Substantial Relations examines global reproductive medicine in India, focusing on in vitro fertilization. Since the 1970s, India has played a central but shifting role in shaping global reproductive medicine-from a provider of raw material, to a producer of knowledge and technology, to a creator of a thriving medical market that attracts patients from all over the world. Relying on archival material and oral history, Substantial Relations traces the path of this transnational historical trajectory. This book also examines the contemporary making of IVF in Delhi. Drawing on ethnographic research in homes, hospitals, and laboratories, Sandra Barnreuther provides deep insights into the intricacies of clinical life and everyday experience by depicting IVF users' quest for offspring and their fears of establishing unwanted ties, as well as the minute engagements of clinicians and laboratory staff with reproductive substances. Thinking through substances-metaphorically and materially-Sandra Barnreuther provides a novel and rich analysis of the various relations that the burgeoning IVF sector in India has relied on and generated. Substantial Relations contributes to a broader understanding of reproductive medicine as a global phenomenon constantly in the making, situating India in the midst of, rather than peripheral to, this process.

This open access book addresses self-care on sexual and reproductive health and rights and HIV prevention and treatment in the most marginalized and vulnerable communities. Case studies and personal narratives are used to share their perspectives and experiences, sources of information for self-care products, motivations for self-care, and challenges and outcomes. Self-care provides the way to reach the last mile in achieving universal health coverage and the Sustainable Development Goals. Issues related to stigma, discrimination and violence among these communities are highlighted. Changes in policies and programs to improve their sexual and reproductive health, education and employment are discussed. The last chapter in the book examines how the agenda on self-care can be advanced in the years ahead. The audience for this publication includes health professionals, researchers, those managing health institutions and service providers.

In the 1960s thousands of poor women of color on the (post)colonial French island of Reunion had their pregnancies forcefully terminated by white doctors; the doctors operated under the pretext of performing benign surgeries, for which they sought government compensation. When the scandal broke in 1970, the doctors claimed to have been encouraged to perform these abortions by French politicians who sought to curtail reproduction on the island, even though abortion was illegal in France. In The Wombs of Women-first published in French and appearing here in English for the first time-Francoise Verges traces the long history of colonial state intervention in black women's wombs during the slave trade and postslavery imperialism as well as in current birth control politics. She examines the women's liberation movement in France in the 1960s and 1970s, showing that by choosing to ignore the history of the racialization of women's wombs, French feminists inevitably ended up defending the rights of white women at the expense of women of color. Ultimately, Verges demonstrates how the forced abortions on Reunion were manifestations of the legacies of the racialized violence of slavery and colonialism.

Reproductive donation is the most contentious area of assisted reproduction. Even within Europe there are wide variations in what is permitted in each country. This multi-disciplinary book takes a fresh look at the practices of egg, sperm and embryo donation and surrogacy, bringing together ethical analysis and empirical research. New evidence is offered on aspects of assisted reproduction and the families these create, including non-traditional types. One of the key issues addressed is should children be told of their donor origin? If they do learn the identity of their donor, what kinds of relationships may be forged between families, the donor and other donor sibling families? Should donation involve a gift relationship? Is intra-familial donation too close for comfort? How should we understand the growing trend for 'reproductive tourism'? This lively and informed discussion offers new insights into reproductive donation and the resulting donor families.

Spermatogenesis is a tightly regulated cellular renovation and differentiation process. It consists of self-renewal and differentiation of spermatogonial stem cells (SSCs), spermatocytic meiosis and spermiogenesis; each of these processes is essential to the continuous, successful production of male gametes. During spermiogenesis, haploid spermatids undergo extensive cellular, molecular and morphological changes, including acrosome biogenesis, flagellum development, cytoplasmic reorganization and chromatin condensation. These changes ultimately result in mature spermatozoa with an acrosome-covered head and motile tail. In this book, Chapter One summarizes the progress that has been made in understanding the molecular mechanisms underlying acrosome biogenesis, and the authors discuss the potential directions of future investigations of this process. Chapter Two briefly addresses the basics of spermatogenesis and the synthesis of ncRNAs, and then the authors discuss the recent progress in understanding of the functions of miRNAs, endo-siRNAs, piRNAs and lncRNAs in the regulation of spermatogenesis. Chapter Three provides a review of the current literature on testicular immunoregulation and its underlying mechanisms, along with its effect on testicular functions.

While the practice of surrogacy has existed for millennia, new fertility technologies have allowed women to act as gestational surrogates, carrying children that are not genetically their own. While some women volunteer to act as gestational surrogates for friends or family members, others get paid for performing this service. The first ethnographic study of gestational surrogacy in the United States, Labor of Love examines the conflicted attitudes that emerge when the ostensibly priceless act of bringing a child into the world becomes a paid occupation. Heather Jacobson interviews not only surrogate mothers, but also their family members, the intended parents who employ surrogates, and the various professionals who work to facilitate the process. Seeking to understand how gestational surrogates perceive their vocation, she discovers that many regard surrogacy as a calling, but are reluctant to describe it as a job. In the process, Jacobson dissects the complex set of social attitudes underlying this resistance toward conceiving of pregnancy as a form of employment. Through her extensive field research, Jacobson gives readers a firsthand look at the many challenges faced by gestational surrogates, who deal with complicated medical procedures, delicate work-family balances, and tricky social dynamics. Yet Labor of Love also demonstrates the extent to which advances in reproductive technology are affecting all Americans, changing how we think about maternity, family, and the labor involved in giving birth.

El problema de la esterilidad e infertilidad en las parejas hoy dia esta poniendo en riesgo la capacidad de reemplazo generacional en Europa. Segun la Organizacion Mundial de la Salud (OMS), alrededor del 10 al 15% de las parejas en edad de procrear consultan al medico por problemas de esterilidad. El objetivo de este manual es actualizar los conocimientos y adiestrar en los procedimientos para evaluar la calidad del semen, ayudar al diagnostico de la subfertilidad y esterilidad de origen masculino. Va dirigido al personal en formacion y a profesionales del ambito sanitario, principalmente del laboratorio (tecnicos y facultativos) pero tambien a los clinicos prescriptores (urologos y ginecologos).

In their desperate quest for conception, thousands of infertile couples from around the world travel to the global in vitro fertilization (IVF) hub of Dubai. In Cosmopolitan Conceptions Marcia C. Inhorn highlights the stories of 220 "reprotravelers" from fifty countries who sought treatment at a "cosmopolitan" IVF clinic in Dubai. These couples cannot find safe, affordable, legal, and effective IVF services in their home countries, and their stories offer a window into the world of infertility-a world that is replete with pain, fear, danger, frustration, and financial burden. These hardships dispel any notion that traveling for IVF treatment is reproductive tourism. The magnitude of reprotravel to Dubai, Inhorn contends, reflects the failure of countries to meet their citizens' reproductive needs, which suggests the necessity of creating new forms of activism that advocate for developing alternate pathways to parenthood, reducing preventable forms of infertility, supporting the infertile, and making safe and low-cost IVF available worldwide.

Putting the ethical tools of philosophy to work, Ellen K. Feder seeks to clarify how we should understand "the problem" of intersex. Adults often report that medical interventions they underwent as children to "correct" atypical sex anatomies caused them physical and psychological harm. Proposing a philosophical framework for the treatment of children with intersex conditions one that acknowledges the intertwined identities of parents, children, and their doctors Feder presents a persuasive moral argument for collective responsibility to these children and their families."

Omdat mensen nietzelf kunnen kiezen volgens welk receptzijhun kinderwens vorm geven, is begnip en respect erg belangrijk. Dit boekje is een schitterend instrument om kinderen te introduceren in de complexe wereld van fertiliteitsbehandelingen. Het ontdoet de problematiek van de taboes waarmee fertilieteitsbehandelingen vaak nog zijn omgeven en helpt inzien dat het niet uitmaakt volgens welk recept je op de wereld gekomen bent. Kortom, een aanrader voor groot en klein"

It is estimated that more than 4.5 million couples experience infertility each year, and more than 4 million babies have been born using IVF since 1978. However, assisted reproductive technologies continue to raise many medical, social, ethical, political and religious questions, often leading to controversial and sometimes inaccurate opinions about the outcomes of pregnancies resulting from these techniques. This is the first book dedicated to pregnancies arising from assisted reproductive technologies (ART). Chapters cover the most important management issues, from early pregnancy to outcome of children resulting from ART, including gynaecological, genetic and obstetric complications. Each chapter is written and edited by leading experts in the field of human reproduction. A timely, practical and evidence-based guide to the management of ART pregnancies, based on 30 years of clinical experience, this is essential reading for reproductive and maternal-fetal specialists as well as general obstetricians and gynaecologists.

IVF is a major treatment in infertility when other methods of assisted reproductive technology have failed. The process involves hormonally controlling the ovulatory process, removing ova (eggs) from the woman's ovaries and letting sperm fertilise them in a fluid medium. This book presents topical research in the study of in vitro fertilisation including management of chronic viral infections in assisted reproduction; posthumous sperm procurement; assisted reproductive technologies for serodiscordant couples with an HIV-1 infection and the impact of laparoscopic ovarian cystectomy for infertile women with endometriomas prior to IVF/ICSI cycles.

The reproductive system and all of its functions related to sex, conception, pregnancy and delivery, all actions aimed at keeping it functioning optimally and free from diseases and harmful traditional practices are explored in this book.

The ready availability of donated sperm and eggs has made possible an entirely new form of family. Children of the same donor and their families, with the help of the internet, can now locate each other and make contact. Sometimes this network of families form meaningful connections that blossom into longstanding groups, and close friendships. This book is about unprecedented families that have grown up at the intersection of new reproductive technologies, social media and the human desire for belonging. Random Families asks: Do shared genes make you a family? What do couples do when they discover that their children shares half their DNA with a dozen or more other offspring from the same sperm donor? What do kids find in common with their donor siblings? What becomes of these chance networks once parents and donor siblings find one another? Based on over 350 interviews with children (ages 10-28) and their parents from all over the U.S., Random Families chronicles the chain of choices that couples and single mothers make from what donor to use to how to participate (or not) in donor sibling networks. Children reveal their understanding of a donor, the donor's spot on the family tree and the meaning of their donor siblings. Through rich first-person accounts of network membership, the book illustrates how these extraordinary relationships-woven from bits of online information and shared genetic ties- are transformed into new possibilities for kinship. Random Families offers down-to-earth stories from real families to highlight just how truly distinctive these contemporary new forms of family are.

Whether you're a newly diagnosed patient, or a friend or relative of someone suffering from benign prostate disease, this book offers help. The only text to provide the doctor's and patient's views, 100 Questions & Answers Prostate Disease gives you authoritative, practical answers to your questions about the disease, including diagnosis, medical and surgical treatment options, sources of support, and much more. Written by an expert on the subject, Dr. Kevin R. Loughlin, with actual patient commentary from John Nimmo, this book is an invaluable resource for anyone coping with the physical and emotional turmoil of prostate disease.