It is the book for every woman who hopes for VBAC. In fact, many first-time cesareans could be avoided if this book were read first. It is thorough, it is compassionate. "Esther Zorn, Cesarean Prevention Movement"

A] landmark book. . . . These VBAC stories are inspiring, as well as very informative about the nature of labor and current U.S. obstetric practice. "Ina May Gaskin, The Birth Gazette"

This is not a dry text book remote from reality, but a powerful manual' that burns the knowledge women need in an indelible way on heart and mind. "AIMS Quarterly Journal"

Here for the first time are intimate stories of the VBAC (vaginal birth after cesarean) experience, as told by mothers, fathers, midwives, obstetricians, labor coaches, and others whose lives have been affected by VBAC. The stories demystify in a powerful way the idea of once a cesarean, always a cesarean. By example, each story is a telling critique of birthing practices in general and the cesarean outcome in particular, as well as a primer for mothers, fathers, and professionals on the VBAC experience.

Reports on the study of drug consumption by 602 pregnant women.

Human Placental Trophoblasts: Impact of Maternal Nutrition explores the vital roles of trophoblasts play in fetal growth and pregnancy, giving you new insight into the modulation of placental trophoblast functions by nutrients. It also reviews the role of fatty acids, folic acids, and specific vitamins in this aspect. The book highlights the critical role of nutrients on human placental development and its' in utero programming effects on the development of chronic diseases such as type 2 diabetes, cardiovascular diseases, hypertension, and obesity in later life. The book begins with discussions of the central process of placentation and its regulation on size and growth of the fetus. It also covers the effects of key macronutrients on placental growth, metabolism, transport, and secretory function. The text details important vitamins and few micronutrients and their roles in the feto-placental growth and development. It includes information on the influence of maternal lifestyle and environmental factors on regulation of the growth, metabolism and gene expression in the feto-placental unit. A review of the genes linked to the process of placentation rounds out the coverage. An examination of a broad range of evidence in the areas of placental growth, function, and its impact on feto-placental outcome, the book presents new knowledge on nutrition and its relevance with early human development. This includes not only the effects of maternal nutrients on possible neonatal growth and development but also their regulation by maternal lifestyle associated factors. A fine blending of epidemiology, clinical nutrition, perinatal and neonatal medicine, and biochemistry and molecular biology areas of research activities, the book helps you to understand the impact of maternal nutrition on placentation and its relevance with pregnancy outcome and fetal programming of adult health and disease.

Mammalian Endocrinology and Male Reproductive Biology provides comprehensive and current coverage of the area of endocrinology and male reproductive biology, covering not just humans, but mammals in general. Written by international experts in their respective fields, this multi-author book also covers the latest developments in genomics of androgen action and male infertility. The book begins by covering sexual dimorphism in the central nervous system; structure, control of secretion and function of GnRH; and gonadotropins of pituitary origin and their role in gonadal functions. This is followed by an account of hormonal regulation of spermatogenesis, and the role of apoptosis in this process. Subsequent chapters center around epididymis, regulation of growth and function, and sperm motility regulation. The last chapters in the book discuss the structure and function of male accessory sex glands with associated pathologies as well as recent updates in male contraception, mechanism of androgen action, and genomics of male infertility. Wherever necessary, tables and figures have been added for a better understanding. Each chapter is appropriately referenced and contains current information on the latest developments in the field.

Reproductive donation is the most contentious area of assisted reproduction. Even within Europe there are wide variations in what is permitted in each country. This multi-disciplinary book takes a fresh look at the practices of egg, sperm and embryo donation and surrogacy, bringing together ethical analysis and empirical research. New evidence is offered on aspects of assisted reproduction and the families these create, including non-traditional types. One of the key issues addressed is should children be told of their donor origin? If they do learn the identity of their donor, what kinds of relationships may be forged between families, the donor and other donor sibling families? Should donation involve a gift relationship? Is intra-familial donation too close for comfort? How should we understand the growing trend for 'reproductive tourism'? This lively and informed discussion offers new insights into reproductive donation and the resulting donor families.

The first and second editions of this successful textbook have been highly praised for their lucid and detailed coverage of abstract algebra. In this third edition, the author has carefully revised and extended his treatment, particularly the material on rings and fields, to provide an even more satisfying first course in abstract algebra.

Regulatory agencies worldwide have issued directives or such requirements for air quality standards in embryology laboratories. This practical guide reviews the application of clean room technology or controlled environments specifically suited for Assisted Reproductive Technology (ART) Units. Its comprehensive coverage includes material on airborne particles and volatile organic compounds, including basic concepts, regulation, construction, materials, certification, clinical results in humans, and more.

Unlike conventional single daily observations, time lapse technology provides hundreds of images, which allows pinpointing of key events in the embryo's in vitro development as well as the detection of brief but significant critical changes. This information is beneficial in selecting the most viable embryos from a cohort and increases the chances of a positive outcome. The Atlas of Time Lapse Embryology describes in detail the technology and techniques surrounding time lapse embryology. The book also covers the clinical aspects of time lapse imaging, morphokinetic timings, implantation data, fertilization, compaction, blastulation, irregular cleavages, multinucleation, vacuolation, zona defects, and other topics. The book is easy to read, practical, and illustrated with dozens of images and video clips to help explain a variety of concepts. It will help practitioners to better understand how time lapse monitoring may dramatically increase flexibility in the IVF clinic, and most importantly, enhance clinical outcomes. Print Versions of this book also include access to the ebook version.

It is estimated that more than 4.5 million couples experience infertility each year, and more than 4 million babies have been born using IVF since 1978. However, assisted reproductive technologies continue to raise many medical, social, ethical, political and religious questions, often leading to controversial and sometimes inaccurate opinions about the outcomes of pregnancies resulting from these techniques. This is the first book dedicated to pregnancies arising from assisted reproductive technologies (ART). Chapters cover the most important management issues, from early pregnancy to outcome of children resulting from ART, including gynaecological, genetic and obstetric complications. Each chapter is written and edited by leading experts in the field of human reproduction. A timely, practical and evidence-based guide to the management of ART pregnancies, based on 30 years of clinical experience, this is essential reading for reproductive and maternal-fetal specialists as well as general obstetricians and gynaecologists.

A new subspecialty is growing at the interface of reproductive medicine and perinatology: infertility. Textbook of Periconceptional Medicine provides an authoritative and comprehensive reference resource for those providing medical care to women trying to conceive a healthy pregnancy.

A revolutionary first edition, this text brings together a number of difficult and usually separate topics and provides the busy clinician with one authoritative and methodical reference.

Reflecting the breadth of modern clinical practice in this emerging therapy area, this integrated text incorporates aspects of all the relevant existing expertise, including:

• Preconceptual counseling
• Fertility investigation
• Therapy and management of preconception through the first trimester of pregnancy

Highlighting latest advances in genetics and biochemistry, the completely revised Third Edition reviews the field from basic science, clinical, epidemiological, and regulatory perspectives. Contributions from top opinion leaders in the field bring together developments in molecular embryology and cell biology as they apply to problems in developmental toxicology. It covers testing of pharmaceutical and environmental agents and interpretation of developmental toxicology data, highlighting mathematical and statistical techniques, as well as the effects of toxic exposure on the functional development of various organs. The relationship between maternal and developmental toxicology is examined, in addition to current techniques for studying chemical disposition, metabolism, and placental transfer. Close attention is given to the regulatory aspects of testing and risk assessment. Pre- and postconceptional clinical care and genetic factors in clinical developmental toxicology are also discussed. Key topics include: the roles of apoptosis and signal transduction pathways in normal and abnormal development the role of epigenetic changes in development the role of nutrition and individual susceptibility the utility of bioinformatics global and targeted gene expression changes

The first edition of The Endometrium was a landmark publishing event in reproductive biology and medicine. Many important developments have occurred in the field, and this new edition has been substantially updated and expanded to include new topics with an improved format. With the addition of several new authors and topics, the Second Edition of The Endometrium has developed new coverage of transcriptomics, stem cells, genetics and in-utero programming. Other new areas strengthen to include: placentology in human and animal models, taking account of the tremendous current interest in the maternal-fetal interface and its role in pregnancy pathology, neonatal and adult health. The layout has also been improved in order to aid browsing and cross-referencing. This is an invaluable up-to-date innovative text that will appeal to a worldwide spectrum of academic and professional readers including postgraduate and postdoctoral researchers in reproductive biology. As well as trainees and health care professionals in obstetrics and gynecology and allied disciplines such as assisted reproduction and oncology. A panel of internationally respected authors has been carefully chosen for their insight, clear, fair writing style and scholarly perspective.

Advances in Pregnancy-Related Protein Research describes the most significant advances in pregnancy-related protein research that have occurred over the last 25 years. The fetal, pregnancy, placental, and endometrial proteins discussed are classified by their origin and biological activity. The structure and function of newly discovered pregnancy protein families are examined in detail. Physiological values of various pregnancy and placental proteins are presented, and the pathophysiological significance of diagnostic and therapeutic data is addressed. Advances in Pregnancy-Related Protein Research will be a useful reference for obstetricians, oncologists, immunologists, reproduction specialists, oncodevelopmental biologists, gynecologists, and other researchers interested in the subject.

When an individual or couple is considering a difficult choice such as IVF treatment or third party assisted conception, the moral and ethical basis for their decisions may often be informed by their particular faith traditions. Faith and Fertility is a comprehensive collection of essays by academics and faith leaders from around the world. The reader is introduced to the cultural and religious understanding of fertility as it is practised among diverse international faith traditions. Each chapter is written in an accessible and clear style, outlining each faith's history and its core beliefs and values, showing the influence these have on its moral and ethical perspective on the issues surrounding fertility. This book will be a welcome resource for anyone seeking information on the plethora of attitudes towards fertility that are at work in today's global and multi-cultural world.

Modelled after the current MRCOG curriculum, the new edition of this bestselling book provides all the information a specialist registrar in obstetrics and gynaecology or senior house officer needs during training or when preparing for the MRCOG examination. Obstetrics & Gynaecology: An Evidence-based Text for MRCOG covers the latest professional guidelines and developments in obstetrics and gynaecology and continues to provide an easily accessible source of information for those practising as specialists. The book's subsections within obstetrics and gynaecology are divided in line with the RCOG trainee logbook. The text is consistently structured throughout to ensure ease of reference with standardized headings including definitions, incidence, aetiology, investigations and management. Focusing on standards and an evidence-based approach, each chapter includes material on MRCOG standards in an easy-to-consult format. Information on evidence-based medicine is also included to provide a rapid summary of the evidence relating to the interventions and treatments discussed. This text will continue to be an invaluable companion to the higher training of obstetricians and gynaecologists and a useful ready reference for those in established practice.

In the thirty years since the first "test-tube baby," in-vitro fertilization and other methods of reproductive assistance have become a common aspect of family life and medicine in developed nations--and, increasingly, throughout the world. This collection brings together ethnographic studies of how these reproductive technologies are deployed across a wide variety of nations and cultures, taking special account of how they are linked to aspirations towards modernity--and how they contribute to an ongoing reconfiguration of the boundaries of knowledge and human agency. The resulting volume offers both a current snapshot of the cultural state of reproductive technologies and a plethora of provocative questions for the future.

Sound Advice on Symptoms and Treatment, Newly Revised and Updated Edition

Expert information presented in a clear and accessible style.

Prostate problems eventually trouble more than half of all American males, and cancer of the prostate is the second most common cause of death from cancer among men in this country. This comprehensive book on the prostate for general readers is based on an eminent urologist’s thirty years of clinical experience.

Stephen N. Rous covers healthy prostate function, the diseases—both malignant and nonmalignant—that can affect the prostate, treatment choices for the different conditions, and any expected aftereffects. He addresses frankly and compassionately a frequent fear that patients have: loss of sexual potency.

Rous looks at the latest developments in treatment for prostate problems. He explains surgical and radiation therapy for cancer of the prostate and fully discusses nonsurgical options. For this newly revised and updated edition, he has added the latest information on the tests and treatments for prostate problems.

Over 100,000 copies sold.