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Nitroazoles: Synthesis, Structure and Applications (Hardcover, 2009 ed.)
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Nitroazoles: Synthesis, Structure and Applications (Hardcover, 2009 ed.)
Series: Topics in Applied Chemistry
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The present monograph is devoted to the chemistry of nitroazoles,
one of the most interesting series of heteroaromatic compounds. The
azoles hold a special position in the chemistry of heterocycles.
Their unique properties and specific biological activity attract
much attention of research chemists all over the world. During the
last years the interest in the chemistry of nitroazoles has
increasing. The nitro derivatives of azoles have found a wide
application in various fields of industrial chemistry, agriculture,
and medicine. Medical products developed by nitroazoles incluce a-
mycin, metronidazole, misonidazole, tinidazole, nitazole, etc. ,
ionic liquids, hi- energy materials, synthons for nanocompounds,
universal bases in peptide nucleic acids, plant growth regulators,
and intermediates for organic synthesis. The investigations in the
field of energetic compounds have received enormous interest in
recent years. Energetic materials on the base nitroazoles -
explosives, propellants, and pyrotechnics - are widely used for
both civilian and military applications. Nitroazoles, especially
polynitroazoles, possess higher heat of for- tion, density, and
oxygen balance than their carbocyclic analogs. A number of ongoing
research programs worldwide are aimed for the development of new
explosives and propellants with higher performance characteristics
or enhanced insensitivity to thermal or shock insults and
pyrotechnics with reduced smoke. The preparation of nitroazoles
demonstrates its great synthetic potential. At the same time,
feasibility and availability of the starting molecules make this
strategy a p- erful method for high-energy material construction.
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