everything under control. After years of struggling to conceive with her partner, Patrick, she finally gives birth to Rose, her IVF miracle child. But she's afraid that Rose may not be her daughter, her pale skin not matching Katherine's own. Tess never got her happy ending. Just like Katherine, she was also a hopeful IVF mother, but her daughter, Hanna, was stillborn. Now divorced, broke and stuck in a dead-end job, she's beginning to lose all hope. But when Rose is ten months old, both women get a call from the fertility clinic. There was a mistake: their eggs were switched. It will take a custody battle like no other to decide who will get to be Rose's mother - a battle that will push them both to the brink... This is a story about what it means to be a mother, and the lengths we go to for the people we love. ___________ 'Thoughtful, tense and affecting' Ashley Audrain, Sunday Times bestselling author of The Push 'An absorbing and engaging novel that twists the heart' Rachel Hore, Sunday Times bestselling author of A Beautiful Spy 'Breathtakingly taut, unflinching and poignant' Marissa Stapley, New York Times bestselling author of LUCKY 'Compelling and thought-provoking ... A page-turner' Charmaine Wilkerson, New York Times bestselling author of Black Cake 'A tender exploration of secrets, loss, and motherhood' Lola Akinmade Akerstroem, international bestselling author of In Every Mirror She's Black 'A future classic' Leah Hazard, Sunday Times bestselling author of Hard Pushed: A Midwife's Story 'Will break your heart' Julie Ma, author of Richard and Judy selected debut Happy Families

Fertility Awareness is key to understanding sexual and reproductive health at all life stages. It can be used to either plan or avoid pregnancy. Fertility Awareness Methods (FAMs) are highly effective when motivated couples are taught by trained practitioners. These methods are in demand for ecological, medical, cultural, religious and moral reasons. The ability to control fertility naturally is a lifestyle choice. The Complete Guide to Fertility Awareness provides the science and methodology suitable for health professionals and a general audience. It covers reproductive physiology and the fertility indicators: temperature, cervical secretions and cycle length calculations. It explores ways to optimise conception and to manage conception delays. Case studies and self-assessment exercises are included throughout. The book addresses the scientific credibility of new technologies including fertility apps, home test kits, monitors and devices. The Complete Guide to Fertility Awareness offers: evidence-based information for general practitioners, practice nurses, school nurses, midwives, sexual health doctors and nurses a unique perspective on subfertility for gynaecologists and fertility nurses an authoritative source of reference for medical, nursing and midwifery students a straightforward and practical reference for new and experienced FAM users the core text for the FertilityUK Advanced Skills Course in Fertility Awareness

The most common abnormal growth of the female reproductive system, fibroids, are thought to affect the majority of women at some point during their reproductive years. This text from leading fibroid experts looks at the latest evidence on how the problem impinges on reproduction and the most up-to-date management and treatment options available to help patients with fibroids hoping to conceive. Print versions of this book also include access to the eBook version with links to procedural videos.

Mammalian Endocrinology and Male Reproductive Biology provides comprehensive and current coverage of the area of endocrinology and male reproductive biology, covering not just humans, but mammals in general. Written by international experts in their respective fields, this multi-author book also covers the latest developments in genomics of androgen action and male infertility. The book begins by covering sexual dimorphism in the central nervous system; structure, control of secretion and function of GnRH; and gonadotropins of pituitary origin and their role in gonadal functions. This is followed by an account of hormonal regulation of spermatogenesis, and the role of apoptosis in this process. Subsequent chapters center around epididymis, regulation of growth and function, and sperm motility regulation. The last chapters in the book discuss the structure and function of male accessory sex glands with associated pathologies as well as recent updates in male contraception, mechanism of androgen action, and genomics of male infertility. Wherever necessary, tables and figures have been added for a better understanding. Each chapter is appropriately referenced and contains current information on the latest developments in the field.

Although there are far more opportunities for LGBTQ people to become parents than there were before the 1990s, attention to the reproductive challenges LGBTQ families face has not kept pace. Reproductive Losses considers LGBTQ people's experiences with miscarriage, stillbirth, failed adoptions, infertility, and sterility. Drawing on Craven's training as a feminist anthropologist and her experiences as a queer parent who has experienced loss, Reproductive Losses includes detailed stories drawn from over fifty interviews with LGBTQ people (including those who carried pregnancies, non-gestational and adoptive parents, and families from a broad range of racial/ethnic, socio-economic, and religious backgrounds) to consider how they experience loss, grief, and mourning. The book includes productive suggestions and personal narratives of resiliency, commemorative strategies, and communal support, while also acknowledging the adversity many LGBTQ people face as they attempt to form families and the heteronormativity of support resources for those who have experienced reproductive loss. This is essential reading for scholars and professionals interested in LGBTQ health and family, and for individuals in LGBTQ communities who have experienced loss and those who support them. See additional material on the companion website: www.lgbtqreproductiveloss.org/

Offers an expert blend of sound theory and evidence based therapy for residents and practitioners. Provides a clear path through the increasing complexity of ART options and techniques, using clinical experience and common practical sense. Condenses the aspects of knowledge and practice most relevant for learning the practical basics of diagnosis and decision making.

The comprehensive and authoritative guide to clinical reproductive science The field of clinical reproductive science continues to evolve; this important resource offers the basics of reproductive biology as well as the most recent advance in clinical embryology. The author - a noted expert in the field - focuses on the discipline and covers all aspects of this field. The text explores causes of male and female infertility and includes information on patient consultation and assessment, gamete retrieval and preparation, embryo culture, embryo transfer and cryopreservation. Comprehensive in scope, the text contains an introduction to the field of clinical reproductive science and a review of assisted reproductive technology. The author includes information on a wide range of topics such as gonadal development, the regulation of meiotic cell cycle, the biology of sperm and spermatogenesis, in vitro culture, embryo transfer techniques, fundamentals of fertilisation, oocyte activation and much more. This important resource: Offers an accessible guide to the most current research and techniques to the science of clinical reproduction Covers the fundamental elements of reproductive science Includes information on male and the female reproductive basics - everything from sexual differentiation to foetal development and parturition Explores the long-term health of children conceived through IVF Contains the newest developments in assisted reproductive technology Clinical Reproductive Science is a valuable reference written for professionals in academia, research and clinical professionals working in the field of reproductive science, clinical embryology and reproductive medicine.

Since the late nineteenth century, medicine has sought to foster the birth of healthy children by attending to the bodies of pregnant women, through what we have come to call prenatal care. Women, and not their unborn children, were the initial focus of that medical attention, but prenatal diagnosis in its present form, which couples scrutiny of the fetus with the option to terminate pregnancy, came into being in the early 1970s. Tangled Diagnoses examines the multiple consequences of the widespread diffusion of this medical innovation. Prenatal testing, Ilana Löwy argues, has become mainly a risk-management technology—the goal of which is to prevent inborn impairments, ideally through the development of efficient therapies but in practice mainly through the prevention of the birth of children with such impairments. Using scholarship, interviews, and direct observation in France and Brazil of two groups of professionals who play an especially important role in the production of knowledge about fetal development—fetopathologists and clinical geneticists—to expose the real-life dilemmas prenatal testing creates, this book will be of interest to anyone concerned with the sociopolitical conditions of biomedical innovation, the politics of women’s bodies, disability, and the ethics of modern medicine.

This comprehensive volume focuses on recent trends and new technologies used in the management of reproduction in major farm animals, focusing on both males and females of bovine, equine, and porcine species. With chapters written by scientists who specialize in their respective topics, the volume presents a selection of different technologies that have been developed to assure reproductive success by improving reproductive efficiency, generating germplasm banks, and maintaining genetic diversity in cattle, horses, and pigs. In the last decade, reproductive technologies in veterinary medicine have progressed considerably, providing high profitability to livestock farms. This book provides basic and applied information on the most used reproductive technologies in bovine, equine, and porcine species for academics, scientists, and veterinarians. The volume discusses reproductive and postpartum management, reproductive ultrasound, sperm management, egg retrieval, artificial insemination, embryo transfer, nutrition, genetics, and certain clinical aspects, such as endocrinology and robustness of reproductive systems.

Introduced in Phnom Penh around 1990, at the twilight of socialism and after two decades of conflict and upheaval, ultrasound took root in humanitarian and then privatized medicine. Services have since multiplied, promising diagnostic information and better prenatal and general health care. In Fixing the Image Jenna Grant draws on years of ethnographic and archival research to theorize the force and appeal of medical imaging in the urban landscape of Phnom Penh. Set within long genealogies of technology as tool of postcolonial modernity, and vision as central to skilled diagnosis in medicine and Theravada Buddhism, ultrasound offers stabilizing knowledge and elicits desire and pleasure, particularly for pregnant women. Grant offers the concept of "fixing"-which invokes repair, stabilization, and a dose of something to which one is addicted-to illuminate how ultrasound is entangled with practices of care and neglect across different domains. Fixing the Image thus provides a method for studying technological practice in terms of specific materialities and capacities of technologies-in this case, image production and the permeability of the body-illuminating how images are a material form of engagement between patients, between patients and their doctors, and between patients and their bodies.

During the last two decades, a new form of trade in commercial surrogacy grew across Asia. Starting in India, a "disruptive" model of surrogacy offered mass availability, rapid accessibility, and created new demands for surrogacy services from people who could not afford or access surrogacy elsewhere. In International Surrogacy as Disruptive Industry in Southeast Asia, Andrea Whittaker traces the development of this industry and its movement across Southeast Asia following a sequence of governmental bans in India, Nepal, Thailand, and Cambodia. Through a case study of the industry in Thailand, the book offers a nuanced and sympathetic examination of the industry from the perspectives of the people involved in it: surrogates, intended parents, and facilitators. The industry offers intended parents the opportunity to form much desired families, but also creates vulnerabilities for all people involved. These vulnerabilities became evident in cases of trafficking, exploitation, and criminality that emerged in southeast Asia, leading to greater scrutiny on the industry as a whole. Yet the trade continues in new flexible hybrid forms, involving the circulation of reproductive gametes, embryos, surrogates, and ova donors across international borders to circumvent regulations. The book demonstrates the need for new forms of regulation to protect those involved in international surrogacy arrangements.

A cutting-edge analysis of the global issues surrounding modern reproductive technologies Advances in assisted reproductive technologies have sparked global policy debates since the birth of the first so-called "test tube baby" in 1978. Today, mitochondrial replacement therapies represent the most recent advancement in assisted reproductive technologies, allowing some women with mitochondrial diseases to birth babies without those diseases. In the past decade, mitochondrial replacement therapies have captured public sentiment, reigniting debates around social views of reproductive rights and the appropriate legal and political response. Reproduction Reborn guides readers through the history and science of mitochondrial replacement therapies and the various attempts to control them. Leading experts from medicine, genetics, ethics, law, and policy explore the influence of public debate on the evolving shape of these technologies and their subsequent regulation. They highlight case studies from both developed and developing countries across the globe, including recent legislation in Australia and China. They further identify the ethical, legal, and societal norms that need to be addressed by policymakers and communities as more and more people seek to gain access to these treatments. Given the importance of reproduction in family life and cultural identity, clinicians and policymakers must understand how regulatory regimes around mitochondrial replacement therapies have evolved to illuminate the processes and challenges of governing reproduction in a fast-moving world. Informative and global in scope, Reproduction Reborn explores how advancements in assisted reproductive technologies challenge core values surrounding the rights and responsibilities of modern-day family units.

Protecting the reproductive potential of young patients undergoing cancer therapy is increasingly important. With modern treatment protocols, 80% of patients can be expected to survive. It has been estimated that up to one in 250 young adults will be a survivor of childhood cancer in the future; infertility, however, may be a consequence. As a wide range of fertility preservation methods are increasingly offered by clinicians, this systematic and comprehensive textbook dealing with the cryobiology, technology and clinical approach to this therapy will be essential reading to infertility specialists, embryologists, oncologists, cryobiologists, ObGyns, andrologists, and urologists with an interest in fertility preservation. Fertility Cryopreservation reviews all the techniques of this increasingly important field within reproductive medicine. It covers the basic principles of pertinent cryobiology, and contains major sections on the different therapies available, written by international specialists combining experience from both academic centers and commercial industries.

Gender and mental health is a growing field in psychiatry and in the last three to four decades, many different aspects of women's mental health have bloomed. Researchers have gained a better understanding of the psychological, social, and cultural aspects of mental health problems in women, and it is possible to describe, classify, and circumscribe different diagnoses as they appear in the female gender. Epidemiological data has also shown an increased frequency in different clinical aspects of many psychiatric disorders. In addition, research into areas including eating disorders, perinatal, psychiatric disorders, and the long term effects of abuse have helped us to appreciate the societal, parental, and personal consequences of mental health problems. The Oxford Textbook of Women and Mental Health is dedicated to fundamental aspects in women's mental health. Part one of the text covers topics from women's health as a global issue to different medical psychological theories, giving an overview of the role of gender in mental health. The second part of the book examines clinical aspects of women and mental health. In part three, special clinical topics such as PTSD, self-harm, menopause, violence and its management are investigated. Part four of the text focuses on parental psychiatric disorders, clarifying how mental health and behavioural problems in children can be a marker or consequence of maternal distress. The final two parts look at the topics of women and disability, and legislation and policy. A book of exceptional scope and depth, it will be essential for all those health professionals involved in managing mental health problems in women.

What is expected of 21st Century egg and sperm donors, and how does being a donor impact on men and women's own personal lives and relationships? How do donors navigate connections and relationships created by donation? What do these connections mean to them, and to the people around them -their partners, parents, siblings and children? Donor conception is becoming increasingly widespread and since the new millennium, we have witnessed a dramatic shift in the way that donor conception is regulated and practiced in many jurisdictions around the world. In the past, donor conception has often been a family secret and donors were, almost by definition, anonymous. Now, 'openness' is seen as the ideal and donors can expect to be traced or contacted by those born from their donations. But what does this shift mean for donors, and their families? This path-breaking book draws on in-depth interviews with donors, their kin and fertility counsellors, and addresses these questions by analysing how understandings of donation are shaped by the regulatory, cultural and relational contexts in which they are formed. The authors also discuss what donation stories can tell us about contemporary understandings of connectedness, time and morality in the context of reproduction and family life, and consider how reproductive 'openness' might be done differently.

In January 1979, Robert Edwards and Patrick Steptoe delivered a lecture detailing the ten-year clinical and scientific research programme that led to the birth of Louise Brown, the first baby born utilising IVF. This thoroughly-researched book provides both a full annotated transcript of the lecture as well as recorded reminiscences from those who attended, detailing the contemporary understandings of the event. An essay on the lecture's historical context adds fresh insight into the biographies of Edwards and Steptoe and highlights sources from print and broadcast media that have received scant attention in earlier publications. Current and future implications of the advances in IVF since the first procedure are also explored, examining future medical and scientific possibilities as well as ethical issues that may arise. A foreword by Louise Brown herself places this remarkable leap of science in a personal context, one that so many families have since experienced themselves.

This open access edited book brings together new research on the mechanisms by which maternal and reproductive health policies are formed and implemented in diverse locales around the world, from global policy spaces to sites of practice. The authors - both internationally respected anthropologists and new voices - demonstrate the value of ethnography and the utility of reproduction as a lens through which to generate rich insights into professionals' and lay people's intimate encounters with policy. Authors look closely at core policy debates in the history of global maternal health across six different continents, including: Women's use of misoprostol for abortion in Burkina Faso The place of traditional birth attendants in global maternal health Donor-driven maternal health programs in Tanzania Efforts to integrate qualitative evidence in WHO maternal and child health policy-making Anthropologies of Global Maternal and Reproductive Health will engage readers interested in critical conversations about global health policy today. The broad range of foci makes it a valuable resource for teaching in medical anthropology, anthropology of reproduction, and interdisciplinary global health programs. The book will also find readership amongst critical public health scholars, health policy and systems researchers, and global public health practitioners.

Now in a completely revised and expanded fourth edition, including two new chapters, this user-friendly textbook offers a succinct overview of both the medical and surgical management of reproductive disorders, as well as coverage of associated imaging modalities. Included here are updated chapters on major reproductive endocrinology and infertility issues, such as polycystic ovary syndrome (PCOS), pubertal disorders, amenorrhea, menopause, management of endometriosis and fibroids (including interventional radiology), laboratory and clinical aspects of assisted reproductive technologies (ART), imaging modalities such as ultrasonography and sonohysterography, hysteroscopic and laparoscopic techniques, an expansion of female infertility and fertility, preimplantation diagnosis and screening, osteoporosis, and contraception and sterilization. Chapters new to this edition discuss third-party reproduction and uterine transplantation. In addition, chapters opens with a list of bulleted key points and end with multiple choice review questions, and most include vibrant clinical case material to illustrate important concepts. Residents, fellows, and new clinicians in obstetrics and gynecology interested in reproductive endocrinology and infertility will find this fourth edition of Clinical Reproductive Medicine and Surgery: A Practical Guide a valuable and focused reference.

In US security culture, motherhood is a site of intense contestation--both a powerful form of cultural currency and a target of unprecedented assault. Linked by an atmosphere of crisis and perceived vulnerability, motherhood and nation have become intimately entwined, dangerously positioning national security as reliant on the control of women's bodies. Drawing on feminist scholarship and critical studies of security culture, Natalie Fixmer-Oraiz explores homeland maternity by calling our attention to the ways that authorities see both non-reproductive and "overly" reproductive women's bodies as threats to social norms--and thus to security. Homeland maternity culture intensifies motherhood's requirements and works to discipline those who refuse to adhere. Analyzing the opt-out revolution, public debates over emergency contraception, and other controversies, Fixmer-Oraiz compellingly demonstrates how policing maternal bodies serves the political function of securing the nation in a time of supposed danger--with profound and troubling implications for women's lives and agency.

Mary Warnock steers a clear path through the web of complex issues underlying the use of new reproductive technologies. She begins by analysing what it means to claim something as a 'right', and goes on to discuss the cases of different groups of people. She also examines the ethical problems faced by particular types of assisted reproduction, including artificial insemination, in-vitro fertilization, and surrogacy, and argues that in the future human cloning may well be a viable and acceptable form of treatment for some types of infertility.