The Fourth Edition of Knobil & Neill will continue to serve as a reference aid for research, to provide the historical context to current research, and most importantly as an aid for graduate teaching on a broad range of topics in human and comparative reproduction. In the decade since the publication of the last edition, the study of reproductive physiology has undergone monumental changes. Chief among these advances are in the areas of stem cell development, signaling pathways, the role of inflammation in the regulatory processes in the various tissues, and the integration of new animal models which have led to a greater understanding of human disease. This new edition will seek to synthesize all of this new information at the molecular, cellular, and organismal levels of organization and present modern physiology a more understandable and comparative context.
*The leading comprehensive work on the physiology of reproduction
*Edited and authored by the world's leading scientists in the field
*Is a synthesis of the molecular, cellular, and organismic levels of organization
*Bibliogrpahics of chapters are extensive and cover all the relevant literature

Die medizinische Behandlung der ungewollten Kinderlosigkeit wird hierzulande nach wie vor mit einer Mischung aus Interesse am medizinisch-technischen Fortschritt und Sorge uber die mogli- cherweise nicht mehr kalkulierbaren Risiken dieses Fortschrittes betrachtet. Die Reaktionen reichen dabei von der implizi ten Gleichsetzung konkreter Formen der Reproduktionsmedizin mit den fiktiven Verhaltnissen in der 'Schonen Neuen welt'1, bis hin zu Einschatzungen, wonach sich die Reproduktionsmedizin in naher Zukunft als ein unverzichtbares Instrument bei der Bekampfung eines langandauernden Bevolkerungsruckganges in der BRD erweisen 2 werde. Auch wenn sich in den letzten 5-10 Jahren das Interesse der Offentlichkeit verstarkt den verschiedenen Formen der medizini- 3 schen Behandlung ungewollter Kinderlosigkeit zugewandt hat, so scheint mit diesem verstarkten Interesse kein Anstieg der Anzahl Der Vergleich des heutigen Potentials der Reproduk- tionsmedizin mit den Schilderungen der industriellen Erzeugung von Menschen in A. Huxleys Roman "Schone Neue Welt" gehort zu den Standardbildern in weiten Teilen der Literatur uber die medizinische Behandlung der ungewollten Kinderlosigkeit. So z.B. auch bei: Hirsch, G. und Eberbach W. (1987): Auf dem Weg zum kunstlichen Leben - Retortenkinder, Leihmutter, pro- grammierte Gene Basel, Boston, Stuttgart. S.31ff. 2 So ein Reproduktionsmediziner in der Fernsehsendung 'Explosiv' (RTL 22.5.'91). 3 Man denke z. B. nur an die Kontroversen im Zuge der Erarbeitung des Embryonenschutzgesetzes, an die Richt- linien zur Durchfuhrung der In-vitro-Fertilisation der Bundesarztekammer, an die Initiativen auf dem 56.

Master the effective evaluation, analysis and management of placental-fetal growth restriction (PFGR), developing strategies to reduce the risk of perinatal mortality and morbidity in patients worldwide. Extensively researched by international experts, this manual provides practitioners with a detailed, hands-on approach to the practical 'pearls' for direct patient management. This authoritative volume advises on matters such as the correct evaluation and management of high-risk patients in danger of PFGR through to delivery. Extensive and wide-ranging, this book is an invaluable companion to the developing research interest and clinical applications in PFGR, including developmental outcomes in early childhood. Featuring a critical evaluation of a variety of abnormal conditions, such as fetal hypoxia and extreme prematurity, which are clearly displayed through extensive illustrations, this essential toolkit ensures that practitioners at all levels can effectively limit adverse outcome and reach the correct diagnosis.

In the mid-1990s, the international community pronounced prenatal sex selection via abortion an "act of violence against women" and "unethical." At the same time, new developments in reproductive technology in the United States led to a method of sex selection before conception; its US inventor marketed the practice as "family balancing" and defended it with the rhetoric of freedom of choice. In Gender before Birth, Rajani Bhatia takes on the double standard of how similar practices in the West and non-West are divergently named and framed. Bhatia's extensive fieldwork includes interviews with clinicians, scientists, biomedical service providers, and feminist activists, and her resulting analysis extends both feminist theory on reproduction and feminist science and technology studies. She argues that we are at the beginning of a changing transnational terrain that presents new challenges to theorized inequality in reproduction, demonstrating how the technosciences often get embroiled in colonial gender and racial politics.

Infertility can have devastating physical, emotional and financial effects on people affected. It is a common problem, but can be hard to talk about, and hard to understand. In this concise book, Dr Kovacs, a reproductive gynaecologist who has spent the past 40 years working with patients facing fertility problems, focuses on and unpicks key misconceptions. In his clear explanations, he covers the basic physiology of conceiving, and describes the areas that have to be explored for those who have not yet been able to conceive. Specific chapters cover the three major problem areas: lack of releasing eggs, sperm problems, and abnormalities of the female passages. Treatment options are discussed for each of these areas, including technical details and a brief readable overview of their history. The many ways of parenting which are now available are also detailed. This is a recommended read for couples wanting to conceive, their friends and families, and anyone who wants to understand fertility.

Substantial Relations examines global reproductive medicine in India, focusing on in vitro fertilization. Since the 1970s, India has played a central but shifting role in shaping global reproductive medicine-from a provider of raw material, to a producer of knowledge and technology, to a creator of a thriving medical market that attracts patients from all over the world. Relying on archival material and oral history, Substantial Relations traces the path of this transnational historical trajectory. This book also examines the contemporary making of IVF in Delhi. Drawing on ethnographic research in homes, hospitals, and laboratories, Sandra Barnreuther provides deep insights into the intricacies of clinical life and everyday experience by depicting IVF users' quest for offspring and their fears of establishing unwanted ties, as well as the minute engagements of clinicians and laboratory staff with reproductive substances. Thinking through substances-metaphorically and materially-Sandra Barnreuther provides a novel and rich analysis of the various relations that the burgeoning IVF sector in India has relied on and generated. Substantial Relations contributes to a broader understanding of reproductive medicine as a global phenomenon constantly in the making, situating India in the midst of, rather than peripheral to, this process.