Rapid advances in high-throughput genome sequencing technologies foreshadow a near-future in which millions of individuals will gain affordable access to their complete genome sequence. This promises to offer unprecedented insights into the fundamental biological nature of ourselves and our species: where we came from, how we begin our lives, how we develop and grow, how we interact with our environment, how we get sick, how we get well, and how we age. Personal genomics is an essential component of the inevitable transition towards personalized health and medicine. As the medical establishment begins to explore and evaluate the role of personal genomics in health and medicine, both clinicians and patients alike will gain from becoming well versed in both the power and the pitfalls of personal genomic information. Furthermore, it is likely that all students of the biomedical sciences will soon be required to gain crucial understanding in the emerging field of personal genomics. Exploring Personal Genomics provides a novel, inquiry-based approach to the understanding and interpretation of the practical, medical, physiological, and societal aspects of personal genomic information. The material is presented in two parts: the first provides readers of all backgrounds with a fundamental understanding of the biology of human genomes, information on how to obtain and understand digital representations of personal genomic data, tools and techniques for exploring the personal genomics of ancestry and genealogy, discovery and interpretation of genetic trait associations, and the role of personal genomics in drug response. The second part offers more advanced readers an understanding of the science, tools, and techniques for investigating interactions between a personal genome and the environment, connecting DNA to physiology, and assessing rare variants and structural variation. This book aims to support undergraduate and graduate studies in medicine, genetics, molecular biology, and bioinformatics. Additionally, the design of the content is such that medical practitioners, professionals working in the biomedical sciences or related fields, and motivated lay individuals interested in exploring their personal genetic data should find it relevant and approachable.

Through an unprecedented multidisciplinary and global approach, this book documents the dramatic several-thousand-year history of leprosy using bioarchaeological, clinical, and historical information from a wide variety of contexts, dispelling many long-standing myths about the disease. Drawing on her 30 years of research on the infection, Charlotte Roberts begins by outlining its bacterial causes, how it spreads, and how it affects the body. She then considers its diagnosis and treatment, both historically and in the present. She also looks at the methods and tools used by paleopathologists to identify signs of leprosy in skeletons. Examining evidence in human remains from many countries, particularly in Europe and including Britain, Hungary, and Sweden, Roberts demonstrates that those affected were usually buried in the same cemeteries as their communities, contrary to the popular belief that they were all ostracized or isolated from society into leprosy hospitals. Other myths addressed by Roberts include the assumptions that leprosy can't be cured, that leprosy is no longer a problem today, and that what is called "leprosy" in the Bible is the same illness as the disease with that name now. Roberts concludes by projecting the future of leprosy, arguing that researchers need to study the disease through an ethically grounded evolutionary perspective. Importantly, she advises against use of the word "leper" to avoid perpetuating stigma today surrounding people with the infection and resulting disabilities. Leprosy will stand as the authoritative source on the subject for years to come. A volume in the series Bioarchaeological Interpretations of the Human Past: Local, Regional, and Global Perspectives, edited by Clark Spencer Larsen.

The age-friendly community movement is a global phenomenon, currently growing with the support of the WHO and multiple international and national organizations in the field of aging. Drawing on an extensive collection of international case studies, this volume provides an introduction to the movement. The contributors - both researchers and practitioners - touch on a number of current tensions and issues in the movement and offer a wide-ranging set of recommendations for advancing age-friendly community development. The book concludes with a call for a radical transformation of a medical and lifestyle model of aging into a relational model of health and social/individual wellbeing.

This book explores Native American literary responses to biomedical discourses and biomedicalization processes as they circulate in social and cultural contexts. Native American communities resist reductivism of biomedicine that excludes Indigenous (and non-Western) epistemologies and instead draw attention to how illness, healing, treatment, and genetic research are socially constructed and dependent on inherently racialist thinking. This volume highlights how interventions into the hegemony of biomedicine are vigorously addressed in Native American literature. The book covers tuberculosis and diabetes epidemics, the emergence of Native American DNA, discoveries in biotechnology, and the problematics of a biomedical model of psychiatry. The book analyzes work by Louise Erdrich, Sherman Alexie, LeAnne Howe, Linda Hogan, Heid E. Erdrich, Elissa Washuta and Frances Washburn. The book will appeal to scholars of Native American and Indigenous Studies, as well as to others with an interest in literature and medicine.

In a world now filled with more people who are overweight than underweight, public health and medical perspectives paint obesity as a catastrophic epidemic that threatens to overwhelm health systems and undermine life expectancies globally. In many societies, being obese also creates profound personal suffering because it is so culturally stigmatized. Yet despite loud messages about the health and social costs of being obese, weight gain is a seemingly universal aspect of the modern human condition. Grounded in a holistic anthropological approach and using a range of ethnographic and ecological case studies, Obesity shows that the human tendency to become and stay fat makes perfect sense in terms of evolved human inclinations and the physical and social realities of modern life. Drawing on her own fieldwork in the rural United States, Mexico, and the Pacific Islands over the last two decades, Alexandra A. Brewis addresses such critical questions as why obesity is defined as a problem and why some groups are so much more at risk than others. She suggests innovative ways that anthropology and other social sciences can use community-based research to address the serious public health and social justice concerns provoked by the global spread of obesity.

Abject Relations presents an alternative approach to anorexia nervosa, long considered the epitome of a Western obsession with individualism, beauty, self-control, and autonomy. Through detailed ethnographic investigations, Megan Warin looks at the heart of what it means to live with anorexia on a daily basis. Participants describe difficulties with social relatedness, not being at home in their body, and feeling disgusting and worthless. For them, anorexia becomes a seductive and empowering practice that cleanses bodies of shame and guilt, becomes a friend and support, and allows them to forge new social relations. Unraveling anorexia's complex relationships and contradictions, Warin constructs a new theoretical perspective rooted in a socio-cultural context of bodies and gender. Abject Relations departs from conventional psychotherapy approaches and offers a different "logic," one that involves the shifting forces of power, disgust, and desire. It provides new ways of thinking that may have implications for future treatment regimes. Megan Warin is a social anthropologist in the Discipline of Gender, Work, and Social Inquiry at the University of Adelaide. She has previously worked across anthropology, psychiatry, and public health at various institutions, including Durham University, the University of Adelaide, and Flinders University of South Australia. Praise for Abject Relations: "Warin has taken the topic of anorexia, which many of us feel that we know something about, and brilliantly cast a whole new light on it. Through vivid ethnography and evocative prose, she ensures that you won't think about anorexia or those affected by it in quite the same way ever again."-C. H. Browner, UCLA School of Medicine "Anthropologist Megan Warin combines rich multisited ethnographic research on anorexic women's lived experiences with a sophisticated theoretical approach based on concepts of abjection and relatedness to offer fascinating and original insights into anorexia nervosa."-Carole M. Counihan, author of The Anthropology of Food and Body: Gender, Meaning, and Power

In the fertility and cosmetics industries, women's body products - such as urine, eggs, and placentas - have moved from being seen as waste to becoming valuable ingredients. Taking a sociological and anthropological perspective, the author focuses in particular on the role that countries like Denmark, Spain, the Netherlands, and Japan play in the reproductive products industry, and discusses the moral limits of the cultural and rhetorical trajectories that turn women's body products into internationally mobile substances.

In the wake of structural adjustment programs in the 1980s and health reforms in the 1990s, the majority of sub-Saharan African governments spend less than ten dollars per capita on health annually, and many Africans have limited access to basic medical care. Using a community-level approach, anthropologist Ellen E. Foley analyzes the implementation of global health policies and how they become intertwined with existing social and political inequalities in Senegal. ""Your Pocket Is What Cures You"" examines qualitative shifts in health and healing spurred by these reforms, and analyzes the dilemmas they create for health professionals and patients alike. It also explores how cultural frameworks, particularly those stemming from Islam and Wolof ethnomedicine, are central to understanding how people manage vulnerability to ill health. While offering a critique of neoliberal health policies, ""Your Pocket Is What Cures You"" remains grounded in ethnography to highlight the struggles of men and women who are precariously balanced on twin precipices of crumbling health systems and economic decline. Their stories demonstrate what happens when market-based health reforms collide with material, political, and social realities in African societies.

Babies are not simply born-they are made through cultural and social practices. Based on rich empirical work, this book examines the everyday experiences that mark pregnancy in the US today, such as reading pregnancy advice books, showing ultrasound "baby pictures" to friends and co-workers, and decorating the nursery in anticipation of the new arrival. These ordinary practices of pregnancy, the author argues, are significant and revealing creative activities that produce babies. They are the activities through which babies are made important and meaningful in the lives of the women and men awaiting the child's birth. This book brings into focus a topic that has been overlooked in the scholarship on reproduction and will be of interest to professionals and expectant parents alike.

Modern medicine has penetrated Bedouin tribes in the course of rapid urbanization and education, but when serious illnesses strike, particularly in the case of incurable diseases, even educated people turn to traditional medicine for a remedy. Over the course of 30 years, the author gathered data on traditional Bedouin medicine among pastoral-nomadic, semi-nomadic, and settled tribes. Based on interviews with healers, clients, and other active participants in treatments, this book will contribute to renewed thinking about a synthesis between traditional and modern medicine - to their reciprocal enrichment.

Human Origins brings together new thinking by social anthropologists and other scholars on the evolution of human culture and society. No other discipline has more relevant expertise to consider the emergence of humans as the symbolic species. Yet, social anthropologists have been conspicuously absent from debates about the origins of modern humans. These contributions explore why that is, and how social anthropology can shed light on early kinship and economic relations, gender politics, ritual, cosmology, ethnobiology, medicine, and the evolution of language.

This book sets out to define and consolidate the field of bioinformation studies in its transnational and global dimensions, drawing on debates in science and technology studies, anthropology and sociology. It provides situated analyses of bioinformation journeys across domains and spheres of interpretation. As unprecedented amounts of data relating to biological processes and lives are collected, aggregated, traded and exchanged, infrastructural systems and machine learners produce real consequences as they turn indeterminate data into actionable decisions for states, companies, scientific researchers and consumers. Bioinformation accrues multiple values as it transverses multiple registers and domains, and as it is transformed from bodies to becoming a subject of analysis tied to particular social relations, promises, desires and futures. The volume harnesses the anthropological sensibility for situated, fine-grained, ethnographically grounded analysis to develop an interdisciplinary dialogue on the conceptual, political, social and ethical dimensions posed by bioinformation.

The social anthropology of sickness and health has always been concerned with religious cosmologies: how societies make sense of such issues as prediction and control of misfortune and fate; the malevolence of others; the benevolence (or otherwise) of the mystical world; local understanding and explanations of the natural and ultra-human worlds. This volume presents differing categorizations and conflicts that occur as people seek to make sense of suffering and their experiences. Cosmologies, whether incorporating the divine or as purely secular, lead us to interpret human action and the human constitution, its ills and its healing and, in particular, ways which determine and limit our very possibilities.

Umhlonyane, also known as Artemisia afra, is one of the oldest and best-documented indigenous medicines in South Africa. This bush, which grows wild throughout the sub-Saharan region, smells and tastes like "medicine," thus easily making its way into people's lives and becoming the choice of everyday healing for Xhosa healer-diviners and Rastafarian herbalists. This "natural" remedy has recently sparked curiosity as scientists search for new molecules against a tuberculosis pandemic while hoping to recognize indigenous medicine. Laplante follows umhlonyane on its trails and trials of becoming a biopharmaceutical - from the "open air" to controlled environments - learning from the plant and from the people who use it with hopes in healing.

Based on several years of ethnographic fieldwork, the book explores life in and around a Luo-speaking village in western Kenya during a time of death. The epidemic of HIV/AIDS affects every aspect of sociality and pervades villagers' debates about the past, the future and the ethics of everyday life. Central to such debates is a discussion of touch in the broad sense of concrete, material contact between persons. In mundane practices and in ritual acts, touch is considered to be key to the creation of bodily life as well as social continuity. Underlying the significance of material contact is its connection with growth - of persons and groups, animals, plants and the land - and the forward movement of life more generally. Under the pressure of illness and death, economic hardship and land scarcity, as well as bitter struggles about the relevance and application of Christianity and 'Luo tradition' in daily life, people find it difficult to agree about the role of touch in engendering growth, or indeed about the aims of growth itself.

Breastfeeding and child feeding at the center of nurturing practices, yet the work of nurture has escaped the scrutiny of medical and social scientists. Anthropology offers a powerful biocultural approach that examines how custom and culture interact to support nurturing practices. Our framework shows how the unique constitutions of mothers and infants regulate each other. The Dance of Nurture integrates ethnography, biology and the political economy of infant feeding into a holistic framework guided by the metaphor of dance. It includes a critique of efforts to improve infant feeding practices globally by UN agencies and advocacy groups concerned with solving global nutrition and health problems.

"[S]heds light not only on the obstacles to making motherhood safer, but to improving the health of poor populations in general."-Social Anthropology Since 1987, when the global community first recognized the high frequency of women in developing countries dying from pregnancy-related causes, little progress has been made to combat this problem. This study follows the global policies that have been implemented in Solola, Guatemala in order to decrease high rates of maternal mortality among indigenous Mayan women. The author examines the diverse meanings and understandings of motherhood, pregnancy, birth and birth-related death among the biomedical personnel, village women, their families, and midwives. These incongruous perspectives, in conjunction with the implementation of such policies, threaten to disenfranchise clients from their own cultural understandings of self. The author investigates how these policies need to meld with the everyday lives of these women, and how the failure to do so will lead to a failure to decrease maternal deaths globally. From the Introduction: An unspoken effect of reducing maternal mortality to a medical problem is that life and death become the only outcomes by which pregnancy and birth are understood. The specter of death looms large and limits our full exploration of either our attempts to curb maternal mortality, or the phenomenon itself. Certainly women's survival during childbirth is the ultimate measure of success of our efforts. Yet using pregnancy outcomes and biomedical attendance at birth as the primary feedback on global efforts to make pregnancy safer is misguided.

How does the need to obtain and deliver health services engender particular (im)mobility forms? And how is mobility experienced and imagined when it is required for healthcare access or delivery? Guided by these questions, Healthcare in Motion explores the dynamic interrelationship between mobility and healthcare, drawing on case studies from across the world and shedding light on the day-to-day practices of patients and professionals.

Babies are not simply born-they are made through cultural and social practices. Based on rich empirical work, this book examines the everyday experiences that mark pregnancy in the US today, such as reading pregnancy advice books, showing ultrasound "baby pictures" to friends and co-workers, and decorating the nursery in anticipation of the new arrival. These ordinary practices of pregnancy, the author argues, are significant and revealing creative activities that produce babies. They are the activities through which babies are made important and meaningful in the lives of the women and men awaiting the child's birth. This book brings into focus a topic that has been overlooked in the scholarship on reproduction and will be of interest to professionals and expectant parents alike.

Minority populations are often regarded as being 'hard to reach' and evading state expectations of health protection. This ethnographic and archival study analyses how devout Jews in Britain negotiate healthcare services to preserve the reproduction of culture and continuity. This book demonstrates how the transformative and transgressive possibilities of technology reveal multiple pursuits of protection between this religious minority and the state. Making Bodies Kosher advances theoretical perspectives of immunity, and sits at the intersection of medical anthropology, social history and the study of religions.

The technological capacity to transform biology - repairing, reshaping and replacing body parts, chemicals and functions - is now part of our lives. Humanity is confronted with a variety of affordable and non-invasive 'enhancement technologies': anti-ageing medicine, aesthetic surgery, cognitive and sexual enhancers, lifestyle drugs, prosthetics and hormone supplements. This collection focuses on why people find these practices so seductive and provides ethnographic insights into people's motives and aspirations as they embrace or reject enhancement technologies, which are closely entangled with negotiations over gender, class, age, nationality and ethnicity.

Sylhet, the area of Bangladesh most closely associated with overseas migration, has seen an increase in remittances sent home from abroad, introducing new inequalities. Social change has also been mediated by the global forces of Western biomedicine and orthodox Islam. This book examines the effects of these modernizing trends on mental health and on local, traditional healing as the new inequalities have exacerbated existing social tensions and led to increased vulnerability to mental illness. It is the young women of Sylhet who are most affected. The global economy has increased competition for resources and led to marriage being seen as a route to economic advancement. Parents prefer to give their daughters in marriage to families that will widen their social contacts and enhance their economic and social standing. Accordingly, the young wife's outsider status (and hence vulnerability to mental illness) has increased as it is no longer customary to give daughters in marriage to local kin. Yet, patients and their families do not work out tensions passively. They are active agents in the construction of their own diagnosis. The extent to which patients act or are acted upon is an investigation that runs throughout the book.

Alyson Callan is a psychiatrist and anthropologist. She currently works as a consultant psychiatrist in Brent for the Central and North West London NHS Foundation Trust.

All cultures are concerned with the business of childbirth, so much so that it can never be described as a purely physiological or even psychological event. This volume draws together work from a range of anthropologists and midwives who have found anthropological approaches useful in their work. Using case studies from a variety of cultural settings, the writers explore the centrality of the way time is conceptualized, marked and measured to the ways of perceiving and managing childbirth: how women, midwives and other birth attendants are affected by issues of power and control, but also actively attempt to change established forms of thinking and practice. The stories are engaging as well as critical and invite the reader to think afresh about time, and about reproduction.

What does it mean to be a man in our biomedical day and age? Through ethnographic explorations of the everyday lives of Danish sperm donors, Being a Sperm Donor explores how masculinity and sexuality are reconfigured in a time in which the norms and logics of (reproductive) biomedicine have become ordinary. It investigates men's moral reasoning regarding donation, their handling of transgressive experiences at the sperm bank, and their negotiations of gender, sexuality, intimacy, and relatedness, showing how the socio-cultural and political dimensions of (reproductive) biomedicine become intertwined with men's intimate sense of self.

Bioarchaeology covers the history and general theory of the field plus the recovery and laboratory treatment of human remains. Bioarchaeology is the study of human remains in context from an archaeological and anthropological perspective. The book explores, through numerous case studies, how the ways a society deals with their dead can reveal a great deal about that society, including its religious, political, economic, and social organizations. It details recovery methods and how, once recovered, human remains can be analyzed to reveal details about the funerary system of the subject society and inform on a variety of other issues, such as health, demography, disease, workloads, mobility, sex and gender, and migration. Finally, the book highlights how bioarchaeological techniques can be used in contemporary forensic settings and in investigations of genocide and war crimes. In Bioarchaeology, theories, principles, and scientific techniques are laid out in a clear, understandable way, and students of archaeology at undergraduate and graduate levels will find this an excellent guide to the field.