The critically acclaimed laboratory standard, Methods in Enzymology, is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. The series contains much material still relevant today - truly an essential publication for researchers in all fields of life sciences.

The essays in Copernirus and his Successors deal both with the influences on Copernicus, including that of Greek and Arabic thinkers, and with his own life and attitudes. They also examine how he was seen by contemporaries and finally describe his relationship to other scientists, including Galileo, Brahe and Kepler.

Just how far did Charles Darwin's luck - both good and bad - affect his life and scientific discoveries? One might make a case for saying that Darwin's life was dogged by ill-luck (or perhaps ill-fortune is more appropriate). His mother died when he was seven; he was sent to a school at which he 'learnt little'; he left Edinburgh Medical School after two years, unqualified. He undertook a five-year voyage although he was prone to sea-sickness; his girlfriend (of whom there is evidence he was very fond) married someone else a few months into this voyage. He was affected by ill-health throughout much of his life. One of his children appears to have been mentally handicapped and this child, and also his beloved Annie, died in infancy. In addition to all this, his brother became addicted to drugs.On the other hand one could argue that he had a privileged and fortunate life - perhaps the more common view. At a number of key points in his life he made a choice, or others made a choice, or circumstances occurred, that profoundly influenced the path that he took. There is a school of thought, one that this book investigates, that although Darwin came to the right conclusions, he did not actually follow the right path in getting there. While his science was sometimes flawed, he had the distinct knack of good instinct. Whilst on his voyage to the Galapagos vital evidence that would have led to his theories becoming clearer quite literally slipped through his fingers - Galapagos turtles were caught, examined and their shells thrown overboard. Had he been more thorough, Darwin may have noticed that the clues to his theory of evolution were on these very shells.

The zodiac was first clearly defined by the Babylonians some 2500 years ago, but until recently the basis of this original definition remained unknown. This zodiac of the Babylonians, known as the sidereal zodiac because it is specified in direct relation to the stars (Latin sideris, 'starry'), was used for centuries throughout the ancient world, all the way to India, and must be distinguished from the tropical zodiac in widespread use by astrologers in the West today, which was introduced only in the middle of the second century A.D. by the Greek astronomer Claudius Ptolemy. Such was Ptolemy's influence, however, that the tropical zodiac gained prominence and, except for its survival (in a variant form) in India, knowledge of the sidereal zodiac was lost. In this thrilling study of the history of the zodiac, first submitted in 2004 as his Ph.D. thesis, Robert Powell rescues the the sidereal zodiac from the dusts of time, tracing it back to the Babylonians in the sixth/fifth centuries B.C. The implications of this discovery-among them the restitution of the sideral zodiac to its rightful place at the heart of astrology-are immense, they key point being that the signs of the sidereal zodiac, each thirty degrees long, coincide closely with the twelve astronomical constellations of the same name, whereas the signs of the tropical zodiac, since they are defined in relation to the vernal point, now have no direct relationship to the corresponding zodiacal constellations, owing to the precession of the equinoxes.This revolutionary history of the zodiac includes chapters on the Egyptian decans and the Hindu nakshatras, showing how these sidereal divisions, which originated in Egypt and India, are related to the original Babylonian zodiac. It also sheds light on the controversy surrounding the 'zodiac question' (tropical vs. sidereal), illuminating the history of the tropical zodiac-showing that originally it was not a zodiac at all, but a calendar for describing the course of the seasons This book, the fruit of thirty years of research, is intended not only for scholars but for general readers as well, and offers the clearest and most comprehensive study of the history of the zodiac yet published.

This book tells the curious story of an unexpected finding that sheds light on a crucial moment in the development of physics: the discovery of artificial radioactivity induced by neutrons. The finding in question is a notebook, clearly written in Fermi's handwriting, which records the frenzied days and nights that Fermi spent experimenting alone, driven by his theoretical ideas on beta decay. The notebook was found by the authors while browsing through documents left by Oscar D'Agostino, the chemist among Fermi's group. From Fermi's notes, they reconstruct with skill and expertise the detailed timeline of the critical days leading up to his vital discovery. While much is already known about the road that led Fermi to his important result, this is the first time that it has been possible to reconstruct precisely when and how the initial evidence of neutron-induced decay was obtained. In relating this fascinating story, the book will be of great interest not only to those with a passion for the history of science but also to a wider audience.

In this enlightening and provocative exploration, Dave Pruett sets out a revolutionary new understanding of our place in the universe, one that reconciles the rational demands of science with the deeper tugs of spirituality. Defining a moment in human self-awareness four centuries in the making, Reason and Wonder: A Copernican Revolution in Science and Spirit offers a way to move beyond the either/or choice of reason versus intuition-a dichotomy that ultimately leaves either the mind or the heart wanting. In doing so, it seeks to resolve an age-old conflict at the root of much human dysfunction, including today's global ecological crisis. An outgrowth of C. David Pruett's breakthrough undergraduate honors course, "From Black Elk to Black Holes: Shaping Myth for a New Millennium," Reason and Wonder embraces the insights of modern science and the wisdom of spiritual traditions to "re-enchant the universe." The new "myth of meaning" unfolds as the story of three successive "Copernican revolutions"-cosmological, biological, and spiritual-offers an expansive view of human potential as revolutionary as the work of Copernicus, Galilleo, and Darwin.

Since the first attempts by Europeans to penetrate Greenland's interior in the 18th century, its geometric center, Eismitte ("middle ice" in German), has been one of the most forbidding but scientifically rich locations in the Arctic. Tracing its history from European contact through to the Cold War, this study shows how Eismitte was a setting for scientific knowledge production as well as diplomatic maneuvering, providing new insights into the history of polar exploration and the intertwining of the scientific and geopolitical spheres. Author Janet Martin-Nielsen draws on new research in private, government, military, and institutional archives in multiple countries to explain how this very remote place became a highly charged site of collaboration, contestation, and competition.

This book presents the entire body of thought of Norbert Wiener (1894-1964), knowledge of which is essential if one wishes to understand and correctly interpret the age in which we live. The focus is in particular on the philosophical and sociological aspects of Wiener's thought, but these aspects are carefully framed within the context of his scientific journey. Important biographical events, including some that were previously unknown, are also highlighted, but while the book has a biographical structure, it is not only a biography. The book is divided into four chronological sections, the first two of which explore Wiener's development as a philosopher and logician and his brilliant interwar career as a mathematician, supported by his philosophical background. The third section considers his research during World War II, which drew upon his previous scientific work and reflections and led to the birth of cybernetics. Finally, the radical post-war shift in Wiener's intellectual path is considered, examining how he came to abandon computer science projects and commenced ceaseless public reflections on the new sciences and technologies of information, their social effects, and the need for responsibility in science.

This book addresses important current and historical topics in astrobiology and the search for life beyond Earth, including the search for extraterrestrial intelligence (SETI). The first section covers the plurality of worlds debate from antiquity through the nineteenth century, while section two covers the extraterrestrial life debate from the twentieth century to the present. The final section examines the societal impact of discovering life beyond Earth, including both cultural and religious dimensions. Throughout the book, authors draw links between their own chapters and those of other contributors, emphasizing the interconnections between the various strands of the history and societal impact of the search for extraterrestrial life. The chapters are all written by internationally recognized experts and are carefully edited by Douglas Vakoch, professor of clinical psychology at the California Institute of Integral Studies and Director of Interstellar Message Composition at the SETI Institute. This interdisciplinary book will benefit everybody trying to understand the meaning of astrobiology and SETI for our human society.

This is the first transnational study of British, Norwegian, and Swedish engagement with the Antarctic, from the years before the Great War to the early years of the Cold War. Rather than charting how Europeans unveiled the Antarctic, it uses the history of Antarctic activity as a window into the political and cultural worlds of twentieth-century Britain and Scandinavia. Science was a resource for states attempting to reveal - and control - the Antarctic and its resources. But it was also a source of personal and institutional capital, a means of earning civic status and professional advancement. The book ranges from the politics of whaling management to the changing value of geographical exploration in the academy and the rise of specialized, state-sponsored research, presenting an episodic rather than a linear narrative focused on historically specific networks and strategies. Drawing upon scholarship in critical geopolitics, imperial environmental history, and the cultural history of science, author Peder Roberts argues that despite its splendid geographical isolation, the Antarctic was a field for distinctly local European dreams.

Judaism and Science canvases three millennia of Jewish attitudes towards nature and its study. It answers many questions about the complex relationship of religion and science. How did religious attitudes and dogmas affect Jewish attitudes towards natural knowledge? How was Jewish interest in science reflected, and was facilitated by, links with other cultures - Egypt and Assyria and Babylon in ancient times, Moslem culture in medieval times, and Christian culture during the Renaissance and since? How did science serve as a bridge between religious communities that were otherwise estranged and embattled? How did science serve as a vehicle of assimilation into the wider intellectual culture in which Jews found themselves? The book considers the attitudes and work of particular Jews in different epochs. It takes an "eagle's-eye view" of its subject, considering broad themes from a high vantage, but also swooping down to consider particular individuals at high focus, and in detail. Judaism and Science encompasses the entire history of the interaction of Jews and natural knowledge. BLPart I: The Sages of Israel and Natural Wisdom describes the images of nature and natural philosophy in the two most important sets of books on the Jewish bookshelf: the Biblical corpus and the Talmudic/Early Rabbinic corpus Part II: Jews and Natural Philosophy shows how Jews explained nature, especially the nature of the heavens, or astronomy and astrology, in medieval times and early modern times. BLPart III: Jews and Science -- describes the entry of Jews into modern science, beginning in 19th century Europe and 20th century United States, USSR and Israel, emphasizing the social background of the rapid entryof Jews into modern sciences, and of their remarkable successes. BLThe volume includes annotated primary source documents, a timeline of important events, and an bibliography of essential primary and secondary sources for further research..

This volume challenges the common belief that scientific knowledge is international. Employing case studies from Austria, Poland, the Czech lands, and Hungary, the authors show how scientists in the late Habsburg Monarchy confronted the problem of simultaneously nationalizing and internationalizing their knowledge in a multi-national empire during the 'age of nationalism'. The case studies go beyond traditional emphasis on history, ethnology or other 'national' disciplines, ranging from chemistry and physics to natural history, geology, seismology, surgery, linguistics and eugenics, focusing inter alia on scientific terminology in various national languages, supra-national networks of observation or data gathering, language issues in science education, and research practices in cross-national comparison.

The Evolution of Scientific Knowledge aims to reach a unique understanding of science with the help of economic and sociological theories. The economic theories used are institutionalist and evolutionary. The sociological theories draw from the type of work on social studies of science that have, in recent decades, transformed our picture of science and technology. Science - and more broadly research - is a field where economics and sociology meet in an attempt to understand how complex organizations emerge and work. While the authors argue that science is neither an institution nor an order that emerged as the result of conscious and willful design, nor is it like a 'normal' market, they also acknowledge that science has aspects of market orders and aspects of orders created by design. Furthermore, science develops in specific ways that are to some extent like the development of economic systems, and at the same time are very different. This fascinating book will be of great interest to economists, philosophers, historians and sociologists by focussing on a multidisciplinary understanding of science.

Thomas Gold (1920-2004) had a curious mind that liked to solve problems. He was one of the most remarkable astrophysicists in the second half of the twentieth century, and he attracted controversy throughout his career. Based on a full-length autobiography left behind by Thomas Gold, this book was edited by the astrophysicist and historian of science, Simon Mitton (University of Cambridge).

The book is a retrospective on Gold's remarkable life. He fled from Vienna in 1933, eventually settling in England and completing an engineering degree at Trinity College in Cambridge. During the war, he worked on naval radar research alongside Fred Hoyle and Hermann Bondi - which, in an unlikely chain of events, eventually led to his working with them on steady-state cosmology. In 1968, shortly after their discovery, he provided the explanation of pulsars as rotating neutron stars.

In his final position at Cornell, he and his colleagues persuaded the US Defense Department to fund the conversion of the giant radio telescope at Arecibo in Puerto Rico into a superb instrument for radio astronomy. Gold's interests covered physiology, astronomy, cosmology, geophysics, and engineering.

Written in an intriguing style and with an equally intriguing foreword by Freeman Dyson, this book constitutes an important historical document, made accessible to all those interested in the history of science.

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Christoph Laucht offers the first investigation into the roles played by two German-born emigre atomic scientists, Klaus Fuchs and Rudolf Peierls, in the development of British nuclear culture, especially the practice of nuclear science and the political implications of the atomic scientists' work, from the start of the Second World War until 1959.

This book paints a comprehensive portrait of Mexico's system of assisted reproduction first from a historical perspective, then from a more contemporary viewpoint. Based on a detailed analysis of books and articles published between the 1950s and 1980s, the first section tells the story of how the epistemic, normative, and material infrastructure of the assisted reproduction system was built. It traces the professionalization process of assisted reproduction as a medical field and the establishment of its professional association. Drawing on ethnographic material, the second part looks at how this system developed and flourished from the 1980s up to 2010, its commercialization process, how the expansion of reproductive services took place, and the messages regarding reproductive technologies that circulated within a wide discursive landscape. Given its scope and methods, this book will appeal to scholars interested in science and technology studies, reproduction studies, history of medicine, medical anthropology, and sociology.

Evolutionary theory addresses the phenomenon of the origin and diversity of plant and animal species that we observe. In recent times, however, it has become a predominant ideology which has gained currency far beyond its original confines. Attempts to understand the origin and historical development of human culture, civilization and language, of the powers of human cognition, and even the origin of the moral and ethical values guiding and constraining everyday life in human societies are now cast in an evolutionary context. In "Evolutionary Theory and the Creation Controversy" the author examines evolutionary theory from a historical perspective, explaining underlying metaphysical backgrounds and fundamental philosophical questions such as the paradoxical problem of change, existence and creation. He introduces the scientists involved, their research results and theories, and discusses the evolution of evolutionary theory against the background of Creationism and Intelligent Design.