In the past ?ve decades considerable attention has been devoted to comp- ite materials. A number of expressions have been suggested by which mac- scopic properties can be predicted when the properties, geometry, and volume concentrations of the constituent components are known. Many expressions are purely empirical or semi-theoretical. Others, however, are theoretically well founded such as the exact results from the following classical boundary studies: Bounds for the elastic moduli of composites made of perfectly coherent homogeneous, isotropic linear elastic phases have been developed by Paul [1] and Hansen [2] for unrestricted phase geometry and by Hashin and Shtrikman [3] for phase geometries, which cause macroscopic homogeneity and isotropy. The composites dealt with in this book are of the latter type. For two speci?c situations (later referred to), Hashin [4] and Hill [5] derived exact - lutionsforthebulkmodulusofsuchmaterials.Hashinconsideredtheso-called Composite Spheres Assemblage (CSA) consisting of tightly packed congruent composite elements made of spherical particles embedded in concentric - trix shells. Hill considered materials in which both phases have identical shear moduli. In the ?eld of predicting the elastic moduli of homogeneous isotropic c- posite materials in general the exact Hashin and Hill solutions are of th- retical interest mainly. Only a few real composites have the geometry de?ned by Hashin or the sti?ness distribution assumed by Hill. The enormous sign- icance, however, of the Hashin/Hill solutions is that they represent bounds which must not be violated by sti?ness predicted by any new theory claiming to consider geometries in general.

The Springer Handbook of Enzymes provides concise data on some 5,000 enzymes sufficiently well characterized - and here is the second, updated edition. Their application in analytical, synthetic and biotechnology processes as well as in food industry, and for medicinal treatments is added. Data sheets are arranged in their EC-Number sequence. The new edition reflects considerable progress in enzymology: the total material has more than doubled, and the complete 2nd edition consists of 39 volumes plus Synonym Index. Starting in 2009, all newly classified enzymes are treated in Supplement Volumes.

Food irradiation, the use of ionizing radiation to destroy harmful biological organism in food, is a safe, proven process that has many useful applications. It has been endorsed by numerous health organizations and has now been approved for many applications by governments around the world.

Electronic Irradiation of Foods describes all the key aspects of electron accelerator technology in detail. It emphasizes the physical science and technology aspects of food irradiation using machine sources of ionizing radiation. The book provides significant technical depth for interested workers and present descriptive, introductory material that should help demystify technology for businessmen to make informed choices regarding important investments decisions.

Introductory chapters summarize the effects of ionizing radiation on biological organisms and the organic compounds comprising foods, and give an overview of the food irradiation process. Subsequent chapters cover the details of the electron beam and x-ray energy deposition, electron accelerator technologies, beam scanning systems, material handling systems, shielding design, and process control considerations. Important appendices cover radiation dosimetry, induced radioactivity, and ozone generation.

Managing the Drug Discovery Process: How to Make It More Efficient and Cost-Effective thoroughly examines the current state of pharmaceutical research and development by providing chemistry-based perspectives on biomedical research, drug hunting and innovation. The book also considers the interplay of stakeholders, consumers, and the drug firm with attendant factors, including those that are technical, legal, economic, demographic, political, social, ecological, and infrastructural. Since drug research can be a high-risk, high-payoff industry, it is important to researchers to effectively and strategically manage the drug discovery process. This book takes a closer look at increasing pre-approval costs for new drugs and examines not only why these increases occur, but also how they can be overcome to ensure a robust pharmacoeconomic future. Written in an engaging manner and including memorable insights, this book is aimed at redirecting the drug discovery process to make it more efficient and cost-effective in order to achieve the goal of saving countless more lives through science. A valuable and compelling resource, this is a must-read for all students and researchers in academia and the pharmaceutical industry.

The book depicts comprehensive studies on thermal decomposition of Kaolinite by different physico-chemical methods carried out by various scientists in last 100 years and results of the studies conducted by author in past 33 years. It also provides a critical analysis of different views on Kaolinite-Mullite reaction series, characterization of controversial spinel phase in Kaolinite-Mullite reaction series and explanation of DTA events of Kaolinite. The book helps both researchers and students to realise the new mechanism of transformation of Kaolinite to Mullite. The new reaction processes discussed in the book also help ceramic experts to synthesize Mullite grains in commercial way for production of Mullite porcelain and Mullite refractory.

A thermodynamically consistent description of the transport across interfaces in mixtures has for a long time been an open issue. This research clarifies that the interface between a liquid and a vapor in a mixture is in local equilibrium during evaporation and condensation. It implies that the thermodynamics developed for interfaces by Gibbs can be applied also away from equilibrium, which is typically the case in reality. A description of phase transitions is of great importance for the understanding of both natural and industrial processes. For example, it is relevant for the understanding of the increase of CO2 concentration in the atmosphere, or improvements of efficiency in distillation columns. This excellent work of luminescent scientific novelty has brought this area a significant step forward. The systematic documentation of the approach will facilitate further applications of the theoretical framework to important problems.

The Physics of Polymers presents the elements of this important segment of material science, focusing on concepts above experimental techniques and theoretical methods. Written for graduate students of physics, material science and chemical engineering and for researchers working with polymers in academia and industry, the book introduces and discusses the basic phenomena which lead to the peculiar physical properties of polymeric systems. The revised and expanded Third Edition includes a new chapter dealing with conjugated polymers, explaining the physical basis of the characteristic electro-optic response, and the spectacular electrical conduction properties of conjugated polymers created by doping.

As semiconductor manufacturers implement copper conductors in advanced interconnect schemes, research and development efforts shift toward the selection of an insulator that can take maximum advantage of the lower power and faster signal propagation allowed by copper interconnects. One of the main challenges to integrating a low-dielectric constant (low-kappa) insulator as a replacement for silicon dioxide is the behavior of such materials during the chemical-mechanical planarization (CMP) process used in Damascene patterning. Low-kappa dielectrics tend to be softer and less chemically reactive than silicon dioxide, providing significant challenges to successful removal and planarization of such materials.

The focus of this book is to merge the complex CMP models and mechanisms that have evolved in the past decade with recent experimental results with copper and low-kappa CMP to develop a comprehensive mechanism for low- and high-removal-rate processes. The result is a more in-depth look into the fundamental reaction kinetics that alter, selectively consume, and ultimately planarize a multi-material structure during Damascene patterning.

The present monograph is devoted to the chemistry of nitroazoles, one of the most interesting series of heteroaromatic compounds. The azoles hold a special position in the chemistry of heterocycles. Their unique properties and specific biological activity attract much attention of research chemists all over the world. During the last years the interest in the chemistry of nitroazoles has increasing. The nitro derivatives of azoles have found a wide application in various fields of industrial chemistry, agriculture, and medicine. Medical products developed by nitroazoles incluce a- mycin, metronidazole, misonidazole, tinidazole, nitazole, etc. , ionic liquids, hi- energy materials, synthons for nanocompounds, universal bases in peptide nucleic acids, plant growth regulators, and intermediates for organic synthesis. The investigations in the field of energetic compounds have received enormous interest in recent years. Energetic materials on the base nitroazoles - explosives, propellants, and pyrotechnics - are widely used for both civilian and military applications. Nitroazoles, especially polynitroazoles, possess higher heat of for- tion, density, and oxygen balance than their carbocyclic analogs. A number of ongoing research programs worldwide are aimed for the development of new explosives and propellants with higher performance characteristics or enhanced insensitivity to thermal or shock insults and pyrotechnics with reduced smoke. The preparation of nitroazoles demonstrates its great synthetic potential. At the same time, feasibility and availability of the starting molecules make this strategy a p- erful method for high-energy material construction.

Expectations drive our lives and actions. Our interpretation of the scene out in front governs whether or not we eat and whether or not we patronize a store or restaurant. The activity of the moment is pursued not only for duty or immediate pleasure but also with the dread, excitement, or merely boredom that lies ahead. The stimulus provided by the total appearance of the object or scene engenders expectations of the outcome of our involvement with the object or event.

Throughout the food chain, expectations are at the heart of quality judgements and price. On entering a restaurant or pub we may subconsciously judge qualities such as cleanliness, comfort, privacy, and quality. A major part of these judgements are responses to the visual properties of the space.

This book tackles expectations and how they arise, expectations associated with strangers involved in the food industry, with the business faAade, advertisement and packaging, as well as expectations engendered in store and restaurant and from the food itself. This holistic approach has been taken because total appearance images and expectations are critical in separate and interlinking ways to all aspects of food research, development, production, marketing, sales and preparation, as well as consumption. Above all, they are critical to each individual customer whether they are in the kitchen, store, restaurant or pub.

This book seeks to help those in all areas of industry who contribute to the visual stimulus experienced by the customer. These include architects, store designers, and food producers, whether they be banquet chef or manufacturer, as well as those in advertising and packaging or having responsibilityfor training customer contact staff. It will also serve as a text for students and graduates of food science, marketing in its widest sense, retailing, and those concerned with food and its presentation.

Although this book is directed at members of the food industry, the philosophy, approach, and interpretation apply to all industries and service sectors that depend on a person's visual appraisal of an object, scene, or situation.

This thesis provides the first successful study of jump diffusion processes in glasses on the atomic scale, utilizing a novel coherent technique. This new method, called atomic-scale X-ray Photon Correlation Spectroscopy or aXPCS, has only recently been proven to be able to capture diffusion processes with atomic resolution in crystal systems. With this new toolkit for studying atomic diffusion in amorphous systems, new insight into basic processes in a wide range of technically relevant materials, like fast ionic conductors, can be obtained.

This work presents up-to-date information on chemical, pharmacological, clinical studies and historical uses of common dietary Chinese herbs. Authored by native experts in the field, the reader is introduced to each herb with a brief chronological review of Chinese literature on dietary herb uses, with chapters dedicated to each selected herb including color photos for each herb. In addition, Chinese characters as well as the Latin botanical name indices, and chemical structures for the known active compounds are also provided. The clear layout examines the health benefits that have been studied for centuries, including current clinical and toxicological data. A wide range of Traditional Chinese Medicine (TCM) herbs are investigated for their suitability into daily diets for maintaining general wellness or disease prevention. In the past decades, natural health products, dietary supplements, functional foods, or nutraceuticals have emerged in the West due to the increasing demand for non-pharmaceutical healthcare products. Traditional Chinese Medicine disease prevention and treatment incorporates the use of foods, and herbal medicine in an integrated manner, and thus the dietary Chinese herbs in used in TCM for thousands of years could be sources for developing new, effective, and safe ingredients to capture the rapidly expanding opportunity in the global market place.

Plant tissue culture and advanced biotechnologies have proven to be influential tools that complement conventional breeding and accelerate development of many medicinal plants. Various approaches, such as pathway engineering, precursor feeding, transformation, elicitation with biotic and abiotic elicitors and scaling up in bioreactors, have been explored to improve the production of secondary metabolites from different medicinal plants. This book provides a comprehensive description of various studies, carried out on in vitro culture and hairy root cultures of Catharanthus roseus, Silybum marianum and Digitalis species which have been considered as alternative sources for the production of anti-tumour compounds, flavonolignans and cardenolides. Specific focus is on elicitation strategy for increasing production of bioactive compounds of C. roseus L., S. marianum and Digitalis species to overcome the constrains of conventional propagation. This book is valuable for researchers or students working on medicinal plants, phytochemistry, and plant tissue culture. It also serves as a reference for the pharmaceutical industry.

The book is divided in 3 sections, each containing several chapters: Section 1 includes chapters that identify and discuss several ethical issues along the food chain, with particular detail of issues in the food industry and in consumer behavior; Section 2 includes chapters that present the basis of a code of conduct in the food profession as well as the description of existing codes of conduct of food industry and food scientist professionals, including ethics of publishing, and also ethics in risk communication; Section 3 includes chapters based on case studies with examples of teaching approaches currently used in teaching food ethics, easy to implement and already tested and confirmed as successful examples that engage students in this topic. Although professional ethics in food supply chain is claimed as an essential topic to be addressed in any degree program, few higher education institutions that currently include a module on ethics in their study programs. In g eneral, it is argued that ethics is a topic addressed along the curriculum and embedded in the contents of the modules. However, ethics, for its importance, needs a different teaching and educational approach, and this book achieves that..

These proceedings comprise the peer-reviewed contributions submitted to the 11th International Congress for Applied Mineralogy (ICAM) held July 5-10, 2013, at the Southwest University of Science and Technology (SWUST) in Mianyang, China. The biennial ICAM is the most important gathering of applied mineralogists, organized every other year by the ICAM-Council. The multidisciplinary research presented in this book will be of interest to scientists and professionals dealing with topics like environmental and medical mineralogy; industrial minerals; bio-minerals and biomaterials; advanced materials; process mineralogy; mining and metallurgy; cultural heritage; the interaction of minerals with microorganisms; and solid waste treatment and recycling, including genetic mineralogy. "The field of applied mineralogy has been able to match society's pace by continuously reinventing itself, quickly adopting new technologies and instrumentation as they became available and putting them to work for the service of mankind living in a world that heavily relies on minerals. Over the past few decades, applied mineralogy has evolved into a cutting- edge discipline that leads the way for science, engineering and research and development to benefit society. Contrary to popular belief, mineral resources are limited, and we have an obligation to our heirs to use them responsibly." Dr. Maarten A.T.M. Broekmans Post-President ICAM Council

Chemical Vapor Deposition Polymerization - The Growth and Properties of Parylene Thin Films is intended to be valuable to both users and researchers of parylene thin films. It should be particularly useful for those setting up and characterizing their first research deposition system. It provides a good picture of the deposition process and equipment, as well as information on system-to-system variations that is important to consider when designing a deposition system or making modifications to an existing one. Also included are methods to characterizae a deposition system's pumping properties as well as monitor the deposition process via mass spectrometry. There are many references that will lead the reader to further information on the topic being discussed.
This text should serve as a useful reference source and handbook for scientists and engineers interested in depositing high quality parylene thin films.

Twice reprinted and now also available in a paperback edition, this book has already proved invaluable to a wide range of readers. Written by a scientist for scientists and technical people, it goes beyond the subject matter indicated by the title, filling the gap which previously existed in the available technical literature. It includes a wealth of information for physicists, chemists and engineers who need to know more about thin films for research purposes, or who want to use this special form of solid material to achieve a variety of application-oriented goals.

This thesis addresses the development of a new force spectroscopy tool, correlation force spectroscopy (CFS) for the measurement of the properties of very small volumes of material (molecular to m3) at kHz-MHz frequency range. CFS measures the simultaneous thermal fluctuations of two closely-spaced atomic force microscopy (AFM) cantilevers. CFS then calculates the cross-correlation in the thermal fluctuations that gives the mechanical properties of the matter that spans the gap of the two cantilevers. The book also discusses development of CFS, its advantages over AFM, and its application in single molecule force spectroscopy and micro-rheology.

Personalized medicine, which simply means selection of treatment best suited for an individual, involves integration and translation of several new technologies in clinical care of patients. The scope is much broader than indicated by the term genomic medicine because many non-genomic factors are taken into consideration in developing personalized medicine. Basic technologies for personalized medicine, of which molecular diagnostics has the biggest share, are mentioned briefly and appropriate references are given for further information. Commercial aspects are discussed briefly in a chapter and detailed analysis of markets and companies involved in personalized medicine is presented in a special report on this topic.

There is increasing interest in personalized medicine. Considerable advances have taken place in molecular biology and biotechnology to make personalized medicine a viable option, but some misconceptions still exist, both in the academic and commercial sectors. There is lack of a suitable source of information that provides both the fundamentals as well as applications of personalized medicine. As the latest version of the first monograph on personalized medicine published in 1998, this volume, Textbook of Personalized Medicine, summarizes the author's efforts during the past decade, as well as reviews selected studies done during this period in a readable format for the physicians and scientists. It is hoped that physicians, pharmacists, scientists and interested lay readers with basic scientific knowledge will find this book useful.

This book provides knowledge on the finishing of substrates with a functionalising coating, emphasizing on technical textiles. The spectrum of topics covers different substrates and coating materials, process engineering and equipment components as well as complex machinery. The reader is presented with an overview of the technical capabilities of substrate coating, enabling the practitioner to design and implement new products. Furthermore the author goes into detail on various air pollution control procedures and economic issues of asset valuation.

Currently, there is no one book or textbook that covers all aspects of retail food safety. It is becoming apparent that a number of issues relating to retail food safety have come to the forefront in some jurisdictions of late. For example, a recent USDA risk assessment has pointed out that issues occurring at USA retail appear to be critical in terms of contamination of deli-meat. As well, a large listeriosis outbreak in Quebec pointed to retail cross-contamination as a key issue. In terms of sanitation, a number of advances have been made, but these have not all been synthesized together in one chapter, with a focus on retail. In addition, the whole area of private standards and the Global Food Safety Initiative (GFSI) have come to the forefront of late and these as well will be explored in great detail. Other aspects related to the safety of important food commodities such as seafood, meat, produce and dairy will also be discussed and salient areas addressed.

The emphasis in degradable polymers has changed since the first edition of this book. Biomedical and agricultural applications remain important topics of scientific and commercial interest in the second edition. However, an increased emphasis on composting as a means of recovering value from wastes has led to a new impetus to understand how plastics degrade in the environment and the implication of this for international standards. Polymers based on renewable resources are also a major topic in this edition but the debate continues about their long-term sustainability and ecological advantages over degradable man-made polymers.

Degradable Polymers will be of interest not only to academic and industrial scientists working on packaging, agricultural and medical applications of plastics but also to students of environmental science and legislators concerned with the effects of man-made materials in the environment.

This book covers fundamental principles and numerical methods relevant to the modeling of the injection molding process. As injection molding processing is related to rheology, mechanical and chemical engineering, polymer science and computational methods, and is a rapidly growing field, the book provides a multidisciplinary and comprehensive introduction to the subjects required for an understanding of the complex process. It addresses the up-to-date status of fundamental understanding and simulation technologies, without losing sight of still useful classical approaches. The main chapters of the book are devoted to the currently active fields of flow-induced crystallization and orientation evolution of fiber suspensions, respectively, followed by detailed discussion of their effects on mechanical property, shrinkage and warpage of injection-molded products. The level of the proposed book will be suitable for interested scientists, R&D engineers, application engineers, and graduate students in engineering.

This second edition of the textbook presents a systematic introduction to the structural mechanics of composite components. The book focusses on modeling and calculation of sandwiches and laminated composites i.e. anisotropic material. The new edition includes an additional chapter covering the latest advances in both research and applications, which are highly relevant for readers. The textbook is written for use not only in engineering curricula of aerospace, civil and mechanical engineering, but also for materials science and applied mechanics. Furthermore, it addresses practicing engineers and researchers. No prior knowledge of composite materials and structures is required for the understanding of its content. The book is close to classical courses of "Strength of Materials" and "Theory of Beams, Plates and Shells" but it extends the classic content on two topics: the linear elastic material behavior of isotropic and non-isotropic structural elements, and inhomogeneous material properties in the thickness direction. The Finite Element Analysis of laminate and sandwich structures is briefly presented. Many solved examples illustrate the application of the techniques learned.

This book provides a fundamental understanding of physical properties of foods. It is the first textbook in this area and combines engineering concepts and physical chemistry. Basic definitions and principles of physical properties are discussed as well as the importance of physical properties in the food industry and measurement methods. In addition, recent studies in physical properties are summarized. The material presented is helpful for students to understand the relationship between physical and functional properties of raw, semi-finished, and processed food in order to obtain products with desired shelf-life and quality.